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  1. Polycystic ovary syndrome is the most common endocrine disorder among adolescents and adults. Given the importance of healthy nutritional behaviors in management of this disease, the present study was conducte...

    Authors: Leila Hajivandi, Mahnaz Noroozi, Firoozeh Mostafavi and Maryam Ekramzadeh
    Citation: BMC Pediatrics 2021 21:316
    Content type: Research article Published on:

  3. Near-infrared spectroscopy (NIRS) measures of cerebral saturation (Csat) and renal saturation (Rsat) in extreme premature newborns may be affected by systemic blood flow fluctuations. Despite increasing clinic...

    Authors: Gabriel Altit, Shazia Bhombal and Valerie Y. Chock
    Citation: BMC Pediatrics 2021 21:312
    Content type: Research Published on:

  4. Little is known about the factors associated with the World Health Organization (WHO) recommendation of breastfeeding for at least 2 years. The objective of this study was to identify risk factors for and prot...

    Authors: Graciete Oliveira Vieira, Tatiana de Oliveira Vieira, Camilla da Cruz Martins, Michelle de Santana Xavier Ramos and Elsa Regina Justo Giugliani
    Citation: BMC Pediatrics 2021 21:310
    Content type: Research Published on:

  5. When evaluating speech in children with cleft palate with or without cleft lip (CP/L), children with known syndromes and/or additional malformations (CP/L+) are usually excluded. The aim of this study was to p...

    Authors: Kristina Klintö, Maria Sporre and Magnus Becker
    Citation: BMC Pediatrics 2021 21:309
    Content type: Research article Published on:

  6. Less than 2% of overweight children and adolescents in Switzerland can participate in multi-component behaviour changing interventions (BCI), due to costs and lack of time. Stress often hinders positive health...

    Authors: A. Stasinaki, D. Büchter, C.-H. I. Shih, K. Heldt, S. Güsewell, B. Brogle, N. Farpour-Lambert, T. Kowatsch and D. l’Allemand
    Citation: BMC Pediatrics 2021 21:308
    Content type: Research Published on:

  7. Around two and half million neonatal mortality occurred in 2017, especially in developing countries. This study was conducted to determine the determinants of neonatal mortality among newborns admitted in the ...

    Authors: Atnafu Adem, Azmach Dache and Aregahegn Dona
    Citation: BMC Pediatrics 2021 21:307
    Content type: Research Published on:

  8. Perinatal asphyxia is a complicated newborn health problem and applies a high contribution to the increased proportion of newborn mortality. It occurs in newborns due to altered breathing or inadequate inhalat...

    Authors: Samuel Dessu, Zinabu Dawit, Abebe Timerga and Muluken Bafa
    Citation: BMC Pediatrics 2021 21:304
    Content type: Research Published on:

  9. European Society for Clinical Nutrition and Metabolism released the guidelines on pediatric parenteral nutrition in 2018. We aimed to compare the parenteral nutrition (PN) regimen with the current guidelines, ...

    Authors: Nan Wang, Lianlian Cui, Zhen Liu, Yan Wang, Yuhua Zhang, Changsong Shi and Yanbo Cheng
    Citation: BMC Pediatrics 2021 21:303
    Content type: Research Published on:

  10. The current neonatal mortality rate in Nigeria (37/1000) is among the highest in the world and the major causes have consistently been reported as sepsis, perinatal asphyxia and prematurity. However, case-spec...

    Authors: L. I. Audu, A. T. Otuneye, A. B. Mairami, M. Mukhtar-Yola and L. J. Mshelia
    Citation: BMC Pediatrics 2021 21:302
    Content type: Research Published on:

  11. The most common cause of respiratory failure in premature infants is respiratory distress syndrome. Historically, respiratory distress syndrome has been treated by intratracheal surfactant injection followed b...

    Authors: Arash Malakian, Mohammad Reza Aramesh, Mina Agahin and Masoud Dehdashtian
    Citation: BMC Pediatrics 2021 21:301
    Content type: Research article Published on:

  13. Vitamin A deficiency (VAD) and sleep disturbances have been reported in children with autism spectrum disorder (ASD). The influence of vitamin A (VA) levels on sleep regulation and sleep disturbances in ASD ha...

    Authors: Jing Wen, Ting Yang, Jiang Zhu, Min Guo, Xi Lai, Ting Tang, Li Chen, Jie Chen, Ming Xue and Tingyu Li
    Citation: BMC Pediatrics 2021 21:299
    Content type: Research article Published on:

    The Retraction Note to this article has been published in BMC Pediatrics 2021 21:547

  14. The prevalence of diabetes mellitus (DM) during pregnancy and childhood obesity is increasing worldwide. Factors affecting the growth of children with overweight whose mothers had DM are complicated and inconc...

    Authors: Yuan-Der Huang, Yun-Ru Luo, Meng-Chih Lee and Chih-Jung Yeh
    Citation: BMC Pediatrics 2021 21:298
    Content type: Research article Published on:

  15. Infantile malignant osteopetrosis (IMO) is a rare autosomal recessive disease characterized by a higher bone density in bone marrow caused by the dysfunction of bone resorption. Clinically, IMO can be diagnose...

    Authors: Ping Wu, Zhe Cai, Wen-Hui Jiang, Gen Lu, Pei-Qiong Wu, Zhi-Wei Xie, Jun-Zheng Peng, Chen Chen, Jun-Ye Qi, Li-Zhen Xu, Kun-Ling Shen, Hua-Song Zeng and Gen-Quan Yin
    Citation: BMC Pediatrics 2021 21:297
    Content type: Case report Published on:

  16. Newborn screening (NBS) for sickle cell disease incidentally identifies heterozygous carriers of hemoglobinopathy mutations. In Ontario, Canada, these carrier results are not routinely disclosed, presenting an...

    Authors: Sara D. Khangura, Beth K. Potter, Christine Davies, Robin Ducharme, A. Brianne Bota, Steven Hawken, Kumanan Wilson, Maria D. Karaceper, Robert J. Klaassen, Julian Little, Ewurabena Simpson and Pranesh Chakraborty
    Citation: BMC Pediatrics 2021 21:296
    Content type: Research Published on:

  18. Migraine is common in childhood, peaks in adolescents and persists into adulthood in at least 40% of patients. There is need for early interventions to improve the burden of disease and, if possible, reduce ch...

    Authors: Mirjam N. Landgraf, Florian Heinen, Lucia Gerstl, Christine Kainz, Ruth Ruscheweyh, Andreas Straube, Joerg Scheidt, Sabine von Mutius, Viola Obermeier and Ruediger von Kries
    Citation: BMC Pediatrics 2021 21:294
    Content type: Study protocol Published on:

  19. The spondylodysplastic Ehlers-Danlos subtype (OMIM #130070) is a rare connective tissue disorder characterized by a combination of connective tissue symptoms, skeletal features and short stature. It is caused by ...

    Authors: Delia Lorenz, Wolfram Kress, Ann-Kathrin Zaum, Christian P. Speer and Helge Hebestreit
    Citation: BMC Pediatrics 2021 21:293
    Content type: Case report Published on:

  20. Midregional-proadrenomedullin (MR-proADM) is a useful prognostic peptide in severe infectious pathologies in the adult population. However, there are no studies that analyze its utility in febrile urinary trac...

    Authors: Rafael Peñalver Penedo, Marta Rupérez Lucas, Luis Antonio Álvarez-Sala Walther, Alicia Torregrosa Benavent, María Luisa Casas Losada, Luis Bañuelos Andrio, Ana Belén Rebolledo Poves and Mercedes Bueno Campaña
    Citation: BMC Pediatrics 2021 21:292
    Content type: Research article Published on:

  21. Hereditary spherocytosis (HS) is a common inherited red blood cell membrane disorder characterized by an abnormal increase of spherocytes in peripheral blood. SPTB gene mutation is one of the most common causes o...

    Authors: Zhanhui Du, Gang Luo, Kuiliang Wang, Zhen Bing and Silin Pan
    Citation: BMC Pediatrics 2021 21:291
    Content type: Case report Published on:

  22. Diarrheal disease is still one of the most common causes of mortality and morbidity in children under five in developing countries, including Ethiopia. Lack of specific data on the prevalence of acute diarrhea...

    Authors: Tarikuwa Natnael, Mistir Lingerew and Metadel Adane
    Citation: BMC Pediatrics 2021 21:290
    Content type: Research Published on:

  24. The Lebanese population has undergone several conflicts and were the most afflicted by shelling and chaos during the civil war from 1975 to 1990, or even by displacement, bereavement, emigration, family separa...

    Authors: Georges Merhy, Vanessa Azzi, Pascale Salameh, Sahar Obeid and Souheil Hallit
    Citation: BMC Pediatrics 2021 21:288
    Content type: Research Published on:

  25. A predictive model for risk of Mycoplasma pneumoniae (MP)-related hepatitis in MP pneumonia pediatric patients can improve treatment selection and therapeutic effect. However, currently, no predictive model is av...

    Authors: Yuna Bi, Yan Ma, Jinhua Zhuo, Lili Zhang, Liyan Yin, Hongling Sheng, Jie Luan and Tao Li
    Citation: BMC Pediatrics 2021 21:287
    Content type: Research article Published on:

  26. Patent ductus arteriosus (PDA) is a common complication in very preterm infants. It is known that there is an association between PDA and development of bronchopulmonary dysplasia (BPD) or death before the pos...

    Authors: Solomiia Potsiurko, Dmytro Dobryanskyy and Lesya Sekretar
    Citation: BMC Pediatrics 2021 21:286
    Content type: Research Published on:

  27. Children who are high priority candidates for early intervention need to be identified to reduce their risk for experiencing problems in development. Those exposed to multiple risk factors are more likely to e...

    Authors: Jan L. Wallander, Sarah Berry, Polly Atatoa Carr, Elizabeth R. Peterson, Karen E. Waldie, Emma Marks, Stephanie D’Souza and Susan M. B. Morton
    Citation: BMC Pediatrics 2021 21:285
    Content type: Research article Published on:

  28. Acute respiratory infections (ARI) cause considerable morbidity and mortality worldwide, especially in children. Unfortunately, there are limited multi-center data on common viral respiratory infections in sou...

    Authors: Yajie Zhang, Lin Qiao, Jinxiu Yao, Nan Yu, Xiaoping Mu, Shengqi Huang, Bo Hu, Weixuan Li, Feng Qiu, Fangyin Zeng, Cong Chen, Yuqiu Zhou, Bashan Zhang, Tian Cai, Weijia Wang, Xianjin Wu…
    Citation: BMC Pediatrics 2021 21:284
    Content type: Research Published on:

  30. Hereditary cancer susceptibility syndrome (HCSS) contributes to the cancer predisposition at an early age, therefore, identification of HCSS has found to be crucial for surveillance, managing therapeutic inter...

    Authors: Sara Aslam, Shabana and Mehboob Ahmed
    Citation: BMC Pediatrics 2021 21:282
    Content type: Research Published on:

  31. Respiratory Distress Syndrome (RDS) is a common cause of neonatal morbidity and mortality in premature newborns. In this study, we aim to compare the reintubation rate in preterm babies with RDS who were extub...

    Authors: Alaa Masry, Nuha A. M. A. Nimeri, Olfa Koobar, Samer Hammoudeh, Prem Chandra, Einas E. Elmalik, Amr M. Khalil, Nasir Mohammed, Nazla A. M. Mahmoud, Lisa J. Langtree and Mohammad A. A. Bayoumi
    Citation: BMC Pediatrics 2021 21:281
    Content type: Research Published on:

  34. Evidence for periconceptional or prenatal environmental risk factors for the development of congenital diaphragmatic hernia (CDH) is still scarce. Here, in a case-control study we investigated potential enviro...

    Authors: Felicitas Schulz, Ekkehart Jenetzky, Nadine Zwink, Charlotte Bendixen, Florian Kipfmueller, Neysan Rafat, Andreas Heydweiller, Lucas Wessel, Heiko Reutter, Andreas Mueller and Thomas Schaible
    Citation: BMC Pediatrics 2021 21:278
    Content type: Research Published on:

  36. Organ size is influenced by a number of factors. Age, height, weight, and ethnicity are known influencing factors. Pediatric populations have changed over time, puberty beginning earlier resulting in a changin...

    Authors: Stephan Waelti, Tim Fischer, Simon Wildermuth, Sebastian Leschka, Tobias Dietrich, Sabine Guesewell, Pascal Mueller, Michael Ditchfield and Stefan Markart
    Citation: BMC Pediatrics 2021 21:276
    Content type: Research article Published on:

  37. Several factors like altitude, age, sex, pregnancy, socioeconomic status, life style and race influence hematological reference interval (RIs), which are critical to support clinical decisions and to interpret...

    Authors: Ammanuel Angelo, Girma Derbie, Asrat Demtse and Aster Tsegaye
    Citation: BMC Pediatrics 2021 21:275
    Content type: Research Published on:

  38. Sudden unexpected infant death (SUID) continues to be a major contributor to infant mortality in the United States. The objective was to analyze time trends in SUID and their association with immunization cove...

    Authors: Jacqueline Müller-Nordhorn, Konrad Neumann, Thomas Keil, Stefan N. Willich and Sylvia Binting
    Citation: BMC Pediatrics 2021 21:274
    Content type: Research Published on:

  41. Childhood obesity increases the risk of non-alcoholic fatty liver disease marked by elevated alanine aminotransferase (ALT). This study investigated the prevalence of increased ALT in children and adolescents ...

    Authors: Resthie R. Putri, Thomas Casswall and Emilia Hagman
    Citation: BMC Pediatrics 2021 21:271
    Content type: Research Published on:

  42. This study aimed to provide UK data describing the incidence of patent ductus arteriosus (PDA) surgery in the neonatal population, including: pre-ligation management, and outcomes until discharge. We used Brit...

    Authors: A. Warnock, L. Szatkowski, A. Lakshmanan, L. Lee and W. Kelsall
    Citation: BMC Pediatrics 2021 21:270
    Content type: Research Published on:

  44. Genome wide gene expression analysis has revealed hints for independent immunological pathways underlying the pathophysiologies of phlegmonous (PA) and gangrenous appendicitis (GA). Methods of artificial intel...

    Authors: Josephine Reismann, Natalie Kiss and Marc Reismann
    Citation: BMC Pediatrics 2021 21:268
    Content type: Research article Published on:

  45. Multisystem Inflammatory Syndrome in Children (MIS-C) is a severe complication of coronavirus disease 2019 (COVID-19) in children, which is increasingly being reported worldwide. Here we report the first case ...

    Authors: Mohammad Rubayet Hasan, Khaled Al Zubaidi, Karim Diab, Yahia Hejazi, Sharon Bout-Tabaku, Buthaina Al-Adba, Eman Al Maslamani, Mohammad Janahi, Diane Roscoe, Andres Perez Lopez and Patrick Tang
    Citation: BMC Pediatrics 2021 21:267
    Content type: Research Published on:

  46. Newborn morbidity and mortality are forecasted using the Apgar scores. Obstetricians worldwide have used the Apgar score for more than half a century for the assessment of immediate newborn conditions. It is a...

    Authors: Alex Yeshaneh, Andargachew Kassa, Zemenu Yohannes Kassa, Daniel Adane, Yohannes Fikadu, Semahegn Tilahun Wassie, Biresaw Wassihun Alemu, Mesfin Tadese, Solomon Shitu and Haimanot Abebe
    Citation: BMC Pediatrics 2021 21:266
    Content type: Research Published on:

  47. Spontaneous infection of preexisting solitary renal cysts has been documented in adults but is extremely rare in children. To date, no cases of simple renal cysts infected with Streptococcus pneumoniae have been ...

    Authors: Yoji Uejima, Hideki Niimi, Reiko Kato, Mihoko Furuichi, Satoshi Sato, Isao Kitajima, Yutaka Kawano, Tsutomu Oh-Ishi, Hiroshi Kawashima and Eisuke Suganuma
    Citation: BMC Pediatrics 2021 21:265
    Content type: Case report Published on:

  49. Girls with classical congenital adrenal hyperplasia (CAH) are exposed to excess fetal adrenal androgens in-utero, and often born with masculinised genitalia. They are conventionally reared as females, but show...

    Authors: Sumudu Nimali Seneviratne, Umesh Jayarajah, Shamaali Gunawardana, Malik Samarasinghe and Shamya de Silva
    Citation: BMC Pediatrics 2021 21:262
    Content type: Research Published on:

  50. Neonatal hypoxic-ischemic encephalopathy (HIE) affects as many as 100,000 infants each year in China. Therapeutic hypothermia reduces HIE related mortality and long-term neurodevelopmental disabilities. Nation...

    Authors: Zheng Wang, Peng Zhang, Wenhao Zhou, Shiwen Xia, Wei Zhou, Xiaoyu Zhou, Xiuyong Cheng, Yuan Shi, Zhenlang Lin, Dongli Song and Guoqiang Cheng
    Citation: BMC Pediatrics 2021 21:261
    Content type: Research article Published on:
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BMC Pediatrics

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