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Table 3 Sensitivity, Specificity, Predictive value, Likelihood ratio of Procalcitonin (> 0.5 ng/mL) for different diagnostic criteria of pneumonia

From: Role of procalcitonin in diagnosis of community acquired pneumonia in Children

 

Sensitivity

Specificity

Likelihood ratio positive

Likelihood ratio negative

Positive predictive value

Negative predictive value

Pneumonia as per any CXR abnormalities

29.7 (23.6, 36.4)

87.5 (80.5, 92.7)

2.4 (1.4, 3.9)

0.8 (0.7, 0.9)

79.5 (70.1, 86.5)

43.2 (40.6, 45.9)

Pneumonia as per presence of consolidation on CXR

34.5 (22.5, 48.1)

79.2 (73.9, 83.8)

1.7 (1.1, 2.5)

0.8 (0.7, 1.01)

25.6 (18.4, 34.5)

85.3 (82.7, 87.6)

Pneumonia as per WHO criteria

23.4(18.8, 28.5)

82.8 (70.6, 91.4)

1.4 (0.7, 2.5, 7.8)

0.9 (0.8, 1.1)

87.9 (80.5, 93)

16.7 (14.9, 18.6)

  1. PCT + ve: Cut-off for positive serum procalcitonin level has been considered at > 0.5 ng/mL, (Values are in % with 95% CI) except likelihood ratios