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  1. This study aims to determine the prevalence of tobacco smoking and illicit drug use among Dutch adolescents admitted to hospital for acute alcohol intoxication treatment. Furthermore, socio-demographic predict...

    Authors: Loes de Veld, Inge M. Wolberink, Joris J. van Hoof and Nico van der Lely
    Citation: BMC Pediatrics 2021 21:233
  2. Studies suggest that exposure to ambient air pollution during pregnancy may be associated with increased risks of birth defects (BDs), but conclusions have been inconsistent. This study describes the ethnic di...

    Authors: Xiaoli Huang, Jichang Chen, Dingyuan Zeng, Zhong Lin, Carly Herbert, Lesley Cottrell, Liu Liu, Arlene Ash and Bo Wang
    Citation: BMC Pediatrics 2021 21:232
  3. The COVID-19 outbreak has resulted in governments implementing disease containment measures such as school closures, social distancing, and home quarantine.

    Authors: G. Segre, R. Campi, F. Scarpellini, A. Clavenna, M. Zanetti, M. Cartabia and M. Bonati
    Citation: BMC Pediatrics 2021 21:231
  4. Alemtuzumab is a T cell depleting antibody agent used as induction immunosuppressant therapy in solid organ transplant recipients. In addition, it is being increasingly used to treat severe or glucocorticoid-r...

    Authors: Nori J. L. Smeets, Ruud J. R. Eijk, Saskia N. de Wildt and Charlotte M. H. H. T. Bootsma-Robroeks
    Citation: BMC Pediatrics 2021 21:229
  5. Children’s voices are seldom heard in process evaluations concerning health promotion programmes. A Healthy School Start Plus (HSSP) is a parental support programme, conducted in Sweden, with the aim of promot...

    Authors: Mahnoush Etminan Malek, Gisela Nyberg, Liselotte Schäfer Elinder, Emma Patterson and Åsa Norman
    Citation: BMC Pediatrics 2021 21:228
  6. Diarrhea among children under five is one of the significant public health concerns in developing countries, such as Ethiopia that is mainly attributed to inadequate water, sanitation and hygiene (WASH) servic...

    Authors: Weldehawariyat Getahun and Metadel Adane
    Citation: BMC Pediatrics 2021 21:227
  7. Immunization is essential to prevent between 2 and 3 million deaths globally each year and it is widely accepted that it is one of the most cost-effective health interventions. Despite all its advantages, immu...

    Authors: Admassu Ketsela, Seifu Hagos Gebreyesus and Wakgari Deressa
    Citation: BMC Pediatrics 2021 21:226
  8. Physical growth during childhood and adolescence is influenced by both genetic and environmental factors. Heritability, the proportion of phenotypic variance explained by genetic factors, has been demonstrated...

    Authors: Avivit Brener, Yarden Waksman, Talya Rosenfeld, Sigal Levy, Itai Peleg, Adi Raviv, Hagar Interator and Yael Lebenthal
    Citation: BMC Pediatrics 2021 21:225
  9. Neonatal encephalopathy due to acute perinatal asphyxia is a major cause of perinatal brain damage. Moderate to severe neonatal encephalopathy is associated with high mortality and morbidity rates. However, th...

    Authors: Yoshinori Aoki, Tatsuo Kono, Mikako Enokizono and Kaoru Okazaki
    Citation: BMC Pediatrics 2021 21:224
  10. There is a lack of a comprehensive evaluation for pediatric clinical practice guidelines (CPGs) published in recent years. Here, we assessed the quality of pediatric CPGs, considering factors that might affect...

    Authors: Yali Liu, Yuan Zhang, Shu Wang, Ling Liu, Gang Che, Jiahui Niu and Yuan Ma
    Citation: BMC Pediatrics 2021 21:223
  11. Pediatric sepsis remains a significant cause of morbidity and mortality worldwide. This study aimed to identify the incidence of sepsis and septic shock among patients admitted to the pediatric intensive care ...

    Authors: Mohamed O. Humoodi, Mona A. Aldabbagh, Maher M. Salem, Yousef M. Al Talhi, Sara M. Osman, Mohammed Bakhsh, Abdullah M. Alzahrani and Maha Azzam
    Citation: BMC Pediatrics 2021 21:222
  12. Children with acute peripheral facial nerve palsy cannot yet be recommended corticosteroid treatment based on evidence. Adults with idiopathic facial nerve palsy are treated with corticosteroids, according to ...

    Authors: Sofia Karlsson, Sigurdur Arnason, Nermin Hadziosmanovic, Åsa Laestadius, Malou Hultcrantz, Elin Marsk and Barbro H. Skogman
    Citation: BMC Pediatrics 2021 21:220
  13. Centralisation of paediatric intensive care units (PICUs) has the increased the need for specialist paediatric critical care transport teams (PCCT) to transport critically ill children to PICU. We investigated...

    Authors: Sarah E. Seaton, Elizabeth S. Draper, Christina Pagel, Fatemah Rajah, Jo Wray and Padmanabhan Ramnarayan
    Citation: BMC Pediatrics 2021 21:217
  14. Caregivers’ knowledge, practice and adherence in medication administration who care for children with chronic illness requiring long-term pharmacological treatments are factors associating with children medica...

    Authors: Chii-chii Chew, Huan-keat Chan, Chee-tao Chang, Amar-singh HSS and Mohamed azmi Hassali
    Citation: BMC Pediatrics 2021 21:216
  15. Adiposity status in adolescence is associated with various health outcomes in adulthood. Waist circumference [WC] and waist-to-height ratio [WHtR] are measures of abdominal obesity and have shown to be valid p...

    Authors: Felicia J. Setiono, Laura A. Guerra, Cindy Leung and Tashara M. Leak
    Citation: BMC Pediatrics 2021 21:215
  16. Children’s healthy development is important. While governmental public assistance benefits financially troubled families, it cannot compensate for a lack of social support. Single-parenthood is a health risk f...

    Authors: Daisuke Nishioka, Junko Saito, Keiko Ueno and Naoki Kondo
    Citation: BMC Pediatrics 2021 21:214
  17. Previous studies have suggested that choline and betaine are associated with improved anthropometric measures including, BMI and waist circumference however, results are largely inconsistent and limited studie...

    Authors: Alireza Jafari, Yahya Jalilpiran, Katherine Suitor, Nick Bellissimo and Leila Azadbakht
    Citation: BMC Pediatrics 2021 21:213
  18. As preterm infants’ neurodevelopment is shaped by NICU-related factors during their hospitalization, it is essential to evaluate which interventions are more beneficial for their neurodevelopment at this speci...

    Authors: Marilyn Aita, Gwenaëlle De Clifford Faugère, Andréane Lavallée, Nancy Feeley, Robyn Stremler, Émilie Rioux and Marie-Hélène Proulx
    Citation: BMC Pediatrics 2021 21:210
  19. Centronuclear myopathy (CNM), a subtype of congenital myopathy (CM), is a group of clinical and genetically heterogeneous muscle disorders. Since the discovery of the SPEG gene and disease-causing variants, on...

    Authors: Gang Zhang, Min Xu, Tingting Huang, Wenxin Lin, Jinglin Chen, Wangyang Chen and Xingzhi Chang
    Citation: BMC Pediatrics 2021 21:209
  20. Working memory performance is associated with better academic achievements in children and adolescents, and it is positively related to CRF. However, what level of cardiorespiratory fitness (CRF) discriminates...

    Authors: Vinícius Muller Reis Weber, Daniel Zanardini Fernandes, Leonardo Alex Volpato, Maria Raquel de Oliveira Bueno, Marcelo Romanzini, Jose Castro-Piñero and Enio Ricardo Vaz Ronque
    Citation: BMC Pediatrics 2021 21:208
  21. To examine the association of handgrip strength (HGS) and bone mineral density (BMD) of Brazilian children and adolescents.

    Authors: Bruna Thamyres Ciccotti Saraiva, Ricardo Ribeiro Agostinete, Ismael Forte Freitas Júnior, Daniel Eduardo Rodrigues de Sousa, Luis Alberto Gobbo, William Rodrigues Tebar and Diego Giulliano Destro Christofaro
    Citation: BMC Pediatrics 2021 21:207
  22. Inconsistent findings have been reported for associations between protein intake and age at menarche. We aimed to investigate the association between intake of protein and protein-containing food groups during...

    Authors: Nazanin Moslehi, Golaleh Asghari, Parvin Mirmiran and Fereidoun Azizi
    Citation: BMC Pediatrics 2021 21:206
  23. Left ventricular noncompaction cardiomyopathy (LVNC) is characterized by prominent ventricular trabeculations on cardiovascular imaging. Acquired reversible LVNC has not been reported in pediatrics without a g...

    Authors: Riko Kato, Hiromichi Taneichi, Shinya Takarada, Mako Okabe, Nariaki Miyao, Hideyuki Nakaoka, Keijiro Ibuki, Sayaka Ozawa, Yuichi Adachi, Naoki Yoshimura, Kazuyoshi Saito, Fukiko Ichida and Keiichi Hirono
    Citation: BMC Pediatrics 2021 21:205
  24. Presently, 1 in 4 Lebanese adolescents is involved in bullying, with 12% being perpetrators. In Lebanon, around 90% of bullying incidents occur in schools. Given the lack of studies tackling bullying perpetrat...

    Authors: Emmanuelle Awad, Chadia Haddad, Hala Sacre, Rabih Hallit, Michel Soufia, Pascale Salameh, Sahar Obeid and Souheil Hallit
    Citation: BMC Pediatrics 2021 21:204
  25. The study aims to use the cross-lagged model and utilize data from the Born in Shenyang Cohort Study to characterize the bidirectional associations of the term-born infants’ neurodevelopment in five domains an...

    Authors: Xiaotong Wei, Jiajin Hu, Liu Yang, Ming Gao, Lin Li, Ning Ding, Yanan Ma and Deliang Wen
    Citation: BMC Pediatrics 2021 21:203
  26. Respiratory Syncytial Virus (RSV) is the commonest cause of acute lower respiratory infections (ALRI) in infants. However, the burden of RSV is unknown in Ethiopia. We aimed to determine the prevalence, season...

    Authors: Abate Yeshidinber Weldetsadik and Frank Riedel
    Citation: BMC Pediatrics 2021 21:201
  27. Information on the foot structures of Central Anatolian children is limited. Foot structures of children aged 6–10 years were shown to be different according to sex and increasing age.

    Authors: Serap Alsancak, Senem Guner, Enver Güven, Ali Koray Özgün, Yunis Akkaş and Neslihan Alkıs
    Citation: BMC Pediatrics 2021 21:200
  28. Cognitive development after age three tends to be stable and can therefore predict cognitive skills in later childhood. However, there is evidence that cognitive development is less stable before age three. In...

    Authors: Lei Wang, Yifei Chen, Sean Sylvia, Sarah-Eve Dill and Scott Rozelle
    Citation: BMC Pediatrics 2021 21:199
  29. HIV infection is associated with significant neurocognitive deficits making maximization of cognitive function among children receiving antiretroviral therapy (ART) a public health imperative. Non-protease inh...

    Authors: Damalie Nalwanga, Victor Musiime, Paul Bangirana, Erika Phelps Nishiguchi, Andrew Kiggwe, Titus Ssesanga, John M. Ssenkusu, Philippa Musoke and Sarah E. Cusick
    Citation: BMC Pediatrics 2021 21:198
  30. Atopic diseases and behavioural difficulties in children have both been on the rise in recent decades. This study seeks to assess associations between atopic diseases and behavioural difficulties, examining th...

    Authors: Wiebke Keller, Mandy Vogel, Freerk Prenzel, Jon Genuneit, Anne Jurkutat, Cornelia Hilbert, Andreas Hiemisch, Wieland Kiess and Tanja Poulain
    Citation: BMC Pediatrics 2021 21:197
  31. Household food insecurity (FI), even at marginal levels, is associated with poor child health outcomes. The Nutrition Screening Tool for Every Preschooler (NutriSTEP®) is a valid and reliable 17-item parent-co...

    Authors: Imaan Bayoumi, Catherine S. Birken, Kimberly M. Nurse, Patricia C. Parkin, Jonathon L. Maguire, Colin Macarthur, Janis A. Randall Simpson and Cornelia M. Borkhoff
    Citation: BMC Pediatrics 2021 21:196
  32. To investigate the impact of protective measures and isolation on respiratory tract infections in children during the COVID-19 outbreak.

    Authors: Yueling Zhu, Wei Li, Binbin Yang, Ruiying Qian, Fang Wu, Xue He, Qinheng Zhu, Jinling Liu, Yan Ni, Jianbing Wang and Shanshan Mao
    Citation: BMC Pediatrics 2021 21:195
  33. Ewing’s sarcoma is a common malignant bone tumor in children and young adults. Rarely, extra-skeletal soft tissues and visceral organs can also be the site of origin of Ewing’s sarcoma. Primary pulmonary Ewing...

    Authors: Xuefeng Ling, Jianlin Tong, Liangliang Wang, Chuan Yao and Zhiying Chen
    Citation: BMC Pediatrics 2021 21:194
  34. Child malnutrition is a huge health problem having multifaceted consequences for child survival and long-term well-being. Although, several studies investigated stunting, underweight, and wasting in low- and m...

    Authors: Lijalem Melie Tesfaw and Haile Mekonnen Fenta
    Citation: BMC Pediatrics 2021 21:193
  35. Pneumonia is the leading cause of death and hospitalization among young children worldwide, but its risk factors remain unclear.

    Authors: Xiangrong Zheng, Jian Kuang, Chan Lu, Qihong Deng, Haiyu Wu, Rachael Gakii Murithi, McSherry Brownel Johnson, Wang Peng and Maolan Wu
    Citation: BMC Pediatrics 2021 21:192
  36. Delayed diagnosis of congenital heart disease (CHD) causes significant morbidity and mortality. We aimed to determine the proportion of delayed diagnosis of CHD and factors related to the delayed diagnosis.

    Authors: Indah K. Murni, Muhammad Taufik Wirawan, Linda Patmasari, Esta R. Sativa, Nadya Arafuri, Sasmito Nugroho and Noormanto
    Citation: BMC Pediatrics 2021 21:191
  37. Neural tube defects are common congenital anomalies that result from early malformation in the development of the spinal cord and brain. It is related to substantial mortality, morbidity, disability, and psych...

    Authors: Mohammed Oumer, Ashenafi Tazebew and Mezgebu Silamsaw
    Citation: BMC Pediatrics 2021 21:190
  38. In most studies, the virological response is assessed during the first two years of antiretroviral treatment initiated in HIV-infected infants. However, early initiation of antiretroviral therapy exposes infan...

    Authors: Francis Ateba Ndongo, Mathurin Cyrille Tejiokem, Calixte Ida Penda, Suzie Tetang Ndiang, Jean-Audrey Ndongo, Georgette Guemkam, Casimir Ledoux Sofeu, Paul Alain Tagnouokam-ngoupo, Anfumbom Kfutwah, Philippe Msellati, Albert Faye and Josiane Warszawski
    Citation: BMC Pediatrics 2021 21:189
  39. Bloodstream infection (BSI) resulting from ESKAPEEc pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Escherichia coli, Acinetobacter baumannii, Pseudomonas aeruginosa and Enterobacte...

    Authors: Xiaoshan Peng, Wei Zhou, Yu Zhu and Chaomin Wan
    Citation: BMC Pediatrics 2021 21:188
  40. Childhood-onset systemic lupus erythematosus (cSLE) is a kind of chronic inflammatory disease characterized by a highly abnormal immune system. This study aimed to detect the serum levels of Th (T helper) cyto...

    Authors: Wei Quan, Jingnan An, Gang Li, Guanghui Qian, Meifang Jin, Chenxi Feng, Si Li, Xiaozhong Li, Yunyun Xu and Xiaohan Hu
    Citation: BMC Pediatrics 2021 21:187
  41. HIV is a major contributor to infant mortality. A significant gap remains between the uptake of infant and maternal antiretroviral regimens and only a minority of HIV-exposed infants receives prophylaxis and s...

    Authors: Lilian M. N. Kebaya, Dalton Wamalwa, Nyambura Kariuki, Bashir Admani, Philip Ayieko and Ruth Nduati
    Citation: BMC Pediatrics 2021 21:186
  42. Childhood obesity is a public health problem with repercussions in later life. As tissue formation peaks in childhood we determined how weight status influences bone mineral content.

    Authors: Francisco Sánchez Ferrer, Ernesto Cortes Castell, Francisco Carratalá Marco, Mercedes Juste Ruiz, José Antonio Quesada Rico and Ana Pilar Nso Roca
    Citation: BMC Pediatrics 2021 21:185
  43. Characteristics of obstructive sleep apnea (OSA) changes with age. Infants, toddlers and prepubertal children with OSA are usually underweight and may suffer from failure to thrive (FTT). Adenotonsillectomy (T...

    Authors: Keren Nathan, Galit Livnat, Liat Feraru and Giora Pillar
    Citation: BMC Pediatrics 2021 21:184

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