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  1. End-of-life decisions with potential life-shortening effect in neonates and infants are common. We aimed to evaluate how often and in what manner neonatologists consult with parents and other healthcare provid...

    Authors: Laure Dombrecht, Filip Cools, Joachim Cohen, Luc Deliens, Linde Goossens, Gunnar Naulaers, Kim Beernaert and Kenneth Chambaere
    Citation: BMC Pediatrics 2022 22:597
  2. Advances in genetic and pharmaceutical technology and pediatric care have enabled treatment options for an increasing number of rare diseases in affected children. However, as current treatment options are pri...

    Authors: Silke Wiegand-Grefe, Anna Liedtke, Lydia Morgenstern, Antonia Hoff, Anikó Csengoe-Norris, Jessika Johannsen, Jonas Denecke, Claus Barkmann, Benjamin Grolle, Anne Daubmann, Karl Wegscheider and Johannes Boettcher
    Citation: BMC Pediatrics 2022 22:596
  3. Parents of children who are diagnosed with a poor-prognosis cancer want to be involved in making treatment-related decisions for their child. They often make repeated decisions depending on their child’s respo...

    Authors: Helen Pearson H, Gemma Bryan, Catherine Kayum, Faith Gibson and Anne-Sophie Darlington
    Citation: BMC Pediatrics 2022 22:595
  4. Effective triage at hospitals can improve outcomes for children globally by helping identify and prioritize care for those most at-risk of death. Paper-based pediatric triage guidelines have been developed to ...

    Authors: Stefanie K Novakowski, Olive Kabajaasi, Mai-Lei Woo Kinshella, Yashodani Pillay, Teresa Johnson, Dustin Dunsmuir, Katija Pallot, Jessica Rigg, Nathan Kenya-Mugisha, Bernard Toliva Opar, J Mark Ansermino, Abner Tagoola and Niranjan Kissoon
    Citation: BMC Pediatrics 2022 22:593
  5. To discuss the clinical and prognostic indicators of pediatric malignant rhabdoid tumor of the kidney (MRTK), and to increase the understanding of the occurrence and development of MRTK.

    Authors: Chenghao Zhanghuang, Zhaoxia Zhang, Li Zeng, Bing Yan, Haoyu Tang, Jinkui Wang, Xing Liu, Guanghui Wei and Dawei He
    Citation: BMC Pediatrics 2022 22:591
  6. Vitamin and mineral supplements are widely used by children and adults diagnosed with autism spectrum disorder (ASD). Several studies have reported benefits of such supplements in resolving nutritional deficie...

    Authors: James B. Adams, Jasmine Kirby, Tapan Audhya, Paul Whiteley and Jaclyn Bain
    Citation: BMC Pediatrics 2022 22:590
  7. Ligase IV (LIG4) dificiency is a very rare clinical syndrome with around 50 cases reported to date. This syndrome is caused by biallelic pathogenic variants in the LIG4 gene, which cause DNA damage repair diso...

    Authors: Miao Huang, Guoqing Dong, Xiyan Lu, Fei Xiao, Qixin Zhou and Shaoyi Zhang
    Citation: BMC Pediatrics 2022 22:588
  8. Individuals with Fetal Alcohol Spectrum Disorder (FASD) are at risk of having adverse childhood experiences (ACEs), especially those with child protection and/or justice system involvement. The complex relatio...

    Authors: Grace Kuen Yee Tan, Martyn Symons, James Fitzpatrick, Sophia G. Connor, Donna Cross and Carmela F. Pestell
    Citation: BMC Pediatrics 2022 22:587
  9. Children with low birth weight (LBW) are at risk of linear growth faltering and developmental deficits. Evidence suggests that early child stimulation and care reflected as responsive caregiving and opportunit...

    Authors: Ravi Prakash Upadhyay, Sunita Taneja, Tor A. Strand, Halvor Sommerfelt, Mari Hysing, Sarmila Mazumder, Nita Bhandari, Jose Martines, Tarun Dua, Patricia Kariger and Rajiv Bahl
    Citation: BMC Pediatrics 2022 22:586
  10. Childhood obesity has become a major public health problem for both developed and developing nations. It is uncommon to find under-nutrition in many low and middle-income countries; as well, obesity is a doubl...

    Authors: Belete Achamyelew Ayele, Sofonyas Abebaw Tiruneh, Asnakew Achaw Ayele, Melkamu Aderajew Zemene, Ermias Sisay Chanie and Habtamu Shimels Hailemeskel
    Citation: BMC Pediatrics 2022 22:585
  11. The size of the anterior visual pathway (AVP) structures is affected by patient age and pathology. Normative data is useful when determining whether pathology is present. AVP structures do not respect the stan...

    Authors: Stefan Markart, Simon Wildermuth, Johannes Geiss, Erik P. Willems, Veit Sturm, Michael Ditchfield and Stephan Waelti
    Citation: BMC Pediatrics 2022 22:584
  12. Human adenovirus (HAdV) is an important viral agent in children which can lead to severe acute respiratory infection (SARI). Reports on molecular epidemiology of HAdVs in Iran are limited. This case-control st...

    Authors: Sevrin Zadheidar, Jila Yavarian, Zahra Heydarifard, Ahmad Nejati, Kaveh Sadeghi, Nastaran Ghavami, Simin Abbasi, Somayeh Shatizadeh Malekshahi, Talat Mokhtari-Azad and Nazanin-Zahra Shafiei-Jandaghi
    Citation: BMC Pediatrics 2022 22:583
  13. Malnutrition or insufficient physical activity (PA) is a risk factor for obesity and chronic disease in children and adolescents. Affected by different economic circumstance, ethnic, dietary behavior, physical...

    Authors: He Liu, Cunjian Bi, Hongniu Lin, Wei Ma, Jie Zhang, Yan-Yan Hu and Jing-Zhi Liu
    Citation: BMC Pediatrics 2022 22:582
  14. Optimal nutrition during the first two years of a child’s life is critical for the reduction of morbidity and mortality. In Ghana, majority of children miss out on optimal nutrition and only few (13%) of child...

    Authors: Christiana Nsiah-Asamoah, George Adjei, Samuel Agblorti and David Teye Doku
    Citation: BMC Pediatrics 2022 22:581
  15. Our aim was to evaluate infant behavioral state, stool microbiome profile and calprotectin in infants with infantile colic receiving a partially hydrolyzed protein formula with or without added Lacticaseibacillus...

    Authors: Robert J. Shulman, Maciej Chichlowski, Fabiola Gutierrez Orozco, Cheryl L. Harris, Jennifer L. Wampler, Nicholas A. Bokulich and Carol Lynn Berseth
    Citation: BMC Pediatrics 2022 22:580
  16. Early sleep problems co-occur with crying, eating problems, and parental distress. This study investigates the impact of a parent-focused intervention to improve child sleep with the following aims: (1) To ass...

    Authors: Marisa Schnatschmidt, Friederike Lollies and Angelika A. Schlarb
    Citation: BMC Pediatrics 2022 22:578
  17. Osteogenesis imperfecta (OI) causes a number of abnormalities in somatic development. The predominant symptoms are reduced bone mass and an increased risk of fractures as well as bone deformities and short sta...

    Authors: E. Jakubowska-Pietkiewicz, A. Maćkowska, J. Nowicki, E. Woźniak and Nowicki Jakub
    Citation: BMC Pediatrics 2022 22:577
  18. Malnutrition associated with HIV infection is a complex condition, with HIV-positive children having a higher mortality rate than HIV-negative children, resulting in significant morbidity and mortality in chil...

    Authors: Chalie Marew Tiruneh, Tigabu Desie Emiru, Nigusie Selomon Tibebu, Moges Wubneh Abate, Adane Birhanu Nigat, Berihun Bantie, Agimasie Tigabu, Amsalu Belete, Belete Gelaw Walle and Getasew Legas
    Citation: BMC Pediatrics 2022 22:575
  19. The present study investigated the relationship between a health-promoting lifestyle and menstrual pain intensity and distress among adolescent girls in Qazvin.

    Authors: Elahe Cholbeigi, Shaghayegh Rezaienik, Narges Safari, Kerrie Lissack, Mark D Griffiths and Zainab Alimoradi
    Citation: BMC Pediatrics 2022 22:574
  20. The advent of highly-active anti-retroviral therapy (HAART) has resulted in the survival of children with Human Immunodeficiency Virus (HIV)/Acquired Immune Deficiency Syndrome (AIDS) into adolescence. Their p...

    Authors: Chibuzo O Ndiokwelu, Samuel N Uwaezuoke and Kenechukwu K Iloh
    Citation: BMC Pediatrics 2022 22:573
  21. In our prior study of 643 children, ages 4–11 years, children with pet dogs had lower anxiety scores than children without pet dogs. This follow-up study examines whether exposure to pet dogs or cats during ch...

    Authors: Anne Gadomski, Melissa B. Scribani, Nancy Tallman, Nicole Krupa, Paul Jenkins and Lawrence S. Wissow
    Citation: BMC Pediatrics 2022 22:572
  22. IgA vasculitis (IgAV) is the most common form of systemic vasculitis in childhood and frequently involves the kidney. A minority of patients with IgA vasculitis nephritis (IgAVN), especially those presenting w...

    Authors: Sarina Butzer, Imke Hennies, Charlotte Gimpel, Jutta Gellermann, Gesa Schalk, Sabine König, Anja K. Büscher, Anja Lemke and Martin Pohl
    Citation: BMC Pediatrics 2022 22:570
  23. We tend to investigate the connection between time to appropriate therapy (TTAT) and prognosis in pediatric patients with nosocomial Klebsiella pneumoniae (K. pneumoniae) bloodstream infection, and find the optim...

    Authors: Jie Cheng, Qinyuan Li, Guangli Zhang, Huiting Xu, Yuanyuan Li, Xiaoyin Tian, Dapeng Chen and Zhengxiu Luo
    Citation: BMC Pediatrics 2022 22:568
  24. Pediatric applications of non-invasive brain stimulation using transcranial direct current stimulation (tDCS) have demonstrated its safety with few adverse events reported. Remotely monitored tDCS, as an adjuv...

    Authors: Emma A. Simpson, Catarina Saiote, Ellen Sutter, Daniel H. Lench, Chrysanthy Ikonomidou, Melissa A. Villegas and Bernadette T. Gillick
    Citation: BMC Pediatrics 2022 22:566
  25. A complication of elective cesarean section (CS) delivery is its interference with the normal intestinal colonization of the infant, affecting the immune and metabolic signaling in early life— a process that h...

    Authors: Noora Carpén, Petter Brodin, Willem M. de Vos, Anne Salonen, Kaija-Leena Kolho, Sture Andersson and Otto Helve
    Citation: BMC Pediatrics 2022 22:565
  26. Recognizing the level of glycemic control of a client is an important measure/tool to prevent acquiring complications and risk of death from diabetes. However, the other most important variable, which is the t...

    Authors: Fentahun Meseret, Amare Belachew, Getasew Tesfa, Teshale Mengesha, Tsegasew Embiale, Ayichew Alemu and Melsew Dagne
    Citation: BMC Pediatrics 2022 22:563
  27. Maternal education is one of the main ways to improve children's nutritional behaviors and development. The purpose of this study is to investigate the effect of educational intervention based on Health Belief...

    Authors: Ali Khani Jeihooni, Fatemeh Mohammadkhah, Fatemeh Razmjouie, Pooyan Afzali Harsini and Fariba Sedghi Jahromi
    Citation: BMC Pediatrics 2022 22:561
  28. The 5-minute APGAR score is clinically used as a screening tool to assess how the newborn has reacted to previous care, remaining relevant for predicting neonatal survival. This study aimed to analyze the dete...

    Authors: Victória Brioso Tavares, Josiel de Souza e Souza, Márcio Vinicius de Gouveia Affonso, Emerson Souza Da Rocha, Lucio Flavio Garcia Rodrigues, Luciana de Fátima da Costa Moraes, Gabrielly Cristiny dos Santos Coelho, Sabrina Souza Araújo, Pablo Fabiano Moura das Neves, Fabiana de Campos Gomes and João Simão de Melo-Neto
    Citation: BMC Pediatrics 2022 22:560
  29. Neurally adjusted ventilatory assist is an emerging mode of respiratory support that uses the electrical activity of the diaphragm (Edi) to provide synchronised inspiratory pressure support, proportional to an...

    Authors: Varappriyangga Gurumahan, Sriganesh Thavalingam, Tim Schindler, John Smyth, Kei Lui and Srinivas Bolisetty
    Citation: BMC Pediatrics 2022 22:559
  30. A lack of adequate dietary knowledge may result in poor health. The purpose of this study was to study the association between dietary knowledge and overweight/obesity in children and adolescents. 

    Authors: Lihong Wang, Jielian Zhuang, Heng Zhang and Weijuan Lu
    Citation: BMC Pediatrics 2022 22:558
  31. Salmonella gastroenteritis causes significant morbidity among pediatric patients, mainly in developing world, such as the Middle East and North Africa (MENA) region. Concurrently, data from MENA countries like Ir...

    Authors: Akram Rezaei, Farhad B. Hashemi, Roya Rasooly Heshteli, Maryam Rahmani and Shahnaz Halimi
    Citation: BMC Pediatrics 2022 22:557
  32. Although self-limiting viral infections are predominant, children with acute infections are often prescribed antibiotics by family physicians. The aim of the study is to evaluate the impact of two intervention...

    Authors: Zane Likopa, Anda Kivite-Urtane, Vija Silina and Jana Pavare
    Citation: BMC Pediatrics 2022 22:556
  33. Autonomy is recognized as important for individual well-being and constitutes one dimension in the KIDSCREEN-instrument measuring health related quality of life (HRQoL) in children and adolescents. However, th...

    Authors: Mårten Eriksson, Eva Boman and Pia Svedberg
    Citation: BMC Pediatrics 2022 22:555
  34. Bacterial infection of adenoid is currently considered to be an important cause of adenoid hypertrophy (AH) in children. Although several bacteriology studies on adenoid diseases have been reported, the aerobi...

    Authors: Lujie Zuo, Li He, Aiping Huang, Yingying Liu, Aiying Zhang, Li Wang, Yingluan Song and Jiangqiao Geng
    Citation: BMC Pediatrics 2022 22:553
  35. To explore the prevalence, outcome and perinatal risks of neonatal hypoxemic respiratory failure (NRF) in a survey of all livebirths from a regional network of perinatal-neonatal care during the transition per...

    Authors: Sufang Ding, Yaling Xu, Hui Wang, Hongni Yue, Zhaojun Pan and Bo Sun
    Citation: BMC Pediatrics 2022 22:552
  36. The first Covid-19 pandemic affected the epidemiology of several diseases. A general reduction in the emergency department (ED) accesses was observed during this period, both in adult and pediatric contexts.

    Authors: Laura Cesca, Ester Conversano, Federica Alessandra Vianello, Laura Martelli, Chiara Gualeni, Francesca Bassani, Milena Brugnara, Giulia Rubin, Mattia Parolin, Mauro Anselmi, Mara Marchiori, Gianluca Vergine, Elisabetta Miorin, Enrico Vidal, Cristina Milocco, Cecilia Orsi…
    Citation: BMC Pediatrics 2022 22:550
  37. Sickle cell disease (SCD) is associated with an increased risk of cardiovascular disease that may be due to a variety of possible risk factors, including abnormal blood pressure. Blood pressure (BP) of childre...

    Authors: Juan C. Kupferman, Janet E. Rosenbaum, Marc B. Lande, Stella Stabouli, Yongsheng Wang, Daniella Forman, Dimitrios I. Zafeiriou and Steven G. Pavlakis
    Citation: BMC Pediatrics 2022 22:549

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