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  1. Content type: Research article

    Pediatric ulcerative colitis (UC) is typically more extensive and has a more active disease course than adult UC, and requires early treatment augmentation to achieve and maintain disease remission. The presen...

    Authors: Hitoshi Tajiri, Katsuhiro Arai, Seiichi Kagimoto, Reiko Kunisaki, Nobuyuki Hida, Noriko Sato, Hiroshi Yamada, Mieko Nagano, Yutaka Susuta, Kunihiko Ozaki, Kazuoki Kondo and Toshifumi Hibi

    Citation: BMC Pediatrics 2019 19:351

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  2. Content type: Case report

    The symptoms of meningitis which include fever, headache, photophobia and irritability along with abducens nerve palsy pose a diagnostic dilemma requiring urgent attention. Here we report how such a dilemma wa...

    Authors: A. S. Athapathu, E. R. S. Bandara, A. A. H. S. Aruppala, K. M. A. U. Chandrapala and Sachith Mettananda

    Citation: BMC Pediatrics 2019 19:350

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  3. Content type: Case report

    Neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD) is an autosomal recessive disorder and one of the most common inherent causes of cholestatic jaundice in Asian infants. Mutations in the SLC25...

    Authors: Linlin Zhang, Yingying Li, Wenli Shi, Jinshuang Gao, Yuan Tian, Ying Li, Yaqing Guo, Shihong Cui and Xiaoan Zhang

    Citation: BMC Pediatrics 2019 19:348

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  4. Content type: Case report

    DNA ligase IV deficiency is a rare autosomal recessive disorder caused by hypomorphic mutations in the DNA ligase IV (LIG4) gene. DNA ligase IV is an essential protein for the development of a healthy immune s...

    Authors: Sarah Schober, Karin Schilbach, Michaela Doering, Karin M. Cabanillas Stanchi, Ursula Holzer, Patrick Kasteleiner, Jens Schittenhelm, Juergen F. Schaefer, Ingo Mueller, Peter Lang and Rupert Handgretinger

    Citation: BMC Pediatrics 2019 19:346

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  5. Content type: Research article

    Acute respiratory infections (ARIs) are one of the main causes of morbidity and mortality in children. Viruses are the main etiological agents, and their behavior tends to be seasonal and vary by geographical ...

    Authors: Obando Evelyn, Fernández-Sarmiento Jaime, Montoya David, Acevedo Lorena, Arroyave Jenifer and Gamboa Oscar

    Citation: BMC Pediatrics 2019 19:345

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  6. Content type: Case report

    Mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase (mHS) deficiency is an autosomal recessive inborn error of metabolism, which will give rise to failure of ketogenesis in liver during illness or fasting. I...

    Authors: Hao Liu, Jing-kun Miao, Chao-wen Yu, Ke-xing Wan, Juan Zhang, Zhao-jian Yuan, Jing Yang, Dong-juan Wang, Yan Zeng and Lin Zou

    Citation: BMC Pediatrics 2019 19:344

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  7. Content type: Research article

    Musculoskeletal injury, including fracture, is one of the most common causes of morbidity in pediatric patients. The purpose of this epidemiologic study is to determine the prevalence and risk factors for frac...

    Authors: Jared A. Wolfe, Heather Wolfe, Amanda Banaag, Scott Tintle and Tracey Perez Koehlmoos

    Citation: BMC Pediatrics 2019 19:343

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  8. Content type: Research article

    Functional abdominal pain disorders (FAPD) have been widely reported as a major group of gastrointestinal disorders across the world. This study describes the prevalence, related factors, symptomatology and it...

    Authors: Hanifah Oswari, Fatima Safira Alatas, Badriul Hegar, William Cheng, Arnesya Pramadyani, Marc Alexander Benninga and Shaman Rajindrajith

    Citation: BMC Pediatrics 2019 19:342

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  9. Content type: Research article

    Although over the years a number of studies have used chest circumference (CC) as a sensitive tool to identify the health status of infants, a particularly important aspect for this population is the lack of d...

    Authors: Ingrid G. Azevedo, Norrara S. O. Holanda, Nivia M. R. Arrais, Raweny T. G. Santos, Ana G. F. Araujo and Silvana A. Pereira

    Citation: BMC Pediatrics 2019 19:341

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  10. Content type: Research article

    The aim of the current research was to investigate the unplanned readmission rates and identify the risk factors of unplanned readmissions in pediatric general surgical specialties.

    Authors: Chao Zheng, Hong Zhou, Hai Zhu, Bailin Chen, Lin Qiu and Chunbao Guo

    Citation: BMC Pediatrics 2019 19:340

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  11. Content type: Research article

    Although breastfeeding is touted as providing many health benefits to infants, some aspects of this relationship remain poorly understood.

    Authors: Nicole M. Frank, Kristian F. Lynch, Ulla Uusitalo, Jimin Yang, Maria Lönnrot, Suvi M. Virtanen, Heikki Hyöty and Jill M. Norris

    Citation: BMC Pediatrics 2019 19:339

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  12. Content type: Research article

    Earlier pubertal timing has been observed in many countries. We aimed to explore if prenatal exposure to maternal obesity, smoking, and alcohol intake was associated with timing of puberty by use of a novel ma...

    Authors: Nis Brix, Andreas Ernst, Lea Lykke Braskhøj Lauridsen, Erik Thorlund Parner, Onyebuchi A. Arah, Jørn Olsen, Tine Brink Henriksen and Cecilia Høst Ramlau-Hansen

    Citation: BMC Pediatrics 2019 19:338

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  13. Content type: Research article

    An exclusive human milk diet (EHMD) using human milk based products (pre-term formula and fortifiers) has been shown to lead to significant clinical benefits for very low birth weight (VLBW) babies (below 1250...

    Authors: Grace Hampson, Sarah Louise Elin Roberts, Alan Lucas and David Parkin

    Citation: BMC Pediatrics 2019 19:337

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  14. Content type: Research article

    The World Health Organization (WHO) recommends incorporating psychosocial stimulation into the management of severe acute malnutrition (SAM). However, there is little evidence about the effectiveness of these ...

    Authors: Teklu Gemechu Abessa, Berhanu Nigussie Worku, Mekitie Wondafrash, Tsinuel Girma, Johan Valy, Johan Lemmens, Liesbeth Bruckers, Patrick Kolsteren and Marita Granitzer

    Citation: BMC Pediatrics 2019 19:336

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  15. Content type: Research article

    We aimed to study the prevalence of enterovirus (EV) meningitis without the presence of cerebrospinal fluid (CSF) pleocytosis and identify patient factors and clinical features associated with it.

    Authors: Yura Ko, Woochan Jeon, Minjung Kathy Chae, Heewon Yang and Jisook Lee

    Citation: BMC Pediatrics 2019 19:335

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  16. Content type: Study protocol

    Patent ductus arteriosus (PDA), the most commonly diagnosed cardiovascular condition in preterm infants, is associated with increased mortality and harmful long-term outcomes (chronic lung disease, neurodevelo...

    Authors: Jonathan L. Slaughter, Clifford L. Cua, Jennifer L. Notestine, Brian K. Rivera, Laura Marzec, Erinn M. Hade, Nathalie L. Maitre, Mark A. Klebanoff, Megan Ilgenfritz, Vi T. Le, Dennis J. Lewandowski and Carl H. Backes

    Citation: BMC Pediatrics 2019 19:333

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  17. Content type: Research article

    Childhood obesity is often associated with non-alcoholic fatty liver disease (NAFLD), the most common chronic liver disease in pediatrics.

    Authors: Susanne Greber-Platzer, Alexandra Thajer, Svenja Bohn, Annette Brunert, Felicitas Boerner, Wolfgang Siegfried, Andreas Artlich, Anja Moeckel, Hildegunde Waldecker-Krebs, Sophie Pauer and Reinhard W. Holl

    Citation: BMC Pediatrics 2019 19:332

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  18. Content type: Research article

    Esophageal atresia (EA) is a rare congenital malformation, which is characterized by the discontinuity of the esophagus. We investigated the agreement between mothers’, fathers’, and children’s’ ratings on hea...

    Authors: Stefanie Witt, Janika Bloemeke, Monika Bullinger, Jens Dingemann, Michaela Dellenmark-Blom and Julia Quitmann

    Citation: BMC Pediatrics 2019 19:330

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  19. Content type: Research article

    Most studies have revealed that the incidence of morbidity and mortality of preterm male infants is greater than that of preterm female infants. Recently, conflicting outcomes have been reported regarding mixe...

    Authors: Bernard Barzilay, Nina Shirman, Haim Bibi and Ibrahim Abu-Kishk

    Citation: BMC Pediatrics 2019 19:328

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  20. Content type: Research article

    Background: Childhood undernutrition causes significant morbidity and mortality in low- and middle-income countries (LMICs). In Tanzania, the in-hospital prevalence of undernutrition in children under five yea...

    Authors: Prosper J. Bashaka, Hendry R. Sawe, Victor Mwafongo, Juma A. Mfinanga, Michael S. Runyon and Brittany L. Murray

    Citation: BMC Pediatrics 2019 19:327

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  21. Content type: Study protocol

    Congenital heart disease (CHD) is the most prevalent congenital malformation affecting 1 in 100 newborns. While advances in early diagnosis and postnatal management have increased survival in CHD children, wor...

    Authors: I. Ribera, A. Ruiz, O. Sánchez, E. Eixarch, E. Antolín, E. Gómez-Montes, M. Pérez-Cruz, M. Cruz-Lemini, M. Sanz-Cortés, S. Arévalo, Q. Ferrer, E. Vázquez, L. Vega, P. Dolader, A. Montoliu, H. Boix…

    Citation: BMC Pediatrics 2019 19:326

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  22. Content type: Research article

    Measles (rubeola) is a highly contagious disease with significant morbidity/mortality. Measles-Mumps-Rubella (MMR) is a live-attenuated vaccine used in the United States (US) since the early 1970s to prevent m...

    Authors: David A. Geier, Janet K. Kern and Mark R. Geier

    Citation: BMC Pediatrics 2019 19:325

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  23. Content type: Research article

    A few studies have reported a positive association between phthalate exposure and pubertal timing, but several conflicting reports exist. The main objective of the study was to determine whether phthalate expo...

    Authors: Mo Kyung Jung, Han Saem Choi, Junghwan Suh, Ahreum Kwon, Hyun Wook Chae, Woo Jung Lee, Eun-Gyong Yoo and Ho-Seong Kim

    Citation: BMC Pediatrics 2019 19:323

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  24. Content type: Research article

    Early identification of children with motor difficulties, such as developmental coordination disorder (DCD), is essential. At present only a fraction of children with DCD are identified. The purpose of the stu...

    Authors: P. Asunta, H. Viholainen, T. Ahonen and P. Rintala

    Citation: BMC Pediatrics 2019 19:322

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  25. Content type: Research article

    Few data are currently available for Kawasaki disease (KD) below 12 months especially in Caucasians. This study aims to analyze clinical and laboratory features of KD among an Italian cohort of infants.

    Authors: Greta Mastrangelo, Rolando Cimaz, Giovani Battista Calabri, Gabriele Simonini, Donatella Lasagni, Massimo Resti and Sandra Trapani

    Citation: BMC Pediatrics 2019 19:321

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  26. Content type: Research article

    Sudan falls in the meningitis belt where most global cases of bacterial meningitis are reported. Highly accurate decision support tools have been developed by international specialized societies to guide the d...

    Authors: Nada Abdelghani Abdelrahim, Imad Mohammed Fadl-Elmula and Hassan Mohammed Ali

    Citation: BMC Pediatrics 2019 19:319

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  27. Content type: Research article

    Although aminoglycosides are routinely used in neonates, controversy exists regarding empiric dosing regimens. The objectives were to determine gentamicin pharmacokinetics in neonates, and develop initial mg/k...

    Authors: Monique Bergenwall, Sandra A. N. Walker, Marion Elligsen, Dolores C. Iaboni, Carla Findlater, Winnie Seto and Eugene Ng

    Citation: BMC Pediatrics 2019 19:318

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  28. Content type: Correction

    Following publication of the original article [1], the authors reported that Table 4 was incorrectly presented. The revised and corrected version is shown below.

    Authors: Sara Aghaee, Julianna Deardorff, Louise C. Greenspan, Charles P. Quesenberry Jr, Lawrence H. Kushi and Ai Kubo

    Citation: BMC Pediatrics 2019 19:317

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    The original article was published in BMC Pediatrics 2019 19:277

  29. Content type: Research article

    The study objective was to determine the carriage and serotype distribution of Streptococcus pneumoniae among children in Accra, Ghana, five years after the introduction of the pneumococcal conjugate vaccine (PCV...

    Authors: Nicholas T. K. D. Dayie, Elizabeth Y. Tettey, Mercy J. Newman, Elizabeth Bannerman, Eric S. Donkor, Appiah-Korang Labi and Hans-Christian Slotved

    Citation: BMC Pediatrics 2019 19:316

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  30. Content type: Research article

    Since iron plays an important role in several physiological processes, its deficiency but also overload may harm the development of children. The aim was to assess the effect of iron–fortified milk on the iron...

    Authors: Lucía Iglesias Vázquez, Josefa Canals, Núria Voltas, Cristina Jardí, Carmen Hernández, Cristina Bedmar, Joaquín Escribano, Núria Aranda, Rosa Jiménez, Josep Maria Barroso, Blanca Ribot and Victoria Arija

    Citation: BMC Pediatrics 2019 19:315

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  31. Content type: Research article

    Iron deficiency anemia (IDA) is a global public health issue that affect more than 2 billion individuals worldwide. However evidence for optimal management of IDA is lacking.

    Authors: Hadi J. Al Sulayyim, Ali Al Omari and Motasim Badri

    Citation: BMC Pediatrics 2019 19:314

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  32. Content type: Research article

    Background: Despite several years of guidance on infant feeding, there has been only a slight change in consumer compliance. Therefore, this study aimed to analyse parents feeding practices, explore physicians...

    Authors: Jean-Pierre Chouraqui, Bérénice Delmas, Marine Le Bris, Marc Bellaiche, Camille Jung and Thierry Hanh

    Citation: BMC Pediatrics 2019 19:313

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  33. Content type: Research article

    Earlier age of menarche has been associated with an increased risk of chronic diseases during adulthood, but whether early menarche has intergenerational effect is not clear.

    Authors: Hui Wang, Yunting Zhang, Ying Tian, Fei Li, Chonghui Yan, Hui Wang, Zhongchen Luo, Fan Jiang and Jun Zhang

    Citation: BMC Pediatrics 2019 19:312

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  34. Content type: Research article

    Complications of prematurity are the leading cause of deaths in children under the age of five. The predominant reason for these preterm deaths is respiratory distress syndrome (RDS). In low-income countries (...

    Authors: F. Okello, E. Egiru, J. Ikiror, L. Acom, KSM Loe, P. Olupot-Olupot and K. Burgoine

    Citation: BMC Pediatrics 2019 19:311

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  35. Content type: Research article

    Hypertension in children and adolescents is on the rise worldwide, especially in China. The prevalence of hypertension is related to many factors, such as obesity. In the era of smart phones, it is important t...

    Authors: Yunfei Zou, Ning Xia, Yunqing Zou, Zhen Chen and Yufeng Wen

    Citation: BMC Pediatrics 2019 19:310

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  36. Content type: Research article

    The role of the father as a co-caregiver is becoming increasingly important across cultures. Parental psychological distress is an influencing factor of maladaptive parenting behaviors and negative psychosocia...

    Authors: Hyeon Sik Chu and Hanyi Lee

    Citation: BMC Pediatrics 2019 19:308

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  37. Content type: Research article

    To evaluate relationship between socio-economic environment and overweight in Madrid and Barcelona, adjusting for possible confounding factors.

    Authors: Romana Albaladejo, Rosa Villanueva, Paloma Astasio, Paloma Ortega, Juana Santos and Enrique Regidor

    Citation: BMC Pediatrics 2019 19:307

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  38. Content type: Research article

    Household air pollution from combustion of solid fuels for cooking and space heating is one of the most important risk factors of the global burden of disease. This study was aimed to determine the association...

    Authors: Nayomi Ranathunga, Priyantha Perera, Sumal Nandasena, Nalini Sathiakumar, Anuradhani Kasturiratne and Rajitha Wickremasinghe

    Citation: BMC Pediatrics 2019 19:306

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  39. Content type: Research article

    A Shortage or excessive intake of the nutrient is malnutrition; affecting every aspect of human beings. Malnutrition at childhood has long-lasting and multiple effects. In Ethiopia significant numbers of child...

    Authors: Nigusie Birhan Tebeje, Gashaw Andargie Biks, Solomon Mekonnen Abebe and Melike Endris Yesuf

    Citation: BMC Pediatrics 2019 19:304

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  40. Content type: Technical advance

    Traditional percutaneous device closure of perimembranous ventricular septal defects (PmVSDs) is a minimally invasive technique, but can result in high radiation exposure and can result in potential arterial c...

    Authors: Haisong Bu, Yifeng Yang, Qin Wu, Wancun Jin and Tianli Zhao

    Citation: BMC Pediatrics 2019 19:302

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