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  1. Content type: Research article

    There has been a growing interest in the non-skeletal roles of vitamin D particularly its immune-modulatory properties which has been shown to influence the susceptibility and severity to infections. There is ...

    Authors: Imran Hassam, Rodrick Kisenge, Said Aboud and Karim Manji

    Citation: BMC Pediatrics 2019 19:237

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  2. Content type: Research article

    The diagnosis of pertussis in clinical practice continues to be a challenge worldwide as the symptoms are variable. We aimed to determine the prevalence of pertussis in Chinese children irrespective of cough d...

    Authors: Dan-Xia Wu, Qiang Chen, Kai-Hu Yao, Lan Li, Wei Shi, Jiang-Wei Ke, Ai-Min Wu, Peng Huang and Kun-Ling Shen

    Citation: BMC Pediatrics 2019 19:236

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  3. Content type: Research article

    During the first three months of pregnancy, the developing embryo may be susceptible to external and internal factors, which may lead to structural and functional congenital anomalies. The main objective of th...

    Authors: Molla Taye, Mekbeb Afework, Wondwossen Fantaye, Ermias Diro and Alemayehu Worku

    Citation: BMC Pediatrics 2019 19:234

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  4. Content type: Case report

    Thiamine-responsive megaloblastic anemia (TRMA) is a rare autosomal recessive inherited disease characterized by the clinical triad of megaloblastic anemia, sensorineural deafness, and diabetes mellitus. To da...

    Authors: Xin Li, Qing Cheng, Yu Ding, Qun Li, Ruen Yao, Jian Wang and Xiumin Wang

    Citation: BMC Pediatrics 2019 19:233

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  5. Content type: Research article

    Behçet’s disease (BD) is a rare vasculitic disorder affecting all sizes of vessels. Among BD patients, 4 to 25% of patients with diagnosed age younger than 16 years old are defined as juvenile BD (JBD). This s...

    Authors: Ya-Chiao Hu, Yao-Hsu Yang, Yu-Tsan Lin, Li-Chieh Wang, Hsin-Hui Yu, Jyh-Hong Lee and Bor-Luen Chiang

    Citation: BMC Pediatrics 2019 19:232

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  6. Content type: Research article

    Neonatal bloodspot screening (NBS) identifies conditions to offer early intervention and minimize irreversible damage. NBS policies guide a comprehensive system including processes for storage of neonatal drie...

    Authors: Marleen E. Jansen, Lion J. M. van den Bosch, Marjolein J. Hendriks, Mariska M. J. Scheffer, Marie-Louise Heijnen, Conor M. W. Douglas and Carla G. van El

    Citation: BMC Pediatrics 2019 19:230

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  7. Content type: Case report

    Manganese is a critical trace element that not only has antioxidant properties, but also is essential for various metabolic pathways and neurotransmitters production. However, it can be toxic at high levels, p...

    Authors: Azita Tavasoli, Khadije Arjmandi Rafsanjani, Saba Hemmati, Marziyeh Mojbafan, Elham Zarei and Soudabeh Hosseini

    Citation: BMC Pediatrics 2019 19:229

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  8. Content type: Case report

    Scurvy is one of the oldest diseases known to mankind. Although presently rare in the developed world, scurvy was a common potentially fatal disease. In recent times, the most common risk factors for scurvy in...

    Authors: Robin M. Lund, Mara L. Becker, Steven Shapiro, Tyler Allison and Julia G. Harris

    Citation: BMC Pediatrics 2019 19:228

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  9. Content type: Study protocol

    Premature birth is a growing and serious public health problem affecting more than one of every ten infants worldwide. Bronchopulmonary dysplasia (BPD) is the most common neonatal morbidity associated with pre...

    Authors: Gaston Ofman, Mauricio T. Caballero, Damian Alvarez Paggi, Jacqui Marzec, Florencia Nowogrodzki, Hye-Youn Cho, Mariana Sorgetti, Guillermo Colantonio, Alejandra Bianchi, Luis M. Prudent, Nestor Vain, Gonzalo Mariani, Jorge Digregorio, Elba Lopez Turconi, Cristina Osio, Fernanda Galletti…

    Citation: BMC Pediatrics 2019 19:227

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  10. Content type: Study protocol

    Sub-Saharan Africa (SSA) alone has nine out of every 10 children living with HIV globally and monitoring in this setting remains suboptimal, even as these children grow older. With scalability of antiretrovira...

    Authors: Joseph Fokam, Maria Mercedes Santoro, Desire Takou, Anne-Esther Njom-Nlend, Paul Koki Ndombo, Nelly Kamgaing, Cedric Kamta, Andre Essiane, Samuel Martin Sosso, Alexis Ndjolo, Vittorio Colizzi and Carlo-Federico Perno

    Citation: BMC Pediatrics 2019 19:226

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  11. Content type: Research article

    The prevalence of pediatric allergic diseases has increased rapidly in the United States over the past few decades. Recent studies suggest an association between the increase in allergic disease and early dist...

    Authors: Jeffrey Ni, Hannah Friedman, Bridget C. Boyd, Andrew McGurn, Piotr Babinski, Talar Markossian and Lara R. Dugas

    Citation: BMC Pediatrics 2019 19:225

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  12. Content type: Study protocol

    Responsive parenting interventions that shape parenting behaviors in the areas of sleep and soothing, appropriate and responsive feeding, and routines represent a promising approach to early obesity prevention...

    Authors: Justin A. Lavner, Brian K. Stansfield, Steven R. H. Beach, Gene H. Brody and Leann L. Birch

    Citation: BMC Pediatrics 2019 19:224

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  13. Content type: Research article

    We have limited information on families’ experiences during transition and after discharge from the neonatal intensive care unit.

    Authors: Ashwini Lakshmanan, Katrina Kubicek, Roberta Williams, Marisela Robles, Douglas L. Vanderbilt, Christine B. Mirzaian, Philippe S. Friedlich and Michele Kipke

    Citation: BMC Pediatrics 2019 19:223

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  14. Content type: Correction

    Following publication of the original article [1], the authors opted to revise the first paragraph of the section “Characteristics associated with maternal drinking in pregnancy”. Below is the updated version.

    Authors: Delyse Hutchinson, George J. Youssef, Clare McCormack, Judy Wilson, Steve Allsop, Jake Najman, Elizabeth Elliott, Lucinda Burns, Sue Jacobs, Ingrid Honan, Larissa Rossen, Hannah Fiedler, Samantha Teague, Joanne Ryan, Craig A. Olsson and Richard P. Mattick

    Citation: BMC Pediatrics 2019 19:222

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    The original article was published in BMC Pediatrics 2019 19:149

  15. Content type: Case report

    Cyanosis is usually associated with serious conditions requiring urgent treatment in the neonatal intensive care unit (NICU). Hemoglobin M (Hb M) disease is one type of congenital methemoglobinemia characteriz...

    Authors: Chungwoo Shin, Mee Hong, Myungshin Kim and Jung Hyun Lee

    Citation: BMC Pediatrics 2019 19:221

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  16. Content type: Research article

    Seeking healthcare in children is unique since parents decide upon the type and frequency of healthcare services accessed. Mothers/caregivers lower healthcare seeking behavior is one of the major reason for in...

    Authors: Nebiat Teshager Abegaz, Hailemariam Berhe and Gebremedhin Beedemariam Gebretekle

    Citation: BMC Pediatrics 2019 19:220

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  17. Content type: Research article

    Serious bacterial infections (SBI) are a significant cause of mortality worldwide. Parental concern and clinician’s gut feeling that there is something wrong has been associated with increased likelihood of de...

    Authors: Urzula Nora Urbane, Dita Gaidule-Logina, Dace Gardovska and Jana Pavare

    Citation: BMC Pediatrics 2019 19:219

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  18. Content type: Research article

    Payer-type (government-sponsored health coverage versus private health insurance) has been shown to influence a variety of cardiovascular disease outcomes in adults. However, it is unclear if the payer-type im...

    Authors: Jacob C. Hartz, Elizabeth Yellen, Annette Baker, Justin Zachariah, Heather Ryan, S. Skylar Griggs, Nirav K Desai, Ravi Yanumula, Samuel Vinci, Caroline Brantley, Jennifer Bachman, Ellen McAuliffe, Kimberlee Gauvreau, Michael Mendelson and Sarah de Ferranti

    Citation: BMC Pediatrics 2019 19:217

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  19. Content type: Case report

    Propranolol hydrochloride is the first-line agent recommended for the treatment of infantile hemangiomas (IH). Serious adverse effects of propranolol therapy for hemangiomas are infrequent.

    Authors: Ilirjana Bakalli, Elmira Kola, Robert Lluka, Ermela Celaj, Durim Sala, Inva Gjeta, Sashenka Sallabanda and Dea Klironomi

    Citation: BMC Pediatrics 2019 19:216

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  20. Content type: Research article

    Parents of children with chronic illness have reported decreased psychological and physical quality of life (QoL) relative to parents of children without such illness, which may be associated with the extent o...

    Authors: Alana Fairfax, Jamie Brehaut, Ian Colman, Lindsey Sikora, Alessia Kazakova, Pranesh Chakraborty and Beth K. Potter

    Citation: BMC Pediatrics 2019 19:215

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  21. Content type: Research article

    Globally, in every three preschool children one is affected by malnutrition. In Ethiopia, child undernutrition continues to be a serious public health problem. Data are scarce, especially in 24-59 months age c...

    Authors: Aweke Girma, Haile Woldie, Fantahun Ayenew Mekonnen, Kedir Abdela Gonete and Mekonnen Sisay

    Citation: BMC Pediatrics 2019 19:214

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  22. Content type: Research article

    Anemia is not only a major public health problem among children in developing countries, it is also an important predictor for their future growth and development. The objective of this study was to identify p...

    Authors: Abu Yusuf, A. S. M. A. Mamun, Md. Kamruzzaman, Aik Saw, Nagah M. Abo El-fetoh, Pete E. Lestrel and Golam Hussain

    Citation: BMC Pediatrics 2019 19:213

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  23. Content type: Research article

    It has been established that genetic factors play a substantial role in the development of neonatal hyperbilirubinemia. The population of Indonesia and other Southeast Asian countries has similar, yet differen...

    Authors: Radhian Amandito, Rinawati Rohsiswatmo, Michelle Halim, Vanessa Tirtatjahja and Amarila Malik

    Citation: BMC Pediatrics 2019 19:212

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  24. Content type: Research article

    Intussusception is a gastrointestinal condition in which early treatment is critical. Although its epidemiology and comorbidities have been studied, few studies have included the entire pediatric population of...

    Authors: Soojin Jo, In Seok Lim, Soo Ahn Chae, Sin Weon Yun, Na Mi Lee, Su Yeong Kim and Dae Yong Yi

    Citation: BMC Pediatrics 2019 19:211

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  25. Content type: Study protocol

    Perinatal asphyxia and resulting hypoxic-ischemic encephalopathy is a major cause of death and long-term disability in term born neonates. Up to 20,000 infants each year are affected by HIE in Europe and even ...

    Authors: Christian A. Maiwald, Kim V. Annink, Mario Rüdiger, Manon J. N. L. Benders, Frank van Bel, Karel Allegaert, Gunnar Naulaers, Dirk Bassler, Katrin Klebermaß-Schrehof, Maximo Vento, Hercilia Guimarães, Tom Stiris, Luigi Cattarossi, Marjo Metsäranta, Sampsa Vanhatalo, Jan Mazela…

    Citation: BMC Pediatrics 2019 19:210

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  26. Content type: Research article

    The aim of this study was to investigate attitudes towards embryo donation and embryo donation families among professionals working in primary child healthcare, and their experiences of these families.

    Authors: Gabriela Armuand, Gunilla Sydsjö, Agneta Skoog Svanberg and Claudia Lampic

    Citation: BMC Pediatrics 2019 19:209

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  27. Content type: Research article

    Familial hypercholesterolemia (FH), the most frequent monogenetic hereditary disorder, is underdiagnosed and undertreated. Early identification of FH is essential because of the increased risk for premature ca...

    Authors: Alexandra Kreissl, Nina Walleczek, Pinky Rose Espina, Ulrike Hallwirth and Susanne Greber-Platzer

    Citation: BMC Pediatrics 2019 19:208

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  28. Content type: Research article

    Undernutrition among school age children has an impact on their health, cognition, and educational achievement. Therefore, this study aimed to assess the prevalence and associated factors of stunting and wasti...

    Authors: Zegeye Getaneh, Mulugeta Melku, Mekuanint Geta, Tadele Melak and Melkamu Tamir Hunegnaw

    Citation: BMC Pediatrics 2019 19:207

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  29. Content type: Case report

    Gorham-Stout disease is a rare condition characterized by unifocal and massive type IV osteolysis (variant of idiopathic nonhereditary osteolytic disease) with a slow progression, which is self-limiting for so...

    Authors: Mario Edgar Tena-Sanabria, Larisa Yarindy Jesús-Mejenes, Gabriela Fuentes-Herrera, Félix Alejandro Álvarez-Martínez, Nora Patricia Victorio-García and Juan Carlos Núñez-Enríquez

    Citation: BMC Pediatrics 2019 19:206

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  30. Content type: Research article

    Culture tests have demonstrated that once-daily administration of amoxicillin may be effective in the treatment of group A streptococcal (GAS) pharyngitis. However, culture methods do not allow accurate assess...

    Authors: Akihiro Nakao, Ken Hisata, Makoto Fujimori, Nobuaki Matsunaga, Mitsutaka Komatsu and Toshiaki Shimizu

    Citation: BMC Pediatrics 2019 19:205

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  31. Content type: Research article

    Pediatric ARDS still represents a difficult challenge in Pediatric Intensive Care Units (PICU). Among different treatments proposed, exogenous surfactant showed conflicting results. Aim of this multicenter ret...

    Authors: Andrea Wolfler, Marco Piastra, Angela Amigoni, Pierantonio Santuz, Eloisa Gitto, Emanuele Rossetti, Carmine Tinelli, Cinzia Montani, Fabio Savron, Simone Pizzi, Luigia D’amato, Maria Cristina Mondardini, Giorgio Conti and Annalisa De Silvestri

    Citation: BMC Pediatrics 2019 19:203

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  32. Content type: Case report

    The authors report a 1 month follow up of a neonate described as “miracle baby” because she was born Ebola virus disease-free and survived after her mother was infected with Ebola virus during the third trimes...

    Authors: N. Kasereka Baraka, Mupenzi Mumbere and Evie Ndombe

    Citation: BMC Pediatrics 2019 19:202

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  33. Content type: Research article

    Musculoskeletal pain in youth is common but little is known about the influence of the number of pain sites on pain characteristics. The objective of this study was to compare pain characteristics, quality of ...

    Authors: David M. Bazett-Jones, Michael S. Rathleff and Sinead Holden

    Citation: BMC Pediatrics 2019 19:201

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  34. Content type: Case report

    Noma is a rare disease, which is characterized by rapid progression and a high rate of mortality; however, relatively few cases of noma infection accompanied by septic shock in children have been described. Fu...

    Authors: Lili Xu, Wanrui Wei, Xiaohua Ge, Sibei Wan, Jing Yu and Xiaodong Zhu

    Citation: BMC Pediatrics 2019 19:200

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  35. Content type: Case report

    Tetrahydrobiopterin (BH4) deficiencies are disorders affecting phenylalanine homeostasis, and catecholamine and serotonin biosynthesis. GTP-Cyclohydrolase I deficiency (OMIM 600225) is an extremely rare variant o...

    Authors: Kavinda Chandimal Dayasiri, Nayani Suraweera, Deepal Nawarathne, U. E. Senanayake, B. K. T. P. Dayanath, Eresha Jasinge and Kumudu Weerasekara

    Citation: BMC Pediatrics 2019 19:199

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  36. Content type: Research article

    Childhood vaccinations have been shown to be effective in protecting children against vaccine-preventable diseases. The systematic investigation of the causes of incomplete immunization is critical for the ful...

    Authors: Alemayehu Gonie Mekonnen, Alebachew Demelash Bayleyegn and Esubalew Tesfahun Ayele

    Citation: BMC Pediatrics 2019 19:198

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  37. Content type: Study protocol

    Propionic acidemia (PA) and methylmalonic acidemia (MMA) are rare autosomal recessive inborn errors of metabolism characterized by hyperammonemia due to N-acetylglutamate synthase (NAGS) dysfunction. Carglumic...

    Authors: Marwan Nashabat, Abdulrahman Obaid, Fuad Al Mutairi, Mohammed Saleh, Mohammed Elamin, Hind Ahmed, Faroug Ababneh, Wafaa Eyaid, Abdulrahman Alswaid, Lina Alohali, Eissa Faqeih, Majed Aljeraisy, Mohamed A. Hussein, Ali Alasmari and Majid Alfadhel

    Citation: BMC Pediatrics 2019 19:195

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  38. Content type: Research article

    The short-term effects of particulate matter (PM) exposure on childhood asthma exacerbation and disease control rate is not thoroughly assessed in Chinese population yet. The previous toxic effects of PM expos...

    Authors: Jinzhun Wu, Taoling Zhong, Yu Zhu, Dandan Ge, Xiaoliang Lin and Qiyuan Li

    Citation: BMC Pediatrics 2019 19:194

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  39. Content type: Research article

    Rotavirus antigenemia and RNAemia (the presence of rotavirus RNA in serum) have been commonly identified among paediatric patients with acute gastroenteritis. In this study we examined the association between ...

    Authors: Maria Cleonice A. Justino, Erika A. Campos, Joana D’arc P. Mascarenhas, Luana S. Soares, Sylvia de Fátima S. Guerra, Ismari P. Furlaneto, Manoel Jaime C. Pavão Jr, Tassio S. Maciel, Fredison P. Farias, Orvácio M. Bezerra, Caio Breno G. Vinente, Rodrigo José S. Barros and Alexandre C. Linhares

    Citation: BMC Pediatrics 2019 19:193

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  40. Content type: Research article

    In response to multiple United Kingdom investigations and inquiries into the care of adults with learning disabilities, Mencap produced the Getting it Right Charter which campaigned for the appointment of a Le...

    Authors: Kate Oulton, Jo Wray, Angela Hassiotis, Charlotte Kenten, Jessica Russell, Irene Tuffrey-Wijne, Mark Whiting and Faith Gibson

    Citation: BMC Pediatrics 2019 19:192

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  41. Content type: Research article

    The diagnosis of cow’s milk protein allergy(CMPA) may be easily misdiagnosed due to its lack of specific symptoms. Thus, experts have proposed the use of Cow’s milk-related symptom scores (CoMiSS) to predict C...

    Authors: Yongmei Zeng, Jiyong Zhang, Guoqing Dong, Peihui Liu, Fei Xiao, Weiyan Li, Liting Wang and Qianzhen Wu

    Citation: BMC Pediatrics 2019 19:191

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  42. Content type: Study protocol

    One in three Head Start children is either overweight or obese. We will test the efficacy of an early childhood obesity prevention program, “¡Míranos! Look at Us, We Are Healthy!” (¡Míranos!), which promotes heal...

    Authors: Zenong Yin, Sarah L. Ullevig, Erica Sosa, Yuanyuan Liang, Todd Olmstead, Jeffrey T. Howard, Vanessa L. Errisuriz, Vanessa M. Estrada, Cristina E. Martinez, Meizi He, Sharon Small, Cindy Schoenmakers and Deborah Parra-Medina

    Citation: BMC Pediatrics 2019 19:190

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  43. Content type: Research article

    In Indonesia, the burden of severe hyperbilirubinemia is higher compared to other countries. Whether this is related to ineffective phototherapy (PT) is unknown. The aim of this study is to investigate the per...

    Authors: Mahendra T. A. Sampurna, Kinanti A. Ratnasari, Darto Saharso, Arend F. Bos, Pieter J. J. Sauer, Peter H. Dijk and Christian V. Hulzebos

    Citation: BMC Pediatrics 2019 19:188

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  44. Content type: Research article

    Despite the fact that several scabies outbreaks emerged in schools in Saudi Arabia in 2018, no study has investigated the risk of scabies recurrence among children in Saudi Arabia. This study aimed to estimate...

    Authors: Anwar E. Ahmed, Hoda Jradi, Doaa A. AlBuraikan, Bashayr I. ALMuqbil, Monirah A. Albaijan, Ali M. Al-Shehri and Hamdan AL-Jahdali

    Citation: BMC Pediatrics 2019 19:187

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  45. Content type: Research article

    Probiotic therapy can reduce the incidence of NEC. Therapeutic use of probiotics after NEC diagnosis reduces the severity of NEC in preterm infants or full-term infants is unclear. To evaluate the effect of pr...

    Authors: Zheng-Li Wang, Li Liu, Xiao-Yu Hu, Lu Guo, Qiu-Yu Li, Yao An, Ya-Jun Jiang, Shi Chen, Xue-Qiu Wang, Yu He and Lu-Quan Li

    Citation: BMC Pediatrics 2019 19:185

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