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Table 3 Comparison of survivors with non-survivors

From: Association between early fluid overload and mortality in critically-ill mechanically ventilated children: a single-center retrospective cohort study

Variable Survivors Non-survivors P-value
Number, N (%) 228 (73.8%) 81 (26.2%)  
Age (months, m), median (IQR) 11.5 (4.4–48.6) 16.4 (5.1–56.6) 0.264
Weight (kg) 8.6 (5.8–15.0) 10.0 (6.0–15.0) 0.440
Gender, N (%)    0.692
Male 136 (59.6%) 51 (63.0%)  
Female 92 (40.4%) 30 (37.0%)  
Underlying disease, N (%) 155 (68.0%) 59 (72.8%) 0.484
Reason for PICU admission, N (%)    <0.001
Medical, N (%) 135 (59.2%) 67 (82.7%)  
Surgical, N (%) 93 (40.8%) 14 (17.3%)  
Receipt of CRRT, N (%) 33 (14.5%) 26 (32.1%) 0.001
Receipt of vasoactive drugs, N (%) 96 (42.1%) 62 (76.5%) <0.001
No. of vasoactive drugs, median (IQR) 0.0 (0.0–1.0) 2.0 (1.0–3.0) <0.001
Diagnosis of MODS, N (%) 37 (16.2%) 54 (66.7%) <0.001
PRISM-III score, median (IQR) 5.0 (2.3–9.0) 6.0 (2.0–12.5) 0.098
Time from hospital admission to PICU (days), median (IQR) 0.0 (0.0–5.0) 0.0 (0.0–3.5) 0.153
LOS in PICU (days), median (IQR) 18.0 (11.0–27.8) 16.0 (6.5–28.0) 0.088
LOS in hospital (days), median (IQR) 30.0 (20.0–46.8) 17.0 (8.0–31.5) <0.001
Time of MV, median (IQR) 1.0 (1.0–1.0) 1.0 (1.0–1.0) 0.064
Duration of MV (days), median (IQR) 6.0 (4.0–11.0) 9.0 (5.0–22.0) 0.001
Duration of first MV (days), median (IQR) 6.0 (4.0–10.0) 9.0 (5.0–19.0) 0.001
Proportion of patients receiving MV for more than 7 days, N (%) 77 (33.8%) 47 (58.0%) <0.001
Early FO, median (IQR) 8.1 (1.5–13.9) 7.6 (1.7–16.1) 0.992
Percentage of %FO > 10%, N (%) 98 (43.0%) 33 (40.7%) 0.794
Percentage of %FO > 20%, N (%) 15 (6.6%) 12 (14.8%) 0.037
  1. LOS: length of stay; MV: mechanical ventilation; MODS: multiple organ dysfunction syndrome; CRRT: continuous renal replacement therapy; PRISM-III: third-generation admission pediatric risk of mortality score; PICU: pediatric intensive care unit; FO: fluid overload. No.: number. Continuous variables: P-values obtained by Mann–Whitney U-test; categorical variables: P-values obtained by Pearson chi-square test