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  1. Systemic drug therapy is generally recommended for infant huge vascular anomalies associated with thrombocytopenia and coagulopathy, but some patients are not suitable due to drug unresponsiveness or life thre...

    Authors: Yaohao Wu, Ronglin Qiu, Lexiang Zeng, Liyang Liang, Jie Zhang, Jiajia Zhou, Wenli Jiang, Jianhang Su and Xiaogeng Deng

    Citation: BMC Pediatrics 2020 20:187

    Content type: Research article

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  2. Hydrops fetalis as well as abdominal compartment syndrome (ACS) are conditions that are associated with high mortality rates. A rare case of immature gastric teratoma causing fetal hydrops and subsequent ACS i...

    Authors: Alvin B. Caballes, Leona Bettina P. Dungca, Maria Esterlita V. Uy, Maria Geraldine C. Torralba and Cristina Marie G. Embuscado

    Citation: BMC Pediatrics 2020 20:186

    Content type: Case report

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  3. Infections caused by antibiotic resistant pathogens are increasing, with antibiotic overuse a key contributing factor.

    Authors: Gaston Arnolda, Peter Hibbert, Hsuen P. Ting, Charli Molloy, Louise Wiles, Meagan Warwick, Tom Snelling, Nusrat Homaira, Adam Jaffe and Jeffrey Braithwaite

    Citation: BMC Pediatrics 2020 20:185

    Content type: Research article

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  4. Intussusception decreases blood flow to the bowel, and tissue hypoperfusion results in increased lactic acid levels. We aimed to determine whether lactic acid levels are associated with pediatric intussuscepti...

    Authors: Jeong-Yong Lee, Young-Hoon Byun, Jun-Sung Park, Jong Seung Lee, Jeong-Min Ryu and Seung Jun Choi

    Citation: BMC Pediatrics 2020 20:184

    Content type: Research article

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  5. Mortality among children under 5 years of age admitted to malnutrition units in sub-Saharan Africa remains high. The burden of HIV infection, a major risk factor for mortality among patients with severe acute ...

    Authors: Damalie Nalwanga, Victor Musiime, Samuel Kizito, John Baptist Kiggundu, Anthony Batte, Philippa Musoke and James K. Tumwine

    Citation: BMC Pediatrics 2020 20:182

    Content type: Research article

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  6. Maternal antibodies are key components of the protective responses of infants who are unable to produce their own IgG until 6 months of life. There is evidence that HIV-exposed uninfected children (HEU) have I...

    Authors: Silvia Baroncelli, Clementina Maria Galluzzo, Giuseppe Liotta, Mauro Andreotti, Stefano Orlando, Fausto Ciccacci, Haswell Jere, Richard Luhanga, Jean Baptiste Sagno, Roberta Amici, Maria Cristina Marazzi and Marina Giuliano

    Citation: BMC Pediatrics 2020 20:181

    Content type: Research article

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  7. Severe respiratory distress is a leading cause of mortality among neonates in Malawi. Despite evidence on the safety, cost effectiveness and efficacy of bubble continuous positive airway pressure (CPAP) in man...

    Authors: Sangwani Salimu, Mai-Lei Woo Kinshella, Marianne Vidler, Mwai Banda, Laura Newberry, Queen Dube, Elizabeth M. Molyneux, David M. Goldfarb, Kondwani Kawaza and Alinane Linda Nyondo-Mipando

    Citation: BMC Pediatrics 2020 20:180

    Content type: Research article

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  8. Thyroid hormones play an important role in the normal growth and maturation of the central nervous system. However, few publications addressed the altered thyroid hormone levels in preterm small for gestationa...

    Authors: Chunhua Liu, Kaiyan Wang, Jizhong Guo, Jiru Chen, Mei Chen, Zhexi Xie, Pu Chen, Beiyan Wu and Niyang Lin

    Citation: BMC Pediatrics 2020 20:179

    Content type: Research article

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  9. Despite increased understanding of Adverse Childhood Experiences (ACEs), very little advancement has been made in how ACEs are defined and conceptualized. The current objectives were to determine: 1) how well ...

    Authors: Tracie O. Afifi, Samantha Salmon, Isabel Garcés, Shannon Struck, Janique Fortier, Tamara Taillieu, Ashley Stewart-Tufescu, Gordon J. G. Asmundson, Jitender Sareen and Harriet L. MacMillan

    Citation: BMC Pediatrics 2020 20:178

    Content type: Research article

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  10. Busulfan (Bu) is a key component of several conditioning regimens used before hematopoietic stem cell transplantation (HSCT). However, the optimum systemic exposure (expressed as the area under the concentrati...

    Authors: Xinying Feng, Yunjiao Wu, Jingru Zhang, Jiapeng Li, Guanghua Zhu, Duanfang Fan, Changqing Yang and Libo Zhao

    Citation: BMC Pediatrics 2020 20:176

    Content type: Review

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  11. Successful audiology service delivery depends on support from the community, and agreement to utilize hearing healthcare programs. Assessment of parents’ awareness regarding hearing loss (HL) and audiology ser...

    Authors: Ali Mohammed Alsudays, Abdulmajeed Abdullah Alharbi, Faris Saleh Althunayyan, Abdulrahman Abdullah Alsudays, Sultan Mohammed Alanazy, Osama Al-Wutay and Mazyad Marji Alenezi

    Citation: BMC Pediatrics 2020 20:175

    Content type: Research article

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  12. During childhood and adolescence leading behavioural risk factors for the development of cardiometabolic diseases include poor diet quality and sedentary lifestyle. The aim of this study was to determine the f...

    Authors: Hannah L. Mayr, Felicity Cohen, Elizabeth Isenring, Stijn Soenen and Skye Marshall

    Citation: BMC Pediatrics 2020 20:174

    Content type: Research article

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  13. Spontaneous bleedings occurring into joints (hemarthrosis) are the most common manifestations of hemophilia and causes severe joint damage ultimately resulting in joint disfunction known as hemophilic arthropa...

    Authors: Mario Edgar Tena-Sanabria, Yoriko Fabiola Rojas-Sato, José Carlos Castañeda-Resendiz, Gabriela Fuentes-Herrera, Félix Alejandro Álvarez-Martínez, Yureni Iraí Tena-Gonzalez and Juan Carlos Núñez-Enríquez

    Citation: BMC Pediatrics 2020 20:173

    Content type: Research article

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  14. There is a limited understanding of the patient and family experience of Chronic Transfusion Therapy (CTT) for prevention of complications of Sickle Cell Disease (SCD). We sought to understand patient and fami...

    Authors: Lauren M. Hawkins, Cynthia B. Sinha, Diana Ross, Marianne E. M. Yee, Maa-Ohui Quarmyne, Lakshmanan Krishnamurti and Nitya Bakshi

    Citation: BMC Pediatrics 2020 20:172

    Content type: Research article

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  15. X-linked inhibitor of apoptosis (XIAP) deficiency is a rare primary immunodeficiency disease characterized by haemophagocytic lymphohistiocytosis, recurrent splenomegaly and inflammatory bowel disease (IBD). T...

    Authors: Jiamei Tang, Xiaoying Zhou, Lan Wang, Guorui Hu, Bixia Zheng, Chunli Wang, Yan Lu, Yu Jin, Hongmei Guo and Zhifeng Liu

    Citation: BMC Pediatrics 2020 20:171

    Content type: Case report

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  16. Systemic fungal infection (SFI) is one of leading causes of morbidity and mortality in very low birth weight (VLBW) preterm infants. Because early diagnosis of SFI is challenging due to nonspecific manifestati...

    Authors: Lily Rundjan, Retno Wahyuningsih, Chrissela Anindita Oeswadi, Miske Marsogi and Ayu Purnamasari

    Citation: BMC Pediatrics 2020 20:170

    Content type: Research article

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  17. Many children and their families are affected by premature birth. Yet, little is known about their healthcare access and adverse family impact during early childhood. This study aimed to (1) examine difference...

    Authors: Olivia J. Lindly, Morgan K. Crossman, Amy M. Shui, Dennis Z. Kuo, Kristen M. Earl, Amber R. Kleven, James M. Perrin and Karen A. Kuhlthau

    Citation: BMC Pediatrics 2020 20:168

    Content type: Research article

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  18. Mental health disorders in the child and adolescent population are a pressing public health concern. Despite the high prevalence of psychopathology in this vulnerable population, the transition from Child and ...

    Authors: P. Santosh, L. Adams, F. Fiori, N. Davidović, G. de Girolamo, G. C. Dieleman, T. Franić, N. Heaney, K. Lievesley, J. Madan, A. Maras, M. Mastroianni, F. McNicholas, M. Paul, D. Purper-Ouakil, I. Sagar-Ouriaghli…

    Citation: BMC Pediatrics 2020 20:167

    Content type: Study protocol

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  19. Diagnostic evaluation of febrile young infants is challenging. Empirical antimicrobial treatment is therefore common practice in this setting despite high percentage of causative viral infections. The objectiv...

    Authors: Paolo Paioni, Florence Barbey, Christa Relly, Patrick Meyer Sauteur and Christoph Berger

    Citation: BMC Pediatrics 2020 20:166

    Content type: Research article

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  20. The neonatal period carries the highest risk of bacterial meningitis (~ 1 in 5000 births), bearing high mortality (~ 10%) and morbidity (20–50%) rates. Lumbar puncture (LP) remains essential to the diagnosis o...

    Authors: Andrew S. J. Marshall, Manish Sadarangani, Alexandra Scrivens, Rachel Williams, Jean Yong, Ursula Bowler, Louise Linsell, Virginia Chiocchia, Jennifer L. Bell, Caz Stokes, Patricia Santhanadass, Eleri Adams, Edmund Juszczak and Charles C. Roehr

    Citation: BMC Pediatrics 2020 20:165

    Content type: Study protocol

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  21. Growing evidence shows that atopic dermatitis (AD), food allergy (FA), allergic rhinitis, and asthma are largely determined during the first 1000 days (time elapsed from conception to the 2nd birthday). The AR...

    Authors: Caroll D. Hernández, Paola Casanello, Paul R. Harris, José A. Castro-Rodríguez, Carolina Iturriaga, Guillermo Perez-Mateluna, Marcelo Farías, Marcela Urzúa, Cherie Hernandez, Carolina Serrano, Mauricio Sandoval, Rodrigo Hoyos-Bachiloglu, Ricardo Uauy and Arturo Borzutzky

    Citation: BMC Pediatrics 2020 20:164

    Content type: Study protocol

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  22. Clinical audit is a process by which physicians or other health care professionals perform a regular and systematic review of their clinical practice and amend it, when necessary. An internal audit allows to r...

    Authors: Raffaele Limauro, Patrizia Gallo, Luigi Cioffi, Angelo Antignani, Valentina Cioffi, Patrizia Calella and Giuliana Valerio

    Citation: BMC Pediatrics 2020 20:163

    Content type: Research article

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  23. With the increase in hospitalization of premature infants in emergency departments and the painful procedure in these sectors, appropriate methods of pain relief are required. This study aimed to compare the e...

    Authors: Athareh Ranjbar, Colleen Bernstein, Mamak Shariat and Hadi Ranjbar

    Citation: BMC Pediatrics 2020 20:162

    Content type: Research article

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  24. Development and evaluation of an accelerometers technique for collecting data for asses balance had reported difficulty due to equilibrium reactions and continuous bursts. The aim of this study is to determine...

    Authors: J. García-Liñeira, J. L. García-Soidán, V. Romo-Pérez and R. Leirós-Rodríguez

    Citation: BMC Pediatrics 2020 20:161

    Content type: Technical advance

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  25. The first month is the most crucial period for child survival. Neonatal mortality continues to remain high with little improvement over the years in Sub-Saharan Africa, including Ethiopia. This region shows th...

    Authors: Assefa Desalew, Yitagesu Sintayehu, Nardos Teferi, Firehiwot Amare, Bifitu Geda, Teshager Worku, Kebebush Abera and Abiyot Asefaw

    Citation: BMC Pediatrics 2020 20:160

    Content type: Research article

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  26. Breastfeeding is associated with health benefits for both the mother and infant and is therefore important to support; moreover, parental leave is a beneficial factor for breastfeeding. The Swedish parental le...

    Authors: Maria Grandahl, Jenny Stern and Eva-Lotta Funkquist

    Citation: BMC Pediatrics 2020 20:159

    Content type: Research article

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  27. Recurrent bacterial infections of the respiratory tract are one of the major clinical features of the primary ciliary dyskinesia (PCD), a rare genetic disease due to malfunctioning of motile cilia. Chronic inf...

    Authors: G. Piatti, M. M. De Santi, A. Farolfi, G. V. Zuccotti, E. D’Auria, M. F. Patria, S. Torretta, D. Consonni and U. Ambrosetti

    Citation: BMC Pediatrics 2020 20:158

    Content type: Research article

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  28. The aim of the study was to examine the contribution of chronological age (CA), skeletal maturation, training experience and concurrent body size descriptors, to inter-individual variance in left ventricular m...

    Authors: Diogo V. Martinho, João Valente-dos-Santos, Manuel J. Coelho-e-Silva, Arturo O. Gutiérrez, João P. Duarte, Pedro Lourenço-Farinha, Leonardo G. O. Luz, João Gonçalves-Santos, Dalmo R. L. Machado, Neiva Leite, Jorge Conde, Joaquim M. Castanheira, Sean P. Cumming, Lauren B. Sherar and Robert M. Malina

    Citation: BMC Pediatrics 2020 20:157

    Content type: Research article

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  29. Lower heart rate variability (HRV) in a newborn might represent a risk factor for unfavourable outcome, a longer recovery after illness, and a sudden infant death. Our aim was to determine whether the newborn’...

    Authors: Petja Fister, Manca Nolimal, Helena Lenasi and Matjaž Klemenc

    Citation: BMC Pediatrics 2020 20:156

    Content type: Research article

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  30. In a randomized controlled trial (RCT) with 8402 stable low birthweight (LBW) infants, majority being late preterm or term small for gestational age, community-initiated KMC (ciKMC) showed a significant improv...

    Authors: Sunita Taneja, Bireshwar Sinha, Ravi Prakash Upadhyay, Sarmila Mazumder, Halvor Sommerfelt, Jose Martines, Suresh Kumar Dalpath, Rakesh Gupta, Patricia Kariger, Rajiv Bahl, Nita Bhandari and Tarun Dua

    Citation: BMC Pediatrics 2020 20:150

    Content type: Research article

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  31. There is enough evidence to believe that young children’s social-emotional problems can have a long-term effect if extra support is not given early. Therefore, early identification of such problems and any dif...

    Authors: Masoud Vaezghasemi, Eva Eurenius, Anneli Ivarsson, Linda Richter Sundberg, Sven-Arne Silfverdal and Marie Lindkvist

    Citation: BMC Pediatrics 2020 20:149

    Content type: Research article

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  32. Neonatal hypothermia is a global health problem and a major factor for neonatal morbidity and mortality, especially in low and middle-income countries. Therefore, this systematic review and meta-analysis aimed...

    Authors: Biruk Beletew, Ayelign Mengesha, Mesfin Wudu and Melese Abate

    Citation: BMC Pediatrics 2020 20:148

    Content type: Research article

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  33. Between-person differences in sedentary patterns should be considered to understand the role of sedentary behavior (SB) in the development of childhood obesity. This study took a novel approach based on compos...

    Authors: Aleš Gába, Željko Pedišić, Nikola Štefelová, Jan Dygrýn, Karel Hron, Dorothea Dumuid and Mark Tremblay

    Citation: BMC Pediatrics 2020 20:147

    Content type: Research article

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  34. Group B streptococcus (GBS)-induced invasive disease is a major cause of illness and death among infants aged under 90 days in China; however, invasive GBS infection remains unknown in China. We aimed to describe...

    Authors: Yao Zhu, Jiayin Wu, Xinyi Zheng, Dengli Liu, Liping Xu, Dongmei Chen, Wenying Qiu, Zhongling Huang, Ronghua Zhong, Ling Chen, Mingyuan He, Simin Ma, Yayin Lin, Xinzhu Lin and Chao Chen

    Citation: BMC Pediatrics 2020 20:146

    Content type: Research article

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  35. A procedure to measure subcutaneous adipose (SAT) using brightness-mode ultrasound has recently been standardized and applied to various groups of adults including underweight, overweight and obese adults. Hig...

    Authors: A. Kelso, W. Müller, A. Fürhapter-Rieger, M. Sengeis, H. Ahammer and J. M. Steinacker

    Citation: BMC Pediatrics 2020 20:145

    Content type: Technical advance

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  36. Lung recruitment at birth has been advocated as an effective method of improving the respiratory transition at birth. Sustained inflations (SI) and dynamic positive end-expiratory pressure (PEEP) were assessed...

    Authors: Zalfa Kanaan, Coralie Bloch-Queyrat, Marouane Boubaya, Vincent Lévy, Pascal Bolot and Paul Waszak

    Citation: BMC Pediatrics 2020 20:144

    Content type: Research article

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  37. The emerging use of video in neonatology units raises ethical and practical questions. This study aims to gain a better understanding of the suitability, limitations and constraints concerning the use of live ...

    Authors: Aude Le Bris, Nadia Mazille-Orfanos, Pauline Simonot, Maude Luherne, Cyril Flamant, Geraldine Gascoin, Gearóid ÓLaighin, Richard Harte and Patrick Pladys

    Citation: BMC Pediatrics 2020 20:143

    Content type: Research article

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  38. Globally, about 2.7 million neonates die annually and more than 99% of these deaths happened in developing countries. Although most neonatal deaths are preventable and attempts had been taken to tackle these d...

    Authors: Banchigizie Adane Mengistu, Ayenew Engida Yismaw, Zelalem Nigussie Azene and Muhabaw Shumye Mihret

    Citation: BMC Pediatrics 2020 20:142

    Content type: Research article

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  39. It is important for healthcare providers to pay attention to parents’ rearing style and children’s physical symptoms to promote a healthy quality of life among children with atopic dermatitis. We aimed to iden...

    Authors: Jeong Won Han and Hanna Lee

    Citation: BMC Pediatrics 2020 20:141

    Content type: Research article

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  40. Recruiting patients to paediatric trials can be challenging, especially in trials that compare markedly different management pathways and are conducted in acute settings. We aimed to enhance informed consent a...

    Authors: Frances C. Sherratt, Lucy Beasant, Esther M. Crawley, Nigel J. Hall and Bridget Young

    Citation: BMC Pediatrics 2020 20:140

    Content type: Research article

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  41. A cluster of cases of unexplained multi-organ failure was reported in children at Bardnesville Junction Hospital (BJH), Monrovia, Liberia. Prior to admission, children’s caregivers reported antibiotic, antimal...

    Authors: Mohamad K. Haidar, Florian Vogt, Kensuke Takahashi, Fanny Henaff, Lisa Umphrey, Nikola Morton, Luke Bawo, Joseph Kerkula, Robin Ferner, Klaudia Porten and Frederic J. Baud

    Citation: BMC Pediatrics 2020 20:139

    Content type: Research article

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