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  1. Data on childhood disability is essential for planning health, education and other services. However, information is lacking in many low- and middle-income countries, including Niger. This study uses the Key I...

    Authors: Lena Morgon Banks, Jing Liu, Anne Kielland, Ali Bako Tahirou, Abdoul Karim Seydou Harouna, Islay Mactaggart, Ragnhild Dybdahl, Dan Firoun Mounkaila and Arne Grønningsæter
    Citation: BMC Pediatrics 2022 22:170
  2. This study aims to explore and elucidate parents’ experience of newborn screening [NBS], with the overarching goal of identifying desiderata for the development of informatics-based educational and health mana...

    Authors: Mike Conway, Truc Thuy Vuong, Kim Hart, Andreas Rohrwasser and Karen Eilbeck
    Citation: BMC Pediatrics 2022 22:167
  3. Respiratory virus infection is common in early childhood, and children may be symptomatic or symptom-free. Little is known regarding the association between symptomatic/asymptomatic infection and particular cl...

    Authors: Elizabeth Powell, Edward Sumner, Alex G. Shaw, Ronan Calvez, Colin G. Fink and J. Simon Kroll
    Citation: BMC Pediatrics 2022 22:166
  4. Birth asphyxia is the major public health problem in the world. It is estimated that around 23% of all newborn deaths are caused by birth asphyxia worldwide. Birth asphyxia is the top three causes of newborn d...

    Authors: Sisay Shine Tegegnework, Yeshfanos Tekola Gebre, Sindew Mahmud Ahmed and Abrham Shitaw Tewachew
    Citation: BMC Pediatrics 2022 22:165
  5. Immune thrombocytopenia (ITP) is the most common etiology of acquired thrombocytopenia diseases in children. ITP is characterized by the immune-mediated decreased formation and excessive destruction of platele...

    Authors: Qi Wang, Jia Wei, Xi Jia, Xiao Feng, Zhenghua Ji, Xueqiang Ji and Xuejun Shao
    Citation: BMC Pediatrics 2022 22:164
  6. Colic and sleep problems are common among infants, constitute challenges and distress for parents, and are often reasons for seeking help from health professionals. The literature debates whether infant colic ...

    Authors: Sølvi Helseth, Nina Misvær, Milada Småstuen, Randi Andenæs and Lisbeth Valla
    Citation: BMC Pediatrics 2022 22:163
  7. To explore and analyze the causes and related influencing factors of pediatric fractures, and provide theoretical basis for reducing the incidence and adverse effects of pediatric fractures.

    Authors: Xin Qiu, Hansheng Deng, Qiru Su, Shuaidan Zeng, Shuai Han, Shicheng Li, Zhiwen Cui, Tianfeng Zhu, Gen Tang, Zhu Xiong and Shengping Tang
    Citation: BMC Pediatrics 2022 22:161
  8. This study aimed to assess the quality of global guidelines or consensus statements for newborn and childhood hearing screening, as well as to compare various guidelines between other countries and China.

    Authors: Cheng Wen, Xuelei Zhao, Yue Li, Yiding Yu, Xiaohua Cheng, Xiaohong Li, Kui Deng, Xuelian Yuan and Lihui Huang
    Citation: BMC Pediatrics 2022 22:160
  9. Early support for children with developmental disabilities is crucial but frequently unavailable in low-resource settings. We conducted a mixed-methods evaluation to assess the feasibility, acceptability, and ...

    Authors: S. Sadoo, R. Nalugya, R. Lassman, M. Kohli-Lynch, G. Chariot, H. G. Davies, E. Katuutu, M. Clee, J. Seeley, E. L. Webb, R. Mutoni Vedastine, F. Beckerlegge and C. J. Tann
    Citation: BMC Pediatrics 2022 22:158
  10. Outpatient therapeutic program (OTP) brings the services for the management of Severe Acute Malnutrition (SAM) closer to the community by making services available at decentralized treatment points within the ...

    Authors: Smegnew Gichew Wondie, Beakal Zinab, Getu Gizaw and Meseret Tamrat
    Citation: BMC Pediatrics 2022 22:157
  11. The amplitude-integrated EEG (aEEG) is a widely used monitoring tool in neonatology / pediatric intensive care. It takes into account the amplitudes, but not the frequency composition, of the EEG. Advantages o...

    Authors: Barbara Schultz, Michael Schultz, Martin Boehne and Nils Dennhardt
    Citation: BMC Pediatrics 2022 22:156
  12. The Supplemental Nutrition Assistance Program (SNAP) has well-established positive impacts on child health outcomes, including increased birth weight and decreased likelihood of underweight status. Studies in ...

    Authors: Stephen Rogers, Arvin Garg, Yorghos Tripodis, Annelise Brochier, Emily Messmer, Mikayla Gordon Wexler and Alon Peltz
    Citation: BMC Pediatrics 2022 22:155
  13. Infectious diseases like the common cold, otitis media, or gastroenteritis frequently occur in childhood. In addition to prescription drugs, parents often use supplementary over-the-counter (OTC) products reco...

    Authors: Matthias Gerlitz, Peter Voitl, Julian J. M. Voitl and Susanne C. Diesner-Treiber
    Citation: BMC Pediatrics 2022 22:154
  14. Preterm related complications are the single largest direct cause of neonatal deaths throughout the world, responsible for 35% of the world’s neonatal death (1.1 million deaths/year). In Ethiopia preterm relat...

    Authors: Dires Birhanu, Bereket Gebremichael, Tewodros Tesfaye, Misrak Tadesse, Fekadeselassie Belege, Yohannes Godie, Markos Wodaje and Eyerusalem Tamiru
    Citation: BMC Pediatrics 2022 22:153
  15. Guillain-Barré syndrome is the most common cause of flaccid paralysis, with multiple known clinical variants. Autonomic dysfunction, although frequently reported in the clinical course, is often overlooked in ...

    Authors: C. Bonilla, M. I. Alvarez-Olmos, C. Uribe and J. Fernández-Sarmiento
    Citation: BMC Pediatrics 2022 22:152
  16. Severe fatal human adenoviral (HAdV) pneumonia is associated with significant mortality and no effective drug is available for clinical therapy. We evaluated the association and safety of high titer neutralizi...

    Authors: Hongyan Peng, Feiyan Chen, Yunlong Zuo, Bolun Huang, Yiyu Yang and Run Dang
    Citation: BMC Pediatrics 2022 22:151
  17. The “Assessment of Motor Repertoire—3 to 5 Months”, which is a part of Prechtl's General Movements Assessment (GMA), has been gradually applied to infants with genetic metabolic disorders. However, there have ...

    Authors: Jun Wang, Xiushu Shen, Hong Yang, Wei Shi, Xiaoyun Zhu, Herong Gao, Huanhuan Yin, Fanzhe Meng and Yun Wu
    Citation: BMC Pediatrics 2022 22:150
  18. Acute lymphoblastic leukemia (ALL) is the most common type of cancer in the age range of under 15 years old and accounts for 25–30% of all childhood cancers. Although conventional chemotherapy regimens are use...

    Authors: Omid Reza Zekavat, Elham Nikpendar, Sezaneh Haghpanah, Negin Shokrgozar, Seyed Javad Dehghani and Nargess Arandi
    Citation: BMC Pediatrics 2022 22:149
  19. Since Ethiopia has been implemented the Community-Led Total Sanitation and Hygiene (CLTSH) approach to control incidence of diarrhea, few studies have compared the prevalence of diarrhea and associated factors...

    Authors: Gezahegn Mernie, Helmut Kloos and Metadel Adane
    Citation: BMC Pediatrics 2022 22:148
  20. The objective of this study was to assess if children aged 0–23 months in a conflict-affected state of South Sudan were on track with their immunization schedule and to identify predisposing factors that affec...

    Authors: Israel Oluwaseyidayo Idris, Janet Tapkigen, Germaine Kabutaulaka, Gabriel Omoniyi Ayeni, Francis Ifeanyi Ayomoh and Justin Geno Obwoya
    Citation: BMC Pediatrics 2022 22:147
  21. The Peripheral Arterial Tonometry (PAT) technique measured by Endo-PAT™, is recently introduced for peripheral vascular assessment in youth, primarily benefits from its easy and non-invasive operation. However...

    Authors: Wennan He, Yi Zhang, Xuesong Li, Kai Mu, Yalan Dou, Ying Ye, Fang Liu and Weili Yan
    Citation: BMC Pediatrics 2022 22:146
  22. Hydrocephalus (HCP) is a common disorder of cerebral spinal fluid (CSF) physiology resulting in abnormal expansion of the cerebral ventricles. Infants commonly present with progressive macrocephaly whereas chi...

    Authors: Blein Mulugeta, Girma Seyoum, Abebe Mekonnen and Elbet Ketema
    Citation: BMC Pediatrics 2022 22:145
  23. Research and development of pediatric drug faces many difficulties and pediatric clinical trials remain a challenge. Since 2011, a series of measures have been taken to encourage research, development of drugs...

    Authors: Lin Song, Yuntao Jia, Sujuan Ran, Bin Li, Jin Xu, Bennian Huo, Nange Yin, Maolin Ai and Yao Liu
    Citation: BMC Pediatrics 2022 22:144
  24. During puberty, changes in body composition due to sex hormones are associated with lung mechanics. However, little is known about the mediation effect of sex differences in body composition during puberty wit...

    Authors: Ju Hee Kim, Jin Ah Kim, Eun Kyo Ha, Hye Mi Jee, Seung Won Lee, Mo Kyung Jung, Sanghoo Lee, Yoon Ho Shin, Eun-Gyong Yoo and Man Yong Han
    Citation: BMC Pediatrics 2022 22:143
  25. Noonan syndrome (NS) is a relatively rare inherited disease. Typical clinical presentation is important for the diagnosis of NS. But the initial presentation of NS could be significant variant individually whi...

    Authors: Xiujun Tang, Zheng Chen, Xiaoxia Shen, Tian Xie, Xiaohong Wang, Taixiang Liu and Xiaolu Ma
    Citation: BMC Pediatrics 2022 22:142
  26. The relationship between physical activity and health care costs among adolescents is not yet clear in the literature.

    Authors: Wésley Torres, Lucas Gabriel de Moraes Chagas, Rômulo Araújo Fernandes, Monique Yndawe Castanho Araujo, Jacqueline Bexiga Urban, Santiago Maillane-Vanegas, Bruna Camilo Turi-Lynch, Jamile Sanches Codogno and Nana Kwame Anokye
    Citation: BMC Pediatrics 2022 22:141
  27. Bacterial infection (BI), both community-acquired (CA-BI) and hospital-acquired (HAI), might present as a severe complication in patients with bronchiolitis. This study aimed to describe BI in children with se...

    Authors: Carmina Guitart, Carme Alejandre, Sara Bobillo-Perez, Monica Girona-Alarcon, Anna Sole-Ribalta, Francisco Jose Cambra, Monica Balaguer and Iolanda Jordan
    Citation: BMC Pediatrics 2022 22:140
  28. Congenital mesoblastic nephromas mainly present as asymptomatic abdominal masses, but some present hematuria, hypertension or hypercalcemia. Neonatal dyspnea in an early-birth neonate due to rapid tumor growth...

    Authors: Hirotaka Kato, Yasuyuki Mitani, Taro Goda and Hiroki Yamaue
    Citation: BMC Pediatrics 2022 22:139
  29. To assess the outcome of extracorporeal membrane oxygenation (ECMO) for severe adenovirus (Adv) pneumonia with refractory hypoxic respiratory failure (RHRF) in paediatric patients.

    Authors: Yun Cui, Jingyi Shi, Yiping Zhou, Jiaying Dou, Xi Xiong, Ting Sun, Yijun Shan, Tingting Xu, Ye Lu and Yucai Zhang
    Citation: BMC Pediatrics 2022 22:138
  30. Neonatal acute kidney injury (AKI) has been associated with unfavorable outcomes, including increased mortality. We aimed to describe the clinical course and outcomes during the first 7 days after diagnosis in...

    Authors: O. C. Pantoja-Gómez, S. Realpe, Ginna Cabra-Bautista, J. M. Restrepo, O. L. Prado, A. M. Velasco, G. E. Martínez, S. Leal, A. Vallejo and Jose Andrés Calvache
    Citation: BMC Pediatrics 2022 22:136
  31. Strokes in the paediatric age group have their own epidemiology and aetiology and are frequently misdiagnosed. As in the adult population, they present some risk factors that must be identified. Cerebral arter...

    Authors: Víctor González-Maestro, Einés Monteagudo-Vilavedra, Jorge Rodríguez-Antuña, Marta Lendoiro-Fuentes, María Soledad Brage Gómez and Elena Maside Miño
    Citation: BMC Pediatrics 2022 22:135
  32. The purpose of this study was to evaluate the utility of endoscopic retrograde cholangiopancreatography (ERCP) in pediatric patients with pancreaticobiliary diseases.

    Authors: Satoshi Makita, Hizuru Amano, Hiroki Kawashima, Akinari Hinoki, Chiyoe Shirota, Takahisa Tainaka, Wataru Sumida, Kazuki Yokota, Masamune Okamoto, Aitaro Takimoto, Akihiro Yasui, Yoichi Nakagawa and Hiroo Uchida
    Citation: BMC Pediatrics 2022 22:134
  33. Functional exercises is very essential to the recovery of patients with fracture. We aimed to evaluate the compliance of functional exercises in school-age children with limb fracture, to provide evidence to t...

    Authors: Hui Liu, Yun Wang, Mengya Li, Dan Chen and Yuping Tang
    Citation: BMC Pediatrics 2022 22:133
  34. Kawasaki disease (KD) is an acute, febrile, systemic vasculitis of unknown etiology that primarily affects the coronary arteries and generally occurs at around 1 year of age. Although the diagnosis of KD is ge...

    Authors: Yoshiki Kawamura, Hiroki Miura, Kazuyoshi Saito, Takayuki Kanno, Tadafumi Yokoyama, Yuta Aizawa and Tetsushi Yoshikawa
    Citation: BMC Pediatrics 2022 22:132
  35. Homozygous familial hypercholesterolemia (hoFH) is a rare genetic disorder leading to extremely increased LDL-cholesterol (LDL-C), resulting in high cardiovascular risk in early childhood. Lipid apheresis (LA)...

    Authors: Julia Lischka, Klaus Arbeiter, Charlotte de Gier, Andrea Willfort-Ehringer, Nina-Katharina Walleczek, Renata Gellai, Michael Boehm, Albert Wiegman and Susanne Greber-Platzer
    Citation: BMC Pediatrics 2022 22:131
  36. Patient-level predictors of enrollment in pediatric biorepositories are poorly described. Especially in pandemic settings, understanding who is likely to enroll in a biorepository is critical to interpreting a...

    Authors: Anne M. Neilan, Anisha Tyagi, Yao Tong, Eva J. Farkas, Madeleine D. Burns, Allison Fialkowski, Grace Park, Margot Hardcastle, Elizabeth Gootkind, Ingrid V. Bassett, Fatma M. Shebl and Lael M. Yonker
    Citation: BMC Pediatrics 2022 22:130
  37. Maternal dietary intake during pregnancy plays an important role in fetal development and birth outcomes. The aim of the present study was to determine maternal dietary diversity and Nutritional adequacy in re...

    Authors: Tahereh Karimi, Hassan Eini-Zinab, Arezoo Rezazadeh and Zeinab Moslemi
    Citation: BMC Pediatrics 2022 22:129
  38. Early essential newborn care (EENC) was introduced to medical practice in China in 2016, but the number of medical institutions that have put EENC into practice remains low due to insufficient clinical evidenc...

    Authors: Chuanya Huang, Lei Hu, Jingjing He and Biru Luo
    Citation: BMC Pediatrics 2022 22:127
  39. In this case report, we described the past history, clinical manifestations, genetic characteristics and cognitive evaluation of a boy with congenital insensitivity to pain with anhidrosis (CIPA) who developed...

    Authors: Mi Zhang, Xueqin Cao, Ningbo Li, Guangyou Duan and Xianwei Zhang
    Citation: BMC Pediatrics 2022 22:126
  40. Early infantile epileptic encephalopathy is a severe form of epilepsy that is genetically extremely heterogeneous and characterized by seizures or spasms at the beginning of infancy. Homozygous or compound het...

    Authors: Sepideh Gholami Yarahmadi and Saeid Morovvati
    Citation: BMC Pediatrics 2022 22:125
  41. Acute respiratory tract infection (ARI) is one of the leading causes of illness and mortality in children under the age of five worldwide. Pneumonia, which is caused by a respiratory tract infection, kills abo...

    Authors: Amanuel Merera, Tilahun Asena and Mebratu Senbeta
    Citation: BMC Pediatrics 2022 22:123
  42. Although blood lead levels (BLLs) in children are gradually decreasing, low-concentration lead exposure can still exert adverse effects. We studied the factors that affect BLLs in children in Shenyang, China.

    Authors: Xiao-Jun Cheng, Guang-Bo Li, Shuang-Shuang Zhang, Ying Liu, Yi-Chen Dong and Xue-Ning-Li
    Citation: BMC Pediatrics 2022 22:122
  43. Within Europe, the Netherlands has one of the lowest antibiotic consumption rates. We aimed to gain insight into attitudes of Dutch physicians and parents towards information provided during discharge conversa...

    Authors: Daphne Peeters, Lars M. A. van Scheppingen, Gertjan J. A. Driessen and Lilly M. Verhagen
    Citation: BMC Pediatrics 2022 22:121
  44. Bottle feeding is associated with diarrheal disease morbidity and mortality and risk of pyloric stenosis, especially in developing countries. Even though, World Health Organization (WHO) recommended avoiding b...

    Authors: Daniel Gashaneh Belay, Mihret Getnet, Yonas Akalu, Mengistie Diress, Yibeltal Yismaw Gela, Amare Belete Getahun, Desalegn Anmut Bitew, Bewuketu Terefe and Yitayeh Belsti
    Citation: BMC Pediatrics 2022 22:120
  45. Coats plus syndrome, cerebroretinal microangiopathy with calcifications and cysts, is a rare disease with autosomal recessive pattern occurring due to a mutation in CTC1, encoding conserved telomere maintenanc...

    Authors: Selcen Bozkurt, Ayse Merve Usta, Nafiye Urganci, Nida Gulderen Kalay, Gulsen Kose and Evrim Ozmen
    Citation: BMC Pediatrics 2022 22:119

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