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  1. Children with transfusion-dependent thalassemia (TDT) suffer from secondary hemosiderosis and the delirious effects this iron overload has on their different body organs, including the pancreas. They are also ...

    Authors: Suzan O. Mousa, Ebtihal M. Abd Alsamia, Hend M. Moness and Osama G. Mohamed

    Citation: BMC Pediatrics 2021 21:468

    Content type: Research

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  2. Over 90% of the 50,000 deaf children in the UK have hearing parents, many of whom were not expecting a deaf child and may require specialist support. Deaf children can experience poorer long-term outcomes than...

    Authors: B. Wright, R. Hargate, M. Garside, G. Carr, T. Wakefield, R. Swanwick, I. Noon and P. Simpson

    Citation: BMC Pediatrics 2021 21:467

    Content type: Research

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  3. Correction surgery for cleft palate is recommended between 9 and 18 months of age. Patients suffer from acute pain after palatoplasty. Clinicians are hesitant to use opioids for analgesia concerning the potent...

    Authors: Zhe Zhe Peng, Yan Ting Wang, Ma Zhong Zhang, Ji Jian Zheng, Jie Hu, Wan Ru Zhou and Ying Sun

    Citation: BMC Pediatrics 2021 21:466

    Content type: Research

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  4. This retrospective study aimed to determine the epidemiological features of deaths caused by unintentional suffocation among infants in China.

    Authors: Xue Yu, Lei Miao, Jun Zhu, Juan Liang, Li Dai, Xiaohong Li, Qi Li, Rui Rao, Chunhua Yuan, Yanping Wang, Chunhua He and Leni Kang

    Citation: BMC Pediatrics 2021 21:465

    Content type: Research article

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  5. The aim of this study was to summarize the clinical characteristics, therapeutic effects and prognosis of patients with rhabdomyosarcoma (RMS) and bone marrow metastasis, improve the understanding of this dise...

    Authors: Cheng Huang, Binglin Jian, Yan Su, Na Xu, Tong Yu, Lejian He, Xue Zhang, Yi Liu, Mei Jin and Xiaoli Ma

    Citation: BMC Pediatrics 2021 21:463

    Content type: Research

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  6. Disasters can have deep physical and psychological impact among survivors. An extraordinary southwest monsoon has unleashed floods and landslides in Kerala state in 2018. Adolescents are more vulnerable to psy...

    Authors: Geethu Mathew, Aby Dany Varghese, Ans Mary Sabu and Aleena Joseph

    Citation: BMC Pediatrics 2021 21:462

    Content type: Research

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  7. Evidence for peritoneal dialysis catheter (PDC) usage in pediatric patients undergoing surgery for deteriorating cardiac dysfunction is lacking. This investigation explored factors associated with PDC usage an...

    Authors: Chunrong Wang, Yuefu Wang, Fuxia Yan, Peng Fu, Jun Li, Lijing Yang, Sheng Shi, Jianhui Wang, Yuchen Gao, Sudena Wang and Yu Tian

    Citation: BMC Pediatrics 2021 21:461

    Content type: Research article

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  8. Right-sided congenital diaphragmatic hernia (RCDH) is relatively rare compared with left-sided congenital diaphragmatic hernia (LCDH). Clinical data of RCDH, especially with respect to antenatal prediction of ...

    Authors: Jiyoon Jeong, Byong Sop Lee, Teahyen Cha, Euiseok Jung, Ellen Ai-Rhan Kim, Ki-Soo Kim, Dae Yeon Kim, Jung-Man Namgoong, Seong Chul Kim, Mi-Young Lee and Hye-Sung Won

    Citation: BMC Pediatrics 2021 21:460

    Content type: Research

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  9. There are differences in roles between the more-affected and less-affected upper limb of children with cerebral palsy (CP). However, there is a lack of studies of the relationship between the more-affected lim...

    Authors: Hyerin Park, Ja Young Choi, Sook-hee Yi, Eun Sook Park, Dain Shim, Tae Young Choi and Dong-wook Rha

    Citation: BMC Pediatrics 2021 21:459

    Content type: Research

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  10. The differentiation between systemic inflammatory response syndrome and sepsis is very important as it determines essential treatment decisions, such as selection, initiation, and duration of antibiotic therapy.

    Authors: Noha A. Hassuna, Ebtesam Elgezawy, Suzan O. Mousa, Reem A. AbdelAziz, Reham A. Ibrahem, Wafaa Yousif Abdel Wahed, Khalid A. Nasif and Enas M. Hefzy

    Citation: BMC Pediatrics 2021 21:458

    Content type: Research

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  11. Optimal management of haemodynamically significant patent ductus arteriosus (HsPDA) in premature babies remains controversial. Our aim is to compare death and/or adverse neurodevelopmental outcomes in extremel...

    Authors: Jania Jia-Ying Wu, Krishnamoorthy Niduvaje, Le ye Lee and Zubair Amin

    Citation: BMC Pediatrics 2021 21:457

    Content type: Research article

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  12. Children with cerebral palsy (CP) frequently experience chronic pain. The burden and severity of such pain is often underestimated in relation to their other impairments. Recognition and awareness of this chro...

    Authors: Emma Nsalazi Bambi, Angelina Kakooza Mwesige, Hervé Monka Lekuya, Philip Kasirye and Richard Idro

    Citation: BMC Pediatrics 2021 21:456

    Content type: Research

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  13. In Lebanon, divorce rates have jumped from nearly 7000 in recent years to 8580 in 2017, an increase of 22.5%, with North Lebanon recording the highest number, followed by Beirut, likely resulting in increased ...

    Authors: Sahar Obeid, Gloria Al Karaki, Chadia Haddad, Hala Sacre, Michel Soufia, Rabih Hallit, Pascale Salameh and Souheil Hallit

    Citation: BMC Pediatrics 2021 21:455

    Content type: Research article

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  14. Severe protein C deficiency is a rare and inherited cause of thrombophilia in neonates. Protein C acts as an anticoagulant, and its deficiency results in vascular thrombosis. Herein, we report a case of protei...

    Authors: Uisook Song, Young Hye Ryu, Kiteak Hong, So-Yeon Shim, Seongyeol Park, Jeong Seok Lee, Young Seok Ju, Seung Han Shin and Soyoung Lee

    Citation: BMC Pediatrics 2021 21:453

    Content type: Case report

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  15. Children from socioeconomically disadvantaged families have a markedly elevated risk for impaired cognitive and social-emotional development. Children in poverty experience have a high risk for developmental d...

    Authors: Katherine Bowers, Lili Ding, Kimberly Yolton, Hong Ji, Nichole Nidey, Jerrold Meyer, Robert T. Ammerman, Judith Van Ginkel and Alonzo Folger

    Citation: BMC Pediatrics 2021 21:452

    Content type: Research

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  16. Oxygen therapy is a lifesaving treatment, however, in Ethiopia, oxygen is not readily available in many healthcare facilities. In 2015, the Federal Ministry of Health launched a national roadmap to increase ac...

    Authors: Habtamu Seyoum Tolla, Yigeremu Abebe Asemere, Alebel Yaregal Desale, Dinkineh Bikila Woyessa, Zinabie Feleke Fekadu, Alemayehu Berhanu Belete, Audrey Battu and Felix Lam

    Citation: BMC Pediatrics 2021 21:451

    Content type: Research article

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  17. Mongolian traditional swaddling of infants, where arms and legs are extended with a tight wrapping and hips are in adduction position, may lead to abnormal maturation and formation of the hip joint; and is a c...

    Authors: Munkhtulga Ulziibat, Bayalag Munkhuu, Ariun-Erdene Bataa, Raoul Schmid, Thomas Baumann and Stefan Essig

    Citation: BMC Pediatrics 2021 21:450

    Content type: Research

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  18. Chylomicron retention disease (Anderson disease) is a result for variant of the SAR1B gene. It is a rare autosomal recessive hereditary disorder with most incidence in infant. It is characterized by lipid mala...

    Authors: Leen Jamel Doya, Lava Mohammad, Razan Omran, Alexander Ali Ibrahim, Nizar Yousef, Ali Ibrahim and Mohammad Adib Houreih

    Citation: BMC Pediatrics 2021 21:449

    Content type: Case report

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  19. Granulomatous capillary haemangioma refers to a benign vascular tumour that commonly affects the skin, with occasional involvement of the mucosa. Reports of conjunctival granulomatous capillary haemangioma in ...

    Authors: Caiping Shi, Yanhong Ren, Jia Feng, Weizhong Guo and Xiaoyu Zheng

    Citation: BMC Pediatrics 2021 21:448

    Content type: Case report

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  20. The implementation of genomic testing in pregnancy means that couples have access to more information about their child’s genetic make-up before birth than ever before. One of the resulting challenges is the m...

    Authors: Lisa Hui, Cecilia Pynaker, Joanne Kennedy, Sharon Lewis, David J. Amor, Susan P. Walker and Jane Halliday

    Citation: BMC Pediatrics 2021 21:447

    Content type: Study protocol

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  21. The fat mass estimators waist-to-height ratio (WHtR) and relative fat mass—pediatric (RFMp) complement the widely accepted body mass index (BMI) in obesity evaluation. Aims of the Study: Conduct an easy apprai...

    Authors: Manuel Moya and Virginia Pérez-Fernandez

    Citation: BMC Pediatrics 2021 21:446

    Content type: Research article

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  22. Haematopoietic stem cell transplantation (HSCT) is used worldwide in various malignant and nonmalignant childhood diseases, including haematologic, genetic, autoimmune and metabolic disorders, and is the only ...

    Authors: Ali Önder Atça, Berrin Erok and Selime Aydoğdu

    Citation: BMC Pediatrics 2021 21:445

    Content type: Research

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  23. Congenital disorders of glycosylation (CDG) are a group of metabolic diseases with clinical and genetic heterogeneity, and CDG-IIg is one of the rare reported types of CDG. The aim of this study is to report t...

    Authors: Yizhou Huang, Han Dai, Gangyi Yang, Lili Zhang, Shiyao Xue and Min Zhu

    Citation: BMC Pediatrics 2021 21:442

    Content type: Case report

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  24. We admitted a child with a duplex kidney combined with preoperative rupture of nephroblastoma and used this case to discuss the clinical features and treatment of this disease.

    Authors: Yongxiang Zhao, Haiyan Cheng, Hongcheng Song, Ruimin Zhang, Xiangming Wu, Haowei Li, Jun Wang, Huanmin Wang and Chunmei Jia

    Citation: BMC Pediatrics 2021 21:441

    Content type: Case report

    Published on:

  25. Conventional diffusion weighted imaging (DWI) is a promising non-invasive tool in the evaluation of infants with symptomatic urinary tract infections (UTI). The use of multiparametric diffusion tensor imaging ...

    Authors: Yvonne Simrén, Eira Stokland, Sverker Hansson, Hanna Hebelka, Par-Arne Svensson and Kerstin M. Lagerstrand

    Citation: BMC Pediatrics 2021 21:440

    Content type: Research article

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  26. Neonatal mortality can be reduced by providing essential newborn care. However, it is overlooked by most healthcare providers in Ethiopia. Hence, this study aims to examine immediate essential newborn care pra...

    Authors: Ermias Sisay Chanie, Amare Kassaw, Melkamu Senbeta, Fisha Alebel GebreEyesus, Aragaw Tesfaw, Abenezer Melkie, Tekalign Amera Birlie, Biruk Demissie, Demeke Mesfin Belay, Demewoze Kefale Mekone, Biniam Minuye Birhan and Wubet Alebachew Bayih

    Citation: BMC Pediatrics 2021 21:439

    Content type: Research

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  27. Children with a low socio-economic position (SEP) participate in prevention and health examinations less often. In order to increase participation, reminder systems have been implemented in Germany since 2009....

    Authors: Simone Weyers, Annika Höhmann, Simon Götz and Katharina Kreffter

    Citation: BMC Pediatrics 2021 21:438

    Content type: Research article

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  28. Anastomotic or perianastomotic ulcers present with symptoms such as chronic anaemia and occult bleeding as long-term complications of bowel resection performed in infancy.

    Authors: Maho Iwamoto, Tsugumichi Koshinaga, Eri Fujita, Manabu Hanada, Shuichiro Uehara and Mitsuhiko Moriyama

    Citation: BMC Pediatrics 2021 21:437

    Content type: Case report

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  29. The safety and feasibility of stapled intestinal anastomosis have been widely reported in adults. However, the efficacy of stapled anastomosis (SA) in children is unclear. The aim of this study was to perform ...

    Authors: Takayuki Fujii, Aya Tanaka, Hiroto Katami and Ryuichi Shimono

    Citation: BMC Pediatrics 2021 21:435

    Content type: Research article

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  30. The public health burden of undernutrition remains heavy and widespread, especially in low-income countries like Nepal. While predictors of undernutrition are well documented, few studies have examined the eff...

    Authors: Grace Namirembe, Robin Shrestha, Julieta Mezzano, Lynne M. Ausman, Dale Davis, Kedar Baral, Shibani Ghosh, Gerald Shively and Patrick Webb

    Citation: BMC Pediatrics 2021 21:434

    Content type: Research

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  31. Globally, approximately 4.1 million infants died, accounting for 75% of all under-five deaths. In sub-Saharan Africa (SSA), infant mortality was 52.7/1000 live births in 2018 This study aimed to assess the poo...

    Authors: Sofonyas Abebaw Tiruneh, Ejigu Gebeye Zeleke and Yaregal Animut

    Citation: BMC Pediatrics 2021 21:433

    Content type: Research

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  32. Anti-seizure medication (ASM) treatment is one of the significant risk factors associated with abnormal vitamin D status in epilepsy patients. Multiple studies have shown that adult epilepsy patients can exhib...

    Authors: Napakjira Likasitthananon, Charcrin Nabangchang, Thitiwan Simasathien, Suchavadee Vichutavate, Voraluck Phatarakijnirund and Piradee Suwanpakdee

    Citation: BMC Pediatrics 2021 21:432

    Content type: Research

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  33. Few treatments exist for adolescents living with severe obesity. This qualitative study explored the experiences of severely obese adolescents and their families who participated in the BOB study.

    Authors: Lindsey J. Reece, Paul Bissell, Pooja Sachdev, Neil Wright, Seema Mihrshahi and Robert J. Copeland

    Citation: BMC Pediatrics 2021 21:431

    Content type: Research

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  34. Children with severe congenital heart disease (CHD) are a group of children at risk for neurodevelopmental impairments. Motor development is the first domain to show a delay during the first year of life and m...

    Authors: Elena Mitteregger, Martina Wehrli, Manuela Theiler, Jana Logoteta, Irina Nast, Brigitte Seliner and Beatrice Latal

    Citation: BMC Pediatrics 2021 21:430

    Content type: Research article

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  35. Z score utility is emphasized in classifying coronary artery lesions in Kawasaki disease patients. The present study is the largest such multicenter Chinese pediatric study about coronary artery diameter refere.....

    Authors: Shu-min Fan, Bei Xia, Wei-xiang Liu, Wei Yu, Zhi-xia Wu, Shu-Bao Chen, Qing-Hua Liu, Wen-juan Chen, Shan-liang Zhu, Mei Jin, Jie-Qing Min and Yang Xu

    Citation: BMC Pediatrics 2021 21:429

    Content type: Research

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  36. Although chronic pain is common in children with cerebral palsy (CP), little is known about short-term pain fluctuations and their impact on children’s well-being. High-quality cohort studies are needed to und...

    Authors: Heather M. Shearer, Pierre Côté, Sheilah Hogg-Johnson, Patricia McKeever and Darcy L. Fehlings

    Citation: BMC Pediatrics 2021 21:428

    Content type: Research

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  37. Dexamethasone, a highly effective drug in treating pediatric acute lymphoblastic leukemia (ALL), can induce serious neurobehavioral side effects. These side effects are experienced by patients and parents as d...

    Authors: A. M. van Hulst, E. J. Verwaaijen, M. F. Fiocco, S. M. F. Pluijm, M. A. Grootenhuis, R. Pieters, E. L. T. van den Akker and M. M. van den Heuvel-Eibrink

    Citation: BMC Pediatrics 2021 21:427

    Content type: Study protocol

    Published on:

  38. Exploring the impact of injury and injury severity on academic outcomes could assist to identify characteristics of young people likely to require learning support services. This study aims to compare scholast...

    Authors: Rebecca J. Mitchell, Cate M. Cameron, Anne McMaugh, Reidar P. Lystad, Tim Badgery-Parker and Tayhla Ryder

    Citation: BMC Pediatrics 2021 21:426

    Content type: Research

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  39. Injury is the leading cause of death among Saudi children. Despite that, much remains unknown on the epidemiology and the extent of burden. This scoping review aims to describe previous literature on injury bu...

    Authors: Hadeel Albedewi, Nouf Al-Saud, Abdulhameed Kashkary, Ada Al-Qunaibet, Salem M. AlBalawi and Suliman Alghnam

    Citation: BMC Pediatrics 2021 21:424

    Content type: Research

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  40. Urinary iodine is recommended by the world health organization as the main indicator to assess iodine status in a population. Despite this recommendation little is known about urinary iodine concentration in t...

    Authors: Birtukan Shiferaw Ayalew, Seid Legesse Hassen, Tefera Alemu Marefiyaw, Mohammed Seid Yesuf, Daniel Dagne Abebe and Minwuyelet Maru Temesgen

    Citation: BMC Pediatrics 2021 21:423

    Content type: Research

    Published on:

  41. The growing number of adolescents who are overweight or obese (OW / OB) is a public concern. The present study was aimed to evaluate physical activity (PA) and sedentary behaviors (SB) (screen time (ST) and ho...

    Authors: Ali Mohammad Hadianfard, Hassan Mozaffari-Khosravi, Majid Karandish and Maryam Azhdari

    Citation: BMC Pediatrics 2021 21:421

    Content type: Research

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  42. Recommendations for endotracheal tube (ETT) size usually refer to the inner diameter (ID). Outer diameters (OD), however, vary greatly between manufacturers, which in some brands might cause difficulties in pa...

    Authors: Bianca Haase, Ana-Maria Badinska, Christian A. Maiwald, Christian F. Poets and Laila Springer

    Citation: BMC Pediatrics 2021 21:417

    Content type: Research

    Published on:

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