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  1. Available evidence indicates that early intervention programs, such as the Early Start Denver Model (ESDM), can positively affect key outcomes for children with Autism Spectrum Disorder (ASD). However, program...

    Authors: Valsamma Eapen, Rudi Črnčec and Amelia Walter
    Citation: BMC Pediatrics 2013 13:3
  2. Hypertensive crisis in children is a relatively rare condition presenting with elevated blood pressure (BP) and related symptoms, and it is potentially life-threatening. The aim of this study was to survey chi...

    Authors: Wen-Chieh Yang, Lu-Lu Zhao, Chun-Yu Chen, Yung-Kang Wu, Yu-Jun Chang and Han-Ping Wu
    Citation: BMC Pediatrics 2012 12:200
  3. Estimated 17,000 neonates (≤ 28 days of age) die in Vietnam annually, corresponding to more than half of the child mortality burden. However, current knowledge about these neonates is limited. Prematurity, asp...

    Authors: Alexandra Y Kruse, Binh TT Ho, Cam N Phuong, Lone G Stensballe, Gorm Greisen and Freddy K Pedersen
    Citation: BMC Pediatrics 2012 12:199
  4. While survival rates of extremely preterm infants have improved over the last decades, the incidence of neurodevelopmental disability (ND) in survivors remains high. Representative current data on the severity...

    Authors: Luregn J Schlapbach, Mark Adams, Elena Proietti, Maude Aebischer, Sebastian Grunt, Cristina Borradori-Tolsa, Myriam Bickle-Graz, Hans Ulrich Bucher, Beatrice Latal and Giancarlo Natalucci
    Citation: BMC Pediatrics 2012 12:198
  5. Quality hospital care is important in ensuring that the needs of severely ill children are met to avert child mortality. However, the quality of hospital care for children in developing countries has often bee...

    Authors: Dewan ME Hoque, Muntasirur Rahman, Sk Masum Billah, Michael Savic, AQM Rezaul Karim, Enayet K Chowdhury, Altaf Hossain, SAJ Md Musa, Harish Kumar, Sudhansh Malhotra, Ziaul Matin, Neena Raina, Martin W Weber and Shams El Arifeen
    Citation: BMC Pediatrics 2012 12:197
  6. Antibiotic surveillance is mandatory to optimise antibiotic therapy. Our objectives were to evaluate antibiotic use in our pediatric intensive care unit (PICU) and to implement a simple achievable intervention...

    Authors: Martin Stocker, Eduardo Ferrao, Winston Banya, Jamie Cheong, Duncan Macrae and Anke Furck
    Citation: BMC Pediatrics 2012 12:196
  7. Burn injuries have a major impact on the patient’s physical and psychological functioning. The consequences can, especially in pediatric burns, persist long after the injury. A decrease in physical fitness see...

    Authors: Laurien M Disseldorp, Leonora J Mouton, Tim Takken, Marco Van Brussel, Gerard IJM Beerthuizen, Lucas HV Van der Woude and Marianne K Nieuwenhuis
    Citation: BMC Pediatrics 2012 12:195
  8. Celiac disease is defined as a ‘chronic small intestinal immune-mediated enteropathy precipitated by exposure to dietary gluten in genetically predisposed individuals’. Sweden has experienced an “epidemic” of ...

    Authors: Anna Myléus, Olle Hernell, Leif Gothefors, Marie-Louise Hammarström, Lars-Åke Persson, Hans Stenlund and Anneli Ivarsson
    Citation: BMC Pediatrics 2012 12:194
  9. Licensed for use in males in 2009, Human Papillomavirus (HPV) vaccination rates in adolescent males are extremely low. Literature on HPV vaccination focuses on females, adult males, or parents of adolescent ma...

    Authors: Andreia B Alexander, Nathan W Stupiansky, Mary A Ott, Debby Herbenick, Michael Reece and Gregory D Zimet
    Citation: BMC Pediatrics 2012 12:192
  10. Tuberculosis (TB) is a major cause of childhood morbidity and mortality in developing countries. One of the main difficulties is obtaining adequate specimens for bacteriological confirmation of the disease in ...

    Authors: Minime-Lingoupou Fanny, Narcisse Beyam, Jean Chrusostome Gody, G Zandanga, F Yango, Alexandre Manirakiza, Leen Rigouts, Catherine Pierre-Audigier, Brigitte Gicquel and Gustave Bobossi
    Citation: BMC Pediatrics 2012 12:191
  11. The northern territory Nunavut has Canada’s largest jurisdictional land mass with 33,322 inhabitants, of which 85% self-identify as Inuit. Nunavut has rates of infant mortality, postneonatal mortality and hosp...

    Authors: Sorcha A Collins, Padma Surmala, Geraldine Osborne, Cheryl Greenberg, Laakkuluk Williamson Bathory, Sharon Edmunds-Potvin and Laura Arbour
    Citation: BMC Pediatrics 2012 12:190
  12. Even minor abnormalities of early child development may have dramatic long term consequences. Accurate prevalence rates for a range of developmental impairments have been difficult to establish. Since related ...

    Authors: Heribert L Stich, Bernhard Th Baune, Riccardo N Caniato, Rafael T Mikolajczyk and Alexander Krämer
    Citation: BMC Pediatrics 2012 12:188
  13. The use of biomarkers has expanded considerably, as an alternative to questionnaire-based metrics of environmental tobacco smoke (ETS); few studies have assessed the affect of such alternative metrics on diver...

    Authors: Chris Carlsten, Helen Dimich-Ward, Anne DyBuncio, Allan B Becker and Moira Chan-Yeung
    Citation: BMC Pediatrics 2012 12:187
  14. The burden of disability is more severe among children in low income countries. Moreover, the number of children with disabilities (CWDs) in sub-Saharan Africa is predicted to increase with reduction in child ...

    Authors: Yoshito Kawakatsu, Satoshi Kaneko, Mohamed Karama and Sumihisa Honda
    Citation: BMC Pediatrics 2012 12:186
  15. The incidence of acute otitis media (AOM) vary from country to country. Geographical variations together with differences in study designs, reporting and settings play a role. We assessed the incidence of AOM ...

    Authors: Paola Marchisio, Luigi Cantarutti, Miriam Sturkenboom, Silvia Girotto, Gino Picelli, Daniele Dona, Antonio Scamarcia, Marco Villa and Carlo Giaquinto
    Citation: BMC Pediatrics 2012 12:185
  16. Oral clefts are one of the most common birth defects with significant medical, psychosocial, and economic ramifications. Oral clefts have a complex etiology with genetic and environmental risk factors. There a...

    Authors: George L Wehby, Norman Goco, Danilo Moretti-Ferreira, Temis Felix, Antonio Richieri-Costa, Carla Padovani, Fernanda Queiros, Camilla Vila Nova Guimaraes, Rui Pereira, Steve Litavecz, Tyler Hartwell, Hrishikesh Chakraborty, Lorette Javois and Jeffrey C Murray
    Citation: BMC Pediatrics 2012 12:184
  17. Despite changes in WHO guidelines, stavudine is still used extensively for treatment of pediatric HIV in the developing world. Lipoatrophy in sub-Saharan African children can be stigmatizing and have far-reach...

    Authors: Steve Innes, Mark F Cotton, Richard Haubrich, Maria M Conradie, Margaret van Niekerk, Clair Edson, Helena Rabie, Sonia Jain, Xiaoying Sun, Ekkehard W Zöllner, Stephen Hough and Sara H Browne
    Citation: BMC Pediatrics 2012 12:183
  18. Eustachian tube (ET) dysfunction plays an important role in the pathogenesis of acute otitis media (AOM). Unfortunately, there is a lack of knowledge about the exact role of the ET’s bony support, the temporal...

    Authors: Chantal Morin, Dominique Dorion, Jean-Marie Moutquin and Mélanie Levasseur
    Citation: BMC Pediatrics 2012 12:181
  19. Establishing healthy physical activity (PA) behaviours in early childhood is important for future PA behaviours. Parents play a central role in young children’s PA. However, there is currently little research ...

    Authors: Georgina F Bentley, Joanna K Goodred, Russell Jago, Simon J Sebire, Patricia J Lucas, Kenneth R Fox, Sarah Stewart-Brown and Katrina M Turner
    Citation: BMC Pediatrics 2012 12:180
  20. Studies on the association of birth by caesarean section (C/S) and allergies have produced conflicting findings. Furthermore, evidence on whether this association may differ in those at risk of atopy is limite...

    Authors: Ourania Kolokotroni, Nicos Middleton, Marina Gavatha, Demetris Lamnisos, Kostas N Priftis and Panayiotis K Yiallouros
    Citation: BMC Pediatrics 2012 12:179
  21. PEG-based laxatives are considered today the gold standard for the treatment of constipation in children. PEG formulations differ in terms of composition of inactive ingredients which may have an impact on acc...

    Authors: Francesco Savino, Serena Viola, Maiullari Erasmo, Giovanni Di Nardo, Salvatore Oliva and Salvatore Cucchiara
    Citation: BMC Pediatrics 2012 12:178
  22. Pediatric rehabilitation considers Family-centered service (FCS) as a way to increase participation of children with a physical disability in daily life. An important principal is that parents greatly contribu...

    Authors: Barbara Piškur, Anna JHM Beurskens, Marian J Jongmans, Marjolijn Ketelaar, Meghan Norton, Christina A Frings, Helena Hemmingsson and Rob JEM Smeets
    Citation: BMC Pediatrics 2012 12:177
  23. The ability of different obesity indices to predict cardiovascular risk is still debated in youth and few data are available in sub Saharan Africa. We compared the associations between several indices of obesi...

    Authors: Pascal Bovet, Tiphaine Arlabosse, Bharathi Viswanathan and Gary Myers
    Citation: BMC Pediatrics 2012 12:176
  24. Allergy represents a risk factor at the base of sleep-disordered breathing in pediatric age. Among allergic diseases, the atopy is characterized by a tendency to be “hyperallergic.” Sleep-disordered breathing ...

    Authors: Anna Maria Zicari, Giuseppe Marzo, Anna Rugiano, Camilla Celani, Maria Palma Carbone, Simona Tecco and Marzia Duse
    Citation: BMC Pediatrics 2012 12:175
  25. Evaluation of elementary writing skills in children is usually obtained with high resolution (and high cost) techniques or with low resolution pen-and-paper tests. In this observational study we tested a quant...

    Authors: Matteo Chiappedi, Rosella Togni, Elisabetta De Bernardi, Ilaria Maria Carlotta Baschenis, Sara Battezzato, Umberto Balottin, Elena Dalla Toffola and Maurizio Bejor
    Citation: BMC Pediatrics 2012 12:173
  26. Evaluation of palpable neck masses may be a diagnostic problem in pediatric patients, with differential diagnosis including congenital, inflammatory, tumoral and traumatic lesions. Ultrasonography is usually a...

    Authors: Vincenzo Davide Catania, Carlo Manzoni, Mariangela Novello, Libero Lauriola and Antonella Coli
    Citation: BMC Pediatrics 2012 12:172
  27. The objective of this work was to explore the impact on parents of the bronchiolitis hospitalization of their infant using the Impact of Bronchiolitis Hospitalization Questionnaire (IBHQ©).

    Authors: Alexandre Lapillonne, Antoine Regnault, Véronique Gournay, Jean-Bernard Gouyon, Hélène Gilet, Daniela Anghelescu, Tatiana Miloradovich, Benoit Arnould and Guy Moriette
    Citation: BMC Pediatrics 2012 12:171
  28. We assessed anthropometric status, breastfeeding duration, morbidity, and mortality outcomes during the first four years of life according to gestational age, in three population-based birth cohorts in the cit...

    Authors: Fernando C Barros, José Luis Diaz Rossello, Alicia Matijasevich, Samuel C Dumith, Aluisio J D Barros, Iná Silva dos Santos, Denise Mota and Cesar G Victora
    Citation: BMC Pediatrics 2012 12:169
  29. Severe eczema in young children is associated with an increased risk of developing asthma and rhino-conjunctivitis. In the general population, however, most cases of eczema are mild to moderate. In an unselect...

    Authors: Marit Saunes, Torbjørn Øien, Christian K Dotterud, Pål R Romundstad, Ola Storrø, Turid L Holmen and Roar Johnsen
    Citation: BMC Pediatrics 2012 12:168
  30. Children's fractures have been enlisted among orthopaedics complaints of childhood obesity. Unhealthy lifestyle behaviours may contribute to increased risk. This study described the prevalence of overweight/ob...

    Authors: Giuliana Valerio, Francesca Gallè, Caterina Mancusi, Valeria Di Onofrio, Pasquale Guida, Antonino Tramontano, Edoardo Ruotolo and Giorgio Liguori
    Citation: BMC Pediatrics 2012 12:166
  31. The number of new cases of type 1 diabetes mellitus (T1DM) has increased substantially in recent years and it is now one of the most common long-term endocrine disorders in childhood. In Sweden the child and f...

    Authors: Lisbeth Jönsson, Inger Hallström and Anita Lundqvist
    Citation: BMC Pediatrics 2012 12:165
  32. Human milk is the optimal nutrition for infants. When breastfeeding is not possible, supplementation of infant formula with long chain polyunsaturated fatty acids appears to promote neurodevelopmental outcome ...

    Authors: Maria Lorella Giannì, Paola Roggero, Charlotte Baudry, Amandine Ligneul, Daniela Morniroli, Francesca Garbarino, Pascale le Ruyet and Fabio Mosca
    Citation: BMC Pediatrics 2012 12:164
  33. Intestinal spirochetosis is an unusual infection in children and its clinical significance in humans is uncertain. The presence of these microorganisms in humans is well-known since the late 1800’s and was fir...

    Authors: Rossana Helbling, Maria-Chiara Osterheld, Bernard Vaudaux, Katia Jaton and Andreas Nydegger
    Citation: BMC Pediatrics 2012 12:163
  34. Anatomical progression of pediatric inflammatory bowel disease is under-reported. The aim of this work was to examine possible changes in the anatomical distribution of IBD in pediatric patients at diagnosis a...

    Authors: Jessica Tsang, Sheena Sikora, Donald Spady and Wael El-Matary
    Citation: BMC Pediatrics 2012 12:162
  35. An estimated 2.5 million children were living with HIV/AIDS at the end of 2009, 2.3 million (92%) in sub-Saharan Africa. Without treatment, a third of children with HIV will die of AIDS before their first birt...

    Authors: Digsu Negese Koye, Tadesse Awoke Ayele and Berihun Megabiaw Zeleke
    Citation: BMC Pediatrics 2012 12:161
  36. The Prevalence of liver disease among diabetics has been estimated to be between 17% and 100%. Most of these data were obtained from adult studies. The aim of our study was to screen for liver disease among ty...

    Authors: Abdulrahman A Al-Hussaini, Nimer M Sulaiman, Musa D AlZahrani, Ahmed S Alenizi and Mannan Khan
    Citation: BMC Pediatrics 2012 12:160
  37. Reducing neonatal death has been an emerging challenge in low and middle income countries in the past decade. The development of the low cost interventions and their effective delivery are needed to reduce dea...

    Authors: Ashish KC, Mats Målqvist, Johan Wrammert, Sheela Verma, Dhan Raj Aryal, Robert Clark, Naresh P KC, Ravi Vitrakoti, Kedar Baral and Uwe Ewald
    Citation: BMC Pediatrics 2012 12:159
  38. The Responsive Interdisciplinary Child-Community Health Education and Research (RICHER) initiative is an intersectoral and interdisciplinary community outreach primary health care (PHC) model. It is being unde...

    Authors: Sabrina T Wong, M Judith Lynam, Koushambhi B Khan, Lorine Scott and Christine Loock
    Citation: BMC Pediatrics 2012 12:158
  39. Human milk contains immune molecules involved in the protection of newborns against infections. We analyzed the concentration of Deleted in Malignant Brain Tumors 1 (DMBT1), a protein with functions in innate ...

    Authors: Sebastian Ronellenfitsch, Christel Weiß, David Frommhold, Lutz Koch, Jan Mollenhauer, Johannes Poeschl and Hanna Müller
    Citation: BMC Pediatrics 2012 12:157
  40. Currently over 50% of drugs prescribed to children have not been evaluated properly for use in their age group. One key reason why children have been excluded from clinical trials is that they are not consider...

    Authors: Irma M Hein, Pieter W Troost, Robert Lindeboom, Martine C de Vries, C Michel Zwaan and Ramón J L Lindauer
    Citation: BMC Pediatrics 2012 12:156
  41. Cerebral sparganosis in children is an extremely rare disease of central nervous system, and caused by a tapeworm larva from the genus of Spirometra. In this study, we discussed and summarized epidemiological,...

    Authors: Caigui Gong, Weihua Liao, Ashley Chineah, Xiaoyi Wang and Bob L Hou
    Citation: BMC Pediatrics 2012 12:155
  42. A critical factor shaping parental attitudes to vaccination is the parent’s interactions with health professionals. An effective interaction can address the concerns of vaccine supportive parents and motivate ...

    Authors: Julie Leask, Paul Kinnersley, Cath Jackson, Francine Cheater, Helen Bedford and Greg Rowles
    Citation: BMC Pediatrics 2012 12:154
  43. The Institute of Medicine has prioritized shared decision making (SDM), yet little is known about the impact of SDM over time on behavioral outcomes for children. This study examined the longitudinal associati...

    Authors: Alexander G Fiks, Stephanie Mayne, A Russell Localio, Chris Feudtner, Evaline A Alessandrini and James P Guevara
    Citation: BMC Pediatrics 2012 12:153

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