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  2. Study protocol

    Individual contextual factors in the validation of the Bernese pain scale for neonates: protocol for a prospective observational study

    The Bernese Pain Scale for Neonates (BPSN) is a multidimensional pain assessment tool that is already widely used in clinical settings in the German speaking areas of Europe. Recent findings indicate that pain...

    Eva Cignacco, Karin Schenk, Bonnie Stevens, Liliane Stoffel, Dirk Bassler, Sven Schulzke and Mathias Nelle

    BMC Pediatrics 2017 17:171

    Published on: 19 July 2017

  4. Case report

    My child cannot breathe while sleeping: a report of three cases and review

    Sudden breath-holding episodes during sleep in young children are potentially related to sudden infant death syndrome and other life-threatening events. Additionally, these episodes can negatively affect child...

    Won Hee Seo, Minkyu Park, So-Hee Eun, Seonkyeong Rhie, Dae Jin Song and Kyu-Young Chae

    BMC Pediatrics 2017 17:169

    Published on: 18 July 2017

  5. Research article

    Impact of a nurse led telephone intervention on satisfaction and health outcomes of children with inflammatory rheumatic diseases and their families: a crossover randomized clinical trial

    Children suffering from rheumatic disease are faced with multidimensional challenges that affect their quality of life and family dynamics. Symptom management and monitoring of the course of the disease over t...

    Anne-Sylvie Ramelet, Béatrice Fonjallaz, Laura Rio, Sandra Zoni, Pierluigi Ballabeni, Joachim Rapin, Christophe Gueniat and Michaël Hofer

    BMC Pediatrics 2017 17:168

    Published on: 17 July 2017

  6. Study protocol

    Prediction of Extubation readiness in extremely preterm infants by the automated analysis of cardiorespiratory behavior: study protocol

    Extremely preterm infants (≤ 28 weeks gestation) commonly require endotracheal intubation and mechanical ventilation (MV) to maintain adequate oxygenation and gas exchange. Given that MV is independently assoc...

    Wissam Shalish, Lara J. Kanbar, Smita Rao, Carlos A. Robles-Rubio, Lajos Kovacs, Sanjay Chawla, Martin Keszler, Doina Precup, Karen Brown, Robert E. Kearney and Guilherme M. Sant’Anna

    BMC Pediatrics 2017 17:167

    Published on: 17 July 2017

  7. Research article

    Changes in hepatitis B virus antibody titers over time among children: a single center study from 2012 to 2015 in an urban of South Korea

    Hepatitis B virus (HBV) infection is the most common cause of liver disease in endemic areas such as South Korea. After HBV vaccination, hepatitis B surface antibody (HBsAb) titers gradually decrease. Trends i...

    Kyeong Hun Lee, Kyu Seok Shim, In Seok Lim, Soo Ahn Chae, Sin Weon Yun, Na Mi Lee, Young Bae Choi and Dae Yong Yi

    BMC Pediatrics 2017 17:164

    Published on: 14 July 2017

  8. Research article

    Comparing very low birth weight versus very low gestation cohort methods for outcome analysis of high risk preterm infants

    Compared to very low gestational age (<32 weeks, VLGA) cohorts, very low birth weight (<1500 g; VLBW) cohorts are more prone to selection bias toward small-for-gestational age (SGA) infants, which may impact u...

    Louise IM Koller-Smith, Prakesh S. Shah, Xiang Y. Ye, Gunnar Sjörs, Yueping A. Wang, Sharon S. W. Chow, Brian A. Darlow, Shoo K. Lee, Stellan Håkanson and Kei Lui

    BMC Pediatrics 2017 17:166

    Published on: 14 July 2017

  9. Study protocol

    Study protocol: safety and efficacy of propranolol 0.2% eye drops in newborns with a precocious stage of retinopathy of prematurity (DROP-ROP-0.2%): a multicenter, open-label, single arm, phase II trial

    Retinopathy of prematurity (ROP) still represents one of the leading causes of visual impairment in childhood. Systemic propranolol has proven to be effective in reducing ROP progression in preterm newborns, a...

    Luca Filippi, Giacomo Cavallaro, Elettra Berti, Letizia Padrini, Gabriella Araimo, Giulia Regiroli, Valentina Bozzetti, Chiara De Angelis, Paolo Tagliabue, Barbara Tomasini, Giuseppe Buonocore, Massimo Agosti, Angela Bossi, Gaetano Chirico, Salvatore Aversa, Roberta Pasqualetti…

    BMC Pediatrics 2017 17:165

    Published on: 14 July 2017

  10. Research article

    Knowledge and practice of immediate newborn care among health care providers in eastern zone public health facilities, Tigray, Ethiopia, 2016

    According to WHO (2013) report the number of under five-year mortality in Ethiopia was 195,504, out of this 84,437 was from neonatal death and this mortality is related to immediate obstetric and newborn care ...

    Abadi Kidanemariam Berhe, Fitiwi Tinsae and Gebremedhin Gebreegziabher

    BMC Pediatrics 2017 17:157

    Published on: 11 July 2017

  11. Research article

    Screening for glucose-6-phosphate dehydrogenase deficiency in neonates: a comparison between cord and peripheral blood samples

    The use of cord blood in the neonatal screening for glucose-6-phosphate dehydrogenase (G6PD) deficiency is being done with increasing frequency but has yet to be adequately evaluated against the use of periphe...

    Saif AlSaif, Ma. Bella Ponferrada, Khalid AlKhairy, Khalil AlTawil, Adel Sallam, Ibrahim Ahmed, Mohammed Khawaji, Khalid AlHathlol, Beverly Baylon, Ahmed AlSuhaibani and Mohammed AlBalwi

    BMC Pediatrics 2017 17:159

    Published on: 11 July 2017

  12. Research article

    Effectiveness of rotavirus vaccines against hospitalisations in Japan

    In Japan, rotavirus hospitalisation occurs at a rate from 2.8 to 13.7 per 1000 child-years among children age less than 5 years, and it imposes a substantial burden to the healthcare system in the country. Whi...

    Yoshiyuki Fujii, Atsuko Noguchi, Shinobu Miura, Haruka Ishii, Toyoko Nakagomi, Osamu Nakagomi and Tsutomu Takahashi

    BMC Pediatrics 2017 17:156

    Published on: 11 July 2017

  13. Research article

    The role of family and school-level factors in bullying and cyberbullying: a cross-sectional study

    Bullying and cyberbullying are common phenomena in schools. These negative behaviours can have a significant impact on the health and particularly mental health of those involved in such behaviours, both as vi...

    Leonardo Bevilacqua, Nichola Shackleton, Daniel Hale, Elizabeth Allen, Lyndal Bond, Deborah Christie, Diana Elbourne, Natasha Fitzgerald-Yau, Adam Fletcher, Rebecca Jones, Alec Miners, Stephen Scott, Meg Wiggins, Chris Bonell and Russell M. Viner

    BMC Pediatrics 2017 17:160

    Published on: 11 July 2017

  14. Research article

    Transition to parenthood in the neonatal care unit: a qualitative study and conceptual model designed to illuminate parent and professional views of the impact of webcam technology

    Complications during pregnancy, childbirth and/or the postnatal period may result in the admission of a baby to a neonatal unit (NNU). While the survival and long-term prospects of high-risk infants are enhanc...

    Susan Kerr, Caroline King, Rhona Hogg, Kerri McPherson, Janet Hanley, Maggie Brierton and Sean Ainsworth

    BMC Pediatrics 2017 17:158

    Published on: 11 July 2017

  15. Research article

    Descriptive analysis of cochrane child-relevant systematic reviews: an update and comparison between 2009 and 2013

    Systematic reviews support health systems and clinical decision-making by identifying and summarizing all existing studies on a particular topic. In 2009, a comprehensive description of child-relevant systemat...

    Katelynn Crick, Denise Thomson, Ricardo M. Fernandes, Megan Nuspl, Dean T. Eurich, Brian H. Rowe and Lisa Hartling

    BMC Pediatrics 2017 17:155

    Published on: 11 July 2017

  17. Research article

    Early characteristics of infants with pulmonary hypertension in a referral neonatal intensive care unit

    Approximately 8–23% of premature infants develop pulmonary hypertension (PH), and this diagnosis confers a higher possibility of mortality. As a result, professional societies recommend PH screening in prematu...

    Shilpa Vyas-Read, Usama Kanaan, Prabhu Shankar, Jane Stremming, Curtis Travers, David P. Carlton and Anne Fitzpatrick

    BMC Pediatrics 2017 17:163

    Published on: 11 July 2017

  18. Research article

    Using LMS tables to determine waist circumference and waist-to-height ratios in Colombian children and adolescents: the FUPRECOL study

    Waist circumference (WC) and waist-to-height ratio (WHtR) are often used as indices predictive of central obesity. The aims of this study were: 1) to obtain smoothed centile charts and LMS tables for WC and WH...

    Robinson Ramírez-Vélez, Javier Moreno-Jiménez, Jorge Enrique Correa-Bautista, Javier Martínez-Torres, Katherine González-Ruiz, Emilio González-Jiménez, Jacqueline Schmidt-RioValle, Felipe Lobelo and Antonio Garcia-Hermoso

    BMC Pediatrics 2017 17:162

    Published on: 11 July 2017

  19. Study protocol

    Effectiveness of skin-to-skin contact versus care-as-usual in mothers and their full-term infants: study protocol for a parallel-group randomized controlled trial

    Twenty-to-forty percent of women experience postpartum depressive symptoms, which can affect both the mother and infant. In preterm infants, daily skin-to-skin contact (SSC) between the mother and her infant h...

    Kelly H. M. Cooijmans, Roseriet Beijers, Anne C. Rovers and Carolina de Weerth

    BMC Pediatrics 2017 17:154

    Published on: 6 July 2017

  20. Study protocol

    Study protocol: families and childhood transitions study (FACTS) – a longitudinal investigation of the role of the family environment in brain development and risk for mental health disorders in community based children

    Extant research has demonstrated that parenting behaviour can be a significant contributor to the development of brain structure and mental health during adolescence. Nonetheless, there is limited research exa...

    J.G. Simmons, O.S. Schwartz, K. Bray, C. Deane, E. Pozzi, S. Richmond, J. Smith, N. Vijayakumar, M.L. Byrne, M.L. Seal, M.B.H. Yap, N.B. Allen and S.L. Whittle

    BMC Pediatrics 2017 17:153

    Published on: 30 June 2017

  21. Case report

    Intermittent low platelet counts hampering diagnosis of X-linked thrombocytopenia in children: report of two unrelated cases and a novel mutation in the gene coding for the Wiskott-Aldrich syndrome protein

    Thrombocytopenia can occur in different circumstances during childhood and although immune thrombocytopenia is its most frequent cause, it is important to consider other conditions, especially when there is a ...

    Samuel Souza Medina, Lúcia Helena Siqueira, Marina Pereira Colella, Gabriela Goes Yamaguti-Hayakawa, Bruno Kosa Lino Duarte, Maria Marluce Dos Santos Vilela and Margareth Castro Ozelo

    BMC Pediatrics 2017 17:151

    Published on: 22 June 2017

  22. Study protocol

    A multicentre randomised controlled trial of levetiracetam versus phenytoin for convulsive status epilepticus in children (protocol): Convulsive Status Epilepticus Paediatric Trial (ConSEPT) - a PREDICT study

    Convulsive status epilepticus (CSE) is the most common life-threatening childhood neurological emergency. Despite this, there is a lack of high quality evidence supporting medication use after first line benzo...

    Stuart R. Dalziel, Jeremy Furyk, Megan Bonisch, Ed Oakley, Meredith Borland, Jocelyn Neutze, Susan Donath, Cynthia Sharpe, Simon Harvey, Andrew Davidson, Simon Craig, Natalie Phillips, Shane George, Arjun Rao, Nicholas Cheng, Michael Zhang…

    BMC Pediatrics 2017 17:152

    Published on: 22 June 2017

  23. Research article

    Validity and reliability of electroacoustic probe for diagnosis of developmental dysplasia of the hip

    Sound transmission is used in the diagnosis of hip dysplasia since the end of the 80’s. Aim of this study is to quantify the validity and reliability of electroacoustic probe for the diagnosis of hip dysplasia...

    Nicolas Padilla-Raygoza, Georgina Olvera-Villanueva, Silvia del Carmen Delgado-Sandoval, Teodoro Cordova-Fraga, Modesto Antonio Sosa-Aquino and Vicente Beltran-Campos

    BMC Pediatrics 2017 17:149

    Published on: 19 June 2017

  25. Research article

    Validity of a family-centered approach for assessing infants’ social-emotional wellbeing and their developmental context: a prospective cohort study

    Family-centered care seems promising in preventive pediatrics, but evidence is lacking as to whether this type of care is also valid as a means to identify risks to infants’ social-emotional development. We ai...

    Margriet Hielkema, Andrea F. De Winter and Sijmen A. Reijneveld

    BMC Pediatrics 2017 17:148

    Published on: 15 June 2017

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