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  1. In Ethiopia, about 57% of child mortality is associated with acute malnutrition in which the burden is dominant at the rural community. In that regard, the Ethiopian government has been implementing the Outpat...

    Authors: Getachew Teshale, Ayal Debie, Endalkachew Dellie and Tsegaye Gebremedhin
    Citation: BMC Pediatrics 2022 22:374
    Content type: Original research Published on:

  2. Screening of critical congenital heart disease (CCHD) using pulse oximetry is a routine procedure in many countries, but not in Indonesia. This study aimed to evaluate the feasibility of implementing CCHD scre...

    Authors: Indah K. Murni, Tunjung Wibowo, Nadya Arafuri, Vicka Oktaria, Lucia K. Dinarti, Dicky Panditatwa, Linda Patmasari, Noormanto Noormanto and Sasmito Nugroho
    Citation: BMC Pediatrics 2022 22:369
    Content type: Research Published on:

  3. Sickle cell anemia (SCA) is the leading cause of childhood stroke. We aimed to evaluate whether altered cerebral flow velocities, as measured by transcranial Doppler (TCD), are associated with vaso-occlusive c...

    Authors: Gabriel Pinheiro Modolo, Gustavo José Luvizutto, Pedro Tadao Hamamoto Filho, Gabriel Pereira Braga, Silmeia Garcia Zanati Bazan, Natalia Cristina Ferreira, Juli Thomaz de Souza, Fernanda Cristina Winckler, Carlos Clayton Macedo de Freitas, Newton Key Hokama, Edison Iglesias de Oliveira Vidal and Rodrigo Bazan
    Citation: BMC Pediatrics 2022 22:368
    Content type: Research Published on:

  4. Severe neonatal jaundice can result in long term morbidities and mortality when left untreated. Phototherapy is the main-stay intervention for treating moderate jaundice and for prevention of the development o...

    Authors: Mai-Lei Woo Kinshella, Sangwani Salimu, Brandina Chiwaya, Felix Chikoti, Lusungu Chirambo, Ephrida Mwaungulu, Mwai Banda, Tamanda Hiwa, Marianne Vidler, Elizabeth M. Molyneux, Queen Dube, Joseph Mfutso-Bengo, David M. Goldfarb, Kondwani Kawaza and Alinane Linda Nyondo-Mipando
    Citation: BMC Pediatrics 2022 22:367
    Content type: Research Published on:

  5. Individual differences in children eating behaviours have been linked with childhood overweight and obesity. The determinants of childhood eating behaviours are influenced by a complex combination of hereditar...

    Authors: Anna Delahunt, Marie C. Conway, Eileen C. O’Brien, Aisling A. Geraghty, Linda M. O’Keeffe, Sharleen L. O’Reilly, Ciara M. McDonnell, Patricia M. Kearney, John Mehegan and Fionnuala M. McAuliffe
    Citation: BMC Pediatrics 2022 22:366
    Content type: Research Published on:

  6. Paediatric early warning systems (PEWS) alert health professionals to signs of a child’s deterioration with the intention of triggering an urgent review and escalating care. They can reduce unplanned critical ...

    Authors: Bernie Carter, Holly Saron, Sarah Siner, Jennifer Preston, Matthew Peak, Fulya Mehta, Steven Lane, Caroline Lambert, Dawn Jones, Hannah Hughes, Jane Harris, Leah Evans, Sarah Dee, Chin-Kien Eyton-Chong, Gerri Sefton and Enitan D. Carrol
    Citation: BMC Pediatrics 2022 22:365
    Content type: Research Published on:

  7. Acute lower respiratory tract infection (ALRTI) in children under 5 years is known to be predominantly caused by respiratory syncytial virus (RSV). In recent times, however, human metapneumovirus (HMPV) has al...

    Authors: Anna Aba Kafintu-Kwashie, Nicholas Israel Nii-Trebi, Evangeline Obodai, Margaret Neizer, Theophilus Korku Adiku and John Kofi Odoom
    Citation: BMC Pediatrics 2022 22:364
    Content type: Research Published on:

  8. Nutritional deficiency soon after birth is a risk factor of chronic lung disease (bronchopulmonary dysplasia, BPD). Afflicted infants are further prone to inadequate growth during hospitalization (extrauterine...

    Authors: Lian Wang, Xin-Zhu Lin, Wei Shen, Fan Wu, Jian Mao, Ling Liu, Yan-Mei Chang, Rong Zhang, Xiu-Zhen Ye, Yin-Ping Qiu, Li Ma, Rui Cheng, Hui Wu, Dong-Mei Chen, Ling Chen, Ping Xu…
    Citation: BMC Pediatrics 2022 22:363
    Content type: Research Published on:

  9. Preterm infants have a low level of bone mineralization compared to those born at term, since 80% of calcium incorporation occurs at the end of pregnancy. The purpose of the present study was to investigate th...

    Authors: Galaad Torró-Ferrero, Francisco Javier Fernández-Rego, María Rosario Jiménez-Liria, Juan Jose Agüera-Arenas, Jessica Piñero-Peñalver, María del Mar Sánchez-Joya, María Jesús Fernández-Berenguer, Mónica Rodríguez-Pérez and Antonia Gomez-Conesa
    Citation: BMC Pediatrics 2022 22:362
    Content type: Research Published on:

  11. Children with neurological impairment may have dysphagia and/or gastro-esophageal reflux disease (GERD), which predispose to complications affecting the airways, increasing risk for aspiration-induced acute an...

    Authors: S Fiori, RT Scaramuzzo, E Moretti, C Amador, T Controzzi, A Martinelli, L Filippi, A Guzzetta and L Gargagni
    Citation: BMC Pediatrics 2022 22:360
    Content type: Study protocol Published on:

  12. Febrile seizures are the commonest type of seizure in occurring in the first few years of life, mostly affecting children aged six months to five years old. While largely benign, the incidence of each febrile ...

    Authors: Rana Sawires, Martin Kuldorff, Michael Fahey, Hazel Clothier and Jim Buttery
    Citation: BMC Pediatrics 2022 22:359
    Content type: Research Published on:

  13. Several socio-demographic characteristics are associated with complications following certain pediatric surgical procedures. In this comprehensive study, we sought to determine socio-demographic risk factors a...

    Authors: Robert Brock, Angel Chu, Shengjie Lu, Mary Elizabeth Brindle and Ranjani Somayaji
    Citation: BMC Pediatrics 2022 22:358
    Content type: Research Published on:

  14. Otitis media with effusion (OME) is common in children aged between 6 months to 4 years, and it is one of the causes of hearing loss (HL) in children worldwide. OME is a type of inflammation of the middle ear ...

    Authors: Kabagambe Bamaraki, Justine Namwagala, Rym Hidour and Emma Nsalazi Bambi
    Citation: BMC Pediatrics 2022 22:357
    Content type: Research Published on:

  15. Neonatal phototherapy (NNPT) has long been used as an effective and relatively safe method of treating neonatal hyperbilirubinemia. Considering the subsequent evidence of long-term impacts of NNPT such as mali...

    Authors: Fatemeh Sabzevari, Reza Sinaei, Bahareh Bahmanbijari, Simin Dehghan Krooki and Azam Dehghani
    Citation: BMC Pediatrics 2022 22:356
    Content type: Research Published on:

  16. We investigated the age of starting Estrogen replacement therapy as a key parameter for reaching near normal Final Height (FH) in Chronic Kidney Disease (CKD) girls with growth retardation.

    Authors: Davoud Amirkashani, Farzaneh Rohani, Mahmoud Khodadost, Rozita Hoseini, Hamidreza Alidoost and Sedigheh Madani
    Citation: BMC Pediatrics 2022 22:355
    Content type: Research Published on:

  17. Transient tachypnea of the newborn (TTN), as a common cause of neonatal respiratory distress, needs to be distinguished from respiratory distress syndrome (RDS). Various modalities such as lung ultrasonography...

    Authors: So Jin Yoon, Jung Ho Han, Kee Hyun Cho, Joonsik Park, Soon Min Lee and Min Soo Park
    Citation: BMC Pediatrics 2022 22:354
    Content type: Research Published on:

  18. Kawasaki disease (KD) is a self-limiting vasculitis with an unknown etiology. It has been reported that breastfeeding has a potential protective effect on KD development. However, whether breastfeeding has an ...

    Authors: Hongli Wang, Yunjia Tang, Wenhua Yan, Qiuqin Xu, Xuan Li and Weiguo Qian
    Citation: BMC Pediatrics 2022 22:353
    Content type: Research Published on:

  19. Atopic dermatitis (AD) is the most common chronic inflammatory skin condition in childhood. Most (50-60%) children with AD report sleep disturbance, which is secondary to itch, dry skin, inflammation, and abno...

    Authors: Cathal O’Connor, Alan D. Irvine, Deirdre Murray, Michelle Murphy, Jonathan O’B Hourihane and Geraldine Boylan
    Citation: BMC Pediatrics 2022 22:352
    Content type: Study protocol Published on:

  20. The aim of this study was to evaluate the serum level of matrix metalloproteinase 7 (MMP7) in infants with cholestasis and the diagnostic values of this biomarker to differentiate biliary atresia (BA) from oth...

    Authors: Pejman Rohani, Seyyed Bahador Mirrahimi, Haleh Bashirirad, Parisa Rahmani, Niyoosha Kamran, Hosein Alimadadi, Mahmoud Hajipour and Mohammad Hassan Sohouli
    Citation: BMC Pediatrics 2022 22:351
    Content type: Research Published on:

  21. Neonatal exposure to episodic hypoxemia and hyperoxemia is highly relevant to outcomes. Our goal was to investigate the differences in the frequency and duration of extreme low and high SpO2 episodes between auto...

    Authors: Thomas E. Bachman, Wes Onland, Anton H. van Kaam, Karel Roubik, Helmut D. Hummler, Mithilesh Lal, Gianluca Lista and Carlos A. Fajardo
    Citation: BMC Pediatrics 2022 22:350
    Content type: Research Published on:

  22. Isolated steroid-resistant nephrotic syndrome (ISRNS) is caused by mutations in the Wilms’ tumor-1 (WT1) gene, which encodes glomerular podocytes and podocyte slit diaphragm.We report a novel 8-year-old female...

    Authors: Yiyang Li, Chuan Tian, Yajun Wang, Guoda Ma and Riling Chen
    Citation: BMC Pediatrics 2022 22:349
    Content type: Case report Published on:

  23. Congenital heart disease (CHD) is the most common congenital defect in neonates. Infants with CHD often have more nutritional difficulties, but currently, there is no unified Food Frequency Questionnaire (FFQ)...

    Authors: Yiling Lei, Yang Liu, Chunmei Hu, Yanqin Cui, Rui Gao, Xiuxiu Li and Yanna Zhu
    Citation: BMC Pediatrics 2022 22:348
    Content type: Research article Published on:

  24. Overweight and obesity are major public health crises among children and adolescents and contribute to a significant economic burden. We aimed to investigate the relationship between breastfeeding duration and...

    Authors: Fange Liu, Di Lv, Lumin Wang, Xiaoyu Feng, Rongjun Zhang, Wendong Liu and Wenchao Han
    Citation: BMC Pediatrics 2022 22:347
    Content type: Research Published on:

  25. To explore parents’ perceptions of an upper extremity (UE) intervention using functional electrical stimulation (FES) for young children with hemiparesis.

    Authors: Emma Swaffield, Jaynie F. Yang, Patricia Manns, Katherine Chan and Kristin E. Musselman
    Citation: BMC Pediatrics 2022 22:346
    Content type: Research Published on:

  26. Neonatal Opioid Withdrawal Syndrome (NOWS) is a significant public health issue and while millions of neonates are affected each year, an optimal pharmacologic weaning protocol has yet to be demonstrated. In t...

    Authors: Mary Beth Sutter, Hannah Watson, Nicole Yonke, Sherry Weitzen and Lawrence Leeman
    Citation: BMC Pediatrics 2022 22:345
    Content type: Research Published on:

  27. Iron overload (IO) is a complication in transfusion dependent beta thalassaemia (TDT). Pathogenic variants in genes involving iron metabolism may confer increased risk of IO. The objective of this study was to...

    Authors: Ruwangi Dissanayake, Nayana Samarasinghe, Samantha Waidyanatha, Sajeewani Pathirana, Nilaksha Neththikumara, Vajira H. W. Dissanayake, Kalum Wetthasinghe, Lallindra Gooneratne and Pujitha Wickramasinghe
    Citation: BMC Pediatrics 2022 22:344
    Content type: Research Published on:

  29. The practice of eating together, commensality, is rarely explored in the context of childhood obesity treatment. This is noteworthy given long-standing debates about the physical, psychosocial, and societal benef...

    Authors: Nicklas Neuman, Anna Jörnvi, Anna Ek, Karin Nordin, Karin Eli and Paulina Nowicka
    Citation: BMC Pediatrics 2022 22:342
    Content type: Research Published on:

  30. Mortality at a young age is key to public health measures. This study aims to describe the burden, trend, and associated factors of under-five mortality rate (U5MR) in Zambia from 2007-to-2018.

    Authors: Amanuel Kidane Andegiorgish, Henok G. Woldu, Mohamed Elhoumed, Zhonghai Zhu and Lingxia Zeng
    Citation: BMC Pediatrics 2022 22:341
    Content type: Research Published on:

  31. We investigated risk factors for sustained virological non-suppression (viral load ≥ 1000 copies/ml on two tests 48 weeks apart) among children and adolescents accessing HIV care in public sector clinics in Ha...

    Authors: Christi Jackson, Andrea M. Rehman, Grace McHugh, Carmen Gonzalez-Martinez, Lucky G. Ngwira, Tsitsi Bandason, Hilda Mujuru, Jon O. Odland, Elizabeth L. Corbett, Rashida A. Ferrand and Victoria Simms
    Citation: BMC Pediatrics 2022 22:340
    Content type: Research Published on:

  32. Obesity is considered to be one of the most important factors reducing the sense of happiness and satisfaction with life, especially among women. This belief already exists in middle childhood, as the preschoo...

    Authors: Małgorzata Lipowska, Mariusz Lipowski, Natasza Kosakowska-Berezecka, Dorota Dykalska, Ariadna Łada-Maśko and Bernadetta Izydorczyk
    Citation: BMC Pediatrics 2022 22:339
    Content type: Research Published on:

  33. In The Netherlands, prematurely born infants and their parents are offered regular developmental check-ups in a hospital setting. In line with providing healthcare at distance, the use of video footage showing...

    Authors: I. Suir, J. Oosterhaven, M. Boonzaaijer, J. Nuysink and M. Jongmans
    Citation: BMC Pediatrics 2022 22:338
    Content type: Research Published on:

  34. Dating abuse (DA) is prevalent and consequential, but no brief DA screening tools are available for use in pediatric or other settings. This study was designed to determine the sensitivity, specificity, and pr...

    Authors: Emily F. Rothman, Julia K. Campbell, Ariel M. Hoch, Megan Bair-Merritt, Carlos A. Cuevas, Bruce Taylor and Elizabeth A. Mumford
    Citation: BMC Pediatrics 2022 22:337
    Content type: Original research Published on:

  36. Neonatal Emergency Transport Services play a fundamental role in neonatal care. Stabilization before transport of newborns suffering from severe respiratory failure is often a challenging problem and some crit...

    Authors: Gilda Belli, Ilaria Dovadola, Elettra Berti, Letizia Padrini, Elisabetta Agostini, Lisa Serafini, Anna Ingargiola, Gabriella Gabbrielli, Elena Sandini, Angelo Azzarà, Serena Catarzi, Maria Luce Cioni, Letizia Petrucci, Filomena Paternoster and Marco Moroni
    Citation: BMC Pediatrics 2022 22:335
    Content type: Research Published on:

  37. The commonly used dynamometers can be ineffective in evaluating handgrip in patients with Duchenne muscular dystrophy (DMD), especially children with generalized muscle weakness. The aim of this study was to a...

    Authors: Mariana Angélica de Souza, Edson Zangiacomi Martinez, Elisângela Aparecida da Silva Lizzi, Ananda Cezarani, Gabriela Barroso de Queiroz Davoli, Marjory Irineu Bená, Cláudia Ferreira da Rosa Sobreira and Ana Claudia Mattiello-Sverzut
    Citation: BMC Pediatrics 2022 22:334
    Content type: Research Published on:

  38. Childhood stunting and anemia are on the increase in many resource-constrained settings, without a counter increase in proper feeding practices such as exclusive breastfeeding. The objective of this study was ...

    Authors: Michael Ekholuenetale, Osaretin Christabel Okonji, Chimezie Igwegbe Nzoputam and Amadou Barrow
    Citation: BMC Pediatrics 2022 22:333
    Content type: Research Published on:

  40. This study aimed to investigate the prevalence of congenital heart disease (CHD) among school children in Qinghai province, a high-altitude region in China.

    Authors: Shangfei He, Fengqing Zhao, Xudong Liu, Fangzhou Liu, Yumei Xue, Hongtao Liao, Xianzhang Zhan, Weidong Lin, Murui Zheng, Junrong Jiang, Huoxing Li, Xiaofeng Ma, Shulin Wu and Hai Deng
    Citation: BMC Pediatrics 2022 22:331
    Content type: Research Published on:

  42. Aminoacyl-tRNA synthetases (ARSs) are enzymes responsible for attaching amino acids to tRNA, which enables protein synthesis. Mutations in isoleucyl-tRNA synthetase (IARS1) have recently been reported to be a gen...

    Authors: Ting-Ting Zou, Hua-Qin Sun, Yu Zhu, Tian-Tian He, Wen-Wu Ling, Hong-Mei Zhu, Zi-Yuan Lin, Yan-Yan Liu, Shan-Ling Liu, He Wang and Xue-Mei Zhang
    Citation: BMC Pediatrics 2022 22:329
    Content type: Case report Published on:

  43. Children are the focus of numerous health interventions throughout the world, yet the extent of children’s meaningful participation in research that informs the adaptation, implementation, and evaluation of he...

    Authors: Jean M. Hunleth, Julie S. Spray, Corey Meehan, Colleen Walsh Lang and Janet Njelesani
    Citation: BMC Pediatrics 2022 22:328
    Content type: Research article Published on:

  44. Despite the relative prevalence of small bowel and proximal colon perforation in the neonatal period, recto-sigmoid perforation is extremely rare. Full-term neonates experience intestinal perforation less freq...

    Authors: Zahra Jamali, Reza Sinaei, Elahe Raeisi Estabragh and Ahmad Ahangaran
    Citation: BMC Pediatrics 2022 22:327
    Content type: Case report Published on:

  45. The continued provision of safe food, free of aflatoxin remains a huge challenge in developing countries. Despite several favourable climatic conditions that facilitate aflatoxin contamination in Ethiopia, the...

    Authors: Mary Ayele, Demewoz Haile, Silvia Alonso, Heven Sime, Adugna Abera, Kifle Habte Balcha, Kedir Teji Roba, Geremew Tasew Guma and Bilal Shikur Endris
    Citation: BMC Pediatrics 2022 22:326
    Content type: Research Published on:

  46. Children with challenges integrating and processing sensory information can have difficulties participating in play and learning activities. One way to support participation is to offer sensory stimulation, su...

    Authors: Ann Natasja Nielsen, Karen la Cour and Åse Brandt
    Citation: BMC Pediatrics 2022 22:325
    Content type: Research article Published on:

  47. The prevalence of several cardiovascular metabolic disorders are increasingly cause for concern in adolescents worldwide. Given the complex interrelations between metabolic risk (MR) and sociodemographic varia...

    Authors: Sonimar de Souza, João Francisco de Castro Silveira, Kelin Cristina Marques, Anelise Reis Gaya, Silvia Isabel Rech Franke, Jane Dagmar Pollo Renner, James Philip Hobkirk, Sean Carroll and Cézane Priscila Reuter
    Citation: BMC Pediatrics 2022 22:324
    Content type: Research Published on:

  48. Gut microbiota plays an important role in the development of atopic dermatitis (AD). We aimed to elucidate research trends in gut microbiota and AD in children, to provide evidence and insights to the clinical...

    Authors: Yue Liu, Xiaofan Du, Shujie Zhai, Xiaodong Tang, Cuiling Liu and Weihong Li
    Citation: BMC Pediatrics 2022 22:323
    Content type: Research Published on:

  49. The rise in the indiscriminate use of antibiotics has become a major global public health problem and presents the biggest global health challenge in the twenty-first century. In developing countries, caregive...

    Authors: Richard Nyeko, Felix Otim, Evelyn Miriam Obiya and Catherine Abala
    Citation: BMC Pediatrics 2022 22:322
    Content type: Research Published on:

  50. Studies on cognition and brain networks after various forms of brain injury mainly involve traumatic brain injury, neurological disease, tumours, and mental disease. There are few related studies on surgical i...

    Authors: Xue-Yi Guan, Wen-Jian Zheng, Kai-Yu Fan, Xu Han, Xiang Li, Zi-Han Yan, Zheng Lu and Jian Gong
    Citation: BMC Pediatrics 2022 22:321
    Content type: Research Published on:
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BMC Pediatrics

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