Table 2 Comparison of all patients by %FO group

Number, N (%)

53 (17.2%)

125 (40.5%)

104 (33.6%)

27 (8.7%)

Age (months, m), median (IQR)

42.4 (14.9–88.3)

18.5 (4.2–60.4)^a,c

7.5 (4.4–19.9)^a

5.8 (3.5–14.8)^a

<0.001

Weight (kg)

15.0 (9.5–25.0)

11.0 (6.6–19.5)

7.0 (5.4–11.0)^a,b

5.8 (4.9–8.2)^a,b

<0.001

Gender, N (%)

0.747

Male

29 (54.7%)

77 (61.6%)

63 (60.6%)

18 (66.7%)

Female

24 (45.3%)

48 (39.4%)

41 (39.4%)

9 (33.3%)

Underlying disease, N (%)

26 (49.1%)

81 (64.8%)

84 (80.8%)^a,b

23 (85.2%)^a,b

<0.001

Reason for PICU admission, N (%)

0.030

Medical, N (%)

39 (73.6%)

85 (68.0%)

57 (54.8%)^a,b,d

21 (77.8%)

Surgical, N (%)

14 (26.4%)

40 (32.0%)

47 (45.2%)^a,b,d

6 (22.2%)

Receipt of CRRT, N (%)

22 (41.5%)

25 (20.0%)^a

7 (6.7%)^a,b

5 (18.5%)^a

<0.001

Receipt of vasoactive drugs, N (%)

38 (71.7%)

62 (49.6%)^a

41 (39.4%)^a,d

17 (63.0%)

0.001

No. of vasoactive drugs, median (IQR)

2.0 (0.0–3.0)^b,c

1.0 (0.0–2.0)

0.0 (0.0-1.0)

1.0 (0.0–2.0)

<0.001

Diagnosis of MODS, N (%)

28 (52.8%)^b,c

35 (28.0%)

19 (18.3%)

9 (33.3%)

0.001

PRISM-III scores, median (IQR)

8.0 (5.5–12.5)^b,c

4.0 (2.5–8.0)

4.0 (1.0–8.0)

5.0 (2.0–10.0)

0.001

In-hospital mortality, N (%)

17 (32.1%)

31 (24.8%)

21 (20.2%)

12 (44.4%)

0.053

Time from hospital admission to PICU (days), median (IQR)

0.0 (0.0–5.0)

0.0 (0.0–4.5)

1.0 (0.0–5.0)

0.0 (0.0–4.0)

0.356

LOS in PICU (days), median (IQR)

16.0 (9.0–22.0)

16.0 (9.0–27.0)

18.5 (10.0–31.0)

21.0 (9.0–32.0)

0.240

LOS in hospital (days), median (IQR)

27.0 (18.5–42.0)

25.0 (16.0–42.0)

30.0 (18.0–46.8)

27.0 (15.0–44.0)

0.240

Time of MV, median (IQR)

1 (1–1)

1 (1–1)

1 (1–1)

1 (1–1)

0.780

Duration of MV (days), median (IQR)

5.0 (4.0–14.0)

6.0 (4.0–11.0)

7.0 (4.0–13.8)

7.0 (5.0–14.0)

0.733

Duration of first MV (days), median (IQR)

5.0 (4.0–13.0)

6.0 (4.0–10.0)

7.0 (4.0–12.0)

7.0 (5.0–14.0)

0.625

Proportion of patients receiving MV for more than 7 days, N (%)

20 (37.7%)

46 (36.8%)

47 (45.2%)

11 (10.8%)

0.616

Early FO, median (IQR)

−3.7 (−6.9 to − 1.2)

5.8 (3.0–7.7)

14.2 (12.0–16.9)

23.1 (21.0–24.3)