An explorative study on proteomic analyses related to inflammation and pain in children with juvenile idiopathic arthritis

Table 4 Correlations between normal protein expression (NPX)-levels in 25 of 92 inflammatory proteins versus JADAS 27 scores (0–57) in 50 children (missing data in one child) with juvenile idiopathic arthritis (JIA) in an active disease state adjusted for age and gender

Protein	Correlation coefficients	P-value*	Adjusted p-value**
S100A12	0.53	< 0.001	0.005
MMP-1	0.53	< 0.001	0.005
IL6	0.52	< 0.001	0.005
TNFSF14	0.48	< 0.001	0.015
LIF	0.44	0.002	0.029
MCP3	0.41	0.004	0.053
CX3CL1	-0.39	0.006	0.075
IL8	0.38	0.007	0.086
SIRT-2	0.37	0.009	0.089
VEGFA	0.37	0.010	0.089
CSF1	0.36	0.012	0.097
IL18R1	0.35	0.014	0.110
PD-L1	0.34	0.017	0.121
CXCL11	0.34	0.018	0.121
CCL19	0.33	0.022	0.128
IL33	0.33	0.022	0.128
TGFβ	0.32	0.025	0.131
CDCP1	0.32	0.027	0.131
DNER	-0.32	0.027	0.131
ST1A1	0.31	0.032	0.145
CASP8	0.30	0.035	0.154
FGF21	0.30	0.037	0.155
SCF	-0.30	0.040	0.159
CXCL1	0.30	0.042	0.160
CCL3	0.29	0.048	0.177

ISSN: 1471-2431