Association between early fluid overload and mortality in critically-ill mechanically ventilated children: a single-center retrospective cohort study

Table 4 Multivariate log regression analysis for association of early FO with in-hospital mortality

Outcome measure	β	OR	95% C.I.	P-value
No. of vasoactive drugs	0.413	1.511	1.107–2.063	0.009
Time of MV	−0.080	0.923	0.428–1.991	0.838
Duration of MV	0.045	1.046	1.017–1.075	0.001
Receipt of CRRT	−0.329	0.720	0.316–1.638	0.433
Diagnosis of MODS	1.724	5.609	2.570–12.239	<0.001
Surgery	−0.869	0.419	0.190–0.924	0.031
Early FO	0.030	1.031	0.995–1.067	0.090
PRISM-III score	0.016	1.016	0.964–1.071	0.561

Hosmer–Lemeshow P = 0.805; predicted percentage 80.3%. OR: odds ratio; 95% CI: 95% confidence interval; MV: mechanical ventilation; MODS: multiple organ dysfunction syndrome; CRRT: continuous renal replacement therapy; PRISM-III: third-generation admission pediatric risk of mortality score; FO: fluid overload. No.: number

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