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  1. Premature preterm rupture of membranes (PPROM) is reported to be associated with high rates of neonatal mortality and morbidity. Sildenafil has been used in infants with persistent pulmonary hypertension of ne...

    Authors: Karen Lavie-Nevo, Kevin C. Harris and Joseph Y. Ting
    Citation: BMC Pediatrics 2019 19:416
  2. Obesity is associated with many chronic diseases including cortisol rhythm disorder and low testosterone. Furthermore, studies on obese children are quite limited and no concordance results have been obtained,...

    Authors: Bingyan Cao, Chunxiu Gong, Di Wu, Xuejun Liang, Wenjing Li, Min Liu, Chang Su, Miao Qin, Xi Meng and Liya Wei
    Citation: BMC Pediatrics 2019 19:414
  3. Professional support in pediatric and rehabilitation care environments has been recommended as a means to build youth competence in life skills during their transition to adulthood. Life skills are the essenti...

    Authors: Shauna Kingsnorth, Alanna E. F. Rudzik, Gillian King and Amy C. McPherson
    Citation: BMC Pediatrics 2019 19:413
  4. Inhaled corticosteroids (ICS) are the most effective treatment for children with persistent asthma. However adverse effects of ICS on Hypothalamo Pituitary Adrenal (HPA) axis, growth and bone metabolism are a ...

    Authors: Anuradha KWDA, Prematilake GLDC, Batuwita BAUI, Kannangoda KASR, Hewagamage US, Wijeratne S, Lankatilake Kantha and de Silva KSH
    Citation: BMC Pediatrics 2019 19:411
  5. To explore the changes of inflammatory and oxidative stress responses in Henoch-Schönlein purpura (HSP) children, and further analyzed the therapeutic effects and mechanisms of hemoperfusion (HP) on HSP with s...

    Authors: Ying Zhu, Yang Dong, Lin Wu and Fang Deng
    Citation: BMC Pediatrics 2019 19:409
  6. Infants are in a state of rapid development and maturation; the growth rate is most rapid during the first 4 to 6 months of life. Few studies indicated that in developing countries including Ethiopia the preva...

    Authors: Lakew Abebe, Mamusha Aman, Shifera Asfaw, Hailay Gebreyesus, Mebrahtu Teweldemedhin and Abebe Mamo
    Citation: BMC Pediatrics 2019 19:408
  7. The use of oral (PO) antibiotics following a course of certain intravenous (IV) antibiotics is proposed in order to avoid the complications of IV medications and to decrease the cost. However, the efficacy and...

    Authors: Chuan Wang, Yanan Li and Yi Ji
    Citation: BMC Pediatrics 2019 19:407
  8. Kawasaki disease (KD) is a common vasculitis of childhood in East Asia. The complications of KD ascribed to long-term cardiovascular sequelae are considerably diverse. Although studies have investigated neurod...

    Authors: Chien-Heng Lin, Wei-De Lin, I-Ching Chou, Inn-Chi Lee and Syuan-Yu Hong
    Citation: BMC Pediatrics 2019 19:406
  9. An increasing number of extremely preterm (EP) infants have survived worldwide. However, few data have been reported from China. This study was designed to investigate the short-term outcomes of EP infants at ...

    Authors: Fan Wu, Guosheng Liu, Zhoushan Feng, Xiaohua Tan, Chuanzhong Yang, Xiaotong Ye, Yiheng Dai, Weiyi Liang, Xiuzhen Ye, Jing Mo, Lu Ding, Benqing Wu, Hongxiang Chen, Chiwang Li, Zhe Zhang, Xiao Rong…
    Citation: BMC Pediatrics 2019 19:405
  10. The factors that determine the effect of enteral feeding on intestinal perfusion after preterm birth remain largely unknown. We aimed to determine the effect of enteral feeding on intestinal oxygen saturation (ri...

    Authors: Sara J. Kuik, Anne G. J. F. van Zoonen, Arend F. Bos, Koenraad N. J. A. Van Braeckel, Jan B. F. Hulscher and Elisabeth M. W. Kooi
    Citation: BMC Pediatrics 2019 19:404
  11. Previous studies showed that parents of very preterm infants expressed feelings of incompetence and experienced high levels of stress upon the discharge of their infants. We conducted a systematic review of se...

    Authors: S. Y. Lee, J. P. C. Chau, K. C. Choi and S. H. S. Lo
    Citation: BMC Pediatrics 2019 19:402
  12. Mexico occupies one of the first places worldwide in childhood obesity. Its Mestizo and Indigenous communities present different levels of westernization which have triggered different epidemiological diseases...

    Authors: Paula Costa-Urrutia, Rafael Álvarez-Fariña, Carolina Abud, Valentina Franco-Trecu, Julián Esparza-Romero, Cruz Mónica López-Morales, Martha Eunice Rodríguez-Arellano, Jaime Valle Leal, Valentina Colistro and Julio Granados
    Citation: BMC Pediatrics 2019 19:401
  13. Epilepsy is a complex disorder caused by various factors, including genetic aberrance. Recent studies have identified an essential role of the sodium channel Nav1.6, encoded by the gene SCN8A, in epileptic enceph...

    Authors: Kao-Min Lin, Geng Su, Fengpeng Wang, Xiaobin Zhang, Yuanqing Wang, Jun Ren, Xin Wang, Yi Yao and Ying Zhou
    Citation: BMC Pediatrics 2019 19:400
  14. Acute seizures are common in pediatric cerebral malaria (CM), but usual care with phenobarbital risks respiratory suppression. We undertook studies of enteral levetiracetam (eLVT) to evaluate pharmacokinetics ...

    Authors: Gretchen L. Birbeck, Susan T. Herman, Edmund V. Capparelli, Fraction K. Dzinjalamala, Samah G. Abdel Baki, Macpherson Mallewa, Neema M. Toto, Douglas G. Postels, Joseph C. Gardiner, Terrie E. Taylor and Karl B. Seydel
    Citation: BMC Pediatrics 2019 19:399
  15. Otitis Media (OM) is the most common disease of childhood. Twenty thousand people die each year from otitis media. It is an important cause of preventable hearing loss, affects children's intellectual performa...

    Authors: Bereket Tadesse, Techalew Shimelis and Mesfin Worku
    Citation: BMC Pediatrics 2019 19:398
  16. More research is needed about the association between physical activity (PA), sedentary behaviour (SB), and adiposity in preschoolers, particularly using more direct clinical measures of adiposity. Therefore, ...

    Authors: Amar Arhab, Nadine Messerli-Bürgy, Tanja H. Kakebeeke, Kerstin Stülb, Annina Zysset, Claudia S. Leeger-Aschmann, Einat A. Schmutz, Andrea H. Meyer, Simone Munsch, Susi Kriemler, Oskar G. Jenni and Jardena J. Puder
    Citation: BMC Pediatrics 2019 19:397
  17. The global HIV burden among adolescents ages 10–19 is growing. This population concurrently confronts the multifaceted challenges of adolescence and living with HIV. With the goal of informing future intervent...

    Authors: Carly A. Rodriguez, Emiliano Valle, Jerome Galea, Milagros Wong, Lenka Kolevic, Maribel Muñoz, Leonid Lecca and Molly F. Franke
    Citation: BMC Pediatrics 2019 19:396
  18. Several studies have investigated motor and cognitive skills in infants as well as gross motor abilities in schoolchildren treated for congenital idiopathic clubfoot, mostly indicating specific impairments in ...

    Authors: Julia Dillmann, Gudrun Schwarzer and Christian-Dominik Peterlein
    Citation: BMC Pediatrics 2019 19:394
  19. The Canadian Hospitals Injury Reporting Prevention Program (CHIRPP) is a sentinel surveillance program that collects and analyzes data on injuries and poisonings of people presenting to emergency departments (...

    Authors: Aimée Campeau, Lil Tonmyr, Erik Gulbransen, Martine Hébert, Steven McFaull and Robin Skinner
    Citation: BMC Pediatrics 2019 19:393
  20. Current use of smartphone cameras by parents create opportunities for longitudinal home-video-assessments to monitor infant development. We developed and validated a home-video method for parents, enabling Ped...

    Authors: M. Boonzaaijer, F. van Wesel, J. Nuysink, M. J. M. Volman and M. J. Jongmans
    Citation: BMC Pediatrics 2019 19:392
  21. Thyroid hormones are critical for growth and brain development during the newborn period and infancy. Because of delayed maturation of the hypothalamic-pituitary-thyroid axis in preterm infants, thyroid dysfun...

    Authors: Hye-Rim Kim, Young Hwa Jung, Chang Won Choi, Hye Rim Chung, Min-Jae Kang and Beyong Il Kim
    Citation: BMC Pediatrics 2019 19:391
  22. While the keeping of pets has been shown to protect against childhood allergic disease and obesity, less is known regarding potential associations of prenatal pet keeping and attention deficit hyperactivity di...

    Authors: Andrea E. Cassidy-Bushrow, Alexandra R. Sitarik, Tisa M. Johnson-Hooper, Jannel M. Phillips, Kyra Jones, Christine Cole Johnson and Jennifer K. Straughen
    Citation: BMC Pediatrics 2019 19:390
  23. An increased number of congenital Zika virus infections with neurological and musculoskeletal malformations have been diagnosed worldwide, however, there are still several gaps in the knowledge about this infe...

    Authors: Cláudia de Paula Guimarães, Myrella Silveira Macedo, Maria Alves Barbosa, Solomar Martins Marques, Paulo Sucasas Costa and Ênio Chaves de Oliveira
    Citation: BMC Pediatrics 2019 19:389
  24. The aim of this study is to investigate whether age of infant motor milestone achievement is related to levels of physical activity (PA), weight status and blood pressure at age 4–7 years of age.

    Authors: Silvia I. Brouwer, Ronald P. Stolk and Eva Corpeleijn
    Citation: BMC Pediatrics 2019 19:388
  25. Maintaining neonatal resuscitation skills among health workers in low resource settings will require continuous quality improvement efforts. We aimed to evaluate the effect of skill drills and feedback on neon...

    Authors: Rejina Gurung, Abhishek Gurung, Avinash K. Sunny, Omkar Basnet, Shree Krishna Shrestha, Øystein Herwig Gomo, Helge Myklebust, Sakina Girnary and Ashish KC
    Citation: BMC Pediatrics 2019 19:387
  26. Diarrhea and acute respiratory infection (ARI) are major causes of child mortality. We aimed to identify risk factors associated with diarrhea and ARI among children under 2 years of age in rural northern Bang...

    Authors: Md Barkat Ullah, Malay K. Mridha, Charles D. Arnold, Susana L. Matias, Md Showkat A. Khan, Zakia Siddiqui, Mokbul Hossain, Rina Rani Paul and Kathryn G. Dewey
    Citation: BMC Pediatrics 2019 19:386
  27. Intestinal parasitic infection is diversified illness and diseases caused millions morbidity among under-five children lives in developing countries particularly vulnerable rural communities. Deworming coverag...

    Authors: Eshetu Gadisa and Kefiyalew Jote
    Citation: BMC Pediatrics 2019 19:385
  28. Exclusive breastfeeding (EBF) in the first 6 months of life is the best and most complete option for an infant, in that supplies the vitamins and minerals the baby needs. Several studies in Iran have been cond...

    Authors: Meysam Behzadifar, Mandana Saki, Masoud Behzadifar, Mahnaz Mardani, Fatemeh Yari, Farzad Ebrahimzadeh, Hadis Majidi Mehr, Shadi Abdi Bastami and Nicola Luigi Bragazzi
    Citation: BMC Pediatrics 2019 19:384
  29. Nasal continuous positive airway pressure (CPAP) is widely used in the treatment and prevention of respiratory distress in preterm neonates, with only few severe adverse skin effects reported.

    Authors: P. Zachhau, A. E. Gravergaard and H. T. Christesen
    Citation: BMC Pediatrics 2019 19:383
  30. Although women working in the informal economy are a large and vulnerable group, little is known about infant feeding and childcare practices among these women. The aim of this study was to explore childcare p...

    Authors: Christiane Horwood, Lyn Haskins, Laura Alfers, Zandile Masango-Muzindutsi, Richard Dobson and Nigel Rollins
    Citation: BMC Pediatrics 2019 19:382
  31. Children with sickle cell anemia (SCA) are highly susceptible to stroke and other manifestations of pediatric cerebral vasculopathy. Detailed evaluations in sub-Saharan Africa are limited.

    Authors: Nancy S. Green, Deogratias Munube, Paul Bangirana, Linda Rosset Buluma, Bridget Kebirungi, Robert Opoka, Ezekiel Mupere, Philip Kasirye, Sarah Kiguli, Annet Birabwa, Michael S. Kawooya, Samson K. Lubowa, Rogers Sekibira, Edwards Kayongo, Heather Hume, Mitchell Elkind…
    Citation: BMC Pediatrics 2019 19:381
  32. Acute Respiratory infection accounts for 94,037000 disability adjusted life years and 1.9 million deaths worldwide. Acute respiratory infections is the most common causes of under-five illness and mortality. T...

    Authors: Sielu Alemayehu, Kalayou Kidanu, Tensay Kahsay and Mekuria Kassa
    Citation: BMC Pediatrics 2019 19:380
  33. Neurodevelopmental disability (NDD) is increasingly acknowledged as one of the important causes of disease burden in low income countries. None the less, there is a dearth of data on the burden of NDD and its ...

    Authors: Gertrude Namazzi, Helena Hildenwall, Paul Mubiri, Claudia Hanson, Christine Nalwadda, Margaret Nampijja, Angelina Kakooza-Mwesige, Peter Waiswa and James K. Tumwine
    Citation: BMC Pediatrics 2019 19:379
  34. Research on outcomes associated with lifestyle interventions serving pediatric populations in urban settings, where a majority have severe obesity, is scarce. This study assessed whether participation in a lif...

    Authors: Nagla S. Bayoumi, Elizabeth Helzner, Aimee Afable, Michael A. Joseph and Sarita Dhuper
    Citation: BMC Pediatrics 2019 19:378
  35. Type 1 diabetes (T1D) is a chronic metabolic condition requiring intensive daily self-care to avoid both high and low blood glucose levels. Self-care and glycemic outcomes are particularly problematic in adole...

    Authors: Giesje Nefs, Linh Nguyen, Per Winterdijk, Esther Hartman, Theo Sas, Roos Nuboer, Ineke De Kruijff, Willie Bakker-van Waarde, Henk-Jan Aanstoot and Frans Pouwer
    Citation: BMC Pediatrics 2019 19:377
  36. Childhood and adolescent overweight, obesity and underweight have become an issue of grave concern to both the developed and developing countries in context of global burden of non-communicable diseases. Unhea...

    Authors: Daniel Gyamfi, Christian Obirikorang, Emmanuel Acheampong, Evans Adu Asamoah, Bernard Berko Sampong, Emmanuella Nsenbah Batu and Enoch Odame Anto
    Citation: BMC Pediatrics 2019 19:376
  37. In young children, β-thalassemia major (β-TM) is associated with potentially severe clinical characteristics, including poor growth, feeding difficulties, hepatosplenomegaly, bone metabolic disorders, and skel...

    Authors: Uet Yu, Li Chen, Xiaodong Wang, Xiaoling Zhang, Yue Li, Feiqiu Wen and Sixi Liu
    Citation: BMC Pediatrics 2019 19:375
  38. To evaluate the early growth (weight and length) of HIV-exposed uninfected (HEU) children from the prevention of mother-to-child transmission (PMTCT) of human immunodeficiency virus (HIV) program in Guangdong ...

    Authors: Bing Li, Liu-ying Tang, Zhi-qiang Wang, Shuang Gao, Yun-tao Wu, Hao-li Xu and Yuan-zhu Ma
    Citation: BMC Pediatrics 2019 19:374
  39. Although the sternoclavicular joint (SCJ) may be involved in ankylosing spondylitis, rheumatic arthritis, and Behçet’s disease and participates in the systemic inflammatory process of arthritis, it is often ne...

    Authors: Po-Yu Huang, Ling-Sai Chang, Mindy Ming-Huey Guo and Ho-Chang Kuo
    Citation: BMC Pediatrics 2019 19:373
  40. The revised 2015 Canadian Guidelines requires a more specific prenatal alcohol exposure (PAE) threshold for a Fetal Alcohol Spectrum Disorder (FASD) diagnosis. The unintended consequences of adhering to the su...

    Authors: Susan Petryk, Muhammad A. Siddiqui, Juliet Ekeh and Mamata Pandey
    Citation: BMC Pediatrics 2019 19:372
  41. Adult opioid use and neonatal abstinence syndrome (NAS) are growing public health problems in the United States (U.S.). Our objective was to determine how opioid use disorder treatment access impacts the relat...

    Authors: Elizabeth R. Wolf, Sebastian T. Tong, Roy T. Sabo, Steven H. Woolf, Kassie Abbinanti, James Pecsok and Alex H. Krist
    Citation: BMC Pediatrics 2019 19:371
  42. Newborn screening (NBS) for cystic fibrosis (CF) not only identifies infants with a diagnosis of CF, but also those with an uncertain diagnosis of cystic fibrosis (CF), i.e. CF transmembrane conductance regula...

    Authors: Chee Y. Ooi, Rosie Sutherland, Carlo Castellani, Katherine Keenan, Margaret Boland, Joe Reisman, Candice Bjornson, Mark A. Chilvers, Richard van Wylick, Steven Kent, April Price, Dimas Mateos-Corral, Daniel Hughes, Melinda Solomon, Peter Zuberbuhler, Janna Brusky…
    Citation: BMC Pediatrics 2019 19:369
  43. Aspiration of grass inflorescences is an extremely rare phenomenon with potential diagnostic difficulties. Due to its special shape, each coughing and respiratory action helps its migration towards the periphe...

    Authors: Anna Rieth, Tamás Kovács, Zoltán Novák, Katalin Kapus, Aurél Ottlakán, Tibor Németh and József Furák
    Citation: BMC Pediatrics 2019 19:368

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