PrincipiN ES. Biomarkers in pediatric community-acquired pneumonia. Int J Mol Sci. 2017;18:447.
Article
PubMed Central
Google Scholar
Lee JY, Hwang SJ, Shim JW, Jung HL, Park MS, Woo HY, Shim JY. Clinical significance of serum procalcitonin in patients with community-acquired lobar pneumonia. Korean J Lab Med. 2010;30:406–13.
PubMed
Google Scholar
Hoshina T, Nanishi E, Kanno S, Nishio H, Kusuhara K, Hara T. The utility of biomarkers in differentiating bacterial from nonbacterial lower respiratory tract infection in hospitalized children: Difference of the diagnostic performance between acute pneumonia and bronchitis. J Infect Chemother. 2014;10:616–20.
Article
Google Scholar
Jacobs JW, Lund PK, Potts JT Jr, Bell NH, Habener JF. Procalcitonin is a glycoprotein. J BiolChem. 1981;256:2803–7.
CAS
Google Scholar
Reinhart K, Karzai W, Meisner M. Procalcitonin as a marker of the systemic inflammatory response to infection. Intensive Care Med. 2000;26:1193–200.
Article
CAS
PubMed
PubMed Central
Google Scholar
Zhu F, Jiang Z, Li WH, Wei HY, SuGD. Clinical significance of serum procalcitonin level monitoring on early diagnosis of severe pneumonia on children. Eur Rev Med Pharmacol Sci. 2015;19:4300–3.
CAS
PubMed
Google Scholar
Stockmann C, Ampofo K, Killpack J, Williams DJ, Edwards KM, Grijalva CG, et al. Procalcitonin accurately identifies hospitalizedchildren with low risk of bacterial community-acquired pneumonia. J Pediatric Infect Dis Soc. 2018;7:46–53.
Article
PubMed
Google Scholar
SalluhJIF, Souza-Danta VC, Po´vo P. The current status of biomarkers for the diagnosis of nosocomial pneumonias. CurrOpinCrit Care. 2017;23:000–000.
Google Scholar
Mahajan P, Grzybowski M, Chen X, Kannikeswaran N, Stanley R, Singal B, et al. Procalcitonin as a marker of serious bacterial infections in febrile children younger than 3 years old. AcadEmerg Med. 2014;21:171–9.
Google Scholar
Zhu F, Wei H, Li W. Significance of serum procalcitonin levels in differential diagnosis of pediatric pneumonia. Cell BiochemBiophys. 2015;73:619–22.
Article
CAS
Google Scholar
Agnello L, Bellia C, Di Gangi M, Lo Sasso B, Calvaruso L, Bivona G, et al. Utility of serum procalcitonin and C-reactive protein in severity assessment of community-acquired pneumonia in children. Clin Biochem. 2016;49:47–50.
Article
CAS
PubMed
Google Scholar
Toikka P, Irjala K, Juven T, Virkki R, Mertsola J, Leinonen M, Ruuskanen O. Serum procalcitonin, C-reactive protein and interleukin-6 for distinguishing bacterial and viral pneumonia in children. Pediatr Infect Dis J. 2000;19:598–602.
Article
CAS
PubMed
Google Scholar
Luaces-Cubells C, Mintegi S, García-García JJ, Astobiza E, Garrido-Romero R, Velasco-Rodríguez J, Benito J. Procalcitonin to detect invasive bacterial infection in non-toxic-appearing infants with fever without apparent source in the emergency department. Pediatr Infect Dis J. 2012;31:645–7.
Article
PubMed
Google Scholar
Esposito S, Tagliabue C, Picciolli I, Semino M, Sabatini C, Consolo S, et al. Procalcitonin measurements for guiding antibiotic treatment in pediatric pneumonia. Respir Med. 2011;105:1939–45.
Article
PubMed
Google Scholar
Goyal JP, Kumar P, Mukherjee A, Das RR, Bhat JI, Ratageri V, Vyas B, Lodha R, Acute Respiratory Infection Treatment Unit Study Group. Risk Factors for the Development of Pneumonia and Severe Pneumonia in Children. Indian Pediatr. 2021;58(11):1036–9.
Article
PubMed
Google Scholar
Das RR, Satapathy AK, Mukherjee A, Goyal JP, Bhat JI, Ratageri VH, Vyas B, Lodha R, Members of The ATU (Acute Respiratory Infection Treatment Unit) Group. Role of Clinical Criteria and Oxygen Saturation Monitoring in Diagnosis of Childhood Pneumonia in Children Aged 2 to 59 Months. Indian Pediatr. 2021;58(11):1024–9.
Article
PubMed
Google Scholar
Bhat JI, Charoo BA, Mukherjee A, Ahad R, Das RR, Goyal JP, Vyas B, Ratageri VH, Lodha R, Members of The ATU (Acute Respiratory Infection Treatment Unit) Group. Risk of hospitalization in under-five children with community-acquired pneumonia: a multicentric prospective cohort study. Indian Pediatr. 2021;58(11):1019–23.
Article
PubMed
Google Scholar
Revised WHO classification and treatment of pneumonia in children at health facilities: evidence summaries. https://apps.who.int/iris/bitstream/handle/10665/137319/9789241507813_eng.pdf. Accessed 4 Mar 2022
Christ-Crain M, Müller B. Procalcitonin in bacterial infections–hype, hope, more or less? Swiss Med Wkly. 2005;135:451.
CAS
PubMed
Google Scholar
Christ-Crain M, Jaccard-Stolz D, Bingisser R, et al. Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial. Lancet. 2004;363(9409):600–7.
Article
CAS
PubMed
Google Scholar
Giulia B, Luisa A, Concetta S, Bruna LS, Chiara B, Marcello C. Procalcitonin and community-acquired pneumonia (CAP) in children. ClinicaChimica Acta. 2015;451:215–8.
Article
CAS
Google Scholar
Long B, Long D, Koyfman A. Emergency medicine evaluation of community-acquired pneumonia: history, examination, imaging and laboratory assessment, and risk scores. J Emerg Med. 2017;53:642–52.
Article
PubMed
Google Scholar
Korppi M, Remes S, Heiskanen-Kosma T. Serum procalcitonin concentrations in bacterial pneumonia in children: a negative result in primary healthcare settings. Pediatr Pulmonol. 2003;35:56–61.
Article
PubMed
Google Scholar
Baer G, Baumann P, Buettcher M, Heininger U, Berthet G, Schafer J, et al. Procalcitonin guidance to reduce antibiotic treatmentof lower respiratory tract infection in children and adolescents (ProPAED): a randomized controlled trial. PLoS ONE. 2013;8:e68419.
Article
CAS
PubMed
PubMed Central
Google Scholar
Huang DT, Yealy DM, Filbin MR, Brown AM, Chang CH, Doi Y, et al. ProACT Investigators. Procalcitonin-guided use of antibiotics for lower respiratory tract infection. N Engl J Med. 2018;379:236–49.
Article
CAS
PubMed
PubMed Central
Google Scholar
Schuetz P, Wirz Y, Sager R, Christ-Crain M, Stolz D, Tamm M, et al. Procalcitonin to initiate or discontinue antibiotics in acute respiratory tract infections. Cochrane Database Syst Rev. 2017;10:CD007498.
PubMed
Google Scholar
Self WH, Balk RA, Grijalva CG, Williams DJ, Zhu Y, Anderson EJ, et al. Procalcitonin as a marker of etiology in adults hospitalized with community-acquired pneumonia. Clin Infect Dis. 2017;65:183.
Article
CAS
PubMed
Google Scholar
Dudognon D, Levy C, Chalumeau M, Biscardi S, Dommergues MA, Dubos F, et al. Diagnostic Accuracy of Routinely Available Biomarkers to Predict Bacteremia in Children With Community-Acquired Pneumonia: A Secondary Analysis of the GPIP/ACTIV Pneumonia Study in France, 2009–2018. Front Pediatr. 2021;9:684628.
Article
PubMed
PubMed Central
Google Scholar
Don M, Valent F, Korppi M, Falleti E, De Candia A, Fasoli L, et al. Efficacy of serum procalcitonin in evaluating severity of community-acquired pneumonia in childhood. Scand J Infect Dis. 2007;39:129–37.
Article
CAS
PubMed
Google Scholar
Yadav KK, Awasthi S, Takia L, Agarwal J, Agarwal GG. Procalcitonin and C-reactive protein in WHO defined severe and very severe community acquired pneumonia: A hospital based cross-sectional study. Clin Epidemiol Global Health. 2015;3(Suppl 1):S3–9.
Article
Google Scholar
Lee JY, Hwang SJ, Shim JW, Jung HL, Park MS, Woo HY, Shim JY. Clinical significance of serum procalcitonin in patients with community-acquired lobar pneumonia. Korean J Lab Med. 2010;30:406–13.
PubMed
Google Scholar
Fonseca TS, Gendrel D, Ruuskanen O, Nascimento-Carvalho CM. Pleural Effusion Increases Serum Procalcitonin Values in Children with Community-acquired Pneumonia. Pediatr Infect Dis J. 2015;34:914–5.
Article
PubMed
Google Scholar
Chiu CY, Wong KS, Huang JL, Tasi MH, Lin TY, Hsieh SY. Proinflammatory cytokines, fibrinolytic systemenzymes, and biochemical indices in children with infectious para-pneumonic effusions. Pediatr Infect Dis J. 2008;27:699–703.
Article
PubMed
Google Scholar