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  1. Neonatal sepsis, a perilous medical situation, is typified by the malfunction of organs and serves as the primary reason for neonatal mortality. Nevertheless, the mechanisms underlying newborn sepsis remain am...

    Authors: Yun Hang, Huanxia Qu, Juanzhi Yang, Zhang Li, Shiqi Ma, Chenlu Tang, Chuyan Wu, Yunlei Bao, Feng Jiang and Jin Shu
    Citation: BMC Pediatrics 2024 24:67
  2. Human milk fortifier (HMF) composition has been optimized recently. But clinical evidence of its safety and efficacy is limited in Chinese population. The aim of this study was to evaluate effects of a new HMF...

    Authors: Junyan Han, Lan Zhang, Rong Zhang, Shuping Han, Jianxing Zhu, Xuefeng Hu, Jianhua Sun, Gang Qiu, Zhenghong Li, Weili Yan, Lijuan Xie, Xiuxia Ye, Xiaohui Gong, Liling Li, Fei Bei, Chan Liu…
    Citation: BMC Pediatrics 2024 24:61
  3. NUDT2 is an enzyme important for maintaining the intracellular level of the diadenosine tetraphosphate (Ap4A). Bi-allelic loss of function variants in NUDT2 has recently been reported as a rare cause of intellect...

    Authors: Bo Bi, Xiaohong Chen, Shan Huang, Min Peng, Weiyue Gu, Hongmin Zhu and Yangcan Ming
    Citation: BMC Pediatrics 2024 24:60
  4. The aim of this paper is to review the topic of neonatal fractures of the upper limb, describing the different types of fractures focusing on the etiology, epidemiology, risk factors, clinical approach, diagno...

    Authors: Marcos Carvalho, Maria Inês Barreto, João Cabral, Inês Balacó and Cristina Alves
    Citation: BMC Pediatrics 2024 24:59
  5. Intakes of fiber, iron, zinc, calcium, vitamin D, vitamin A, and folate were shown to be low in a substantial proportion of infants and children in Lebanon. The study aims to identify the top food sources of f...

    Authors: Fatima Al Zahraa Chokor, Nahla Hwalla, Farah Naja and Lara Nasreddine
    Citation: BMC Pediatrics 2024 24:57
  6. Moderate acute malnutrition (MAM) affects over 30 million children aged < 5 years worldwide. MAM may confer a greater risk of developing severe malnutrition and even mortality in children. Assessing risk facto...

    Authors: Rodrick Kisenge, Usha Dhingra, Chris A. Rees, Enju Liu, Arup Dutta, Deb Saikat, Pratibha Dhingra, Sarah Somji, Chris Sudfeld, Jon Simon, Per Ashorn, Sunil Sazawal, Christopher P. Duggan and Karim Manji
    Citation: BMC Pediatrics 2024 24:56
  7. Walking ability, which has been connected to better health and independence, is one of the daily activities that is negatively impacted by Down syndrome. Thus, the objective of this study was to examine the wa...

    Authors: Saad A. Alhammad, Amani S. Alqahtani, Khalid S. Alwadeai, Maha F. Algabbani and Adel A. Alhusaini
    Citation: BMC Pediatrics 2024 24:55
  8. The increasing prevalence of metabolic syndrome, type 2 diabetes, and insulin resistance are driven by complex interactions between genetic and environmental factors. One of the single nucleotide polymorphisms...

    Authors: Ahmad Gholami, Nima Montazeri-Najafabady, Iman Karimzadeh, Mohammad Hossein Dabbaghmanesh and Elnaz Talei
    Citation: BMC Pediatrics 2024 24:54
  9. During childhood and adolescence, skeletal microarchitecture and bone mineral density (BMD) undergo significant changes. Peak bone mass is built and its level significantly affects the condition of bones in la...

    Authors: Anna Kopiczko, Michał Czapla, Raúl Juárez-Vela, Catherine Ross and Bartosz Uchmanowicz
    Citation: BMC Pediatrics 2024 24:53
  10. The study aimed to explore the effectiveness of bedside lung ultrasound (LUS) combined with the PaO2/FiO2 (P/F) ratio in evaluating the outcomes of high-flow nasal cannula (HFNC) therapy in infants with severe pn...

    Authors: Li-Ling Zheng, Rou Chen, Chan-Hua Zheng, Xiao-Juan Dai, Wei-Da Zheng and Jia-Xiang Zhang
    Citation: BMC Pediatrics 2024 24:51
  11. Late-onset neonatal sepsis (LOS) is common in preterm neonates, with increasing incidence in recent years. In the present study, we examined the epidemiology, clinical presentation, and complications of LOS in...

    Authors: Paraskevi Stylianou-Riga, Theodora Boutsikou, Panayiotis Kouis, Kyriaki Michailidou, Paraskevi Kinni, Rozeta Sokou, Zoi Iliodromiti, Constantinos Pitsios, Panayiotis K. Yiallouros and Nicoletta Iacovidou
    Citation: BMC Pediatrics 2024 24:50
  12. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) infection has many neurological manifestations, and its effects on the nervous system are increasingly recognized. There has been no systematic analy...

    Authors: Yue Yang, Tao Yu, Jie Yang, Jia Luo, Xuan Liu, Chong Mu, Xiaochuan Wang, Yao Deng and Rong Luo
    Citation: BMC Pediatrics 2024 24:49
  13. It is still controversial for neonates or children to choose normal saline or heparin solution in the care of peripheral intravenous catheters. This meta-analysis aimed to evaluate the effects of heparin versu...

    Authors: Ran Li, Qiaoqi Zheng, Nengyue Chen and Li Zhao
    Citation: BMC Pediatrics 2024 24:48
  14. We aimed to elucidate the underlying disease in a Hungarian family, with only one affected family member, a 16-year-old male Hungarian patient, who developed global developmental delay, cognitive impairment, b...

    Authors: Nikoletta Nagy, Margit Pál, Dóra Nagy, Barbara Anna Bokor, Aliz Zimmermann, Balázs Gellén, András Salamon, László Sztriha, Péter Klivényi and Márta Széll
    Citation: BMC Pediatrics 2024 24:47
  15. Therapeutic hypothermia for infants with moderate to severe hypoxic-ischemic encephalopathy is well established as standard of care in high-income countries. Trials from low- and middle-income countries have s...

    Authors: Karen Haugvik Francke, Ragnhild Støen, Niranjan Thomas and Karoline Aker
    Citation: BMC Pediatrics 2024 24:46
  16. High mobility group box-1 (HMGB1) is an endogenous danger signal that mediates activation of the innate immune response including NLR pyrin domain containing 3 (NLRP3) inflammasome activation and proinflammato...

    Authors: Xing-Guang Ye, Feng-Zhi She, Dong-Ni Yu, Li-Qian Wu, Yan Tang, Ben-Ze Wu, Shi-Wei Dong, Jie-Min Dai, Xing Zhou and Zhi-Gang Liu
    Citation: BMC Pediatrics 2024 24:44
  17. Peak expiratory flow rate (PEFR) is an important tool for assessing lung function, which can be affected by environmental and physical factors such as altitude, nutrition, genetics, age, height, and weight. Co...

    Authors: Willbroad Kyejo, Nancy Matillya, Neelam Ismail, Gloria Gachocha, Hajaj Salum, Rosebella Iseme and Mariam Noorani
    Citation: BMC Pediatrics 2024 24:42
  18. While triple anti-retroviral therapy (ART) has improved HIV-infected children surviving into adolescence and adulthood, these children remain vulnerable to HIV-related psychological disturbance due to both the...

    Authors: Paul Uchizi Kaseka, Maggie Zgambo, Balwani Chingatichifwe Mbakaya, Mathews Lazarus, Obed Nkhata and Fatch W. Kalembo
    Citation: BMC Pediatrics 2024 24:41
  19. Unhealthy food consumption that begins early in life is associated with a higher risk of nutrient inadequacy and related chronic diseases later in life. Healthy eating and consumption of important nutrients he...

    Authors: Enyew Getaneh Mekonen, Alebachew Ferede Zegeye, Belayneh Shetie Workneh, Masresha Asmare Techane, Tadesse Tarik Tamir and Bewuketu Terefe
    Citation: BMC Pediatrics 2024 24:40
  20. Clonidine stimulation test has been widely used in the diagnosis of growth hormone deficiency in children with short stature with a high level of reliability. However, it may cause hypotension, which usually a...

    Authors: Wentao Yang, Shanshan Wang, Wei Gu, Francis Manyori Bigambo, Yubing Wang and Xu Wang
    Citation: BMC Pediatrics 2024 24:39
  21. Acute respiratory infection (ARI) is one of the leading causes of morbidity and mortality among children under five globally, particularly in regions like South Asia and sub-Saharan Africa. Bangladesh has made...

    Authors: Moktarul Islam, Kariul Islam, Koustuv Dalal and Mohammad Delwer Hossain Hawlader
    Citation: BMC Pediatrics 2024 24:38
  22. Generating rigorous evidence to inform care for rare diseases requires reliable, sustainable, and longitudinal measurement of priority outcomes. Having developed a core outcome set for pediatric medium-chain a...

    Authors: Ryan Iverson, Monica Taljaard, Michael T. Geraghty, Michael Pugliese, Kylie Tingley, Doug Coyle, Jonathan B. Kronick, Kumanan Wilson, Valerie Austin, Catherine Brunel-Guitton, Daniela Buhas, Nancy J. Butcher, Alicia K. J. Chan, Sarah Dyack, Sharan Goobie, Cheryl R. Greenberg…
    Citation: BMC Pediatrics 2024 24:37
  23. To understand community perspectives on the effects of high ambient temperature on the health and wellbeing of neonates, and impacts on post-partum women and infant care in Kilifi.

    Authors: Adelaide Lusambili, Sari Kovats, Britt Nakstad, Veronique Filippi, Peter Khaemba, Nathalie Roos, Cherie Part, Stanley Luchters, Matthew Chersich, Jeremy Hess, Kadidiatou Kadio and Fiona Scorgie
    Citation: BMC Pediatrics 2024 24:36
  24. Premature neonates need adequate nutritional support to provide sufficient essential nutrients for optimal growth. Calcium (Ca) is one of the important nutrients in parental nutrition support of premature infa...

    Authors: Siamak Shiva, Khatereh Rezazadeh, Asmar Amiraslanzadeh, Bahareh Mehramuz, Sadollah Yeganehdoost and Majid Mahallei
    Citation: BMC Pediatrics 2024 24:35
  25. Familial hemophagocytic lymphohistiocytosis (FHL) is an immunological disorder characterized by overactivation of macrophages and T lymphocytes. This autosomal recessive condition has been characterized into m...

    Authors: Chinmayee B. Nagaraj, Diana S. Brightman, Hannah Rea, Emily Wakefield, Nina V. G. Harkavy, Lisa Dyer and Wenying Zhang
    Citation: BMC Pediatrics 2024 24:34
  26. Family Based Behavioral Treatments (FBBT) are reported to have a favorable impact on the short and mid-term evolution on the body mass index (BMI) of adolescents suffering from obesity. This study investigated...

    Authors: Catherine Chamay Weber, Claudine Gal-Duding and Albane BR Maggio
    Citation: BMC Pediatrics 2024 24:33
  27. Recombinant human growth hormone (rhGH) therapy is beneficial for children with Prader–Willi syndrome (PWS) in improving short stature and metabolism, but the effect of early rhGH treatment on respiratory and ...

    Authors: Haiyan Guo, Jinrong Fu, Yufeng Zhou, Feihong Luo and Ruoqian Cheng
    Citation: BMC Pediatrics 2024 24:32
  28. Following rubella virus control, the most important cause of congenital infections is human cytomegalovirus (HCMV). Congenital CMV (cCMV) may happen both in primary and non-primary maternal infections. The pre...

    Authors: Negar Mirsalehi, Jila Yavarian, Nastaran Ghavami, Maryam Naseri, Farshad Khodakhah, Somayeh Shatizadeh Malekshahi, Sevrin Zadheidar, Talat Mokhtari-Azad and Nazanin-Zahra Shafiei-Jandaghi
    Citation: BMC Pediatrics 2024 24:31
  29. Traditional feeding practices are widespread in Indonesia. Therefore, using traditional feeding practices commonly used among mothers, this study examined the association between these practices and stunting a...

    Authors: Yuly Astuti, Seung Chun Paek, Natthani Meemon and Thammarat Marohabutr
    Citation: BMC Pediatrics 2024 24:29
  30. Pediatric myelodysplastic syndromes (MDS) are rare disorders with an unrevealed pathogenesis. Our aim is to explore the role of genetic factors in the pathogenesis of MDS in children with different outcomes an...

    Authors: Ying Li, Li Cheng, Yun Peng, Lin Wang, Wenzhi Zhang, Yuhong Yin, Jing Zhang and Xiaoyan Wu
    Citation: BMC Pediatrics 2024 24:28
  31. The purpose of the project was to assess the health seeking behaviour and knowledge on neonatal danger signs among neonatal caregivers in Upper Denkyira East Municipality.

    Authors: Philip Gyaase, Edward Aduse-Poku, Mavis Opoku Lanquaye, Emmanuel Boateng Acheampong and David Ben Sampson
    Citation: BMC Pediatrics 2024 24:27
  32. Bisphenol A diglycidyl ether (BADGE) and Bisphenol F diglycidyl ether (BFDGE) are used in medical devices, such as intravenous sets, syringes, and catheters. Several studies have reported that these compounds ...

    Authors: Mami Kuwamura, Kentaro Tanaka, Atsuto Onoda, Kentaro Taki, Chihaya Koriyama, Kyoko Kitagawa, Toshihiro Kawamoto and Mayumi Tsuji
    Citation: BMC Pediatrics 2024 24:26
  33. Nutrition plays a crucial role for the bio-psycho-social growth and development of children. Mother-child pairs’ eating-feeding problems can be hypothesized to relate to the child’s nutritional status and livi...

    Authors: Gülsüm Özen, Bülent Güneş, Suzan Yalçın and Sıddika Songül Yalçın
    Citation: BMC Pediatrics 2024 24:25
  34. A low incidence of eosinophilic esophagitis (EoE) in children in the North Denmark Region (NDR) were measured in 2007–2017. Few of the children diagnosed before 2017 were treated to remission suggesting a lack...

    Authors: Kasper Bredal, Line Tegtmeier Frandsen, Jacob Holmen Terkelsen, Martin Hollænder Nielsen, Dorte Melgaard and Anne Lund Krarup
    Citation: BMC Pediatrics 2024 24:24
  35. Diarrhea is the second leading cause of morbidity and mortality for under-five children which cause about 525,000 deaths annually. Even though diarrheal diseases have decreased substantially at the global leve...

    Authors: Belayneh Shetie Workneh, Enyew Getaneh Mekonen and Alebachew Ferede Zegeye
    Citation: BMC Pediatrics 2024 24:23
  36. The Enhanced Recovery After Cardiac Surgery (ERACS) programs are comprehensive multidisciplinary interventions to improve patients’ recovery. The application of the ERAS principle in pediatric patients has not...

    Authors: Dou Dou, Yuan Jia, Su Yuan, Yang Wang, Yinan Li, Hongbai Wang, Jie Ding, Xie Wu, Dongyun Bie, Qiao Liu, Ran An, Haoqi Yan and Fuxia Yan
    Citation: BMC Pediatrics 2024 24:22
  37. Allergic rhinitis is the most common allergic disease. It can accompany psychological disorders such as tic disorders due to the prolonged course of the symptoms of allergic rhinitis. This pioneer case-control...

    Authors: Hossein Esmaeilzadeh, Mohammad Reza Yousefi, Negar Mortazavi, Mohammad Amin Gholami, Mohebat Vali and Seyed Ali Dastgheib
    Citation: BMC Pediatrics 2024 24:20
  38. The experience of benefit-finding and growth (BFG), defined as perceiving positive life changes resulting from adversity, is increasingly studied among youths with chronic health conditions (CCs). However, emp...

    Authors: Roman E. von Rezori, Harald Baumeister, Reinhard W. Holl, Kirsten Minden, Annabel S. Müller-Stierlin, Christina Reinauer, Svenja Temming and Petra Warschburger
    Citation: BMC Pediatrics 2024 24:19
  39. Many neurodevelopmental abnormalities are connected to autism spectrum disorder (ASD), which can result in inflammation and elevated cytokine levels due to immune system dysregulation. Interleukin (IL)-17 A an...

    Authors: Dina E. Sallam, Youstina S. Shaker, Gehan A. Mostafa, Reham M. El-Hossiny, Sara I. Taha and Mostafa Abd Elazeem Hassan Ahamed
    Citation: BMC Pediatrics 2024 24:18
  40. Hypertensive disorders in pregnancy can cause prenatal placental perfusion with insufficient blood supply to the fetus, resulting in fetal exposure to hypoxia and leading to disturbance of neonatal hematopoiet...

    Authors: Zewudu Mulatie, Melak Aynalem and Solomon Getawa
    Citation: BMC Pediatrics 2024 24:17
  41. The COVID-19 pandemic has globally impacted health service access, delivery and resources. There are limited data regarding the impact on the prevention of mother to child transmission (PMTCT) service delivery...

    Authors: Hannah Gannon, Elizabeth Chappell, Deborah Ford, Diana M Gibb, Anesu Chimwaza, Ngoni Manika, Catherine J Wedderburn, Zivai Mupambireyi Nenguke, Frances M Cowan, Tom Gibb, Andrew Phillips, Angela Mushavi, Felicity Fitzgerald, Michelle Heys, Simbarashe Chimhuya and Mutsa Bwakura-Dangarembizi
    Citation: BMC Pediatrics 2024 24:16
  42. This study aimed to (1) characterise sleep disturbances and emotional/behavioural difficulties among healthy German children and adolescents aged 3 to 13 years, (2) examine the association between parent-repor...

    Authors: Theresa Fulfs, Tanja Poulain, Mandy Vogel, Kolja Nenoff and Wieland Kiess
    Citation: BMC Pediatrics 2024 24:15

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