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Table 2 Decision to refer for surgery based on gestational age at birth, with P values

From: Surgical management of patent ductus arteriosus in pre-term infants - a british paediatric surveillance study

Reason for decision to refer for surgery

Number reporting reason for decision to refer for surgery by gestational age at birth (n, %)

Chi2 p-value for difference between groups

Extremely preterm (n = 231)

Very preterm (n = 25)

Moderately preterm (n = 7)

Inability to wean respiratory support

199 (86.2)

17 (68.0)

4 (57.1)

0.010

Haemodynamically Significant

203 (87.9)

18 (72.0)

6 (85.7)

0.090

Cardiovascular instability

73 (31.6)

6 (24.0)

2 (28.6)

0.730

Poor growth

48 (20.8)

11 (44.0)

5 (71.4)

< 0.001

Contra-indication of medical therapy

44 (19.1)

3 (12.0)

0 (0)

0.312

Othera

31 (13.4)

3 (12.0)

3 (42.9)

0.083

  1. a Other reasons (n = 37) included: Unable to complete medical treatment (n = 12), NEC (n = 8), PH (n = 4), feeding difficulty (n = 2), duct thought not to be related to prematurity (n = 1), evolving aortic stenosis (n = 1), RSV negative bronchiolitis (n = 1), pulmonary hypoplasia (n = 1), congestive cardiac failure (n = 1), thrombus in aorta (n = 1), chromosome disorder (mosaic trisomy 14) (n = 1). 4 questionnaires specified “other” but no further explanation was documented