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  1. Propionic acidemia (PA) and methylmalonic acidemia (MMA) are rare autosomal recessive inborn errors of metabolism characterized by hyperammonemia due to N-acetylglutamate synthase (NAGS) dysfunction. Carglumic...

    Authors: Marwan Nashabat, Abdulrahman Obaid, Fuad Al Mutairi, Mohammed Saleh, Mohammed Elamin, Hind Ahmed, Faroug Ababneh, Wafaa Eyaid, Abdulrahman Alswaid, Lina Alohali, Eissa Faqeih, Majed Aljeraisy, Mohamed A. Hussein, Ali Alasmari and Majid Alfadhel
    Citation: BMC Pediatrics 2019 19:195
  2. The short-term effects of particulate matter (PM) exposure on childhood asthma exacerbation and disease control rate is not thoroughly assessed in Chinese population yet. The previous toxic effects of PM expos...

    Authors: Jinzhun Wu, Taoling Zhong, Yu Zhu, Dandan Ge, Xiaoliang Lin and Qiyuan Li
    Citation: BMC Pediatrics 2019 19:194
  3. Rotavirus antigenemia and RNAemia (the presence of rotavirus RNA in serum) have been commonly identified among paediatric patients with acute gastroenteritis. In this study we examined the association between ...

    Authors: Maria Cleonice A. Justino, Erika A. Campos, Joana D’arc P. Mascarenhas, Luana S. Soares, Sylvia de Fátima S. Guerra, Ismari P. Furlaneto, Manoel Jaime C. Pavão Jr, Tassio S. Maciel, Fredison P. Farias, Orvácio M. Bezerra, Caio Breno G. Vinente, Rodrigo José S. Barros and Alexandre C. Linhares
    Citation: BMC Pediatrics 2019 19:193
  4. In response to multiple United Kingdom investigations and inquiries into the care of adults with learning disabilities, Mencap produced the Getting it Right Charter which campaigned for the appointment of a Le...

    Authors: Kate Oulton, Jo Wray, Angela Hassiotis, Charlotte Kenten, Jessica Russell, Irene Tuffrey-Wijne, Mark Whiting and Faith Gibson
    Citation: BMC Pediatrics 2019 19:192
  5. The diagnosis of cow’s milk protein allergy(CMPA) may be easily misdiagnosed due to its lack of specific symptoms. Thus, experts have proposed the use of Cow’s milk-related symptom scores (CoMiSS) to predict C...

    Authors: Yongmei Zeng, Jiyong Zhang, Guoqing Dong, Peihui Liu, Fei Xiao, Weiyan Li, Liting Wang and Qianzhen Wu
    Citation: BMC Pediatrics 2019 19:191
  6. One in three Head Start children is either overweight or obese. We will test the efficacy of an early childhood obesity prevention program, “¡Míranos! Look at Us, We Are Healthy!” (¡Míranos!), which promotes heal...

    Authors: Zenong Yin, Sarah L. Ullevig, Erica Sosa, Yuanyuan Liang, Todd Olmstead, Jeffrey T. Howard, Vanessa L. Errisuriz, Vanessa M. Estrada, Cristina E. Martinez, Meizi He, Sharon Small, Cindy Schoenmakers and Deborah Parra-Medina
    Citation: BMC Pediatrics 2019 19:190
  7. Neutrophils and eosinophils are multifunctional granulocytes derived from common myelocytic-committed progenitor cells. Severe congenital neutropenia 1 (SCN1) caused by ELANE mutations is a rare disease character...

    Authors: Qiao Liu, Martina Sundqvist, Wenyan Li, André Holdfeldt, Liang Zhang, Lena Björkman, Johan Bylund, Claes Dahlgren, Cai Wang, Xiaodong Zhao and Huamei Forsman
    Citation: BMC Pediatrics 2019 19:189
  8. In Indonesia, the burden of severe hyperbilirubinemia is higher compared to other countries. Whether this is related to ineffective phototherapy (PT) is unknown. The aim of this study is to investigate the per...

    Authors: Mahendra T. A. Sampurna, Kinanti A. Ratnasari, Darto Saharso, Arend F. Bos, Pieter J. J. Sauer, Peter H. Dijk and Christian V. Hulzebos
    Citation: BMC Pediatrics 2019 19:188
  9. Despite the fact that several scabies outbreaks emerged in schools in Saudi Arabia in 2018, no study has investigated the risk of scabies recurrence among children in Saudi Arabia. This study aimed to estimate...

    Authors: Anwar E. Ahmed, Hoda Jradi, Doaa A. AlBuraikan, Bashayr I. ALMuqbil, Monirah A. Albaijan, Ali M. Al-Shehri and Hamdan AL-Jahdali
    Citation: BMC Pediatrics 2019 19:187
  10. It is known that obesity is associated with vitamin D deficiency and observational studies have shown vitamin D deficiency to be linked with the development of type 2 diabetes. There are no comprehensive data ...

    Authors: S. G. S. Adikaram, D. B. D. L. Samaranayake, N. Atapattu, K. M. D. L. D. Kendaragama, J. T. N. Senevirathne and V. Pujitha Wickramasinghe
    Citation: BMC Pediatrics 2019 19:186
  11. Probiotic therapy can reduce the incidence of NEC. Therapeutic use of probiotics after NEC diagnosis reduces the severity of NEC in preterm infants or full-term infants is unclear. To evaluate the effect of pr...

    Authors: Zheng-Li Wang, Li Liu, Xiao-Yu Hu, Lu Guo, Qiu-Yu Li, Yao An, Ya-Jun Jiang, Shi Chen, Xue-Qiu Wang, Yu He and Lu-Quan Li
    Citation: BMC Pediatrics 2019 19:185
  12. Television (TV) viewing may affect children’s obesity status. In the present study the association between TV viewing and early childhood overweight/obese status was investigated as well as the association bas...

    Authors: Jiajin Hu, Ning Ding, Liu Yang, Yanan Ma, Ming Gao and Deliang Wen
    Citation: BMC Pediatrics 2019 19:184
  13. Neonatal renal vein thrombosis is a recognised cause of renal and inferior caval vein atresia (IVCA). However, the long-term impact of the condition is underrecognized with a high burden of morbidity for the p...

    Authors: Stefan Lauener, Anne Bütikofer, Sandra Eigenheer and Robert Escher
    Citation: BMC Pediatrics 2019 19:183
  14. Stunting in developing countries continues to be a major public health problem. Measuring head circumference (HC) during clinical anthropometric assessment can help predict stunting. The aim of this study was ...

    Authors: Kulandaipalayam Natarajan Sindhu, Prashanth Ramamurthy, Karthikeyan Ramanujam, Ankita Henry, Joseph Dian Bondu, Sushil Mathew John, Sudhir Babji, Beena Koshy, Anuradha Bose, Gagandeep Kang and Venkata Raghava Mohan
    Citation: BMC Pediatrics 2019 19:182
  15. Invasive S. pyogenes diseases are uncommon, serious infections with high case fatality rates (CFR). There are few publications on this subject in the field of pediatrics. This study aimed at characterizing clinic...

    Authors: Chun-Zhen Hua, Hui Yu, Hong-Mei Xu, Lin-Hai Yang, Ai-Wei Lin, Qin Lyu, Hong-Ping Lu, Zhi-Wei Xu, Wei Gao, Xue-jun Chen, Chuan-Qing Wang and Chun-mei Jing
    Citation: BMC Pediatrics 2019 19:181
  16. Despite growing interest in universal screening for congenital CMV infection (cCMV), and data to support treatment for cases with central nervous system (CNS) involvement, there is limited regarding the optima...

    Authors: Mina Smiljkovic, Christian Renaud, Bruce Tapiero, Valérie Lamarre and Fatima Kakkar
    Citation: BMC Pediatrics 2019 19:180
  17. Infants with hemodynamically significant patent ductus arteriosus (PDA) may physiologically compensate with a supranormal cardiac output (CO). As such, a supranormal CO may be a surrogate marker for a signific...

    Authors: Kai-Hsiang Hsu, Tai-Wei Wu, I-Hsyuan Wu, Mei-Yin Lai, Shih-Yun Hsu, Hsiao-Wen Huang, Tze-Yee Mok, Cheng-Chung Lee and Reyin Lien
    Citation: BMC Pediatrics 2019 19:179
  18. A hospitalized patient’s length of stay (LOS) can have a significant impact on the performance and operating costs of a healthcare facility. Among pediatric patients, traumatic injuries are common causes of em...

    Authors: Suliman Alghnam, Jawaher Ali Towhari, Ibrahim Al Babtain, Muhannad Al Nahdi, Mohammed Hamad Aldebasi, Mahna Alyami and Hamad Alkhalaf
    Citation: BMC Pediatrics 2019 19:177
  19. Childhood stunting is the most widely prevalent among under-five children in Ethiopia. Despite the individual-level factors of childhood stunting are well documented, community-level factors have not been give...

    Authors: K. Fantay Gebru, W. Mekonnen Haileselassie, A. Haftom Temesgen, A. Oumer Seid and B. Afework Mulugeta
    Citation: BMC Pediatrics 2019 19:176
  20. Prolonged neonatal jaundice (PNNJ) is often caused by breast milk jaundice, but it could also point to other serious conditions (biliary atresia, congenital hypothyroidism). When babies with PNNJ receive a rou...

    Authors: Hui-Siu Tan, Inthira-Sankari Balasubramaniam, Amar-Singh HSS, May-Luu Yeong, Chii-Chii Chew, Ranjit-Kaur Praim Singh, Ai-Yuin Leow, Fatimahtuz-Zahrah Muhamad Damanhuri and Santhi Verasingam
    Citation: BMC Pediatrics 2019 19:174
  21. Following publication of the original article [1], the authors reported error on the images/figures used which also resulted in un-sequential order. The updated figures and captions are provided below.

    Authors: Fereshteh Salimi Jazi, Julia M. Chandler, Chad M. Thorson, Tiffany J. Sinclair, Florette K. Hazard, John A. Kerner, Sanjeev Dutta, James C. Y. Dunn and Stephanie D. Chao
    Citation: BMC Pediatrics 2019 19:172

    The original article was published in BMC Pediatrics 2019 19:93

  22. To evaluate the accuracy of motor assessment tools listed in Fetal alcohol spectrum disorder: a guideline for diagnosis across the lifespan (Canadian Guideline) for the purpose of fetal alcohol spectrum disorder ...

    Authors: Danielle Johnston, Erin Branton, Leah Rasmuson, Sylvia Schell, Douglas P. Gross and Lesley Pritchard-Wiart
    Citation: BMC Pediatrics 2019 19:171
  23. Insufficient elastin synthesis leads to vascular complications and arterial hypertension in children with Williams-Beuren syndrome. Restoring sufficient quantity of elastin should then result in prevention or ...

    Authors: Behrouz Kassai, Philippe Bouyé, Brigitte Gilbert-Dussardier, François Godart, Jean-Benoit Thambo, Massimiliano Rossi, Pierre Cochat, Pierre Chirossel, Stephane Luong, André Serusclat, Isabelle Canterino, Catherine Mercier, Muriel Rabilloud, Christine Pivot, Fabrice Pirot, Tiphanie Ginhoux…
    Citation: BMC Pediatrics 2019 19:170
  24. Dog bite injuries are an ongoing concern in pediatrics. The majority of these occur in low- and middle-income countries where resources, especially subspecialty support services, are limited. Scrotal bites are...

    Authors: Edwin S. Palmer, Phitsavanh Saysamoneyeu, Jennifer M. Siu, Annkham Thammaseng and Indi Trehan
    Citation: BMC Pediatrics 2019 19:169
  25. 2500 g has been used worldwide as the definition of low birthweight (LBW) for almost a century. While previous studies have used statistical approaches to define LBW cutoffs, a LBW definition using an outcome-...

    Authors: Malinee Laopaiboon, Pisake Lumbiganon, Siwanon Rattanakanokchai, Warut Chaiwong, João Paulo Souza, Joshua P. Vogel, Rintaro Mori and Ahmet Metin Gülmezoglu
    Citation: BMC Pediatrics 2019 19:166
  26. Non-supine infant sleep position is an important modifiable risk factor for sudden unexpected death in infancy. The aim of this study was to assess the prevalence of supine sleep position and associated factor...

    Authors: Bruna Gonçalves C. da Silva, Mariângela Freitas da Silveira, Paula Duarte de Oliveira, Marlos Rodrigues Domingues, Nelson Arns Neumann, Fernando C. Barros and Andréa Dâmaso Bertoldi
    Citation: BMC Pediatrics 2019 19:165
  27. Migraine is a disabling primary headache disorder that occurs in about 10 % of children and might lead to a lower quality of life. There are several possible migraine triggers in a patient’s environment, which...

    Authors: Lydia Stella Koller, Susanne C. Diesner and Peter Voitl
    Citation: BMC Pediatrics 2019 19:164
  28. Chronic suppurative otitis media (CSOM) causes preventable deafness and disproportionately affects children living in poverty. Our hypothesis was that health promotion in women’s groups would increase their kn...

    Authors: Susan Clarke, Robyn Richmond, Heather Worth, Rajendra Wagle and Andrew Hayen
    Citation: BMC Pediatrics 2019 19:163
  29. Detecting and addressing aspiration early in children with dysphagia, such as those with cerebral palsy, is important for preventing aspiration pneumonia. The current gold standards for assessing aspiration ar...

    Authors: Nobukazu Tanaka, Kanji Nohara, Akihito Ueda, Tamami Katayama, Miyuki Ushio, Nami Fujii and Takayoshi Sakai
    Citation: BMC Pediatrics 2019 19:162
  30. Hypertension is an emerging disease in children and adolescents resulting in future morbidities. Cigarette smoking is one of the most studied contributing factors in this regard; however, there are contradicto...

    Authors: Mahshid Aryanpur, Mahmoud Yousefifard, Alireza Oraii, Gholamreza Heydari, Mehdi Kazempour-Dizaji, Hooman Sharifi, Mostafa Hosseini and Hamidreza Jamaati
    Citation: BMC Pediatrics 2019 19:161
  31. Unsettled infant behaviours are a common concern for parents internationally, and have been associated with maternal stress, reduced parenting confidence, and postnatal mental health problems among parents. Li...

    Authors: Linda Murray, Thach Tran, Vo Van Thang, Nicole McDonald, Sean Beggs and Jane Fisher
    Citation: BMC Pediatrics 2019 19:160
  32. There is limited information available regarding the clinical management of intravenous immunoglobulin-resistant Kawasaki disease (KD). We aimed to evaluate the optimal treatment options for patients with refr...

    Authors: Han Chan, Huan Chi, Hui You, Mo Wang, Gaofu Zhang, Haiping Yang and Qiu Li
    Citation: BMC Pediatrics 2019 19:158
  33. Schoolbags and the consequences of carrying them, particularly those associated with overload, are often studied as a health concern. Modifications in gait and posture were reported when children carried loads...

    Authors: João Barbosa, Mário C. Marques, Mikel Izquierdo, Henrique P. Neiva, Tiago M. Barbosa, Robinson Ramírez-Vélez, Alicia M. Alonso-Martínez, Antonio García-Hermoso, Roberto Aguado-Jimenez and Daniel A. Marinho
    Citation: BMC Pediatrics 2019 19:157
  34. Although various studies have shown the effect of vigorous physical activity on academic achievements, no studies have investigated the effect of vitamin E levels on academic performance. The present study aim...

    Authors: Ahmad H. Alghadir, Sami A. Gabr, Zaheen A. Iqbal and Einas Al-Eisa
    Citation: BMC Pediatrics 2019 19:156
  35. Neurally adjusted ventilatory assist (NAVA) is an alternative to pressure support ventilation (PSV) potentially improving patient-ventilator interaction. During NAVA, diaphragmatic electrical activity (EAdi) i...

    Authors: Thomas Langer, Serena Baio, Giovanna Chidini, Tiziana Marchesi, Giacomo Grasselli, Antonio Pesenti and Edoardo Calderini
    Citation: BMC Pediatrics 2019 19:155
  36. Sedentary behaviour has become a growing public health concern. Currently, it is a common belief that screen time (SCT) is a key factor in high overall sedentary time (ST) and is often used as a primary outcom...

    Authors: Belinda Hoffmann, Susanne Kobel, Olivia Wartha, Sarah Kettner, Jens Dreyhaupt and Jürgen M. Steinacker
    Citation: BMC Pediatrics 2019 19:154
  37. Pediatricians are advised by the Austrian ministry of health to be vaccinated against diphtheria, tetanus, pertussis, poliomyelitis, measles, mumps, rubella, varicella, hepatitis A, hepatitis B, meningococcus ...

    Authors: Susanne C. Diesner, Sarah Peutlberger and Peter Voitl
    Citation: BMC Pediatrics 2019 19:153
  38. As the pediatric population requiring health services rises globally, developing countries are struggling to cater to the growing burden of non-communicable diseases - particularly those requiring specialized ...

    Authors: Amir Humza Sohail, Muhammad Hassaan Arif Maan, Mohammed Sachal and Muhammad Soban
    Citation: BMC Pediatrics 2019 19:152
  39. Following publication of the original article [1], the authors reported that an out-of-date version of Figure 1 had been incorporated in the published article.

    Authors: Timothy Hahn, Whitney Adams and Keith Williams
    Citation: BMC Pediatrics 2019 19:151

    The original article was published in BMC Pediatrics 2019 19:74

  40. Childhood unintentional injuries (UI) are common but continue to happen more often to children living in less advantaged socioeconomic circumstances (SEC). Our aim was to explore how early life factors mediate...

    Authors: M. Campbell, E. T. C. Lai, A. Pearce, E. Orton, D. Kendrick, S. Wickham and D. C. Taylor-Robinson
    Citation: BMC Pediatrics 2019 19:150
  41. Maternal alcohol consumption in pregnancy may have adverse effects on child gross motor (GM) development. There have been few human studies on this topic, particularly ones examining low exposure. This study e...

    Authors: Delyse Hutchinson, George J. Youssef, Clare McCormack, Judy Wilson, Steve Allsop, Jake Najman, Elizabeth Elliott, Lucinda Burns, Sue Jacobs, Ingrid Honan, Larissa Rossen, Hannah Fiedler, Samantha Teague, Joanne Ryan, Craig A. Olsson and Richard P. Mattick
    Citation: BMC Pediatrics 2019 19:149

    The Correction to this article has been published in BMC Pediatrics 2019 19:222

  42. The prevalence of asthma and obesity have increased over the last decades. A possible association between these two chronic illnesses has been suggested, since the prevalence of asthmatic symptoms rises with i...

    Authors: Yvette E. Lentferink, Nienke E. Boogaart, Walter A. F. Balemans, Catherijne A. J. Knibbe and Marja M. J. van der Vorst
    Citation: BMC Pediatrics 2019 19:148

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