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  1. According to the Feeding Infants and Toddlers Study (FITS), the percentage of older infants consuming infant cereal has declined from 72% of 6–11.9 month old infants in 2002 to 52% in 2016. This is especially ...

    Authors: Kristen Finn, Sarah Quick, Andrea Anater, Joel Hampton, Brian Kineman and William Klish
    Citation: BMC Pediatrics 2022 22:219
    Content type: Research Published on:

  2. The role of serum Procalcitonin (PCT) in adults in diagnosis of Community acquired pneumonia (CAP) is well established, however, role in pediatric CAP remains controversial.

    Authors: Vinod H. Ratageri, Puspha Panigatti, Aparna Mukherjee, Rashmi R. Das, Jagdish Prasad Goyal, Javeed Iqbal Bhat, Bhadresh Vyas, Rakesh Lodha, Deepak Singhal, Prawin Kumar, Kuldeep Singh, Samarendra Mahapatro, Bashir Ahmad Charoo, S. K. Kabra and K. R. Jat
    Citation: BMC Pediatrics 2022 22:217
    Content type: Research Published on:

  3. Hirschsprung disease (HSCR) is a complex genetic disorder characterized by the lack of ganglion cells in the intestines. A current study showed that the NRG1 rare variant frequency in Indonesian patients with HSC...

    Authors: Gunadi, Alvin Santoso Kalim, Marcellus, Nova Yuli Prasetyo Budi and Kristy Iskandar
    Citation: BMC Pediatrics 2022 22:216
    Content type: Research Published on:

  4. The timing of adiposity peak (AP) or adiposity rebound (AR) is a determinant of overweight or obesity in adolescence and adulthood. However, limited studies have reported the association in young school-age ch...

    Authors: Dan Lin, Di-di Chen, Jun Huang, Yun Li, Xiao-sa Wen and Hui-jing Shi
    Citation: BMC Pediatrics 2022 22:215
    Content type: Research Published on:

  5. Orofacial clefts (OFCs) are the commonest congenital anomalies of the head and neck. Their aetiology is multifactorial, and prevalence has a geographical variation. This study sought to describe OFC cases that...

    Authors: Prosperity A. Sithole, Palesa Motshabi-Chakane and Michel K. Muteba
    Citation: BMC Pediatrics 2022 22:214
    Content type: Research Published on:

  6. Early morning sunlight exposure for infants is a good practice to prevent rickets and alleviate the problem of vitamin D deficiency. Rickets is a major public health problem in many countries especially in dev...

    Authors: Eyasu Alem Lake, Birhanu Wondimeneh Demissie, Natneal Atnafu Gebeyehu, Gedion Asnake Azeze, Kelemu Abebe Gelaw, Robera Olana Fite, Lielt Gebreselassie Gebrekirstos, Tesfaye Yitna Chichiabellu and Mistire Teshome Guta
    Citation: BMC Pediatrics 2022 22:213
    Content type: Research Published on:

  7. Risky media use in terms of accumulating too much time in front of screens and usage before bedtime in early childhood is linked to developmental delays, reduced sleep quality, and unhealthy media use in later...

    Authors: C. Fitzpatrick, M. L Almeida, E. Harvey, G. Garon-Carrier, F. Berrigan and M Asbridge
    Citation: BMC Pediatrics 2022 22:212
    Content type: Research Published on:

  8. Necrotizing enterocolitis (NEC) is one of serious gastrointestinal inflammatory diseases in newborn infants, with a high morbidity and mortality. Red blood cell transfusion (RBCT) plays a controversial and dou...

    Authors: Lijuan Luo, Xingling Liu, Huan Yu, Mei Luo, Wen Jia, Wenbin Dong and Xiaoping Lei
    Citation: BMC Pediatrics 2022 22:211
    Content type: Research Published on:

  9. Although advance care planning (ACP) has been widely recommended to support patient and family engagement in understanding the patient’s values, preferences and goals of care, there are only a few models in pa...

    Authors: Anne van Driessche, Joni Gilissen, Aline De Vleminck, Marijke Kars, Jurrianne Fahner, Jutte van der Werff ten Bosch, Luc Deliens, Joachim Cohen and Kim Beernaert
    Citation: BMC Pediatrics 2022 22:210
    Content type: Research Published on:

  10. Childhood overweight and obesity is one of the most challenging public health problems facing both developed and developing countries. Several studies carried worldwide assessed predisposing risk factors for c...

    Authors: Helene Barbe Zoghby, Elsa Sfeir, Marwan Akel, Diana Malaeb, Sahar Obeid and Souheil Hallit
    Citation: BMC Pediatrics 2022 22:209
    Content type: Research Published on:

  12. The problem of cardiovascular diseases and lack of adequate information about the blood pressure profiles among children in South Africa has enormous consequences for public health and the general well-being o...

    Authors: Howard Gomwe, Eunice Seekoe, Philemon Lyoka and Chioneso Show Marange
    Citation: BMC Pediatrics 2022 22:207
    Content type: Research Published on:

  13. Precision treatment of pediatric diabetic ketoacidosis (DKA) has been the focus of research for decades. Whether the timing of the initiation of dietary intake contributes to DKA correction is ignored.

    Authors: Xuewen Yuan, Jieguo Wang, Xiaofeng Chen, Wu Yan, Qing Niu, Ning Tang, Ming Zhi Zhang, Wei Gu and Xu Wang
    Citation: BMC Pediatrics 2022 22:206
    Content type: Research Published on:

  14. Even though child mortality decreased greatly (44%, since 1990), children in developing countries are eight times more likely to die before they attain their five years birthday. When comparing under-five mort...

    Authors: Nigusie Selomon Tibebu, Tigabu Desie Emiru, Chalie Marew Tiruneh, Adane Birhanu Nigat, Moges wubneh Abate, Bisrat Dessie Getu and Amsalu Belete Mekonnen
    Citation: BMC Pediatrics 2022 22:205
    Content type: Research Published on:

  15. Acute otitis media (AOM) remains a common infection in children despite the introduction of pneumococcal conjugate vaccines. This study estimated AOM incidence rates (IRs) over time in children < 16 years old ...

    Authors: Tianyan Hu, Bélène Podmore, Rosemarie Barnett, Dominik Beier, Wolfgang Galetzka, Nawab Qizilbash, Dennis Haeckl, Jessica Weaver, Timo Boellinger, Sarah Mihm and Tanaz Petigara
    Citation: BMC Pediatrics 2022 22:204
    Content type: Research Published on:

  16. During 2019, neonatal conditions in Ethiopia accounted for 55% of under-5 deaths, with 33 neonatal deaths occurring for every 1000 live births. More than 80% of all newborns deaths are caused by preventable an...

    Authors: Bizuhan Gelaw Birhanu and Johanna Mmabojalwa Mathibe-Neke
    Citation: BMC Pediatrics 2022 22:203
    Content type: Research Published on:

  17. This study provides Dutch national norms for the parent-reported Strengths and Difficulties Questionnaire (SDQ) for children aged 3-14 years, and assesses the test performance of the SDQ Total Difficulties Sca...

    Authors: Meinou H. C. Theunissen, Marianne S. de Wolff, Iris Eekhout, Cathelijne L. Mieloo, Lisanne L. Stone and Sijmen A. Reijneveld
    Citation: BMC Pediatrics 2022 22:202
    Content type: Research Published on:

  18. Innate lymphoid cell (ILC) dysfunction is involved in numerous immune diseases, but this has not been demonstrated in Henoch-Schonlein purpura (HSP). This study aimed to investigate whether ILC dysfunction or ...

    Authors: Lili Zhang, Qiang Lin, Lijun Jiang, Mingfu Wu, Linlin Huang, Wei Quan and Xiaozhong Li
    Citation: BMC Pediatrics 2022 22:201
    Content type: Research Published on:

  19. Bronchopulmonary dysplasia (BPD) is one of the most common adverse consequence of premature delivery and the most common chronic lung disease in infants. BPD is associated with long-term lung diseases and neur...

    Authors: Tingting Yang, Qianqian Shen, Siyu Wang, Tianfang Dong, Liang Liang, Fan Xu, Youfang He, Chunlei Li, Fang Luo, Jiahong Liang, Chunhui Tang and Jinghui Yang
    Citation: BMC Pediatrics 2022 22:200
    Content type: Research Published on:

  20. The study was aimed to assess the prognostic power The Pediatric Risk of Mortality-3 (PRISM-3) and the Pediatric Index of Mortality-3 (PIM-3) to predict in-hospital mortality in a sample of patients admitted t...

    Authors: Zahra Rahmatinejad, Fatemeh Rahmatinejad, Majid Sezavar, Fariba Tohidinezhad, Ameen Abu-Hanna and Saeid Eslami
    Citation: BMC Pediatrics 2022 22:199
    Content type: Research Published on:

  21. Studies have shown that overweight and obesity conditions tend to be stable from childhood and adolescence to adulthood. Unfortunately, little is known about the evolution of abdominal obesity during childhood...

    Authors: Honorato Ortiz-Marrón, Maira Alejandra Ortiz-Pinto, Gloria Cabañas Pujadas, José Galo Martínez Mosquera, Marien Lorente Miñarro, Francisca Menchero Pinos, María Ordobás Gavín and Iñaki Galán
    Citation: BMC Pediatrics 2022 22:198
    Content type: Research Published on:

  22. Chorioamnionitis (CA) affects up to 3.9% of all deliveries worldwide and is one of the leading causes of early-onset neonatal sepsis. Fever≥380C is an essential criterion for the diagnosis of clinical CA. Obstetr...

    Authors: Anvar Paraparambil Vellamgot, Khalil Salameh, Lina Hussain M. Habboub, Rajesh Pattuvalappil, Naser Abulgasim Elkabir, Yousra Shehada Siam and Hakam Khatib
    Citation: BMC Pediatrics 2022 22:197
    Content type: Research Published on:

  23. The aims of this study were to analyze the relationships between minutes of play (MP) and maturity status, fitness, and hormonal levels and to explain how those measures influence the time of play.

    Authors: Ebrahim Eskandarifard, Hadi Nobari, Filipe Manuel Clemente, Rui Silva, Ana Filipa Silva and Antonio José Figueiredo
    Citation: BMC Pediatrics 2022 22:196
    Content type: Research Published on:

  24. Literature on factors influencing medication adherence within paediatric clinical trials is sparse. The Paracetamol and Ibuprofen in the Primary Prevention of Asthma in Tamariki (PIPPA Tamariki) trial is an op...

    Authors: Eunicia Tan, Karen Hoare, Judith Riley, Kathryn Fernando, Libby Haskell, Christopher JD McKinlay, Stuart R Dalziel and Irene Braithwaite
    Citation: BMC Pediatrics 2022 22:195
    Content type: Research Published on:

  25. Although cochlear implantation (CI) has been performed in Kazakhstan since 2007 little is known about quality of life of patients after CI. The aim of this study was to assess the health-related quality of life (...

    Authors: Ruslan Zhumabayev, Galiya Zhumabayeva, Gulnara Kapanova, Nailya Tulepbekova, Anuar Akhmetzhan and Andrej Grjibovski
    Citation: BMC Pediatrics 2022 22:194
    Content type: Research Published on:

  26. Immunization is among the most cost-effective health interventions to improve child survival. However, many countries in sub-Saharan Africa failed to achieve their national and international coverage targets r...

    Authors: Kalkidan Yibeltal, Sitota Tsegaye, Hasset Zelealem, Walelegn Worku, Meaza Demissie, Alemayehu Worku and Yemane Berhane
    Citation: BMC Pediatrics 2022 22:193
    Content type: Research Published on:

  27. In neonatal patients with necrotizing enterocolitis (NEC) the inflammatory response is mediated by a plurality of different proteins. The proteins olfactomedin 4 (OLFM4) and lysozyme (LYZ) are part of the inte...

    Authors: Sonja Diez, Marcus Renner, Veronika Bahlinger, Arndt Hartmann, Manuel Besendörfer and Hanna Müller
    Citation: BMC Pediatrics 2022 22:192
    Content type: Research Published on:

  28. The purpose of this project was to improve perinatal survival by introducing Moyo Fetal Heart Rate (FHR) Monitor coupled with neonatal resuscitation simulation training.

    Authors: Yuda Munyaw, Joshua Gidabayda, Anita Yeconia, Godfrey Guga, Esto Mduma and Paschal Mdoe
    Citation: BMC Pediatrics 2022 22:191
    Content type: Research Published on:

  29. Growth faltering is commonly encountered in breastfed infants during 4—6 months of age in low socioeconomic communities. The objective of this study was to describe the changes of growth indices with age, timi...

    Authors: K. Sithamparapillai, D. Samaranayake and V. P. Wickramasinghe
    Citation: BMC Pediatrics 2022 22:190
    Content type: Research Published on:

  30. Acute respiratory infections (ARI) are the leading cause of morbidity and mortality in children below 5 years of age.

    Authors: Aparna Mukherjee, K. R. Jat, Rakesh Lodha, Jagdish Prasad Goyal, Javeed Iqbal Bhatt, Rashmi Ranjan Das, Vinod Ratageri, Bhadresh Vyas and S. K. Kabra
    Citation: BMC Pediatrics 2022 22:189
    Content type: Research Published on:

  31. Febrile infants ≤ 90 days old make up a significant proportion of patients seeking care in the emergency department (ED). These infants are vulnerable to serious bacterial infections (SBIs) and early identific...

    Authors: Victoria Shi Rui Tan, Gene Yong-Kwang Ong, Khai Pin Lee, Sashikumar Ganapathy and Shu-Ling Chong
    Citation: BMC Pediatrics 2022 22:188
    Content type: Research Published on:

    The Correction to this article has been published in BMC Pediatrics 2022 22:343

  33. The inconsistent use of antiretroviral therapy can lead to the risk of cross-resistance between drugs. This reduces subsequent antiretroviral drug options. The burden of initial antiretroviral therapy ranges f...

    Authors: Molla Azmeraw, Yinager Workineh, Friehiwot Girma, Amare Kassaw, Gashaw Kerebeh, Abraham Tsedalu, Agimasie Tigabu, Teshale Mengesha, Eleni Dagnaw, Dessie Temesgen, Biruk Beletew, Getenet Dessie and Melsew Dagne
    Citation: BMC Pediatrics 2022 22:186
    Content type: Research Published on:

  34. There is limited data on pediatric ventilator-associated events (PedVAE) in the neonatal intensive care unit (NICU) setting, since the CDC mandated state reporting of these events in January 2019. This study s...

    Authors: Novisi Arthur, Ishminder Kaur and Alison J. Carey
    Citation: BMC Pediatrics 2022 22:185
    Content type: Research Published on:

  36. In North Denmark Region (NDR), the incidence of Eosinophilic Oesophagitis (EoE) among adults has increased following a new biopsy protocol in 2011, whereas data on the incidence of EoE among children is lacking.

    Authors: Martin Hollænder, Jacob Holmen Terkelsen, Frederik Kramme, Kasper Bredal, Kristian Kragholm, Kasper Dalby, Søren Hagstrøm, Dorte Melgaard and Anne Lund Krarup
    Citation: BMC Pediatrics 2022 22:183
    Content type: Research Published on:

  37. Central nervous system (CNS) infection has been an ongoing concern in paediatrics. The FilmArray® Meningoencephalitis (FAME) panel has greater sensitivity in identifying the aetiology of CNS infections. This s...

    Authors: Mirta Acuña, Dona Benadof, Karla Yohannessen, Yennybeth Leiva and Pascal Clement
    Citation: BMC Pediatrics 2022 22:182
    Content type: Research Published on:

  38. X-linked agammaglobulinemia (XLA) is an Inborn Errors of Immunity (IEI) characterized by pan-hypogammaglobulinemia and low numbers of B lymphocytes due to mutations in BTK gene. Usually, XLA patients are not susc...

    Authors: Ronaldo da Silva Francisco Junior, Guilherme Loss de Morais, Joseane Biso de Carvalho, Cristina dos Santos Ferreira, Alexandra Lehmkuhl Gerber, Ana Paula de C Guimarães, Flávia Anisio Amendola, Fernanda Pinto-Mariz, Zilton Farias Meira de Vasconcelos, Ekaterini Simões Goudouris and Ana Tereza Ribeiro de Vasconcelos
    Citation: BMC Pediatrics 2022 22:181
    Content type: Case report Published on:

  40. Bloodstream infections (BSIs) cause significant morbidity and mortality in critically ill children but treatment duration is understudied. We describe the durations of antimicrobial treatment that critically i...

    Authors: Sandra Pong, Robert A. Fowler, Srinivas Murthy, Jeffrey M. Pernica, Elaine Gilfoyle, Patricia Fontela, Asgar H. Rishu, Nicholas Mitsakakis, James S. Hutchison, Michelle Science, Winnie Seto, Philippe Jouvet and Nick Daneman
    Citation: BMC Pediatrics 2022 22:179
    Content type: Research Published on:

  42. Mental health in adolescence is an increasing global public health concern. Over half of all mental disorders debut by 14 years of age and remain largely untreated up to adulthood, underlining the significance...

    Authors: Kristina Carlén, Sakari Suominen, Lilly Augustine, Maiju M. Saarinen, Minna Aromaa, Päivi Rautava, André Sourander and Matti Sillanpää
    Citation: BMC Pediatrics 2022 22:177
    Content type: Research Published on:

  43. Invasive bacterial infections (IBI) in children present a difficult clinical challenge. They are often life-threatening, however in the early stages they can be hard to differentiate from benign viral infectio...

    Authors: Michael Paul Corr, Derek Fairley, James P. McKenna, Michael D. Shields and Thomas Waterfield
    Citation: BMC Pediatrics 2022 22:176
    Content type: Research Published on:

  45. Although many studies have described an increased risk of necrotizing enterocolitis in duct dependent congenital heart diseases, very few have investigated its occurrence in full-term infants with duct depende...

    Authors: Gwang-Jun Choi, Jinyoung Song, Hanna Kim, June Huh, I-Seok Kang, Yun Sil Chang, Se In Sung and Myung Chul Hyun
    Citation: BMC Pediatrics 2022 22:174
    Content type: Research Published on:

  46. There is significant variability in clinical pathways available in the diagnostic assessment of ASD, including the order and timing of allied health assessments in relation to paediatrician consultations. Alli...

    Authors: Thuy T. Frakking, John Waugh, Christopher Carty, Alison Burmeister, Annabelle Marozza, Sue Hobbins, Michelle Kilah, Michael David, Lisa Kane, Susan McCormick and Hannah E. Carter
    Citation: BMC Pediatrics 2022 22:173
    Content type: Study protocol Published on:

  47. Understanding of the role of children in COVID-19 transmission has significant implications for school and childcare policies, as well as appropriate targeting of vaccine campaigns. The objective of this syste...

    Authors: Sarah L Silverberg, Bei Yuan Zhang, Shu Nan Jessica Li, Conrad Burgert, Hennady P Shulha, Vanessa Kitchin, Laura Sauvé and Manish Sadarangani
    Citation: BMC Pediatrics 2022 22:172
    Content type: Research Published on:

  48. Early puberty increases risk of adverse health conditions throughout the life course. US girls are experiencing earlier puberty without clear reasons. Studies suggest early life factors, such as infant growth,...

    Authors: Sara Aghaee, Charles P. Quesenberry Jr, Julianna Deardorff, Lawrence H. Kushi, Louise C. Greenspan, Assiamira Ferrara and Ai Kubo
    Citation: BMC Pediatrics 2022 22:171
    Content type: Research Published on:

  49. Pneumonia is the leading cause of mortality in pediatric population. The etiology of pneumonia in this population is variable and changes according to age and disease severity and where the study is conducted....

    Authors: Zulma Vanessa Rueda, Yudy Aguilar, María Angélica Maya, Lucelly López, Andrea Restrepo, Carlos Garcés, Olga Morales, Claudia Roya-Pabón, Mónica Trujillo, Catalina Arango, Ángela Rocio Copete, Cristian Vera, Margarita Rosa Giraldo, Mariana Herrera and Lázaro A. Vélez
    Citation: BMC Pediatrics 2022 22:169
    Content type: Research Published on:

  50. Tenofovir disoproxil fumarate (TDF) is effectively used as the first-line antiviral for chronic hepatitis B virus (HBV) infection in adults and children older than 12 years. To date, no confirmed case of virol...

    Authors: Chien-Yu Chen, Christina Hajinicolaou, Priya Walabh, Luicer Anne Olubayo Ingasia, Ernest Song and Anna Kramvis
    Citation: BMC Pediatrics 2022 22:168
    Content type: Case report Published on:
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BMC Pediatrics

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