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Table 3 The relationship between perinatal factors and incidence of CRP ≥ 8 mg/L in different models

From: Factors influencing C-reactive protein status on admission in neonates after birth

 

Model 1

 

Model 2

OR (95%CI)

P-value

OR (95%CI)

P-value

GA

1.16 (1.04, 1.30)

0.006

 

1.13 (1.00, 1.28)

0.042

PROM

     

 No

1.0

  

1.0

 

 Yes,<18 h

1.28 (0.67, 2.44)

0.448

 

1.21 (0.62, 2.38)

0.578

 Yes,≥18 h

2.75 (1.66, 4.55)

< 0.001

 

2.39 (1.35, 4.23)

0.003

Prenatal dexamethasone use

     

 No

1.0

  

1.0

 

 Yes

1.56(0.83,2.94)

0.170

 

1.42(0.70,2.89)

0.328

Maternal autoimmune diseases

     

 No

1.0

  

1.0

 

 Yes

4.03 (1.70, 9.52)

0.002

 

5.30 (2.15, 13.07)

<0.001

Delivery mode

     

 Vaginal delivery

1.0

  

1.0

 

 Operative vaginal delivery

1.10 (0.34, 3.48)

0.877

 

1.29 (0.40, 4.22)

0.672

 Cesarean delivery

0.37 (0.25, 0.54)

< 0.001

 

0.40 (0.26, 0.60)

<0.001

MAS

     

 No

1.0

  

1.0

 

 Yes

2.59(0.84,8.03)

0.099

 

2.89(0.90,9.26)

0.073

  1. Result variable: CRP ≥ 8 mg/L
  2. Exposure variable: GA, PROM, prenatal dexamethasone use, maternal autoimmune diseases, delivery mode, MAS.
  3. Model 1 in GA adjusted for: sex, BW.
  4. Model 2 in GA adjusted for: sex, BW, maternal fever, placenta previa, antenatal antibiotic use, PROM, pregnancy hypertension, gestational diabetes, ICP, MAS, prenatal dexamethasone use, maternal autoimmune diseases, delivery mode
  5. Model 1 in PROM adjusted for: sex, gestational age, BW.
  6. Model 2 in PROM adjusted for: sex, GA, BW, maternal fever, placenta previa, delivery mode, antenatal antibiotic use, pregnancy hypertension, gestational diabetes, ICP, MAS, prenatal dexamethasone use, maternal autoimmune diseases
  7. Model 1 in prenatal dexamethasone use adjusted for: sex, gestational age, BW.
  8. Model 2 in prenatal dexamethasone use adjusted for: sex, GA, BW, maternal fever, placenta previa, antenatal antibiotic use, PROM, pregnancy hypertension, gestational diabetes, ICP, MAS, maternal autoimmune diseases, delivery mode
  9. Model 1 in maternal autoimmune diseases adjusted for: sex, gestational age, BW.
  10. Model 2 in maternal autoimmune diseases adjusted for: sex, GA, BW, maternal fever, placenta previa, antenatal antibiotic use, PROM, pregnancy hypertension, gestational diabetes, ICP, MAS, prenatal dexamethasone use, delivery mode
  11. Model 1 in delivery mode adjusted for: sex, gestational age, birth weight
  12. Model 2 in delivery mode adjusted for: sex, GA, BW, maternal fever, placenta previa, antenatal antibiotic use, PROM, pregnancy hypertension, gestational diabetes, ICP, MAS, prenatal dexamethasone use, maternal autoimmune diseases
  13. Model 1 in MAS adjusted for: sex, gestational age, birth weight
  14. Model 2 in MAS adjusted for: sex, GA, BW, maternal fever, placenta previa, antenatal antibiotic use, PROM, pregnancy hypertension, gestational diabetes, ICP, prenatal dexamethasone use, maternal autoimmune diseases, delivery mode
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BMC Pediatrics

ISSN: 1471-2431

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