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  1. Congenital diaphragmatic hernia is a deficiency of the fetal diaphragm resulting in herniation of the abdominal viscera into the thoracic cavity. The best method of respiratory management of congenital diaphra...

    Authors: Sasagu Kimura, Katsuaki Toyoshima, Tomoaki Shimokaze and Rikuo Hoshino

    Citation: BMC Pediatrics 2020 20:365

    Content type: Case report

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  2. Evidence of hand, foot, and mouth disease (HFMD) in neonates is limited. The aim of this study was to evaluate the clinical symptoms, pathogens, possible transmission routes, and prognosis of neonatal HFMD in ...

    Authors: Shanshan Xu, Huajun Li, Peng Qiao, Guofeng Xu, Dongying Zhao, Xiaoyan Lin, Yu Qin, Huiju Yu, Xi Zhang, Wanju Zhang and Lisu Huang

    Citation: BMC Pediatrics 2020 20:364

    Content type: Research article

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  3. There has been much research into how to promote upper-limb skills to achieve functional independence in children with unilateral spastic cerebral palsy (USCP). One researched intervention is the Breathe Magic...

    Authors: Daisy Fancourt, Jaeyoung Wee and Fabianna Lorencatto

    Citation: BMC Pediatrics 2020 20:363

    Content type: Research article

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  5. The objective of this study was to evaluate and compare the validity and accuracy of the Willems, Demirjian and Nolla methods in predicting chronological age in a Spanish ethnicity population.

    Authors: Marta Macarena Paz Cortés, Rosa Rojo, Esther Alía García and Maria Rosa Mourelle Martínez

    Citation: BMC Pediatrics 2020 20:361

    Content type: Research article

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  6. Newborn hearing screening (NHS) can reduce the economic and social burden of hearing impairment. To track the progress of the goal set by the National Program of Action for Child Development (NPACD) and to est...

    Authors: Xuelian Yuan, Kui Deng, Jun Zhu, Liangcheng Xiang, Yongna Yao, Qi Li, Xiaohong Li and Hanmin Liu

    Citation: BMC Pediatrics 2020 20:360

    Content type: Research article

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  7. Vitamin A plays a pivotal role in respiratory infection, accurate estimation of vitamin A status was recommended in planning and implementing interventions. As infections affect serum vitamin A productions, th...

    Authors: Yuanyuan Li, Ziyao Guo, Guangli Zhang, Xiaoyin Tian, Qinyuan Li, Dapeng Chen and Zhengxiu Luo

    Citation: BMC Pediatrics 2020 20:359

    Content type: Research article

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  8. Children with medical complexity (CMC) denotes the profile of a child with diverse acute and chronic conditions, making intensive use of the healthcare services and with special health and social needs. Previo...

    Authors: Neus Carrilero, Albert Dalmau-Bueno and Anna García-Altés

    Citation: BMC Pediatrics 2020 20:358

    Content type: Research article

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  10. In isolated premature thelarche (IPT) girls, bone age (BA) is considered consistent with chronological age. However, some IPT girls confirmed by gonadotropin-releasing hormone (GnRH) stimulation test could sho...

    Authors: Huiping Su, Zhe Su, Lili Pan, Li Wang, Zhongwei Xu, Gang Peng and Xianglei Li

    Citation: BMC Pediatrics 2020 20:356

    Content type: Research article

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  11. Kangaroo Mother Care (KMC) is one of the interventions widely used in low-income countries to manage Low Birth Weight Infants (LBWIs), a global leading cause of neonatal and child mortality. LBWI largely contr...

    Authors: Christina T. Mathias, Solange Mianda and Themba G. Ginindza

    Citation: BMC Pediatrics 2020 20:355

    Content type: Research article

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  12. Currently, as the number of vaccinated children in Poland and throughout Europe is decreasing. Many factors impact on the rate vaccination and parents’ health behaviours may affect the frequency of vaccination...

    Authors: Jolanta Kraśnicka, Elżbieta Krajewska-Kułak, Krystyna Klimaszewska, Mateusz Cybulski, Andrzej Guzowski, Jolanta Lewko, Cecylia Łukaszuk, Krystyna Kowalczuk, Halina Doroszkiewicz, Anna Baranowska, Katarzyna Krajewska-Ferishah, Hanna Rolka and Wojciech Kułak

    Citation: BMC Pediatrics 2020 20:354

    Content type: Research article

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  13. Children have reported that one reason for participating in research is to help their doctor. This is potentially harmful if associated with coercive consent but might be beneficial for recruitment. We aimed t...

    Authors: Malou L. Luchtenberg, Els L. M. Maeckelberghe, Louise Locock and A. A. Eduard Verhagen

    Citation: BMC Pediatrics 2020 20:353

    Content type: Research article

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  14. Phenylketonuria (PKU), which is characterized by a deficiency of phenylalanine hydroxylase activity, is an autosomal recessive disorder of phenylalanine (Phe) metabolism. Newborn screening is the main populati...

    Authors: Mehdi Shokri, Parviz Karimi, Hadis Zamanifar, Fatemeh Kazemi, Gholamreza Badfar and Milad Azami

    Citation: BMC Pediatrics 2020 20:352

    Content type: Research article

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  15. Pediatric acute liver failure is a rare, life-threatening illness. Mushroom poisoning is a rare etiology. For patients with irreversible pediatric acute liver failure, liver transplantation is the ultimate lif...

    Authors: Chun-Feng Yang, Chu-Qiao Sheng, Yu Ao and Yu-Mei Li

    Citation: BMC Pediatrics 2020 20:351

    Content type: Case report

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  16. Vitamin D is an essential element for body health with its supplements generally administered to prevent vitamin D deficiency. Since these supplements are available in domestic settings, vitamin D toxicity may...

    Authors: Fariba Farnaghi, Hossein Hassanian-Moghaddam, Nasim Zamani, Narges Gholami, Latif Gachkar and Maryam Hosseini Yazdi

    Citation: BMC Pediatrics 2020 20:350

    Content type: Research article

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  17. The human foot is shaped throughout all life in a way that is individual for every human being. Footwear fitting in the process of foot development is the issue covered by a limited range of empirical studies....

    Authors: Ewa Puszczalowska-Lizis, Paulina Zarzyczna, Wioletta Mikulakova, Mariusz Migala and Slawomir Jandzis

    Citation: BMC Pediatrics 2020 20:349

    Content type: Research article

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  18. Neurological complications due to reactivation of varicella-zoster virus (VZV) are very uncommon in immunocompetent patients. Generally a vesicular rash is present on one or more dermatomes, preceding or follo...

    Authors: Silvia Ciancia, Antonella Crisafi, Ilaria Fontana, Alessandro De Fanti, Sergio Amarri and Lorenzo Iughetti

    Citation: BMC Pediatrics 2020 20:348

    Content type: Case report

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  19. Testing for HIV at birth has the potential to identify infants infected in utero, and allows for the possibility of beginning treatment immediately after birth; point of care (POC) testing allows rapid return ...

    Authors: Emma Sacks, Philisiwe Khumalo, Bhekisisa Tsabedze, William Montgomery, Nobuhle Mthethwa, Bonisile Nhlabatsi, Thembie Masuku, Jennifer Cohn and Caspian Chouraya

    Citation: BMC Pediatrics 2020 20:347

    Content type: Research article

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  20. Necrotising Enterocolitis (NEC) is a devastating neonatal disease. A temporal association between red cell transfusion and NEC has been recognized and there have been concerns about the effects of feeding duri...

    Authors: Tim Schindler, Kee Thai Yeo, Srinivas Bolisetty, Joanna Michalowski, Alvin Hock Kuan Tan and Kei Lui

    Citation: BMC Pediatrics 2020 20:346

    Content type: Research article

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  23. Advocacy regarding child health policy is a core tenet of pediatrics. Previous research has demonstrated that most pediatric providers believe collective advocacy and political involvement are essential aspect...

    Authors: Aditi Vasan, Polina Krass, Leah Seifu, Talia A. Hitt, Nadir Ijaz, Leonela Villegas, Kathryn Pallegedara, Sindhu Pandurangi, Morgan Congdon, Beth Rezet and Chén C. Kenyon

    Citation: BMC Pediatrics 2020 20:343

    Content type: Research article

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  24. Congenital central hypoventilation syndrome (CCHS) is a rare disease characterized by sleep apnea. Anoxia often occurs soon after birth, and it is important to prevent anoxia-mediated central nervous system co...

    Authors: Tomomi Ogata, Kazuhiro Muramatsu, Kaori Miyana, Hiroshi Ozawa, Motoki Iwasaki and Hirokazu Arakawa

    Citation: BMC Pediatrics 2020 20:342

    Content type: Research article

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  26. Idiopathic or transient neonatal cholestasis (TNC) represents a group of cholestatic disorders with unidentified origin and remains a diagnosis of exclusion. Dysfunction of hepatobiliary transporters mediating...

    Authors: Anna Baghdasaryan, Lisa Ofner-Ziegenfuß, Carolin Lackner, Peter Fickert, Bernhard Resch, Nicholas Mark Morris and Andrea Deutschmann

    Citation: BMC Pediatrics 2020 20:340

    Content type: Case report

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  27. Assessing the early development of children at a population level in educational settings, may be useful for public health and policy decision making. In this study, we evaluated the psychometric properties an...

    Authors: Sabine Georg, Catherin Bosle, Joachim E. Fischer and Freia De Bock

    Citation: BMC Pediatrics 2020 20:339

    Content type: Research article

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  28. Fabry disease is a rare inborn error of metabolism with profound clinical consequences if untreated. It is caused by the deficiency of α galactosidase A enzyme and is the only lysosomal storage disorder with a...

    Authors: Hasani Hewavitharana, Eresha Jasinge, Hiranya Abeysekera and Jithangi Wanigasinghe

    Citation: BMC Pediatrics 2020 20:338

    Content type: Case report

    Published on:

  29. Physical activity plays an important role in the maintenance of health, and it is especially important during childhood. However, the lack of information about differences in physical activity practice and spo...

    Authors: África Peral-Suárez, Esther Cuadrado-Soto, José Miguel Perea, Beatriz Navia, Ana M. López-Sobaler and Rosa M. Ortega

    Citation: BMC Pediatrics 2020 20:337

    Content type: Research article

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  30. Choroid plexus papillomas (CPPs) are rare, usually benign, neoplasms originating in the central nervous system. In this study, we present the first case of a giant airway-obstructing CPP in the pharynx of a ne...

    Authors: Narae Lee, Mi Hye Bae, Young Mi Han, Kyung Hee Park, Jae-Yeon Hwang, Cheong-Soo Hwang, Jin-Choon Lee and Shin Yun Byun

    Citation: BMC Pediatrics 2020 20:336

    Content type: Case report

    Published on:

  31. Severe acute malnutrition affects around 17 million under-five children in the world, of which the highest burden is accounted by Sub-Saharan Africa where Ethiopia is found. Though there are few individual, in...

    Authors: Zebenay Workneh Bitew, Ayinalem Alemu and Teshager Worku

    Citation: BMC Pediatrics 2020 20:335

    Content type: Research article

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  32. Neurally adjusted ventilatory assist (NAVA) is an innovative mode for assisted ventilation that improves patient-ventilator interaction in children. The aim of this study was to assess the effects of patient-v...

    Authors: Giorgia Spinazzola, Roberta Costa, Daniele De Luca, Giovanna Chidini, Giuliano Ferrone, Marco Piastra and Giorgio Conti

    Citation: BMC Pediatrics 2020 20:334

    Content type: Research article

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  34. The aim of this study was to determine, retrospectively, the serum 25OHD and calcium concentrations of screened neonates of mothers at high risk of 25OHD deficiency and examine whether their measurement contri...

    Authors: Sheikh Arif M. Kozgar, Paul Chay and Craig F. Munns

    Citation: BMC Pediatrics 2020 20:332

    Content type: Research article

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  35. Roughly 10% of newborns need help to complete the transition of birth. For these infants, international guidelines recommend supporting them using a 4-step procedure (A to D). Step A is an assessment time, whi...

    Authors: Claire Boithias, Laure Jule, Stephanie Le Foulgoc, Gilles Jourdain and Dan Benhamou

    Citation: BMC Pediatrics 2020 20:331

    Content type: Research article

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  36. Young children with developmental disabilities and delays spend significant amounts of time at home, show decreased participation in home-based activities, and receive home-based early intervention services to...

    Authors: M. A. Khetani, B. M. McManus, E. C. Albrecht, V. C. Kaelin, J. K. Dooling-Litfin and E. A. Scully

    Citation: BMC Pediatrics 2020 20:330

    Content type: Research article

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  37. Mental health problems often arise in childhood and adolescence and can have detrimental effects on people’s quality of life (QoL). Therefore, it is of great importance for clinicians, policymakers and researc...

    Authors: Jochen O. Mierau, Daphne Kann-Weedage, Pieter J. Hoekstra, Lisan Spiegelaar, Danielle E. M. C. Jansen, Karin M. Vermeulen, Sijmen A. Reijneveld, Barbara J. van den Hoofdakker, Erik Buskens, M. Elske van den Akker-van Marle, Carmen D. Dirksen and Annabeth P. Groenman

    Citation: BMC Pediatrics 2020 20:329

    Content type: Research article

    Published on:

  38. Participation in organized sports is associated with higher physical activity (PA) levels in school-aged-children. Yet, little is known about PA determinants in preschool-aged-children. We examined association...

    Authors: Chu Chen, Fanny Sellberg, Viktor H. Ahlqvist, Martin Neovius, Filip Christiansen and Daniel Berglind

    Citation: BMC Pediatrics 2020 20:328

    Content type: Research article

    Published on:

  39. 13q33–q34 microdeletions are rare chromosomal aberrations associated with a high risk of developmental disability, facial dysmorphism, cardiac defects and other malformation of organs. It is necessary to colle...

    Authors: Xue He, Huijun Shen, Haidong Fu, Chunyue Feng, Zhixia Liu, Yanyan Jin and Jianhua Mao

    Citation: BMC Pediatrics 2020 20:327

    Content type: Case report

    Published on:

  40. Dried blood spots (DBS) have been proposed as potentially tool for detecting invasive bacterial diseases.

    Authors: Fabiana C. Pimenta, Benild Moiane, Fernanda C. Lessa, Anne-Kathryn L. Venero, Iaci Moura, Shanda Larson, Sergio Massora, Alberto Chaúque, Nelson Tembe, Helio Mucavele, Jennifer R. Verani, Cynthia G. Whitney, Betuel Sigaúque and Maria G. S. Carvalho

    Citation: BMC Pediatrics 2020 20:326

    Content type: Research article

    Published on:

  41. Many obese children have at least one obese parent, and some of them have one parent who had undergone bariatric surgery (“bariatric families”). The perceptions and attitudes towards child obesity of parents i...

    Authors: Netta Weiss, Nataly Kalamitzky, Hagar Interator, Ronit Lubetzky and Hadar Moran-Lev

    Citation: BMC Pediatrics 2020 20:325

    Content type: Research article

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  42. Lower limb serial casting is commonly used therapeutically in paediatric clinical practice with some evidence to support its efficacy. This systematic review aimed to determine the effects of serial casting in...

    Authors: Nikki Milne, Michelle Miao and Emma Beattie

    Citation: BMC Pediatrics 2020 20:324

    Content type: Research article

    Published on:

  43. With the importance of early childhood development more recognized by the international society, low-cost and cross-culturally comparable measures of early childhood development is in great demand, both in Chi...

    Authors: Jin Zhao, Sally Anne Brinkman, Yunting Zhang, Yingquan Song, Chunling Lu, Mary Eming Young, Yue Zhang, Patrick Ip, Wenjie Shan and Fan Jiang

    Citation: BMC Pediatrics 2020 20:323

    Content type: Research article

    Published on:

  44. More than 50% of newborns with congenital heart disease (CHD) are unrecognized at birth; however, the use of echocardiogram (Echo) for diagnosing CHD in newborns with asymptomatic, non-syndromic cardiac murmur...

    Authors: Shin Ae Yoon, Woi Hyun Hong and Hwa Jin Cho

    Citation: BMC Pediatrics 2020 20:322

    Content type: Research article

    Published on:

  45. The objective of this prospective, multicentre, observational cohort study was to evaluate the association between admission hypothermia and neonatal outcomes in very low-birth weight (VLBW) infants in multipl...

    Authors: Yong-hui Yu, Li Wang, Lei Huang, Li-ling Wang, Xiao-yang Huang, Xiu-fang Fan, Yan-jie Ding, Cheng-yuan Zhang, Qiang Liu, Ai-rong Sun, Yue-hua Zhao, Guo Yao, Cong Li, Xiu-xiang Liu, Jing-cai Wu, Zhen-ying Yang…

    Citation: BMC Pediatrics 2020 20:321

    Content type: Research article

    Published on:

  46. Alveolar capillary dysplasia (ACD) is a rare cause of severe pulmonary hypertension and respiratory failure in neonates. The onset of ACD is usually preceded by a short asymptomatic period. The condition is re...

    Authors: Zuzanna Kozłowska, Zuzanna Owsiańska, Joanna P. Wroblewska, Apolonia Kałużna, Andrzej Marszałek, Yogen Singh, Bartłomiej Mroziński, Qian Liu, Justyna A. Karolak, Paweł Stankiewicz, Gail Deutsch, Marta Szymankiewicz-Bręborowicz and Tomasz Szczapa

    Citation: BMC Pediatrics 2020 20:320

    Content type: Case report

    Published on:

  47. Hyperacusis is a chronic condition commonly defined as a lowered tolerance or increased sensitivity to everyday environmental sounds. It has been viewed as a paediatric disorder which can cause significant imp...

    Authors: Iskra Potgieter, Kathryn Fackrell, Veronica Kennedy, Rosa Crunkhorn and Derek J. Hoare

    Citation: BMC Pediatrics 2020 20:319

    Content type: Research article

    Published on:

  48. The occurrence of multiple endocrine neoplasia type 2B (MEN2B) in Asians is very rare. In particular, patients with intractable constipation as the main clinical manifestation are even rarer. Atypical clinical...

    Authors: Lidan Zhang, Yan Guo, Lei Ye, Wenli Lu, Zhiya Dong, Wei Wang and Yuan Xiao

    Citation: BMC Pediatrics 2020 20:318

    Content type: Case report

    Published on:

  49. PPP3CA gene encodes the catalytic subunit A of a calcium-dependent protein phosphatase called calcineurin. However, two distinct mechanisms in PPP3CA deficiency would cause two clinically different diseases. Gain...

    Authors: Sai Yang, Xiang Shen, Qingyun Kang, Xiaojun Kuang, Zeshu Ning, Shulei Liu, Hongmei Liao, Zhenhua Cao and Liming Yang

    Citation: BMC Pediatrics 2020 20:315

    Content type: Case report

    Published on:

  50. Depression is one of the most prevalent mental health problems among adolescents. Mental health problems might be the result of child abuse considering that their prevalences are increasing simultaneously in I...

    Authors: Meita Dhamayanti, Anindita Noviandhari, Nina Masdiani, Veranita Pandia and Nanan Sekarwana

    Citation: BMC Pediatrics 2020 20:313

    Content type: Research article

    Published on:

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