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Table 3 Asymptomatic newborns with cardiac murmurs and congenital heart disease diagnosed with echocardiogram

From: Congenital heart disease diagnosed with echocardiogram in newborns with asymptomatic cardiac murmurs: a systematic review

Sources

Number of newborns

during the study period

Number of newborns with murmurs (%)

Number of newborns with murmurs with CHD (%)

Ainsworth et al. [28]

7204

46 (0.6)

25 (54.3)

Rein et al. [29]

20,323

170 (0.8)

110 (64.7)

Azhar et al. [24]

–

75

55 (73.3)

Innocent, 10

7 (70.0)

Possibly pathological, 9

5 (55.6)

Pathological, 56

43 (76.8)

Mackie et al. [30]

–

201

113 (56.2)

Gokmen et al. [25]

618

53 (8.6)

19 (35.8)

Innocent, 41

11 (26.8)

Pathological, 12

8 (66.7)

Mirzarahimi et al. [31]

2928

91 (3.1)

32 (35.2)

Singh et al. [32]

21,957

205 (0.9)

152 (74.1)

Al-Ammouri et al. [33]

22,215

309 (1.4)

68 (22.0)

Minocha et al. [26]

25,128

422 (1.7)

11 (2.6)

Benign, 318

2 (0.6)

Pathologic, 104

9 (8.7)

Fenster et al. [34]

26,573

354 (1.3)

188 (53.1)

  1. Abbreviations: CHD, congenital heart disease