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Table 3 Asymptomatic newborns with cardiac murmurs and congenital heart disease diagnosed with echocardiogram

From: Congenital heart disease diagnosed with echocardiogram in newborns with asymptomatic cardiac murmurs: a systematic review

Sources Number of newborns
during the study period
Number of newborns with murmurs (%) Number of newborns with murmurs with CHD (%)
Ainsworth et al. [28] 7204 46 (0.6) 25 (54.3)
Rein et al. [29] 20,323 170 (0.8) 110 (64.7)
Azhar et al. [24] 75 55 (73.3)
Innocent, 10 7 (70.0)
Possibly pathological, 9 5 (55.6)
Pathological, 56 43 (76.8)
Mackie et al. [30] 201 113 (56.2)
Gokmen et al. [25] 618 53 (8.6) 19 (35.8)
Innocent, 41 11 (26.8)
Pathological, 12 8 (66.7)
Mirzarahimi et al. [31] 2928 91 (3.1) 32 (35.2)
Singh et al. [32] 21,957 205 (0.9) 152 (74.1)
Al-Ammouri et al. [33] 22,215 309 (1.4) 68 (22.0)
Minocha et al. [26] 25,128 422 (1.7) 11 (2.6)
Benign, 318 2 (0.6)
Pathologic, 104 9 (8.7)
Fenster et al. [34] 26,573 354 (1.3) 188 (53.1)
  1. Abbreviations: CHD, congenital heart disease