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  1. Early warning scores for neonatal mortality have not been designed for low income countries. We developed and validated a score to predict mortality upon admission to a NICU in Ethiopia.

    Authors: Rishi P. Mediratta, Ashenafi Tazebew Amare, Rasika Behl, Bradley Efron, Balasubramanian Narasimhan, Alemayehu Teklu, Abdulkadir Shehibo, Mulugeta Ayalew and Saraswati Kache

    Citation: BMC Pediatrics 2020 20:238

    Content type: Research article

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  2. Diarrheal diseases are the second major cause of death among under-five children globally. It kills about 2.5 million people each year, with 60–70% of them being children under 5 years of age. It is also the s...

    Authors: Adugna Fenta, Kassahun Alemu and Dessie Abebaw Angaw

    Citation: BMC Pediatrics 2020 20:236

    Content type: Research article

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  3. Donor human milk (DHM) has been recommended for premature infants if mothers’ own milk is not available. The aim of this study was to increase the knowledge about the utilization rate and handling of DHM among...

    Authors: Daniel Klotz, Stefanie Jansen, René Glanzmann, Nadja Haiden, Hans Fuchs and Corinna Gebauer

    Citation: BMC Pediatrics 2020 20:235

    Content type: Research article

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  4. Respiratory distress syndrome (RDS) is a frequent complication of premature birth. Treating RDS by continuous positive airway pressure and less invasive surfactant administration (LISA) may reduce bronchopulmo...

    Authors: Christian A. Maiwald, Julia Dick, Matthias Marschal, Christian Gille, Axel R. Franz and Christian F. Poets

    Citation: BMC Pediatrics 2020 20:234

    Content type: Research article

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  5. Though effective treatment programs for severely malnourished children are available, mortality rate among children with acute malnutrition continue to rise and little is known about its long-term outcomes and...

    Authors: Eman Ramadan Ghazawy, Gihan Mohammed Bebars and Ehab Salah Eshak

    Citation: BMC Pediatrics 2020 20:233

    Content type: Research article

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  6. Stunting is a major public health issue in most of developing countries. Although, its worldwide prevalence is decreasing slowly but the number of stunted children is still rising in Pakistan. Stunting is high...

    Authors: Mahvish Ponum, Saadia Khan, Osman Hasan, Muhammad Tahir Mahmood, Asad Abbas, Mehwish Iftikhar and Reema Arshad

    Citation: BMC Pediatrics 2020 20:232

    Content type: Research article

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  7. Road Traffic Injuries (RTIs) are a leading cause of disabilities and mortalities in Iran. The occurrence of RTIs among children is increasing. This study aims are to assess RTIs among Iranian children and to d...

    Authors: Hesam Ghiasvand, Payam Roshanfekr, Delaram Ali, Hossein Malekafzali Ardakani, Amanda N. Stephens and Bahram Armoon

    Citation: BMC Pediatrics 2020 20:231

    Content type: Research article

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  8. The objective of this prospective, multidisciplinary and multicenter study was to explore the effect of a cleft lip, associated or not with a cleft palate, on parents, on parent-infant relationship, and on the...

    Authors: Bruno Grollemund, Caroline Dissaux, Pascale Gavelle, Carla Pérez Martínez, Jimmy Mullaert, Toni Alfaiate and Antoine Guedeney

    Citation: BMC Pediatrics 2020 20:230

    Content type: Research article

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  9. Sleep is especially important for infants, since it stimulates the development of neural connections in their brains. Psychological stress such as anxiety could affect sleep quality. This study investigated th...

    Authors: Maryam Montazeri, Mojgan Mirghafourvand, Khalil Esmaeilpour, Sakineh Mohammad-Alizadeh-Charandabi and Paria Amiri

    Citation: BMC Pediatrics 2020 20:229

    Content type: Research article

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  10. Although hyperglycemia and pancreatitis are known side effects of L-asparaginase, both contributing to the development of diabetic ketoacidosis (DKA) is unfamiliar in literature.

    Authors: Patel Zeeshan Jameel, Sham Lohiya, Amol Dongre, Sachin Damke and Bhavana B. Lakhkar

    Citation: BMC Pediatrics 2020 20:228

    Content type: Case report

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  11. Recently, the World Health Organization has declared the coronavirus disease 2019 (COVID-19) outbreak a public health emergency of international concern. So far, however, limited data are available for childre...

    Authors: Yang Li, Jianghui Cao, Xiaolong Zhang, Guangzhi Liu, Xiaxia Wu and Baolin Wu

    Citation: BMC Pediatrics 2020 20:227

    Content type: Research article

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  12. A central aim for pediatric nutrition is to develop infant formula compositionally closer to human milk. Milk fat globule membranes (MFGM) have shown to have functional components that are found in human milk,...

    Authors: Rosario Toro-Campos, Cecilia Algarín, Patricio Peirano, Marcela Peña, Teresa Murguia-Peniche, Steven S. Wu and Ricardo Uauy

    Citation: BMC Pediatrics 2020 20:225

    Content type: Study protocol

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  13. Rapid weight gain (RWG) in infants is associated with overweight and obesity in childhood and beyond, highlighting the need for early intervention.

    Authors: Elizabeth Denney-Wilson, Kaniz Fatema, Emma Elcombe, Suzanne Ingram, Mark Harris and Elizabeth Comino

    Citation: BMC Pediatrics 2020 20:224

    Content type: Research article

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  14. Exome and genome sequencing are routinely used in clinical care and research. These technologies allow for the detection of pathogenic/likely pathogenic variants in clinically actionable genes. However, fueled...

    Authors: Juliann M. Savatt, Jennifer K. Wagner, Steven Joffe, Alanna Kulchak Rahm, Marc S. Williams, Angela R. Bradbury, F. Daniel Davis, Julie Hergenrather, Yirui Hu, Melissa A. Kelly, H. Lester Kirchner, Michelle N. Meyer, Jessica Mozersky, Sean M. O’Dell, Josie Pervola, Andrea Seeley…

    Citation: BMC Pediatrics 2020 20:222

    Content type: Study protocol

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  15. Relatively few studies have investigated the effects of diet on behavior problems among preschoolers, particularly, physical aggression. In addition, children raised by poorly educated mothers usually have a h...

    Authors: Wen-Chi Wu, Ching-I Lin, Yi-Fan Li, Ling-Yin Chang and Tung-liang Chiang

    Citation: BMC Pediatrics 2020 20:221

    Content type: Research article

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  16. The prevalence of food allergy (FA) has increased worldwide. In China, the prevalence of FA in infants and school-aged children is well known, but the prevalence in preschool children is unknown.

    Authors: Huan Dai, Fangmin Wang, Like Wang, Jinyi Wan, Qiangwei Xiang, Hui Zhang, Wei Zhao and Weixi Zhang

    Citation: BMC Pediatrics 2020 20:220

    Content type: Research article

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  17. Lipin-1, encoded by LPIN1 gene, serves as an enzyme and a transcriptional co-regulator to regulate lipid metabolism and mitochondrial respiratory chain. Autosomal recessive mutations in LPIN1 were recognized as o...

    Authors: Ruochen Che, Chunli Wang, Bixia Zheng, Xuejuan Zhang, Guixia Ding, Fei Zhao, Zhanjun Jia, Aihua Zhang, Songming Huang and Quancheng Feng

    Citation: BMC Pediatrics 2020 20:218

    Content type: Case report

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  18. Reducing neonatal mortality is an essential part of the third Sustainable Development Goal, to end preventable child deaths. Neonatal danger signs are the most common cause of neonatal mortality and morbidity....

    Authors: Asmamaw Demis, Getnet Gedefaw, Adam Wondmieneh, Addisu Getie and Birhan Alemnew

    Citation: BMC Pediatrics 2020 20:217

    Content type: Research article

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  19. Social skills are valid predictors for school readiness and subsequent school success. The federal state law for child day-care and preschools in Mecklenburg-Western Pomerania, a federal state in Germany, prov...

    Authors: Josefin Biermann, Marco Franze and Wolfgang Hoffmann

    Citation: BMC Pediatrics 2020 20:216

    Content type: Research article

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  20. Increasingly, neonatal mortality is concentrated in settings of conflict and political instability. To promote evidence-based practices, an interagency collaboration developed the Newborn Health in Humanitaria...

    Authors: Ribka Amsalu, Catherine N. Morris, Michelle Hynes, Hussein Jama Had, Joseph Adive Seriki, Kate Meehan, Stephen Ayella, Sammy O. Barasa, Alexia Couture, Anna Myers and Binyam Gebru

    Citation: BMC Pediatrics 2020 20:215

    Content type: Research article

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  21. Vitamin A supplementation (VAS) in the postpartum period improves the vitamin A concentration of breast milk and vitamin A status is an important predictor of childhood survival. It is also known that Vitamin ...

    Authors: Samson Gebremedhin

    Citation: BMC Pediatrics 2020 20:214

    Content type: Research article

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  22. Few clinical trials have been reported for patients with intermediate-risk neuroblastoma because of the scarcity of the disease and the variety of clinical and biological characteristics. A multidisciplinary t...

    Authors: Tomoko Iehara, Akihiro Yoneda, Atsushi Kikuta, Toshihiro Muraji, Kazuaki Tokiwa, Hideto Takahashi, Satoshi Teramukai, Tetsuya Takimoto, Shigeki Yagyu, Hajime Hosoi and Tatsuro Tajiri

    Citation: BMC Pediatrics 2020 20:212

    Content type: Study protocol

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  23. Vasovagal syncope (VVS) is common in children and significantly affects their quality of life. To our knowledge, this the first case report of SCN5A gene mutation associated with VVS and third-degree atriovent...

    Authors: Lu Gao, Xia Yu, Hongxia Li and Yue Yuan

    Citation: BMC Pediatrics 2020 20:211

    Content type: Case report

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  24. The infrared tympanic thermometer (IRTT) is a popular method for temperature screening in children, but it has been debated for the low accuracy and reproducibility compared with other measurements. This study...

    Authors: Dan Shi, Li-Yuan Zhang and Hai-Xia Li

    Citation: BMC Pediatrics 2020 20:210

    Content type: Research article

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  25. To increase the knowledge about physical activity (PA) patterns and correlates among children under the age of 4, there is a need for study’s using objective measurements. The aim of this study was therefore t...

    Authors: Linnea Bergqvist-Norén, Elin Johansson, Lijuan Xiu, Emilia Hagman, Claude Marcus and Maria Hagströmer

    Citation: BMC Pediatrics 2020 20:209

    Content type: Research article

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  26. Chronic malnutrition, often measured as stunted growth, is an understudied global health problem. Though poor nutritional intake has been linked to stunted growth, there is evidence suggesting environmental ex...

    Authors: Shanique Martin, Francis Mutuku, Julia Sessions, Justin Lee, Dunstan Mukoko, Indu Malhotra, Charles H. King and A. Desiree LaBeaud

    Citation: BMC Pediatrics 2020 20:208

    Content type: Research article

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  27. There is only limited experience with wearable cardioverter-defibrillators (WCD) in pediatric patients. We report on the successful application of a WCD in an adolescent patient with hypertrophic cardiomyopath...

    Authors: Stefan Kurath-Koller, Hannes Sallmon, Daniel Scherr, Egbert Bisping, Ante Burmas, Igor Knez and Martin Koestenberger

    Citation: BMC Pediatrics 2020 20:207

    Content type: Case report

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  28. This study objective was to evaluate the prevalence of alcohol use disorder (AUD) and related factors (smoking, internet addiction, social anxiety, child abuse, and bullying) among a representative sample of L...

    Authors: Jennifer Hallit, Pascale Salameh, Chadia Haddad, Hala Sacre, Michel Soufia, Marwan Akel, Sahar Obeid, Rabih Hallit and Souheil Hallit

    Citation: BMC Pediatrics 2020 20:205

    Content type: Research article

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  29. Kawasaki Disease (KD) is considered a major acquired heart disease in children under the age of 5. Coronary artery aneurysm (CAA) can occur in serious cases despite extreme therapy efforts. Previous studies ha...

    Authors: I-Hsin Tai, Pei-Lin Wu, Mindy Ming-Huey Guo, Jessica Lee, Chi-Hsiang Chu, Kai-Sheng Hsieh and Ho-Chang Kuo

    Citation: BMC Pediatrics 2020 20:203

    Content type: Research article

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  30. The mechanism behind idiopathic scoliosis and its progression is not fully understood. Vitamin D insufficiency is known to play a role in the progression and/or occurrence of a variety of bone diseases. In thi...

    Authors: Abdulmonem Alsiddiky, Rheema Alfadhil, Maram Al-aqel, Noura Ababtain, Norah Almajed, Khalid Bakarman, Waleed Awwad and Raheef Alatassi

    Citation: BMC Pediatrics 2020 20:202

    Content type: Research article

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  31. Monosomy 1p36 is the most common terminal deletion syndrome with an autosomal dominant pattern of inheritance. This syndrome is defined by an extremely wide spectrum of characteristics; however, developmental ...

    Authors: D. Nistico’, F. Guidolin, C. O. Navarra, M. Bobbo, A. Magnolato, A. P. D’Adamo, E. Giorgio, B. Pivetta, E. Barbi, P. Gasparini, M. Cadenaro and F. Sirchia

    Citation: BMC Pediatrics 2020 20:201

    Content type: Case report

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  32. To report the outcomes of hepatoblastoma resected in our institution.

    Authors: Jiahao Li, Huixian Li, Huiying Wu, Huilin Niu, Haibo Li, Jing Pan, Jiliang Yang, Tianbao Tan, Chao Hu, Tao Xu, Xiaohong Zhang, Manna Zheng, Kuanrong Li, Yan Zou and Tianyou Yang

    Citation: BMC Pediatrics 2020 20:200

    Content type: Research article

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  33. One major limitation for less invasive surfactant administration (LISA) is the difficulty in providing sedation before this procedure and the competitive risk of respiratory depression versus avoidance of intu...

    Authors: Marie Chevallier, Xavier Durrmeyer, Anne Ego and Thierry Debillon

    Citation: BMC Pediatrics 2020 20:199

    Content type: Study protocol

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  34. Failure to properly administer drugs to children at home may cause adverse events, which makes it a challenging job for parents or caregivers. The main goal of this study was to investigate the problems and di...

    Authors: Ra’fat Ali, Abdullah Shadeed, Hasan Fitian and Sa’ed H. Zyoud

    Citation: BMC Pediatrics 2020 20:198

    Content type: Research article

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  35. Between 1998 and 2015, we report on the survival of congenital diaphragmatic hernia (CDH)-infants presenting with symptoms within the first 24 h of life, treated at Odense University Hospital (OUH), a tertiary...

    Authors: Ulla Lei Larsen, Søren Jepsen, Thomas Strøm, Niels Qvist and Palle Toft

    Citation: BMC Pediatrics 2020 20:196

    Content type: Research article

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  36. It is important to understand the consequences of pre-emptive antibiotic treatment in neonates, as disturbances in microbiota development during this key developmental time window might affect early and later ...

    Authors: Romy D. Zwittink, Diny van Zoeren-Grobben, Ingrid B. Renes, Richard A. van Lingen, Obbe F. Norbruis, Rocio Martin, Liesbeth J. Groot Jebbink, Jan Knol and Clara Belzer

    Citation: BMC Pediatrics 2020 20:195

    Content type: Research article

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  37. Congenital central hypoventilation syndrome (CCHS) is a rare disorder characterized by respiratory system abnormalities, including alveolar hypoventilation and autonomic nervous system dysregulation. CCHS is a...

    Authors: Kelly T. Macdonald, Ricardo A. Mosquera, Aravind Yadav, Maria C. Caldas-Vasquez, Hina Emanuel and Kimberly Rennie

    Citation: BMC Pediatrics 2020 20:194

    Content type: Research article

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  38. Functional abdominal pain (FAP) disorders are one of the most common gastrointestinal disorders in children. We aimed to define the association between obesity and functional abdominal pain (FAP) disorders and...

    Authors: Tut Galai, Hadar Moran-Lev, Shlomi Cohen, Amir Ben-Tov, Dina Levy, Yael Weintraub, Achiya Amir, Or Segev and Anat Yerushalmy-Feler

    Citation: BMC Pediatrics 2020 20:193

    Content type: Research article

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  39. The present study was conducted to jointly assess some specific factors related to body fat measures using a multivariate multilevel analysis in a representative sample of Iranian mid-adolescents.

    Authors: Marzieh Alamolhoda, Seyyed Taghi Heydari, Seyyed Mohammad Taghi Ayatollahi, Reza Tabrizi, Maryam Akbari and Arash Ardalan

    Citation: BMC Pediatrics 2020 20:191

    Content type: Research article

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  40. Neurofibromatosis-Noonan syndrome (NFNS) is a rare autosomal dominant hereditary disease. We present a case of NFNS due to the heterozygous deletion of exons 1–58 of the NF1 gene on chromosome 17 in a 15-month-ol...

    Authors: Zhen Zhang, Xin Chen, Rui Zhou, Huaixiang Yin and Jiali Xu

    Citation: BMC Pediatrics 2020 20:190

    Content type: Case report

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  41. Bronchiolitis is the most common reason for infants under one year of age to be hospitalised. Despite management being well defined with high quality evidence of no efficacy for salbutamol, adrenaline, glucoco...

    Authors: Libby Haskell, Emma J. Tavender, Catherine Wilson, Franz E. Babl, Ed Oakley, Nicolette Sheridan and Stuart R. Dalziel

    Citation: BMC Pediatrics 2020 20:189

    Content type: Research article

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  42. The study evaluates children in schools that participate in the School Health Program in the Northern region of Brazil with the objective of assessing whether their schools interfered in the development of ove...

    Authors: Renata Andrade de Medeiros Moreira, Tiago Ricardo Moreira, Glauce Dias da Costa, Luiza Carla Vidigal Castro and Rosângela Minardi Mitre Cotta

    Citation: BMC Pediatrics 2020 20:188

    Content type: Research article

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