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  1. Mild encephalitis with reversible splenial lesion of the corpus callosum (MERS) is a clinical/radiological syndrome characterized by hyperintense signal changes in the splenium of the corpus callosum visible o...

    Authors: Louise Le Soudéer, Jeanne Truong, Julie Le Gal and Simon Escoda
    Citation: BMC Pediatrics 2022 22:421
  2. Food insecurity, an important social determinant of health among children, has become more common during the COVID-19 pandemic. Children with chronic diseases including end-stage kidney disease (ESKD) are at h...

    Authors: Melvin Chan, Reya Mokiao, Amy C. Wilson, Neha Pottanat, Sangeeta Hingorani and Michelle C. Starr
    Citation: BMC Pediatrics 2022 22:420
  3. Despite numerous efforts to improve the quality of maternal and child health medical services, over 20 million babies are born with low birth weights each year globally. However, factors related to low birth w...

    Authors: Elias Yadeta Debele, Merga Dheresa, Dawit Tamiru, Tegenu Balcha Wadajo, Kasiye Shiferaw, Lemesa Abdisa Sori and Nega Assefa
    Citation: BMC Pediatrics 2022 22:419
  4. We report five patients with Mayer-Rokitansky-Küster-Hauser syndrome (MRKHS), four of whom presented with precocious puberty and one with growth hormone deficiency (GHD. Our five children add to the growing en...

    Authors: Zhuanzhuan Ai, Xiaoyun Zhu, Hong Chen and Ruimin Chen
    Citation: BMC Pediatrics 2022 22:418
  5. With the advent of the electronic age, the prolonged screen time (ST) of preschoolers in China is relatively high and is on the rise, which is likely to affect preschoolers’ physical and mental health. This st...

    Authors: Xinyao Wang, Yan Wu, Chunhua Yao, Xiangting Wu, Yuqian Ruan and Sunyue Ye
    Citation: BMC Pediatrics 2022 22:417
  6. Lifestyle behaviour in children and adolescents has become increasingly sedentary and occupied with digital work. Concurrently, there has been an increase in the prevalence of headache, neck- and low back pain...

    Authors: Hanne-Mari Schiøtz Thorud, Randi Mork, Cecilie Onshuus Bjørset, Stuart J. Gilson, Lene A. Hagen, Trine Langaas, Hilde R. Pedersen, Ellen Svarverud, Gro Horgen Vikesdal and Rigmor C. Baraas
    Citation: BMC Pediatrics 2022 22:416

    The Correction to this article has been published in BMC Pediatrics 2022 22:454

  7. The clinical spectrum of Cerebral palsy (CP) can differ in various places depending upon knowledge of the people and resources for prevention, diagnosis and management. Although studied extensively in high-res...

    Authors: Shipra Chaudhary, Nisha Keshary Bhatta, Prakash Poudel, Jyoti Agrawal, Rosan Prasad Shah Kalawar and Jitendra Prasad Jayswal
    Citation: BMC Pediatrics 2022 22:415
  8. Despite the potential benefits of effective communication, telling a child that they have a life-threatening condition is one of the most daunting challenges. This study aimed to explore the information needs ...

    Authors: Noyuri Yamaji, Yasuko Nagamatsu, Kyoko Kobayashi, Daisuke Hasegawa, Yuki Yuza and Erika Ota
    Citation: BMC Pediatrics 2022 22:414
  9. Hispanic children face disproportionately higher risks for early life obesity and resultant comorbidities such as Type 2 diabetes and fatty liver disease. Sleep habits are modifiable behaviors that impact earl...

    Authors: Megan J. Gray, Christian E. Vazquez and Ojasvie Agnihotri
    Citation: BMC Pediatrics 2022 22:413
  10. Alexander disease (AxD) is classified into AxD type I (infantile) and AxD type II (juvenile and adult form). We aimed to determine the potential genetic cause(s) contributing to the AxD type II manifestations ...

    Authors: Safoura Zardadi, Ehsan Razmara, Maryam Rasoulinezhad, Meisam Babaei, Mohammad Reza Ashrafi, Neda Pak, Masoud Garshasbi and Ali Reza Tavasoli
    Citation: BMC Pediatrics 2022 22:412
  11. Neonatal sepsis is one of the leading causes of neonatal morbidity and mortality in developing countries like Ethiopia. The investigation of neonatal sepsis needs the application of inclusive diagnostic tools....

    Authors: Minichil Worku, Melak Aynalem, Sirak Biset, Berhanu Woldu, Tiruneh Adane and Abiye Tigabu
    Citation: BMC Pediatrics 2022 22:411
  12. Immune reconstitution inflammatory syndrome (IRIS) refers to the phenomenon of intense immune responses against pathogens in patients with AIDS undergoing antiretroviral therapy to reconstitute immune function...

    Authors: Jia-ying Lei, Han Chen, Dun-hua Zhou, Lu-hong Xu, Jian-pei Fang and You-gang Mai
    Citation: BMC Pediatrics 2022 22:410
  13. Refractive errors are relatively common all around the world. In particular, early onset myopia is associated with a significant burden in later life. Little is known about refractive errors in preschool child...

    Authors: Vasanthi Iyer, Clair A. Enthoven, Paula van Dommelen, Ashwin van Samkar, Johanna H. Groenewoud, Vincent V. W. Jaddoe, Sijmen A. Reijneveld and Caroline C. W. Klaver
    Citation: BMC Pediatrics 2022 22:409
  14. Some neonatal intensive care units offer parents webcam systems for times when they cannot be in the ward. Leaving an infant in the ward can be challenging for parents, and trust in the neonatal healthcare pro...

    Authors: Laura Mause, Alinda Reimer, Jan Hoffmann, Till Dresbach, Dirk Horenkamp-Sonntag, Melanie Klein and Nadine Scholten
    Citation: BMC Pediatrics 2022 22:406
  15. The purpose of this study was to determine the eating behaviors, obesity and physical activity status of children of similar ages living in rural and urban areas and to examine these relationships during the c...

    Authors: Mehmet Gülü, Hakan Yapici, Elena Mainer-Pardos, Ana Ruivo Alves and Hadi Nobari
    Citation: BMC Pediatrics 2022 22:405
  16. MYCN oncogene amplification is associated with treatment failure and poor prognosis in neuroblastoma. To date, most detection methods of MYCN focus on DNA copy numbers instead of protein expression, which is the ...

    Authors: Yi Yang, Jie Zhao, Yingwen Zhang, Tianyue Feng, Bo Yv, Jing Wang, Yijin Gao, Minzhi Yin, Jingyan Tang and Yanxin Li
    Citation: BMC Pediatrics 2022 22:404
  17. Fucosidosis is one of the rare autosomal recessive lysosomal storage diseases (LSDs) attributed to FUCA1 variants causing the deficiency of α-L-fucosidase in vivo. Α-L-fucosidase deficiency will cause excessiv...

    Authors: Shao-Jia Mao, Jia Zhao, Zheng Shen and Chao-Chun Zou
    Citation: BMC Pediatrics 2022 22:403
  18. Primary ciliary dyskinesia (PCD) is a rare, inherited disorder of the motile cilia that exhibits genetic and clinical heterogeneity among different populations. PCD diagnosis remains challenging owing to the h...

    Authors: Ying Li, Wenlong Fu, Gang Geng, Jihong Dai, Zhou Fu and Daiyin Tian
    Citation: BMC Pediatrics 2022 22:402
  19. Despite the undeniable diagnostic benefits of urodynamic studies (UDS), their adoption into clinical practice in Africa has been slow. This study aimed to review the use of invasive UDS in children at a tertia...

    Authors: Thembisile Dintle Mosalakatane, Mignon McCulloch, Peter Nourse, Ashton Coetzee, Anne Wright, Jeanette Raad, John Lazarus and Justin Howlett
    Citation: BMC Pediatrics 2022 22:401
  20. Since the first description of paediatric intervertebral disc calcification (IDC) by Báron in 1924, only approximately 400 cases have been reported in the literature. Paediatric IDC combined with ossification ...

    Authors: Cancan Chang, Juan Zhu, Hongyi Li and Qing Yang
    Citation: BMC Pediatrics 2022 22:400
  21. Most studies examining survival of neonates with congenital diaphragmatic hernia (CDH) are in high-income countries. We aimed to describe the management, survival to hospital discharge rate, and factors associ...

    Authors: Lucy Chai See Lum, Tindivanum Muthurangam Ramanujam, Yee Ian Yik, Mei Ling Lee, Soo Lin Chuah, Emer Breen, Anis Siham Zainal-Abidin, Srihari Singaravel, Conjeevaram Rajendrarao Thambidorai, Jessie Anne de Bruyne, Anna Marie Nathan, Surendran Thavagnanam, Kah Peng Eg, Lucy Chan, Mohamed E. Abdel-Latif and Chin Seng Gan
    Citation: BMC Pediatrics 2022 22:396
  22. Early essential newborn care has been implemented in countries regardless high or low neonatal mortality. This study aims to investigate the current practice of skin-to-skin contact (SSC) and its effect on exc...

    Authors: Hoang Thi Nam Giang, Do Thi Thuy Duy, Nguyen Lam Vuong, Nguyen Thi Tu Ngoc, Thu Thi Pham, Le Quang Tuan, Le Oai, Pham Do Thuc Anh, Ton That Khanh, Nguyen Thi Anh Thi, Mai Ngoc Luu, Tran Thi Tuyet Nga, Le Tho Minh Hieu and Nguyen Tien Huy
    Citation: BMC Pediatrics 2022 22:395
  23. Despite global interventions to prevent and control diarrhea, it still remains a public health problem leading to childhood morbidity and mortality majorly in developing countries. In Uganda, diarrhea is among...

    Authors: Robinah Nantege, Dickson Kajoba, Christopher Ddamulira, Fred Ndoboli and David Ndungutse
    Citation: BMC Pediatrics 2022 22:394
  24. Multisystem Inflammatory Syndrome in Children (MIS-C) is an emerging complication of COVID-19 which lacks a definitive diagnostic test and evidence-based guidelines for workup. We sought to assess practitioner...

    Authors: Claudia A. Rosu, Anna M. Martens, Jeffrey Sumner, Eva J. Farkas, Puneeta Arya, Alexy Boudreau Arauz, Vandana L. Madhavan, Hector Chavez, Shawn D. Larson, Oluwakemi Badaki-Makun, Daniel Irimia and Lael M. Yonker
    Citation: BMC Pediatrics 2022 22:392
  25. Excessive use of screen devices and screen time are increasing health problems in children. We aim to describe the electronic screen device usage and determine the factors associated with their use among presc...

    Authors: Asanka Rathnasiri, Harsha Rathnayaka, Nirmani Yasara and Sachith Mettananda
    Citation: BMC Pediatrics 2022 22:390
  26. The 4-item version of the Center of Epidemiological Studies Depression Scale (CES-DC4) is a self-reported questionnaire used to measure depressive symptoms in adolescents, but the psychometric properties of the s...

    Authors: Christine Leonhard Birk Sørensen, Therese Koops Grønborg and Karin Biering
    Citation: BMC Pediatrics 2022 22:388
  27. Down syndrome is associated with various congenital anomalies and metabolic alterations such as hematological alterations. Values for the major hematological indicators vary with age and sex, but these values ...

    Authors: Silvestre García de la Puente, Karla Adney Flores-Arizmendi, Yessica Yuliana Guerrero-Tapia, Tania Tonantzin Vargas-Robledo and Norma Candelaria López-Santiago
    Citation: BMC Pediatrics 2022 22:387
  28. Childhood undernutrition is a major public health concern that needs special attention to achieve 2025 global nutrition targets. Moderate acute malnutrition (MAM), manifest as wasting (low weight-for-height), ...

    Authors: Ishita Mostafa, Shah Mohammad Fahim, Subhasish Das, Md Amran Gazi, Md. Mehedi Hasan, Kazi Nazmus Saqeeb, Mustafa Mahfuz, Hannah B. Lynn, Michael J. Barratt, Jeffrey I. Gordon and Tahmeed Ahmed
    Citation: BMC Pediatrics 2022 22:385
  29. Young children experience physical complaints, like abdominal pain or minor injuries from playing, almost every day. These experiences may shape how they deal with health issues later in life. While models exi...

    Authors: Sterre van der Ziel, Janna M. Gol, Michel J. van Vliet and Judith G. M. Rosmalen
    Citation: BMC Pediatrics 2022 22:383
  30. The most common infection in children with the hepatic disease with or without cirrhotic ascites is spontaneous bacterial peritonitis (SBP), which occurs in the absence of an evident intra-abdominal source of ...

    Authors: Naser Honar, Najmeh Nezamabadipour, Seyed Mohsen Dehghani, Mahmood Haghighat, Mohammad Hadi Imanieh, Maryam Ataollahi, Nader Shakibazad and Hazhir Javaherizadeh
    Citation: BMC Pediatrics 2022 22:382
  31. Despite the high proportion of adolescents living with mental health issues in low- to middle-income countries (LMICs), especially in Botswana, there is a significant deficit of local research to guide an incr...

    Authors: Anthony A. Olashore, Wendy Brooks, Hlanganiso Roy, Fatai Adewole Adebayo and Bonginkosi Chiliza
    Citation: BMC Pediatrics 2022 22:381
  32. Although early home-based upper limb training programs are promising, in-depth understanding of parents’ experiences with these programs is still limited. We developed an early home-based upper limb training p...

    Authors: Anke PM Verhaegh, Nienke B Nuijen, Pauline BM Aarts, Maria W G Nijhuis-van der Sanden, Michèl AAP Willemsen, Brenda E Groen and Johanna E Vriezekolk
    Citation: BMC Pediatrics 2022 22:380
  33. 22q11.2 deletion syndrome (22qDS) is the most common chromosomal microdeletion syndrome and is associated with a high rate of congenital heart disease (CHD) and neurodevelopmental abnormalities. Congenital por...

    Authors: Toshinobu Ifuku, Sayo Suzuki, Yusaku Nagatomo, Ryohei Yokoyama, Yoshiko Yamamura and Keigo Nakatani
    Citation: BMC Pediatrics 2022 22:379
  34. Incontinentia pigmenti (IP) is an X-liked dominant genodermatosis caused by mutations of the IKBKG/NEMO gene. IP is mostly lethal in males in utero, and only very rare male cases with a somatic mosaic mutation or...

    Authors: Miki Kawai, Atsuya Sugimoto, Yasunori Ishihara, Takema Kato and Hiroki Kurahashi
    Citation: BMC Pediatrics 2022 22:378
  35. Double burden of malnutrition is a global problem posing a serious public health challenge especially in low- and middle-income countries including Ethiopia, where a high prevalence of under-nutrition continue...

    Authors: Alem Sebsbie, Abebe Minda and Sindew Ahmed
    Citation: BMC Pediatrics 2022 22:377
  36. Child-oriented goal-setting in pediatric rehabilitation may improve child motivation, engagement in therapy, child outcomes related to therapy, and service delivery efficiency. The primary objective of this tr...

    Authors: Lesley Pritchard-Wiart, Sandy Thompson-Hodgetts, Ashley B. McKillop, Rhonda Rosychuk, Kelly Mrklas, Lonnie Zwaigenbaum, Jennifer Zwicker, John Andersen, Gillian King and Pegah Firouzeh
    Citation: BMC Pediatrics 2022 22:375
  37. This study attempts to explore the influencing factors and solutions of the colloidal gold method for novel coronavirus (2019-nCoV)-specific IgM/IgG antibody detection, summarize the clinical experience and pe...

    Authors: Shuzhi Dai, Jingjing Li, Jing Li, Long Li, Lin Shi, Ling Cao, Xuemei Zhong, Weijie Liu, Ying Wang and Lijuan Ma
    Citation: BMC Pediatrics 2022 22:372
  38. The growth potential in pubertal boys with short stature is limited by the effect of estrogen on epiphyseal fusion. This study aims to identify the efficacy and safety of the combination of growth hormone (GH)...

    Authors: Yaping Ma, Ruofan Jia, Bingyang Xia, Bin Tang and Zhuangjian Xu
    Citation: BMC Pediatrics 2022 22:371
  39. Acute otitis media (AOM) is one of the most common infectious diseases that affects children. Breastfeeding has been linked to a lower risk of AOM in the first three years of childhood. The aim of this study w...

    Authors: Furat K. AL-Nawaiseh, Madi T. Al-Jaghbir, Mohammad S. AL-Assaf, Hala K. AL-Nawaiseh and Majdi. M. Alzoubi
    Citation: BMC Pediatrics 2022 22:370

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