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  1. The peritonitis rate among children treated with peritoneal dialysis (PD) has not been widely reported in Saudi Arabia. The study aim was to estimate the peritonitis rate per patient-year and investigate the f...

    Authors: Khamisa Al Mokali, Zahra Al Sannaa, Faten Al Mutairi and Anwar E. Ahmed

    Citation: BMC Pediatrics 2020 20:42

    Content type: Research article

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  2. Maternally inherited complex I deficiencies due to mutations in MT-ND genes represent a heterogeneous group of multisystem mitochondrial disorders (MD) with a unfavourable prognosis. The aim of the study was to c...

    Authors: Tereza Danhelovska, Hana Kolarova, Jiri Zeman, Hana Hansikova, Manuela Vaneckova, Lukas Lambert, Vendula Kucerova-Vidrova, Kamila Berankova, Tomas Honzik and Marketa Tesarova

    Citation: BMC Pediatrics 2020 20:41

    Content type: Research article

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  3. In Canada alone, almost 3000 VLBW infants are born and treated annually with almost 1200 going onto death or survival with severe brain injury, chronic lung disorders, aggressive retinopathy of prematurity, la...

    Authors: Elizabeth V. Asztalos, Keith Barrington, Abhay Lodha, William Tarnow-Mordi and Andrew Martin

    Citation: BMC Pediatrics 2020 20:40

    Content type: Study protocol

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  4. Little is known whether children experience pain during hospital stay from the child’s own perspective or not. The existing studies tend to be based on a small number of children and therefore have limitations...

    Authors: V. Vejzovic, J. Bozic, G. Panova, M. Babajic and A-C Bramhagen

    Citation: BMC Pediatrics 2020 20:39

    Content type: Research article

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  5. The well-being of mothers of infants requiring Neonatal Intensive Care Unit (NICU) hospitalization may be affected by the architectural design of the unit. A few recent studies suggest there may be some drawba...

    Authors: Nancy Feeley, Stephanie Robins, Christine Genest, Robyn Stremler, Phyllis Zelkowitz and Lyne Charbonneau

    Citation: BMC Pediatrics 2020 20:38

    Content type: Research article

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  6. Retinoblastoma is an ocular tumor in infants with cancer predisposition. Treatment of the rare tumor needs to be optimized for ocular preserved survival without second primary malignancy (SPM).

    Authors: Tamaki Ueda, Yuhki Koga, Hiroshi Yoshikawa, Mika Tanabe, Kanako Yamana, Utako Oba, Kentaro Nakashima, Hiroaki Ono, Takuya Ichimura, Shunji Hasegawa, Wakako Kato, Tetsuko Kobayashi, Hideki Nakayama, Yasunari Sakai, Tadamasa Yoshitake, Saiji Ohga…

    Citation: BMC Pediatrics 2020 20:37

    Content type: Research article

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  7. Neonatal seizures are difficult to diagnose and, when they are, tradition dictates first line treatment is phenobarbital. There is little data on how consultants diagnose neonatal seizures, choose when to trea...

    Authors: Lucy Gossling, James J. P. Alix, Theocharis Stavroulakis and Anthony R. Hart

    Citation: BMC Pediatrics 2020 20:36

    Content type: Research article

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  8. The relationship between constipation and childhood nocturnal enuresis (NE) has been previously reported; however, this relationship remains controversial. The present study aimed to evaluate the association b...

    Authors: Yu-Chao Hsiao, Jen-Hung Wang, Chia-Ling Chang, Chia-Jung Hsieh and Ming-Chun Chen

    Citation: BMC Pediatrics 2020 20:35

    Content type: Research article

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  9. Acrodermatitis enteropathica (AE) is a rare autosomal recessive hereditary skin disease caused by mutations in the SLC39A4 gene and is characterized by periorificial dermatitis, alopecia and diarrhoea due to i...

    Authors: Wei Zhong, Chao Yang, Lei Zhu, Yu-Qi Huang and Yong-Feng Chen

    Citation: BMC Pediatrics 2020 20:34

    Content type: Case report

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  10. The first 28 days of aliveness are the biggest challenge mentioned for the continuity of life for children. In Ethiopia, despite a significant reduction in under-five mortality during the last 15 years, neonat...

    Authors: Alaka Adiso Limaso, Mesay Hailu Dangisso and Desalegn Tsegaw Hibstu

    Citation: BMC Pediatrics 2020 20:33

    Content type: Research article

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  11. An increased incidence of type 2 diabetes in youth is occurring worldwide. While diverse ethnic groups are disproportionately affected by type 2 diabetes, studies that explore ethnic differences and undiagnose...

    Authors: Shelley Spurr, Jill Bally, Carol Bullin, Diane Allan and Erick McNair

    Citation: BMC Pediatrics 2020 20:31

    Content type: Research article

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  12. Weight is critical for the medical management of infants; however, scales can be unavailable or inaccessible in some practice settings. We recently developed and validated a robust infant weight estimation met...

    Authors: Susan M. Abdel-Rahman, Ian M. Paul, Paula Delmore, Jia-Yuh Chen, Mary Mills and Rachel G. Greenberg

    Citation: BMC Pediatrics 2020 20:30

    Content type: Research article

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  13. Intestinal parasites are the commonest cause of childhood diarrhea and malnutrition in Ethiopia. Information about intestinal parasites is the first fundamental step for designing intervention strategies again...

    Authors: Berhan Tsegaye, Amanuel Yoseph and Hunachew Beyene

    Citation: BMC Pediatrics 2020 20:28

    Content type: Research article

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  14. Globally, the incidence of sleep-related infant mortality declined dramatically following the first public health campaigns seen internationally in the 1990s to reduce the risks of sudden infant death. However...

    Authors: Roni Cole, Jeanine Young, Lauren Kearney and John M. D. Thompson

    Citation: BMC Pediatrics 2020 20:27

    Content type: Research article

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  15. Congenital hypothyroidism is a common, yet easily treatable cause of poor growth and intellectual disability. Newborn screening programs play an important role in the early detection and treatment of congenita...

    Authors: Selorm A. Dei-Tutu, Adoma Manful, Douglas C. Heimburger, Hawa Malechi, Daniel J. Moore, Samuel A. Oppong, William E. Russell and Muktar H. Aliyu

    Citation: BMC Pediatrics 2020 20:26

    Content type: Research article

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  16. Obesity has been longitudinally associated with depression but only few studies take a life course approach. This longitudinal study investigates whether being overweight or obese at age 8 and 13 years is asso...

    Authors: Deborah Gibson-Smith, Thorhallur I. Halldorsson, Mariska Bot, Ingeborg A. Brouwer, Marjolein Visser, Inga Thorsdottir, Bryndis E. Birgisdottir, Vilmundur Gudnason, Gudny Eiriksdottir, Lenore J. Launer, Tamara B. Harris and Ingibjorg Gunnarsdottir

    Citation: BMC Pediatrics 2020 20:25

    Content type: Research article

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  17. Although there is high prevalence of obesity and other cardiovascular risk factors among Latin American adolescents, there is limited evidence on dietary intake and physical activity (PA) patterns in this popu...

    Authors: Gerson Luis de Moraes Ferrari, Irina Kovalskys, Mauro Fisberg, Georgina Gomez, Attilio Rigotti, Lilia Yadira Cortés Sanabria, Martha Cecilia Yépez García, Rossina Gabriella Pareja Torres, Marianella Herrera-Cuenca, Ioná Zalcman Zimberg, Viviana Guajardo, Michael Pratt, Agatha Nogueira Previdelli, Shaun Scholes, Carlos A. Celis-Morales and Dirceu Solé

    Citation: BMC Pediatrics 2020 20:24

    Content type: Research article

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  18. Uric acid has been identified as an important factor in the development of hypertension. If low birth weight (LBW) combined with catch-up growth (CUG) is associated with continuously elevated serum uric acid l...

    Authors: Bomi Park, Bohyun Park, Hye Ah Lee, Seonhwa Lee, Hyejin Han, Eunae Park, Su Jin Cho, Hae Soon Kim, Young Ju Kim, Eun-Hee Ha and Hyesook Park

    Citation: BMC Pediatrics 2020 20:23

    Content type: Research article

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  19. Tonsillitis, with associated tonsillar hypertrophy, is a common disease of childhood, yet it is rarely associated with sudden death due to airway obstruction. Lethal complications involving the inflamed tonsil...

    Authors: I. Nieuwoudt, P. Goussard, J. Verster and J. Dempers

    Citation: BMC Pediatrics 2020 20:22

    Content type: Case report

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  20. There is considerable evidence that health systems, in so far as they ensure access to healthcare, promote population health even independent of other determinants. Access to child health services remains inte...

    Authors: Edgar Arnold Lungu, Catherine Darker and Regien Biesma

    Citation: BMC Pediatrics 2020 20:20

    Content type: Research article

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  21. Cleidocranial dysplasia (CCD) is a rare skeletal disorder with autosomal dominant inheritance that is characterized by hypoplastic clavicles, delayed closure of the cranial sutures, dental abnormalities, and s...

    Authors: Nozomi Takaki, Jun Mori, Satoshi Matsuo, Toshio Osamura and Toshimi Michigami

    Citation: BMC Pediatrics 2020 20:19

    Content type: Case report

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  22. Lactobacillus spp. play a major role in the development of dental caries. Although effective methods are known for the prevention and management of dental caries, its prevalence of dental caries is increasing amo...

    Authors: Dawit Ademe, Desalegn Admassu and Senthilkumar Balakrishnan

    Citation: BMC Pediatrics 2020 20:18

    Content type: Research article

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  23. Double aneuploidies - especially in combination with structural aberrations - are extremely rare among liveborns. The most frequent association is that of Down (DS) and Klinefelter syndromes (KS). We present t...

    Authors: Eva Pinti, Anna Lengyel, Gyorgy Fekete and Iren Haltrich

    Citation: BMC Pediatrics 2020 20:17

    Content type: Case report

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  24. Fever in childhood is a common acute presentation requiring clinical triage to identify the few children who have serious underlying infection. Clinical practice guidelines (CPGs) have been developed to assist...

    Authors: Joanna Holt, Leslie White, Gavin R. Wheaton, Helena Williams, Shefali Jani, Gaston Arnolda, Hsuen P. Ting, Peter D. Hibbert and Jeffrey Braithwaite

    Citation: BMC Pediatrics 2020 20:16

    Content type: Research article

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  25. Hemophagocytic lymphohistiocytosis (HLH) is an infrequent but life-threatening disease due to excessive immune activation. Secondary HLH can be triggered by infections, autoimmune diseases, and malignant disea...

    Authors: Mitsuru Tsuge, Machiko Miyamoto, Reiji Miyawaki, Yoichi Kondo and Hirokazu Tsukahara

    Citation: BMC Pediatrics 2020 20:15

    Content type: Case report

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  26. Rapid magnetic resonance imaging (MRI) protocols may be effective in the emergency department (ED) to evaluate nontraumatic neurologic complaints. We evaluate neuroimaging (rapid MRI [rMRI]), head computerized...

    Authors: Sriram Ramgopal, Sabrina A. Karim, Subramanian Subramanian, Andre D. Furtado and Jennifer R. Marin

    Citation: BMC Pediatrics 2020 20:14

    Content type: Research article

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  27. Most Australian Aboriginal children are on track with their development, however, the prevalence of children at risk of or with a developmental or behavioural problem is higher than in other children. Aborigin...

    Authors: Shingisai Chando, Jonathan C. Craig, Leonie Burgess, Simone Sherriff, Alison Purcell, Hasantha Gunasekera, Sandra Banks, Natalie Smith, Emily Banks and Sue Woolfenden

    Citation: BMC Pediatrics 2020 20:13

    Content type: Research article

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  28. Muscle contractures are developing during childhood and may cause extensive problems in gait and every day functioning in children with cerebral palsy (CP). The aim of the present study was to evaluate how the...

    Authors: Merete Aarsland Fosdahl, Reidun Jahnsen, Are Hugo Pripp and Inger Holm

    Citation: BMC Pediatrics 2020 20:11

    Content type: Research article

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  29. Adverse birth outcome which attributes to most perinatal deaths is an important indicator of child health and survival. Hence, this study aims to identify determinants of adverse birth outcome among mothers wh...

    Authors: Helen Tsehaye Hailemichael, Gurmesa Tura Debelew, Haileselasie Berhane Alema, Meresa Gebremedhin Weldu and Kebede Haile Misgina

    Citation: BMC Pediatrics 2020 20:10

    Content type: Research article

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  30. Cerebral palsy (CP) is frequently associated with specific cognitive impairments, such as executive dysfunction which are related to participation and quality of life (QOL). The proposed study will examine whe...

    Authors: María García-Galant, Montse Blasco, Lee Reid, Kerstin Pannek, David Leiva, Olga Laporta-Hoyos, Júlia Ballester-Plané, Júlia Miralbell, Xavi Caldú, Xènia Alonso, Esther Toro-Tamargo, Mar Meléndez-Plumed, Francisca Gimeno, Marc Coronas, Emili Soro-Camats, Roslyn Boyd…

    Citation: BMC Pediatrics 2020 20:9

    Content type: Study protocol

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  31. Perinatal decision-making affects outcomes for extremely preterm babies (22–26 weeks’ gestational age (GA)): more active units have improved survival without increased morbidity. We hypothesised such units may...

    Authors: Andrei Scott Morgan, Babak Khoshnood, Caroline Diguisto, Laurence Foix L’Helias, Laetitia Marchand-Martin, Monique Kaminski, Jennifer Zeitlin, Gérard Bréart, François Goffinet and Pierre-Yves Ancel

    Citation: BMC Pediatrics 2020 20:8

    Content type: Research Article

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  32. The aim of this study is to contribute to the knowledge base on the long-term outcomes of evidence-based medical interventions used to improve gross motor function in children and adolescents with Cerebral Palsy.

    Authors: Jane Valentine, Sue-Anne Davidson, Natasha Bear, Eve Blair, Lisa Paterson, Roslyn Ward, David Forbes and Catherine Elliott

    Citation: BMC Pediatrics 2020 20:7

    Content type: Research article

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  33. Pain is a common experience in adolescence, with up to 44% of adolescents reporting chronic pain. For a significant minority, severe pain becomes an ongoing disabling problem. Treatment of adolescent chronic p...

    Authors: Abbie Jordan, Fiona M. Begen, Lisa Austin, Rhiannon T. Edwards and Hannah Connell

    Citation: BMC Pediatrics 2020 20:6

    Content type: Research article

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  34. Measles is a recurrent health problem in both advanced and developed countries. The World Health Organization (WHO) recommends anti-measles immunoglobulin M (Ig M) as the standard method of detecting the virus...

    Authors: Dominicus Husada, Kusdwijono, Dwiyanti Puspitasari, Leny Kartina, Parwati Setiono Basuki and Ismoedijanto

    Citation: BMC Pediatrics 2020 20:5

    Content type: Research article

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  35. The aim of the current study was to examine the relationship between anthropometric characteristics (i.e. body height, body weight, body mass index [BMI] and waist circumference [WC]) with motor performance ab...

    Authors: Sascha W. Hoffmann, Matthias Dreher, Michael S. Urschitz and Perikles Simon

    Citation: BMC Pediatrics 2020 20:4

    Content type: Research article

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  36. The high HIV prevalence in South Africa may potentially be shaping the local adverse drug reaction (ADR) burden. We aimed to describe the prevalence and characteristics of serious ADRs at admission, and during...

    Authors: Johannes P. Mouton, Melony C. Fortuin-de Smidt, Nicole Jobanputra, Ushma Mehta, Annemie Stewart, Reneé de Waal, Karl-Günter Technau, Andrew Argent, Max Kroon, Christiaan Scott and Karen Cohen

    Citation: BMC Pediatrics 2020 20:3

    Content type: Research article

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  37. Early diagnosis and treatment are improving significantly the quality of life of patients with cystic fibrosis (CF). This recessive disease is caused by a great variability of mutations in the CF transmembrane...

    Authors: Joana Rosa, Patrícia Gaspar-Silva, Paula Pacheco, Conceição Silva, Cláudia C. Branco, Barbara S. Vieira, Alexandra Carreiro, Juan Gonçalves and Luisa Mota-Vieira

    Citation: BMC Pediatrics 2020 20:2

    Content type: Research article

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  38. Choice of insulin delivery for type 1 diabetes can be difficult for many parents and children. We evaluated decision coaching using a patient decision aid for helping youth with type 1 diabetes and parents dec...

    Authors: Margaret L. Lawson, Allyson L. Shephard, Bryan Feenstra, Laura Boland, Nadia Sourial and Dawn Stacey

    Citation: BMC Pediatrics 2020 20:1

    Content type: Research article

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  39. Positional deformities (PD) are common during early infancy. Severe cases may result in facial abnormalities and be associated with delayed neurological development in infants. The earlier the detection of PD,...

    Authors: Wang Yang, Jianping Chen, Wenzhi Shen, Chengju Wang, Zhifeng Wu, Qing Chang, Wenzao Li, Kuilin Lv, Qiuming Pan, Hongxia Li, Duyao Ha and Yuping Zhang

    Citation: BMC Pediatrics 2019 19:520

    Content type: Research article

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  40. Bacterial meningitis (BM) is a serious, life-threatening infectious disease of the central nervous system that often occurs in young children. The most common severe to moderate sequelae following BM are senso...

    Authors: O. El Tahir, R. C. J. de Jonge, S. Ouburg, S. A. Morré and A. M. van Furth

    Citation: BMC Pediatrics 2019 19:519

    Content type: Study protocol

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  41. Undernutrition poses a serious health challenge in developing countries and Tanzania has the highest undernutrition burden of Eastern and Southern Africa. Poor infant and young child feeding practices have bee...

    Authors: Ahmed Gharib Khamis, Akwilina Wendelin Mwanri, Julius Edward Ntwenya and Katharina Kreppel

    Citation: BMC Pediatrics 2019 19:518

    Content type: Research article

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  42. Given its narrow therapeutic range, digoxin’s pharmacokinetic parameters in infants are difficult to predict due to variation in birth weight and gestational age, especially for critically ill newborns. There ...

    Authors: Shu-Hui Yao, Hsiang-Te Tsai, Wen-Lin Lin, Yu-Chieh Chen, Chiahung Chou and Hsiang-Wen Lin

    Citation: BMC Pediatrics 2019 19:517

    Content type: Research article

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  43. Gynecomastia develops due to the reversed estradiol-to-Testosterone ratio in adolescence, and symptoms typically improve within 2 years. The causes vary widely, including estrogen excess and tumors, and surgic...

    Authors: Jung-Eun Moon, Cheol Woo Ko, Jung Dug Yang and Joon Seok Lee

    Citation: BMC Pediatrics 2019 19:515

    Content type: Case report

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  44. Isolated sulfite oxidase deficiency (ISOD) is an autosomal recessive disorder caused by a deficiency of sulfite oxidase, which is encoded by the sulfite oxidase gene (SUOX). Clinically, the disorder is classified...

    Authors: Maoqiang Tian, Yi Qu, Lingyi Huang, Xiaojuan Su, Shiping Li, Junjie Ying, Fengyan Zhao and Dezhi Mu

    Citation: BMC Pediatrics 2019 19:510

    Content type: Case report

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