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  1. Innate lymphoid cell (ILC) dysfunction is involved in numerous immune diseases, but this has not been demonstrated in Henoch-Schonlein purpura (HSP). This study aimed to investigate whether ILC dysfunction or ...

    Authors: Lili Zhang, Qiang Lin, Lijun Jiang, Mingfu Wu, Linlin Huang, Wei Quan and Xiaozhong Li
    Citation: BMC Pediatrics 2022 22:201
  2. The study was aimed to assess the prognostic power The Pediatric Risk of Mortality-3 (PRISM-3) and the Pediatric Index of Mortality-3 (PIM-3) to predict in-hospital mortality in a sample of patients admitted t...

    Authors: Zahra Rahmatinejad, Fatemeh Rahmatinejad, Majid Sezavar, Fariba Tohidinezhad, Ameen Abu-Hanna and Saeid Eslami
    Citation: BMC Pediatrics 2022 22:199
  3. Studies have shown that overweight and obesity conditions tend to be stable from childhood and adolescence to adulthood. Unfortunately, little is known about the evolution of abdominal obesity during childhood...

    Authors: Honorato Ortiz-Marrón, Maira Alejandra Ortiz-Pinto, Gloria Cabañas Pujadas, José Galo Martínez Mosquera, Marien Lorente Miñarro, Francisca Menchero Pinos, María Ordobás Gavín and Iñaki Galán
    Citation: BMC Pediatrics 2022 22:198
  4. Chorioamnionitis (CA) affects up to 3.9% of all deliveries worldwide and is one of the leading causes of early-onset neonatal sepsis. Fever≥380C is an essential criterion for the diagnosis of clinical CA. Obstetr...

    Authors: Anvar Paraparambil Vellamgot, Khalil Salameh, Lina Hussain M. Habboub, Rajesh Pattuvalappil, Naser Abulgasim Elkabir, Yousra Shehada Siam and Hakam Khatib
    Citation: BMC Pediatrics 2022 22:197
  5. The aims of this study were to analyze the relationships between minutes of play (MP) and maturity status, fitness, and hormonal levels and to explain how those measures influence the time of play.

    Authors: Ebrahim Eskandarifard, Hadi Nobari, Filipe Manuel Clemente, Rui Silva, Ana Filipa Silva and Antonio José Figueiredo
    Citation: BMC Pediatrics 2022 22:196
  6. Literature on factors influencing medication adherence within paediatric clinical trials is sparse. The Paracetamol and Ibuprofen in the Primary Prevention of Asthma in Tamariki (PIPPA Tamariki) trial is an op...

    Authors: Eunicia Tan, Karen Hoare, Judith Riley, Kathryn Fernando, Libby Haskell, Christopher JD McKinlay, Stuart R Dalziel and Irene Braithwaite
    Citation: BMC Pediatrics 2022 22:195
  7. Although cochlear implantation (CI) has been performed in Kazakhstan since 2007 little is known about quality of life of patients after CI. The aim of this study was to assess the health-related quality of life (...

    Authors: Ruslan Zhumabayev, Galiya Zhumabayeva, Gulnara Kapanova, Nailya Tulepbekova, Anuar Akhmetzhan and Andrej Grjibovski
    Citation: BMC Pediatrics 2022 22:194
  8. Immunization is among the most cost-effective health interventions to improve child survival. However, many countries in sub-Saharan Africa failed to achieve their national and international coverage targets r...

    Authors: Kalkidan Yibeltal, Sitota Tsegaye, Hasset Zelealem, Walelegn Worku, Meaza Demissie, Alemayehu Worku and Yemane Berhane
    Citation: BMC Pediatrics 2022 22:193
  9. In neonatal patients with necrotizing enterocolitis (NEC) the inflammatory response is mediated by a plurality of different proteins. The proteins olfactomedin 4 (OLFM4) and lysozyme (LYZ) are part of the inte...

    Authors: Sonja Diez, Marcus Renner, Veronika Bahlinger, Arndt Hartmann, Manuel Besendörfer and Hanna Müller
    Citation: BMC Pediatrics 2022 22:192
  10. The purpose of this project was to improve perinatal survival by introducing Moyo Fetal Heart Rate (FHR) Monitor coupled with neonatal resuscitation simulation training.

    Authors: Yuda Munyaw, Joshua Gidabayda, Anita Yeconia, Godfrey Guga, Esto Mduma and Paschal Mdoe
    Citation: BMC Pediatrics 2022 22:191
  11. Growth faltering is commonly encountered in breastfed infants during 4—6 months of age in low socioeconomic communities. The objective of this study was to describe the changes of growth indices with age, timi...

    Authors: K. Sithamparapillai, D. Samaranayake and V. P. Wickramasinghe
    Citation: BMC Pediatrics 2022 22:190
  12. Acute respiratory infections (ARI) are the leading cause of morbidity and mortality in children below 5 years of age.

    Authors: Aparna Mukherjee, K. R. Jat, Rakesh Lodha, Jagdish Prasad Goyal, Javeed Iqbal Bhatt, Rashmi Ranjan Das, Vinod Ratageri, Bhadresh Vyas and S. K. Kabra
    Citation: BMC Pediatrics 2022 22:189
  13. Febrile infants ≤ 90 days old make up a significant proportion of patients seeking care in the emergency department (ED). These infants are vulnerable to serious bacterial infections (SBIs) and early identific...

    Authors: Tan Shi Rui Victoria, Ong Gene Yong-Kwang, Lee Khai Pin, Ganapathy Sashikumar and Chong Shu-Ling
    Citation: BMC Pediatrics 2022 22:188
  14. The inconsistent use of antiretroviral therapy can lead to the risk of cross-resistance between drugs. This reduces subsequent antiretroviral drug options. The burden of initial antiretroviral therapy ranges f...

    Authors: Molla Azmeraw, Yinager Workineh, Friehiwot Girma, Amare Kassaw, Gashaw Kerebeh, Abraham Tsedalu, Agimasie Tigabu, Teshale Mengesha, Eleni Dagnaw, Dessie Temesgen, Biruk Beletew, Getenet Dessie and Melsew Dagne
    Citation: BMC Pediatrics 2022 22:186
  15. There is limited data on pediatric ventilator-associated events (PedVAE) in the neonatal intensive care unit (NICU) setting, since the CDC mandated state reporting of these events in January 2019. This study s...

    Authors: Novisi Arthur, Ishminder Kaur and Alison J. Carey
    Citation: BMC Pediatrics 2022 22:185
  16. In North Denmark Region (NDR), the incidence of Eosinophilic Oesophagitis (EoE) among adults has increased following a new biopsy protocol in 2011, whereas data on the incidence of EoE among children is lacking.

    Authors: Martin Hollænder, Jacob Holmen Terkelsen, Frederik Kramme, Kasper Bredal, Kristian Kragholm, Kasper Dalby, Søren Hagstrøm, Dorte Melgaard and Anne Lund Krarup
    Citation: BMC Pediatrics 2022 22:183
  17. Central nervous system (CNS) infection has been an ongoing concern in paediatrics. The FilmArray® Meningoencephalitis (FAME) panel has greater sensitivity in identifying the aetiology of CNS infections. This s...

    Authors: Mirta Acuña, Dona Benadof, Karla Yohannessen, Yennybeth Leiva and Pascal Clement
    Citation: BMC Pediatrics 2022 22:182
  18. X-linked agammaglobulinemia (XLA) is an Inborn Errors of Immunity (IEI) characterized by pan-hypogammaglobulinemia and low numbers of B lymphocytes due to mutations in BTK gene. Usually, XLA patients are not susc...

    Authors: Ronaldo da Silva Francisco Junior, Guilherme Loss de Morais, Joseane Biso de Carvalho, Cristina dos Santos Ferreira, Alexandra Lehmkuhl Gerber, Ana Paula de C Guimarães, Flávia Anisio Amendola, Fernanda Pinto-Mariz, Zilton Farias Meira de Vasconcelos, Ekaterini Simões Goudouris and Ana Tereza Ribeiro de Vasconcelos
    Citation: BMC Pediatrics 2022 22:181
  19. Bloodstream infections (BSIs) cause significant morbidity and mortality in critically ill children but treatment duration is understudied. We describe the durations of antimicrobial treatment that critically i...

    Authors: Sandra Pong, Robert A. Fowler, Srinivas Murthy, Jeffrey M. Pernica, Elaine Gilfoyle, Patricia Fontela, Asgar H. Rishu, Nicholas Mitsakakis, James S. Hutchison, Michelle Science, Winnie Seto, Philippe Jouvet and Nick Daneman
    Citation: BMC Pediatrics 2022 22:179
  20. Mental health in adolescence is an increasing global public health concern. Over half of all mental disorders debut by 14 years of age and remain largely untreated up to adulthood, underlining the significance...

    Authors: Kristina Carlén, Sakari Suominen, Lilly Augustine, Maiju M. Saarinen, Minna Aromaa, Päivi Rautava, André Sourander and Matti Sillanpää
    Citation: BMC Pediatrics 2022 22:177
  21. Invasive bacterial infections (IBI) in children present a difficult clinical challenge. They are often life-threatening, however in the early stages they can be hard to differentiate from benign viral infectio...

    Authors: Michael Paul Corr, Derek Fairley, James P. McKenna, Michael D. Shields and Thomas Waterfield
    Citation: BMC Pediatrics 2022 22:176
  22. Although many studies have described an increased risk of necrotizing enterocolitis in duct dependent congenital heart diseases, very few have investigated its occurrence in full-term infants with duct depende...

    Authors: Gwang-Jun Choi, Jinyoung Song, Hanna Kim, June Huh, I-Seok Kang, Yun Sil Chang, Se In Sung and Myung Chul Hyun
    Citation: BMC Pediatrics 2022 22:174
  23. There is significant variability in clinical pathways available in the diagnostic assessment of ASD, including the order and timing of allied health assessments in relation to paediatrician consultations. Alli...

    Authors: Thuy T. Frakking, John Waugh, Christopher Carty, Alison Burmeister, Annabelle Marozza, Sue Hobbins, Michelle Kilah, Michael David, Lisa Kane, Susan McCormick and Hannah E. Carter
    Citation: BMC Pediatrics 2022 22:173
  24. Understanding of the role of children in COVID-19 transmission has significant implications for school and childcare policies, as well as appropriate targeting of vaccine campaigns. The objective of this syste...

    Authors: Sarah L Silverberg, Bei Yuan Zhang, Shu Nan Jessica Li, Conrad Burgert, Hennady P Shulha, Vanessa Kitchin, Laura Sauvé and Manish Sadarangani
    Citation: BMC Pediatrics 2022 22:172
  25. Early puberty increases risk of adverse health conditions throughout the life course. US girls are experiencing earlier puberty without clear reasons. Studies suggest early life factors, such as infant growth,...

    Authors: Sara Aghaee, Charles P. Quesenberry Jr, Julianna Deardorff, Lawrence H. Kushi, Louise C. Greenspan, Assiamira Ferrara and Ai Kubo
    Citation: BMC Pediatrics 2022 22:171
  26. Data on childhood disability is essential for planning health, education and other services. However, information is lacking in many low- and middle-income countries, including Niger. This study uses the Key I...

    Authors: Lena Morgon Banks, Jing Liu, Anne Kielland, Ali Bako Tahirou, Abdoul Karim Seydou Harouna, Islay Mactaggart, Ragnhild Dybdahl, Dan Firoun Mounkaila and Arne Grønningsæter
    Citation: BMC Pediatrics 2022 22:170
  27. Pneumonia is the leading cause of mortality in pediatric population. The etiology of pneumonia in this population is variable and changes according to age and disease severity and where the study is conducted....

    Authors: Zulma Vanessa Rueda, Yudy Aguilar, María Angélica Maya, Lucelly López, Andrea Restrepo, Carlos Garcés, Olga Morales, Claudia Roya-Pabón, Mónica Trujillo, Catalina Arango, Ángela Rocio Copete, Cristian Vera, Margarita Rosa Giraldo, Mariana Herrera and Lázaro A. Vélez
    Citation: BMC Pediatrics 2022 22:169
  28. Tenofovir disoproxil fumarate (TDF) is effectively used as the first-line antiviral for chronic hepatitis B virus (HBV) infection in adults and children older than 12 years. To date, no confirmed case of virol...

    Authors: Chien-Yu Chen, Christina Hajinicolaou, Priya Walabh, Luicer Anne Olubayo Ingasia, Ernest Song and Anna Kramvis
    Citation: BMC Pediatrics 2022 22:168
  29. This study aims to explore and elucidate parents’ experience of newborn screening [NBS], with the overarching goal of identifying desiderata for the development of informatics-based educational and health mana...

    Authors: Mike Conway, Truc Thuy Vuong, Kim Hart, Andreas Rohrwasser and Karen Eilbeck
    Citation: BMC Pediatrics 2022 22:167
  30. Respiratory virus infection is common in early childhood, and children may be symptomatic or symptom-free. Little is known regarding the association between symptomatic/asymptomatic infection and particular cl...

    Authors: Elizabeth Powell, Edward Sumner, Alex G. Shaw, Ronan Calvez, Colin G. Fink and J. Simon Kroll
    Citation: BMC Pediatrics 2022 22:166
  31. Birth asphyxia is the major public health problem in the world. It is estimated that around 23% of all newborn deaths are caused by birth asphyxia worldwide. Birth asphyxia is the top three causes of newborn d...

    Authors: Sisay Shine Tegegnework, Yeshfanos Tekola Gebre, Sindew Mahmud Ahmed and Abrham Shitaw Tewachew
    Citation: BMC Pediatrics 2022 22:165
  32. Immune thrombocytopenia (ITP) is the most common etiology of acquired thrombocytopenia diseases in children. ITP is characterized by the immune-mediated decreased formation and excessive destruction of platele...

    Authors: Qi Wang, Jia Wei, Xi Jia, Xiao Feng, Zhenghua Ji, Xueqiang Ji and Xuejun Shao
    Citation: BMC Pediatrics 2022 22:164
  33. Colic and sleep problems are common among infants, constitute challenges and distress for parents, and are often reasons for seeking help from health professionals. The literature debates whether infant colic ...

    Authors: Sølvi Helseth, Nina Misvær, Milada Småstuen, Randi Andenæs and Lisbeth Valla
    Citation: BMC Pediatrics 2022 22:163
  34. To explore and analyze the causes and related influencing factors of pediatric fractures, and provide theoretical basis for reducing the incidence and adverse effects of pediatric fractures.

    Authors: Xin Qiu, Hansheng Deng, Qiru Su, Shuaidan Zeng, Shuai Han, Shicheng Li, Zhiwen Cui, Tianfeng Zhu, Gen Tang, Zhu Xiong and Shengping Tang
    Citation: BMC Pediatrics 2022 22:161
  35. This study aimed to assess the quality of global guidelines or consensus statements for newborn and childhood hearing screening, as well as to compare various guidelines between other countries and China.

    Authors: Cheng Wen, Xuelei Zhao, Yue Li, Yiding Yu, Xiaohua Cheng, Xiaohong Li, Kui Deng, Xuelian Yuan and Lihui Huang
    Citation: BMC Pediatrics 2022 22:160
  36. Early support for children with developmental disabilities is crucial but frequently unavailable in low-resource settings. We conducted a mixed-methods evaluation to assess the feasibility, acceptability, and ...

    Authors: S. Sadoo, R. Nalugya, R. Lassman, M. Kohli-Lynch, G. Chariot, H. G. Davies, E. Katuutu, M. Clee, J. Seeley, E. L. Webb, R. Mutoni Vedastine, F. Beckerlegge and C. J. Tann
    Citation: BMC Pediatrics 2022 22:158
  37. Outpatient therapeutic program (OTP) brings the services for the management of Severe Acute Malnutrition (SAM) closer to the community by making services available at decentralized treatment points within the ...

    Authors: Smegnew Gichew Wondie, Beakal Zinab, Getu Gizaw and Meseret Tamrat
    Citation: BMC Pediatrics 2022 22:157
  38. The amplitude-integrated EEG (aEEG) is a widely used monitoring tool in neonatology / pediatric intensive care. It takes into account the amplitudes, but not the frequency composition, of the EEG. Advantages o...

    Authors: Barbara Schultz, Michael Schultz, Martin Boehne and Nils Dennhardt
    Citation: BMC Pediatrics 2022 22:156
  39. The Supplemental Nutrition Assistance Program (SNAP) has well-established positive impacts on child health outcomes, including increased birth weight and decreased likelihood of underweight status. Studies in ...

    Authors: Stephen Rogers, Arvin Garg, Yorghos Tripodis, Annelise Brochier, Emily Messmer, Mikayla Gordon Wexler and Alon Peltz
    Citation: BMC Pediatrics 2022 22:155
  40. Infectious diseases like the common cold, otitis media, or gastroenteritis frequently occur in childhood. In addition to prescription drugs, parents often use supplementary over-the-counter (OTC) products reco...

    Authors: Matthias Gerlitz, Peter Voitl, Julian J. M. Voitl and Susanne C. Diesner-Treiber
    Citation: BMC Pediatrics 2022 22:154
  41. Preterm related complications are the single largest direct cause of neonatal deaths throughout the world, responsible for 35% of the world’s neonatal death (1.1 million deaths/year). In Ethiopia preterm relat...

    Authors: Dires Birhanu, Bereket Gebremichael, Tewodros Tesfaye, Misrak Tadesse, Fekadeselassie Belege, Yohannes Godie, Markos Wodaje and Eyerusalem Tamiru
    Citation: BMC Pediatrics 2022 22:153
  42. Guillain-Barré syndrome is the most common cause of flaccid paralysis, with multiple known clinical variants. Autonomic dysfunction, although frequently reported in the clinical course, is often overlooked in ...

    Authors: C. Bonilla, M. I. Alvarez-Olmos, C. Uribe and J. Fernández-Sarmiento
    Citation: BMC Pediatrics 2022 22:152
  43. The “Assessment of Motor Repertoire—3 to 5 Months”, which is a part of Prechtl's General Movements Assessment (GMA), has been gradually applied to infants with genetic metabolic disorders. However, there have ...

    Authors: Jun Wang, Xiushu Shen, Hong Yang, Wei Shi, Xiaoyun Zhu, Herong Gao, Huanhuan Yin, Fanzhe Meng and Yun Wu
    Citation: BMC Pediatrics 2022 22:150

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