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  1. Severe acute malnutrition affects around 17 million under-five children in the world, of which the highest burden is accounted by Sub-Saharan Africa where Ethiopia is found. Though there are few individual, in...

    Authors: Zebenay Workneh Bitew, Ayinalem Alemu and Teshager Worku

    Citation: BMC Pediatrics 2020 20:335

    Content type: Research article

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  2. Neurally adjusted ventilatory assist (NAVA) is an innovative mode for assisted ventilation that improves patient-ventilator interaction in children. The aim of this study was to assess the effects of patient-v...

    Authors: Giorgia Spinazzola, Roberta Costa, Daniele De Luca, Giovanna Chidini, Giuliano Ferrone, Marco Piastra and Giorgio Conti

    Citation: BMC Pediatrics 2020 20:334

    Content type: Research article

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  3. The aim of this study was to determine, retrospectively, the serum 25OHD and calcium concentrations of screened neonates of mothers at high risk of 25OHD deficiency and examine whether their measurement contri...

    Authors: Sheikh Arif M. Kozgar, Paul Chay and Craig F. Munns

    Citation: BMC Pediatrics 2020 20:332

    Content type: Research article

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  4. Roughly 10% of newborns need help to complete the transition of birth. For these infants, international guidelines recommend supporting them using a 4-step procedure (A to D). Step A is an assessment time, whi...

    Authors: Claire Boithias, Laure Jule, Stephanie Le Foulgoc, Gilles Jourdain and Dan Benhamou

    Citation: BMC Pediatrics 2020 20:331

    Content type: Research article

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  5. Young children with developmental disabilities and delays spend significant amounts of time at home, show decreased participation in home-based activities, and receive home-based early intervention services to...

    Authors: M. A. Khetani, B. M. McManus, E. C. Albrecht, V. C. Kaelin, J. K. Dooling-Litfin and E. A. Scully

    Citation: BMC Pediatrics 2020 20:330

    Content type: Research article

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  6. Mental health problems often arise in childhood and adolescence and can have detrimental effects on people’s quality of life (QoL). Therefore, it is of great importance for clinicians, policymakers and researc...

    Authors: Jochen O. Mierau, Daphne Kann-Weedage, Pieter J. Hoekstra, Lisan Spiegelaar, Danielle E. M. C. Jansen, Karin M. Vermeulen, Sijmen A. Reijneveld, Barbara J. van den Hoofdakker, Erik Buskens, M. Elske van den Akker-van Marle, Carmen D. Dirksen and Annabeth P. Groenman

    Citation: BMC Pediatrics 2020 20:329

    Content type: Research article

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  7. Participation in organized sports is associated with higher physical activity (PA) levels in school-aged-children. Yet, little is known about PA determinants in preschool-aged-children. We examined association...

    Authors: Chu Chen, Fanny Sellberg, Viktor H. Ahlqvist, Martin Neovius, Filip Christiansen and Daniel Berglind

    Citation: BMC Pediatrics 2020 20:328

    Content type: Research article

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  8. 13q33–q34 microdeletions are rare chromosomal aberrations associated with a high risk of developmental disability, facial dysmorphism, cardiac defects and other malformation of organs. It is necessary to colle...

    Authors: Xue He, Huijun Shen, Haidong Fu, Chunyue Feng, Zhixia Liu, Yanyan Jin and Jianhua Mao

    Citation: BMC Pediatrics 2020 20:327

    Content type: Case report

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  9. Dried blood spots (DBS) have been proposed as potentially tool for detecting invasive bacterial diseases.

    Authors: Fabiana C. Pimenta, Benild Moiane, Fernanda C. Lessa, Anne-Kathryn L. Venero, Iaci Moura, Shanda Larson, Sergio Massora, Alberto Chaúque, Nelson Tembe, Helio Mucavele, Jennifer R. Verani, Cynthia G. Whitney, Betuel Sigaúque and Maria G. S. Carvalho

    Citation: BMC Pediatrics 2020 20:326

    Content type: Research article

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  10. Many obese children have at least one obese parent, and some of them have one parent who had undergone bariatric surgery (“bariatric families”). The perceptions and attitudes towards child obesity of parents i...

    Authors: Netta Weiss, Nataly Kalamitzky, Hagar Interator, Ronit Lubetzky and Hadar Moran-Lev

    Citation: BMC Pediatrics 2020 20:325

    Content type: Research article

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  11. Lower limb serial casting is commonly used therapeutically in paediatric clinical practice with some evidence to support its efficacy. This systematic review aimed to determine the effects of serial casting in...

    Authors: Nikki Milne, Michelle Miao and Emma Beattie

    Citation: BMC Pediatrics 2020 20:324

    Content type: Research article

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  12. With the importance of early childhood development more recognized by the international society, low-cost and cross-culturally comparable measures of early childhood development is in great demand, both in Chi...

    Authors: Jin Zhao, Sally Anne Brinkman, Yunting Zhang, Yingquan Song, Chunling Lu, Mary Eming Young, Yue Zhang, Patrick Ip, Wenjie Shan and Fan Jiang

    Citation: BMC Pediatrics 2020 20:323

    Content type: Research article

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  13. More than 50% of newborns with congenital heart disease (CHD) are unrecognized at birth; however, the use of echocardiogram (Echo) for diagnosing CHD in newborns with asymptomatic, non-syndromic cardiac murmur...

    Authors: Shin Ae Yoon, Woi Hyun Hong and Hwa Jin Cho

    Citation: BMC Pediatrics 2020 20:322

    Content type: Research article

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  14. The objective of this prospective, multicentre, observational cohort study was to evaluate the association between admission hypothermia and neonatal outcomes in very low-birth weight (VLBW) infants in multipl...

    Authors: Yong-hui Yu, Li Wang, Lei Huang, Li-ling Wang, Xiao-yang Huang, Xiu-fang Fan, Yan-jie Ding, Cheng-yuan Zhang, Qiang Liu, Ai-rong Sun, Yue-hua Zhao, Guo Yao, Cong Li, Xiu-xiang Liu, Jing-cai Wu, Zhen-ying Yang…

    Citation: BMC Pediatrics 2020 20:321

    Content type: Research article

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  15. Alveolar capillary dysplasia (ACD) is a rare cause of severe pulmonary hypertension and respiratory failure in neonates. The onset of ACD is usually preceded by a short asymptomatic period. The condition is re...

    Authors: Zuzanna Kozłowska, Zuzanna Owsiańska, Joanna P. Wroblewska, Apolonia Kałużna, Andrzej Marszałek, Yogen Singh, Bartłomiej Mroziński, Qian Liu, Justyna A. Karolak, Paweł Stankiewicz, Gail Deutsch, Marta Szymankiewicz-Bręborowicz and Tomasz Szczapa

    Citation: BMC Pediatrics 2020 20:320

    Content type: Case report

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  16. Hyperacusis is a chronic condition commonly defined as a lowered tolerance or increased sensitivity to everyday environmental sounds. It has been viewed as a paediatric disorder which can cause significant imp...

    Authors: Iskra Potgieter, Kathryn Fackrell, Veronica Kennedy, Rosa Crunkhorn and Derek J. Hoare

    Citation: BMC Pediatrics 2020 20:319

    Content type: Research article

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  17. The occurrence of multiple endocrine neoplasia type 2B (MEN2B) in Asians is very rare. In particular, patients with intractable constipation as the main clinical manifestation are even rarer. Atypical clinical...

    Authors: Lidan Zhang, Yan Guo, Lei Ye, Wenli Lu, Zhiya Dong, Wei Wang and Yuan Xiao

    Citation: BMC Pediatrics 2020 20:318

    Content type: Case report

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  18. Continuous monitoring of SpO2 in the neonatal ICU is the standard of care. Changes in SpO2 exposure have been shown to markedly impact outcome, but limiting extreme episodes is an arduous task. Much more complica...

    Authors: Thomas E. Bachman, Narayan P. Iyer, Christopher J. L. Newth, Patrick A. Ross and Robinder G. Khemani

    Citation: BMC Pediatrics 2020 20:317

    Content type: Research article

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  19. PPP3CA gene encodes the catalytic subunit A of a calcium-dependent protein phosphatase called calcineurin. However, two distinct mechanisms in PPP3CA deficiency would cause two clinically different diseases. Gain...

    Authors: Sai Yang, Xiang Shen, Qingyun Kang, Xiaojun Kuang, Zeshu Ning, Shulei Liu, Hongmei Liao, Zhenhua Cao and Liming Yang

    Citation: BMC Pediatrics 2020 20:315

    Content type: Case report

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  20. Depression is one of the most prevalent mental health problems among adolescents. Mental health problems might be the result of child abuse considering that their prevalences are increasing simultaneously in I...

    Authors: Meita Dhamayanti, Anindita Noviandhari, Nina Masdiani, Veranita Pandia and Nanan Sekarwana

    Citation: BMC Pediatrics 2020 20:313

    Content type: Research article

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  21. Early antibiotic exposure may be contributing to the onset of childhood allergies. The main objective of this study was to conduct a systematic review on the relationship between early life antibiotic exposure...

    Authors: Ruth Baron, Meron Taye, Isolde Besseling-van der Vaart, Joanne Ujčič-Voortman, Hania Szajewska, Jacob C. Seidell and Arnoud Verhoeff

    Citation: BMC Pediatrics 2020 20:312

    Content type: Research article

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  22. Sleep-disordered breathing (SDB) is a common syndrome in children, related to their immune responses, cardiovascular function, and neurocognitive function. This study aimed to determine the prevalence of SDB a...

    Authors: Yun Guo, Zhenzhen Pan, Fei Gao, Qian Wang, Shanshan Pan, Shiyao Xu, Yu Hui, Ling Li and Jun Qian

    Citation: BMC Pediatrics 2020 20:310

    Content type: Research article

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  23. Persistent and chronic diarrhea is difficult to treat, and infection is still the main cause. In this study, we investigate the application value of xTAG gastrointestinal pathogen panel (xTAG GPP) multiplex PC...

    Authors: Chunli Wang, Xiaoying Zhou, Mengshu Zhu, Hanjun Yin, Jiamei Tang, Yan Huang, Bixia Zheng, Yu Jin and Zhifeng Liu

    Citation: BMC Pediatrics 2020 20:309

    Content type: Research article

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  24. The prevalence of child and adolescent obesity and severe obesity continues to increase despite decades of policy and research aimed at prevention. Obesity strongly predicts cardiovascular and metabolic diseas...

    Authors: Sarah C. Armstrong, McAllister Windom, Nathan A. Bihlmeyer, Jennifer S. Li, Svati H. Shah, Mary Story, Nancy Zucker, William E. Kraus, Neha Pagidipati, Eric Peterson, Charlene Wong, Manuela Wiedemeier, Lauren Sibley, Samuel I. Berchuck, Peter Merrill, Alexandra Zizzi…

    Citation: BMC Pediatrics 2020 20:308

    Content type: Study protocol

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  25. The clients’ willingness to accept (WTA) and willingness to pay (WTP) for a given good or service can help elicit the monetary value of that good or service. This study aims to assess the WTA and WTP of mother...

    Authors: Satar Rezaei, Abraha Woldemichael, Masoumeh Mirzaei, Shima Mohammadi and Behzad Karami Matin

    Citation: BMC Pediatrics 2020 20:307

    Content type: Research article

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  26. Nocturnal enuresis (NE) has a negative impact on children’s health and imposes a long-term burden on families. With economic development and cultural improvements, parents and medical professionals pay more at...

    Authors: Hui-Mei Huang, Jing Wei, Shristi Sharma, Ying Bao, Fei Li, Jian-Wen Song, Hai-Bin Wu, Hong-Li Sun, Zhi-Juan Li, Huan-Nan Liu, Qian Wu and Hong-Li Jiang

    Citation: BMC Pediatrics 2020 20:305

    Content type: Research article

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  27. Chronic Non-Infectious Osteomyelitis (CNO) is a chronic, relapsing, self-limiting inflammation of the bone. Although it is rare, CNO has been associated with inflammatory bowel disease and frequently precedes ...

    Authors: Alyssa Lorenze, Lukas Meadows, Temitope Kehinde and Cortney Ballengee Menchini

    Citation: BMC Pediatrics 2020 20:304

    Content type: Case report

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  28. Globally, possible serious bacterial infection [PSBI] is a cause for about 600,000 newborn deaths per year. To decrease the burden of this infection, a community-based management newborn PSBI when referral to ...

    Authors: Kasahun Girma Tareke, Yohannes Kebede Lemu and Garumma Tolu Feyissa

    Citation: BMC Pediatrics 2020 20:303

    Content type: Research article

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  29. Understanding the genetics underlying the heritable subphenotypes of sickle cell anemia, specific to each population, would be prognostically useful and could inform personalized therapeutics.The objective of ...

    Authors: Abdourahim Chamouine, Thoueiba Saandi, Mathias Muszlak, Juliette Larmaraud, Laurent Lambrecht, Jean Poisson, Julien Balicchi, Serge Pissard and Narcisse Elenga

    Citation: BMC Pediatrics 2020 20:302

    Content type: Research article

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  30. Reaching the bedside of a critically ill child within three hours of agreeing the child requires intensive care is a key target for Paediatric Critical Care Transport teams (PCCTs) to achieve in the United Kin...

    Authors: Sarah E. Seaton, Padmanabhan Ramnarayan, Patrick Davies, Emma Hudson, Stephen Morris, Christina Pagel, Fatemah Rajah, Jo Wray and Elizabeth S. Draper

    Citation: BMC Pediatrics 2020 20:301

    Content type: Research article

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  31. Angola is one of the southern African countries with the highest prevalence of anaemia. Identifying anaemia determinants is an important step for the design of evidence-based control strategies. In this study,...

    Authors: Cláudia Fançony, Ânia Soares, João Lavinha, Henrique Barros and Miguel Brito

    Citation: BMC Pediatrics 2020 20:298

    Content type: Research article

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  32. Currently in the United States, childhood injuries are the leading cause of mortality and morbidity, resulting in an estimated 9.2 million emergency department visits and $17 billion annually in medical costs....

    Authors: Colleen M. Heflin, Irma Arteaga, Jean Felix Ndashimye and Matthew P. Rabbitt

    Citation: BMC Pediatrics 2020 20:297

    Content type: Research article

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  33. Several environmental factors favour the occurrence of acute respiratory disease, which is the main reason for paediatric consultations in our country (Colombia). Tobacco smoke is considered a significant envi...

    Authors: María Fernanda Tovar, Wendy Ortiz, María Alejandra Valderrama, Fabio Rodríguez, Oscar Gamboa, María José Maldonado and Sergio Iván Agudelo

    Citation: BMC Pediatrics 2020 20:296

    Content type: Research article

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  34. Childhood vaccinations are a vital preventive measure to reduce disease incidence and deaths among children. As a result, immunisation coverage against measles was a key indicator for monitoring the fourth Mil...

    Authors: Swati Srivastava, Jasmine Fledderjohann and Ashish Kumar Upadhyay

    Citation: BMC Pediatrics 2020 20:295

    Content type: Research article

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  35. Fibroblast growth factor 19 (FGF19), fibroblast growth factor 21 (FGF21) and Klotho are regulators of energy homeostasis. However, in the pediatric population, the relationships between obesity, metabolic diso...

    Authors: Anna Socha-Banasiak, Arkadiusz Michalak, Krzysztof Pacześ, Zuzanna Gaj, Wojciech Fendler, Anna Socha, Ewa Głowacka, Karolina Kapka, Violetta Gołąbek and Elżbieta Czkwianianc

    Citation: BMC Pediatrics 2020 20:294

    Content type: Research article

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  36. Rapid weight gain (RWG) has been recognized as an important determinant of childhood obesity. This study aims to explore the RWG distribution among children at six-month intervals from birth to two years old a...

    Authors: Yi-Fan Li, Shio-Jean Lin and Tung-liang Chiang

    Citation: BMC Pediatrics 2020 20:293

    Content type: Research article

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  37. The fundamental treatment for patients with pediatric malignant mediastinal tumors is chemotherapy. Therefore, accurate diagnosis is essential for selecting the appropriate chemotherapeutic regimen. However, m...

    Authors: Tomoko Tanaka, Hizuru Amano, Yujiro Tanaka, Yoshiyuki Takahashi, Tatsuro Tajiri, Takahisa Tainaka, Chiyoe Shirota, Wataru Sumida, Kazuki Yokota, Satoshi Makita, Yukiko Tani, Akinari Hinoki and Hiroo Uchida

    Citation: BMC Pediatrics 2020 20:292

    Content type: Research article

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  38. Psychological and behavioral correlates are considered important in the development and persistence of obesity in both adults and youth. This study aimed to identify such features in youth with severe obesity ...

    Authors: Vidhu V. Thaker, Stavroula K. Osganian, Sarah D. deFerranti, Kendrin R. Sonneville, Jennifer K. Cheng, Henry A. Feldman and Tracy K. Richmond

    Citation: BMC Pediatrics 2020 20:291

    Content type: Research article

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  39. Previous studies have shown that changes in intestinal microfloras are associated with both gastrointestinal (GI) and non-GI tumors. It is not clear whether there is an association between GI microflora change...

    Authors: Xiaolin Gao, Ruixue Miao, Yiping Zhu, Chao Lin, Xue Yang, Ruizhen Jia, Kuang Linghan, Chaomin Wan and Jianjun Deng

    Citation: BMC Pediatrics 2020 20:290

    Content type: Research article

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  40. Secondary hemophagocytic lymphohistiocytosis (HLH) is a rare hyperinflammatory syndrome that requires prompt diagnosis and appropriate treatment. A risk-stratification model that could be used to identify high-.....

    Authors: Hua Pan, Gaoyan Wang, Enben Guan, Liang Song, Aiqin Song, Xiaodan Liu, Zhi Yi and Li-rong Sun

    Citation: BMC Pediatrics 2020 20:288

    Content type: Research article

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  41. Bainbridge–Ropers syndrome (BRPS) is a recently described developmental disorder caused by de novo truncating mutations in the Additional sex combs-like 3 (ASXL3) gene. Only four cases have been reported in Ch...

    Authors: Linfeng Yang, Bin Guo, Weiwei Zhu, Lei Wang, Bingjuan Han, Yena Che and Lingfei Guo

    Citation: BMC Pediatrics 2020 20:287

    Content type: Case report

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  42. Viral respiratory infections (VRIs) are a frequent cause of hospitalization in children under 24 months of age. A history of prematurity or heart disease may be a risk factor for complications in patients hosp...

    Authors: Jessie N. Zurita-Cruz, Alejandro Gutierrez-Gonzalez, Leticia Manuel-Apolinar, José Esteban Fernández-Gárate, María Luisa Arellano-Flores, Roberto Alejandro Correa Gonzalez, Guillermo Vázquez-Rosales, Rocio Sanchez-Armas and Nelly Cisneros-González

    Citation: BMC Pediatrics 2020 20:285

    Content type: Research article

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  43. Histoplasmosis is a rare infectious condition with mainly pulmonary involvement. Disseminated histoplasmosis may occur in immunocompromised condition. It can present in different ways but jaundice and ascites ...

    Authors: Luthfun Nahar, Md Benzamin, Naznin Sarkar, Urmi Roy, Kamrun Nahar, Md Rukunuzzaman, Khan Lamia Nahid, A. S. M. Bazlul Karim and Bishnu Pada Dey

    Citation: BMC Pediatrics 2020 20:284

    Content type: Case report

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