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  1. Type 1 diabetes occurs more frequently in younger children who are often pre-school age and enter the education system with diabetes-related support needs that evolve over time. It is important that children a...

    Authors: Deborah Edwards, Jane Noyes, Lesley Lowes, Llinos Haf Spencer and John W Gregory
    Citation: BMC Pediatrics 2014 14:228
    Content type: Research article Published on:

  3. Hypoxic-ischemic injury is thought to play a significant role in necrotizing enterocolitis (NEC). Nitric Oxide (NO) is the principal inhibitory neurotransmitter in the gut and is involved in regulation of muco...

    Authors: Kevin Mitchell, Alexander Lyttle, Harish Amin, Huma Shaireen, Helen Lee Robertson and Abhay K Lodha
    Citation: BMC Pediatrics 2014 14:226
    Content type: Research article Published on:

  4. Overweight and obesity are major public health problems in children and adolescents. The purpose of this study was to conduct a systematic review with meta-analysis to determine the effects of exercise (aerobi...

    Authors: George A Kelley, Kristi S Kelley and Russell R Pate
    Citation: BMC Pediatrics 2014 14:225
    Content type: Research article Published on:

  5. Bacterial meningitis is more common in the neonatal period than any other time in life; however, it is still a challenge for the evidence based diagnosis. Strategy for identification of neonatal bacterial meni...

    Authors: Yajuan Wang, Gaili Guo, Huixin Wang, Xuefang Yang, Fang Shao, Caiyun Yang, Wei Gao, Zhujun Shao, Jinjing Zhang, Jie Luo, Yonghong Yang, Fanrong Kong and Bingqing Zhu
    Citation: BMC Pediatrics 2014 14:224
    Content type: Research article Published on:

  6. Effective early intervention to prevent oppositional/conduct disorders requires early identification of children at risk. Patterns of parent-child interaction may predict oppositional/conduct disorders but lar...

    Authors: Christine Puckering, Clare S Allely, Orla Doolin, David Purves, Alex McConnachie, Paul CD Johnson, Helen Marwick, Jon Heron, Jean Golding, Christopher Gillberg and Philip Wilson
    Citation: BMC Pediatrics 2014 14:223
    Content type: Research article Published on:

  7. There is an increasing need for parenting programs aimed at promoting parent–child interaction. A variety of interventions have been proposed. The use of audiovisual materials for parents has been shown to be ...

    Authors: Anna Roia, Elena Paviotti, Valentina Ferluga, Marcella Montico, Lorenzo Monasta, Luca Ronfani and Giorgio Tamburlini
    Citation: BMC Pediatrics 2014 14:222
    Content type: Research article Published on:

  8. Screening tests play a significant role in rapid and reliable assessment of normal individual development in the entire population of children and adolescents. Body posture screening tests carried out at schoo...

    Authors: Ireneusz M Kowalski, Halina Protasiewicz-Fałdowska, Michał Dwornik, Bogusław Pierożyński, Juozas Raistenskis and Wojciech Kiebzak
    Citation: BMC Pediatrics 2014 14:221
    Content type: Research article Published on:

  9. Microphthalmia with linear skin defects (MLS) syndrome is a rare X-linked dominant male-lethal developmental disorder characterized by unilateral or bilateral microphthalmia and linear skin defects of the face...

    Authors: Lucia Margari, Annalisa Colonna, Francesco Craig, Mattia Gentile, Giustina Giannella, Anna Linda Lamanna and Anna Rosi Legrottaglie
    Citation: BMC Pediatrics 2014 14:220
    Content type: Case report Published on:

  10. Pathogenesis of intraventricular hemorrhage (IVH) in premature infants is multifactorial. Little is known about the impact of genetic variants in the vitamin K-dependent coagulation system on the development o...

    Authors: Christine Schreiner, Sévérine Suter, Matthias Watzka, Hans-Jörg Hertfelder, Felix Schreiner, Johannes Oldenburg, Peter Bartmann and Axel Heep
    Citation: BMC Pediatrics 2014 14:219
    Content type: Research article Published on:

  11. Determining the background incidence of intussusception is important in countries implementing rotavirus immunization. Rotavirus immunization was introduced into the routine infant immunization program in Isra...

    Authors: Khitam Muhsen, Eias Kassem, Sigalit Efraim, Sophy Goren, Dani Cohen and Moshe Ephros
    Citation: BMC Pediatrics 2014 14:218
    Content type: Research article Published on:

  12. Many children who are victims of non-accidental trauma (NAT) may be repeatedly evaluated for injuries related to maltreatment. The purpose of this study was to identify risk factors for repeated injuries in ch...

    Authors: Katherine J Deans, Jonathan Thackeray, Jonathan I Groner, Jennifer N Cooper and Peter C Minneci
    Citation: BMC Pediatrics 2014 14:217
    Content type: Research article Published on:

  14. The speeding increase and the high prevalence of childhood obesity is a serious problem for Public Health. Community Based Interventions has been developed to combat against the childhood obesity epidemic. How...

    Authors: Santiago F Gomez, Rafael Casas, Vanessa Taylor Palomo, Anna Martin Pujol, Montserrat Fíto and Helmut Schröder
    Citation: BMC Pediatrics 2014 14:215
    Content type: Study protocol Published on:

  15. The effect of oral polio vaccine administered already at birth (OPV0) on child survival was not examined before being recommended in 1985. Observational data suggested that OPV0 was harmful for boys, and trial...

    Authors: Najaaraq Lund, Sofie Biering-Sørensen, Andreas Andersen, Ivan Monteiro, Luis Camala, Mathias Jul Jørgensen, Peter Aaby and Christine Stabell Benn
    Citation: BMC Pediatrics 2014 14:214
    Content type: Research article Published on:

  16. It is now recognized that preterm infants ≤28 weeks gestation can be effectively supported from the outset with nasal continuous positive airway pressure. However, this form of respiratory therapy may fail to ...

    Authors: Peter A Dargaville, Camille Omar F Kamlin, Antonio G De Paoli, John B Carlin, Francesca Orsini, Roger F Soll and Peter G Davis
    Citation: BMC Pediatrics 2014 14:213
    Content type: Study protocol Published on:

  17. Antimicrobial use is very common in hospitalized children. An assessment of clinician’s prevailing knowledge and clinical approach to prescribing antimicrobials is helpful in order to develop the best strategi...

    Authors: Jennifer Bowes, Abdool S Yasseen III, Nicholas Barrowman, Barbara Murchison, Judy Dennis, Katherine A Moreau, Nisha Varughese and Nicole Le Saux
    Citation: BMC Pediatrics 2014 14:212
    Content type: Research article Published on:

  18. Dietary behaviours and physical activity are modifiable risk factors to address increasing levels of obesity among children and adolescents, and consequently to reduce later cardiovascular and metabolic diseas...

    Authors: Heather M Sedibe, Kathleen Kahn, Kerstin Edin, Tabitha Gitau, Anneli Ivarsson and Shane A Norris
    Citation: BMC Pediatrics 2014 14:211
    Content type: Research article Published on:

  19. The mitochondrial m.1555A>G mutation is associated with a high rate of permanent hearing loss, if aminoglycosides are given. Preterm infants have an increased risk of permanent hearing loss and are frequently ...

    Authors: Wolfgang Göpel, Sandra Berkowski, Michael Preuss, Andreas Ziegler, Helmut Küster, Ursula Felderhoff-Müser, Ludwig Gortner, Michael Mögel, Christoph Härtel and Egbert Herting
    Citation: BMC Pediatrics 2014 14:210
    Content type: Research article Published on:

  20. Unintentional injuries are a major cause of death among children. Data suggest that the retention of knowledge and skills about first aid declined over time. The purpose of this study was to assess the effects...

    Authors: Feng Li, Xiaoyang Sheng, Jinsong Zhang, Fan Jiang and Xiaoming Shen
    Citation: BMC Pediatrics 2014 14:209
    Content type: Research article Published on:

  21. Little evidence exists regarding the optimal concentration of oxygen to use in the treatment of term neonates with spontaneous pneumothorax (SP). The practice of using high oxygen concentrations to promote “ni...

    Authors: Huma Shaireen, Yacov Rabi, Amy Metcalfe, Majeeda Kamaluddeen, Harish Amin, Albert Akierman and Abhay Lodha
    Citation: BMC Pediatrics 2014 14:208
    Content type: Research article Published on:

  22. Brain-water content (BWC) decreases with maturation of the brain and potentially affects parameters of cerebral oxygenation determined by near-infrared spectroscopy (NIRS). Most commercially available devices ...

    Authors: Anja Demel, Martin Wolf, Christian F Poets and Axel R Franz
    Citation: BMC Pediatrics 2014 14:206
    Content type: Research article Published on:

  25. Developments in enzyme replacement therapy have kindled discussions on adding Pompe disease, characterized by progressive muscle weakness and wasting, to neonatal screening. Pompe disease does not fit traditio...

    Authors: Carla G van El, Tessel Rigter, Arnold JJ Reuser, Ans T van der Ploeg, Stephanie S Weinreich and Martina C Cornel
    Citation: BMC Pediatrics 2014 14:203
    Content type: Research article Published on:

  26. Attention-deficit/hyperactivity disorder (ADHD) is the most common neurobehavioral disorder of childhood and has often a chronic course persisting into adulthood. However, up to 30% of children treated with st...

    Authors: Martin Holtmann, Benjamin Pniewski, Daniel Wachtlin, Sonja Wörz and Ute Strehl
    Citation: BMC Pediatrics 2014 14:202
    Content type: Study protocol Published on:

  27. Gitelman syndrome is an autosomal recessive tubulopathy characterized by hypokalemia, hypomagnesemia, metabolic alkalosis and hypocalciuria. The majority of patients do not present with symptoms until late chi...

    Authors: Karim Bouchireb, Olivia Boyer, Lamisse Mansour-Hendili, Arnaud Garnier, Laurence Heidet, Patrick Niaudet, Remi Salomon and Rosa Vargas Poussou
    Citation: BMC Pediatrics 2014 14:201
    Content type: Case report Published on:

  28. In 2001 when 7-valent pneumococcal conjugate vaccine (PCV7) was introduced, almost all (90%) young Australian Indigenous children living in remote communities had some form of otitis media (OM), including 24% ...

    Authors: Amanda Jane Leach, Christine Wigger, Ross Andrews, Mark Chatfield, Heidi Smith-Vaughan and Peter Stanley Morris
    Citation: BMC Pediatrics 2014 14:200
    Content type: Research article Published on:

  29. The pediatric complex chronic conditions (CCC) classification system, developed in 2000, requires revision to accommodate the International Classification of Disease 10th Revision (ICD-10). To update the CCC c...

    Authors: Chris Feudtner, James A Feinstein, Wenjun Zhong, Matt Hall and Dingwei Dai
    Citation: BMC Pediatrics 2014 14:199
    Content type: Technical advance Published on:

  32. Mannitol- and exercise bronchial provocation tests are both used to diagnose exercise-induced bronchoconstriction. The study aim was to compare the short-term treatment response to budesonide and montelukast o...

    Authors: Salome Schafroth Török, Thomas Mueller, David Miedinger, Anja Jochmann, Ladina Joos Zellweger, Sabine Sauter, Alexandra Goll, Prashant N Chhajed, Anne B Taegtmeyer, Bruno Knöpfli and Jörg D Leuppi
    Citation: BMC Pediatrics 2014 14:196
    Content type: Research article Published on:

  33. Internet risk has been recognised as a child safety problem, but evidence is insufficient to conclude that a child’s online risk exposure can lead to physical harm. This study aims to explore the ecological re...

    Authors: King-wa Fu, Chung-hong Chan and Patrick Ip
    Citation: BMC Pediatrics 2014 14:195
    Content type: Research article Published on:

  34. Trauma in pediatric patients is a major cause of death. This study investigated differences between decedents and survivors. Furthermore, an analysis of preventable and potential preventable trauma deaths was ...

    Authors: Carsten Schoeneberg, Marc Schilling, Judith Keitel, Manuel Burggraf, Bjoern Hussmann and Sven Lendemans
    Citation: BMC Pediatrics 2014 14:194
    Content type: Research article Published on:

  35. Vancomycin is effective against gram-positive bacteria and the first-line antibiotic for treatment of proven coagulase-negative staphylococcal infections. The aim of this study is bipartite: first, to assess t...

    Authors: Fleur S Sinkeler, Timo R de Haan, Caspar J Hodiamont, Yuma A Bijleveld, Dasja Pajkrt and Ron A A Mathôt
    Citation: BMC Pediatrics 2014 14:193
    Content type: Research article Published on:

  36. Children and adolescents with cerebral palsy suffer from higher levels of pain than their peers without disability. The aim of this study was to explore the impact of pain on health-related quality of life and...

    Authors: Marta Badia, Inmaculada Riquelme, Begoña Orgaz, Raquel Acevedo, Egmar Longo and Pedro Montoya
    Citation: BMC Pediatrics 2014 14:192
    Content type: Research article Published on:

  37. An increase in cryptorchidism has been reported in many countries. One mechanism could be low fetal testosterone production possibly secondary to altered placental human chorionic gonadotrophin (hCG) release. ...

    Authors: Carole Chedane, Hugues Puissant, Dominique Weil, Stéphanie Rouleau and Régis Coutant
    Citation: BMC Pediatrics 2014 14:191
    Content type: Research article Published on:

  38. Posterior reversible encephalopathy syndrome is a potentially reversible clinicoradiologic syndrome characterized by headache, mental confusion, visual disturbances and seizures associated with posterior cereb...

    Authors: Gregorio Paolo Milani, Alberto Edefonti, Giacomo Tardini, Elisa Arturi, Claudia Maria Cinnante, Emanuela Anna Laicini, Ernesto Leva, Alberto Maria Cappellari, Carlo Agostoni and Emilio Filippo Fossali
    Citation: BMC Pediatrics 2014 14:190
    Content type: Case report Published on:

  39. To determine the serotypes of Streptococcus pneumoniae responsible for pneumonia complicated by parapneumonic effusion in children, we performed real-time PCR based pneumococcal “serotyping” directly on parapneum...

    Authors: Robert Slinger, Lucie Hyde, Ioana Moldovan, Francis Chan and Jeffrey M Pernica
    Citation: BMC Pediatrics 2014 14:189
    Content type: Research article Published on:

  40. Permanent neonatal diabetes mellitus (PNDM) is a rare disease, which is defined as the onset of diabetes before the age of 6 months with persistence through life. Infants with KCNJ11 or ABCC8 genetic mutations ma...

    Authors: Ke Huang, Li Liang, Jun-feng Fu and Guan-pin Dong
    Citation: BMC Pediatrics 2014 14:188
    Content type: Case report Published on:

  41. In Sub-Saharan Africa over one million newborns die annually. We developed a sustainable and scalable home-based counselling intervention for delivery by community volunteers in rural southern Tanzania to impr...

    Authors: Suzanne Penfold, Fatuma Manzi, Elibariki Mkumbo, Silas Temu, Jennie Jaribu, Donat D Shamba, Hassan Mshinda, Simon Cousens, Tanya Marchant, Marcel Tanner, David Schellenberg and Joanna Armstrong Schellenberg
    Citation: BMC Pediatrics 2014 14:187
    Content type: Research article Published on:

  42. Provision of optimal nutrition in children in critical care is often challenging. This study evaluated exclusive enteral nutrition (EN) provision practices and explored predictors of energy intake and delay of...

    Authors: Jackie Mara, Emma Gentles, Hani A Alfheeaid, Krystalia Diamantidi, Neil Spenceley, Mark Davidson, David Young and Konstantinos Gerasimidis
    Citation: BMC Pediatrics 2014 14:186
    Content type: Research article Published on:

  43. Maternal depressive symptoms are negatively associated with early child growth in developing countries; however, few studies have examined this relation in developed countries or used a longitudinal design wit...

    Authors: Pamela J Surkan, Anna K Ettinger, Rebecca S Hock, Saifuddin Ahmed, Donna M Strobino and Cynthia S Minkovitz
    Citation: BMC Pediatrics 2014 14:185
    Content type: Research article Published on:

  44. Because early life growth has long-lasting metabolic and behavioral consequences, intervention during this period of developmental plasticity may alter long-term obesity risk. While modifiable factors during i...

    Authors: Ian M Paul, Jennifer S Williams, Stephanie Anzman-Frasca, Jessica S Beiler, Kateryna D Makova, Michele E Marini, Lindsey B Hess, Susan E Rzucidlo, Nicole Verdiglione, Jodi A Mindell and Leann L Birch
    Citation: BMC Pediatrics 2014 14:184
    Content type: Study protocol Published on:

  45. Continuous glucose monitoring (CGM) has been shown to improve glucose control in adults with type 1 diabetes. Effectiveness of CGM is directly linked with CGM adherence, which can be challenging to maintain in...

    Authors: Margaret L Lawson, Brenda Bradley, Karen McAssey, Cheril Clarson, Susan E Kirsch, Farid H Mahmud, Jacqueline R Curtis, Christine Richardson, Jennilea Courtney, Tammy Cooper, Cynthia J Downie, Gopalan Rajamannar and Nicholas Barrowman
    Citation: BMC Pediatrics 2014 14:183
    Content type: Study protocol Published on:

  46. Perinatal stroke is a leading cause of early brain injury, cerebral palsy, and lifelong neurological morbidity. No study to date has examined the impact of raising a child with perinatal stroke on parents and ...

    Authors: Taryn B Bemister, Brian L Brooks, Richard H Dyck and Adam Kirton
    Citation: BMC Pediatrics 2014 14:182
    Content type: Research article Published on:

  47. Non-infection caused urticaria is a common ailment in adolescents. Its symptoms (e.g., unusual rash appearance, limitation of daily activities, and recurrent itching) may contribute to the development of depre...

    Authors: Chia-Lun Kuo, Chi-Yen Chen, Hui-Ling Huang, Wen-Liang Chen, Hua-Chin Lee, Chih-Yu Chang, Chu-Chung Chou, Shinn-Ying Ho, Han-Ping Wu and Yan-Ren Lin
    Citation: BMC Pediatrics 2014 14:181
    Content type: Research article Published on:

  48. In many resource-limited settings, the availability of effective phototherapy for jaundiced infants is frequently hampered by lack of, or inadequate resources to acquire and maintain conventional electric-powe...

    Authors: Bolajoko O Olusanya, Zainab O Imam, Cecilia A Mabogunje, Abieyuwa A Emokpae and Tina M Slusher
    Citation: BMC Pediatrics 2014 14:180
    Content type: Research article Published on:

  50. Despite therapeutic hypothermia 30-70% of newborns with moderate or severe hypoxic ischemic encephalopathy will die or survive with significant long-term impairments. Magnetic resonance imaging (MRI) in the fi...

    Authors: Thais Agut, Marisol León, Mónica Rebollo, Jordi Muchart, Gemma Arca and Alfredo Garcia-Alix
    Citation: BMC Pediatrics 2014 14:177
    Content type: Research article Published on:
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BMC Pediatrics

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