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  1. Pain is a common symptom in children receiving hospital care. Adequate pain management in paediatric patients is of the utmost importance. Few studies have investigated children’s own experiences of pain durin...

    Authors: Viveka Andersson, Stefan Bergman, Ingela Henoch, Hanna Simonsson and Karin Ahlberg
    Citation: BMC Pediatrics 2022 22:252
  2. The incidences of early term and late preterm birth have increased worldwide during recent years. However, there is a lack of prospective study about the influence of early term and late preterm birth on infan...

    Authors: Zhong Chen, Chao Xiong, Hua Liu, Junyu Duan, Chun Kang, Cong Yao, Kai Chen, Yawen Chen, Yan Liu, Mingzhu Liu and Aifen Zhou
    Citation: BMC Pediatrics 2022 22:251
  3. There is a possibility that excess body fat affects bone mass gain and may compromise skeletal health in obese children. The purpose of the study was to identify the relationship between bone mineral density (...

    Authors: Samantha López-Peralta, Enrique Romero-Velarde, Edgar M. Vásquez-Garibay, Mercedes González-Hita, Laura C. Robles-Robles, Francisco J. Ruiz-González and Misael Alejandro Pérez-Romero
    Citation: BMC Pediatrics 2022 22:249
  4. This case report describes a child born with both cystic fibrosis (CF) and alpha-1 antitrypsin deficiency (A1ATD). Both are autosomal recessive inherited diseases, mainly affecting the lungs and the liver. The...

    Authors: Evi Jaspers, Ine Van Dijck, Ilse Hoffman, Noël Knops, Xavier Stéphenne, Peter Witters and Marijke Proesmans
    Citation: BMC Pediatrics 2022 22:247
  5. Hirschsprung disease (HSCR) is a common congenital disorder presenting with functional obstruction due to aganglionosis of the colon. There are numerous types of pull-through surgery for managing HSCR, such as...

    Authors: Gunadi, Theodora Monica Carissa, Stevie, Ezzah Fatmala Daulay, Dicky Yulianda, Kristy Iskandar and Andi Dwihantoro
    Citation: BMC Pediatrics 2022 22:246
  6. The association between anthropometric measures and dietary fat quality indices is unclear in pediatric age groups. The present study aimed to assess the association between dietary lipophilic index (LI) and t...

    Authors: Maedeh Mozafarinia, Motahar Heidari-Beni, Behnood Abbasi and Roya Kelishadi
    Citation: BMC Pediatrics 2022 22:244
  7. Hyperbilirubinemia is the main mechanism that causes neonatal jaundice, and genetics is one of the risk factors of hyperbilirubinemia. Therefore, this study aims to explore the correlation between two genes, UGT1...

    Authors: Chalirmporn Atasilp, Janjira Kanjanapipak, Jaratdao Vichayaprasertkul, Pimonpan Jinda, Rawiporn Tiyasirichokchai, Pornpen Srisawasdi, Chatchay Prempunpong, Monpat Chamnanphon, Apichaya Puangpetch, Natchaya Vanwong, Suwit Klongthalay, Thawinee Jantararoungtong and Chonlaphat Sukasem
    Citation: BMC Pediatrics 2022 22:243
  8. The aim of this study was to investigate the effect of kangaroo mother care (KMC) by mother and her surrogate on nutritional behavior and physiological function of preterm neonates.

    Authors: Mahboubeh Jamehdar, Roghaiyeh Nourizadeh, Aboulhassan Divband, Leila Valizadeh, Mohammadbagher Hosseini and Sevil Hakimi
    Citation: BMC Pediatrics 2022 22:242
  9. Multisystem inflammatory syndrome is a severe manifestation of SARS-CoV-2 in children. The incidence of MIS-C after infection is poorly understood. There are very few cohorts describing MIS-C in Africa despite...

    Authors: Claire Butters, Deepthi Raju Abraham, Raphaella Stander, Heidi Facey-Thomas, Debbie Abrahams, Ayodele Faleye, Nazneen Allie, Khushbu Soni, Helena Rabie, Christiaan Scott, Liesl Zühlke and Kate Webb
    Citation: BMC Pediatrics 2022 22:241
  10. Despite inter-individual variations in pubertal timing, growth references are conventionally constructed relative to chronological age (C-age). Thus, they are based on reference populations containing a mix of...

    Authors: Kerstin Albertsson-Wikland, Aimon Niklasson, Lars Gelander, Anton Holmgren and Andreas F. M. Nierop
    Citation: BMC Pediatrics 2022 22:238
  11. Venous cannulation is among the most stressful and painful experiences of children hospitalization. Children with thalassemia need regular blood transfusion which needs venous access each time. The quality of ...

    Authors: Masoomeh Ghasemi, Poria Hoseinialiabadi, Fatemeh Yazdanpanah, Maryam Askaryzadeh Mahani, Leila Malekyan, Kazem Najafi, Mohammadreza Arab, Mansour Arab and Hadi Ranjbar
    Citation: BMC Pediatrics 2022 22:237
  12. Evidence has shown that higher levels of physical fitness (PF) in youth have beneficial effects on adult health-related outcomes. However, the tracking of separate PF components during adolescence has been les...

    Authors: Mario Kasović, Ana Oreški, Tomaš Vespalec, Kateřina Jenčíková and Lovro Štefan
    Citation: BMC Pediatrics 2022 22:236
  13. The epidemiology of Pediatric Hip Arthroplasty (PHA) is unclear. Prevalence of PHA in Europe was reported in Scandinavian registries, but data on this procedure are not described in other countries. Therefore,...

    Authors: Umile Giuseppe Longo, Rocco Papalia, Sergio De Salvatore, Laura Ruzzini, Ilaria Piergentili, Giuseppe Salvatore, Vincenzo Candela and Vincenzo Denaro
    Citation: BMC Pediatrics 2022 22:235
  14. To investigate hypothalamic-pituitary-thyroid function in children of different ages, nutritional phases, and genotypes that were diagnosed with Prader-Willi syndrome (PWS), as well as the effects of recombina...

    Authors: Xinjiang Huang, Xi Yin, Dongyan Wu, Yanna Cai, Xiuzhen Li, Wen Zhang, Chunhua Zeng, Xiaojian Mao and Li Liu
    Citation: BMC Pediatrics 2022 22:234
  15. Transcobalamin deficiency is a rare inborn metabolic disorder, characterized by pancytopenia, megaloblastic anemia, failure to thrive, diarrhea, and psychomotor retardation.

    Authors: Pongpak Pongphitcha, Nongnuch Sirachainan, Arthaporn Khongkraparn, Thipwimol Tim-Aroon, Duantida Songdej and Duangrurdee Wattanasirichaigoon
    Citation: BMC Pediatrics 2022 22:233
  16. The relationship between the Body Mass Index (BMI) with physical fitness in children and adolescent populations from diverse regions are consistent. However, the relationship between the Ponderal Index (PI) wi...

    Authors: Marco Cossio-Bolaños, Rubén Vidal- Espinoza, Camilo Urra Albornoz, José Fuentes-Lopez, Lucila Sánchez-Macedo, Cynthia Lee Andruske, José Sulla-Torres and Rossana Gómez Campos
    Citation: BMC Pediatrics 2022 22:231
  17. Previous studies have addressed the effects of different exercises and modalities on forward head posture (FHP), but the minimal clinically important difference (MCID) of the effect of exercises on FHP remains...

    Authors: Zahra Heydari, Rahman Sheikhhoseini, Shahnaz Shahrbanian and Hashem Piri
    Citation: BMC Pediatrics 2022 22:230
  18. More than 2 years into the COVID-19 pandemic, SARS-CoV-2 still impacts children’s health and the management of pediatric hospitals. However, it is unclear which hygiene and infection control measures are effec...

    Authors: Jonathan Remppis, Johannes Hilberath, Tina Ganzenmüller, Christoph Slavetinsky, Malte Kohns Vasconcelos, Marion Gnädig, Jan Liese, Siri Göpel, Peter Lang, Oliver Heinzel and Hanna Renk
    Citation: BMC Pediatrics 2022 22:229
  19. Group A Streptococcus has been recognized as an important human pathogen and it remains among the top ten causes of mortality from an infectious disease. Group A Streptococcus throat carriage plays an important r...

    Authors: Shamil Barsenga, Habtamu Mitiku, Tewodros Tesfa and Tadesse Shume
    Citation: BMC Pediatrics 2022 22:227
  20. Procalcitonin (PCT) offers better specificity than C-reactive protein (CRP) to detect SBI. However, their cost limited their use and routine application. The objective of this work is to determine the cost-eff...

    Authors: Jefferson Antonio Buendía and Diana Guerrero Patiño
    Citation: BMC Pediatrics 2022 22:226
  21. Parenteral Nutrition (PN) is preferred when patient is unable to eat. Most clinically widely used lipid emulsion is now attracting more attention in its stability and adverse reactions. We report here the firs...

    Authors: Lihua Yuan, Tao Li, Lijuan Yuan, Feng Chen, Jinchun Qiu and Xing Ji
    Citation: BMC Pediatrics 2022 22:224
  22. The risk of Congenital Heart Defects (CHD) is greatly influenced by variants within the genes involved in folate-homocysteine metabolism. Polymorphism in MTHFR (C677T and G1793A) and MS/MTR (A2756G) genes incr...

    Authors: Jyotdeep Kour Raina, Rakesh Kumar Panjaliya, Vikas Dogra, Sushil Sharma, Anupriya and Parvinder Kumar
    Citation: BMC Pediatrics 2022 22:223
  23. Mutations in PIGN, resulting in a glycosylphosphatidylinositol (GPI) anchor deficiency, typically leads to multiple congenital anomalies-hypotonia-seizures syndrome. However, the link between PIGN and epilepsy or...

    Authors: Maoqiang Tian, Jing Chen, Juan Li, Hong Pan, Wenting Lei and Xiaomei Shu
    Citation: BMC Pediatrics 2022 22:222
  24. Malnutrition is a critical public health issue that has been related to a significant increase in mortality and morbidity rates. Despite the fact that children are expected to benefit from home gardening produ...

    Authors: Mulat Tirfie Bayih, Zerfalem Arega and Achenef Motbainor
    Citation: BMC Pediatrics 2022 22:221
  25. Interventions to promote breakfast consumption are a popular strategy to address early life inequalities. It is important to understand the epidemiology of children and adolescents who skip breakfast so that i...

    Authors: Alanna Sincovich, Hero Moller, Lisa Smithers, Mary Brushe, Zohra S. Lassi, Sally A. Brinkman and Tess Gregory
    Citation: BMC Pediatrics 2022 22:220
  26. According to the Feeding Infants and Toddlers Study (FITS), the percentage of older infants consuming infant cereal has declined from 72% of 6–11.9 month old infants in 2002 to 52% in 2016. This is especially ...

    Authors: Kristen Finn, Sarah Quick, Andrea Anater, Joel Hampton, Brian Kineman and William Klish
    Citation: BMC Pediatrics 2022 22:219
  27. In low to middle-income countries where home births are common and neonatal postnatal care is limited, community health worker (CHW) home visits can extend the capability of health systems to reach vulnerable ...

    Authors: Farjana Jahan, Eric Foote, Mahbubur Rahman, Abul Kasham Shoab, Sarker Masud Parvez, Mizanul Islam Nasim, Rezaul Hasan, Shams El Arifeen, Sk Masum Billah, Supta Sarker, Md. Mahbubul Hoque, Mohammad Shahidullah, Muhammad Shariful Islam, Sabina Ashrafee and Gary L. Darmstadt
    Citation: BMC Pediatrics 2022 22:218
  28. The role of serum Procalcitonin (PCT) in adults in diagnosis of Community acquired pneumonia (CAP) is well established, however, role in pediatric CAP remains controversial.

    Authors: Vinod H. Ratageri, Puspha Panigatti, Aparna Mukherjee, Rashmi R. Das, Jagdish Prasad Goyal, Javeed Iqbal Bhat, Bhadresh Vyas, Rakesh Lodha, Deepak Singhal, Prawin Kumar, Kuldeep Singh, Samarendra Mahapatro, Bashir Ahmad Charoo, S. K. Kabra and K. R. Jat
    Citation: BMC Pediatrics 2022 22:217
  29. Hirschsprung disease (HSCR) is a complex genetic disorder characterized by the lack of ganglion cells in the intestines. A current study showed that the NRG1 rare variant frequency in Indonesian patients with HSC...

    Authors: Gunadi, Alvin Santoso Kalim, Marcellus, Nova Yuli Prasetyo Budi and Kristy Iskandar
    Citation: BMC Pediatrics 2022 22:216
  30. The timing of adiposity peak (AP) or adiposity rebound (AR) is a determinant of overweight or obesity in adolescence and adulthood. However, limited studies have reported the association in young school-age ch...

    Authors: Dan Lin, Di-di Chen, Jun Huang, Yun Li, Xiao-sa Wen and Hui-jing Shi
    Citation: BMC Pediatrics 2022 22:215
  31. Orofacial clefts (OFCs) are the commonest congenital anomalies of the head and neck. Their aetiology is multifactorial, and prevalence has a geographical variation. This study sought to describe OFC cases that...

    Authors: Prosperity A. Sithole, Palesa Motshabi-Chakane and Michel K. Muteba
    Citation: BMC Pediatrics 2022 22:214
  32. Early morning sunlight exposure for infants is a good practice to prevent rickets and alleviate the problem of vitamin D deficiency. Rickets is a major public health problem in many countries especially in dev...

    Authors: Eyasu Alem Lake, Birhanu Wondimeneh Demissie, Natneal Atnafu Gebeyehu, Gedion Asnake Azeze, Kelemu Abebe Gelaw, Robera Olana Fite, Lielt Gebreselassie Gebrekirstos, Tesfaye Yitna Chichiabellu and Mistire Teshome Guta
    Citation: BMC Pediatrics 2022 22:213
  33. Risky media use in terms of accumulating too much time in front of screens and usage before bedtime in early childhood is linked to developmental delays, reduced sleep quality, and unhealthy media use in later...

    Authors: C. Fitzpatrick, M. L Almeida, E. Harvey, G. Garon-Carrier, F. Berrigan and M Asbridge
    Citation: BMC Pediatrics 2022 22:212
  34. Necrotizing enterocolitis (NEC) is one of serious gastrointestinal inflammatory diseases in newborn infants, with a high morbidity and mortality. Red blood cell transfusion (RBCT) plays a controversial and dou...

    Authors: Lijuan Luo, Xingling Liu, Huan Yu, Mei Luo, Wen Jia, Wenbin Dong and Xiaoping Lei
    Citation: BMC Pediatrics 2022 22:211
  35. Although advance care planning (ACP) has been widely recommended to support patient and family engagement in understanding the patient’s values, preferences and goals of care, there are only a few models in pa...

    Authors: Anne van Driessche, Joni Gilissen, Aline De Vleminck, Marijke Kars, Jurrianne Fahner, Jutte van der Werff ten Bosch, Luc Deliens, Joachim Cohen and Kim Beernaert
    Citation: BMC Pediatrics 2022 22:210
  36. Childhood overweight and obesity is one of the most challenging public health problems facing both developed and developing countries. Several studies carried worldwide assessed predisposing risk factors for c...

    Authors: Helene Barbe Zoghby, Elsa Sfeir, Marwan Akel, Diana Malaeb, Sahar Obeid and Souheil Hallit
    Citation: BMC Pediatrics 2022 22:209
  37. The problem of cardiovascular diseases and lack of adequate information about the blood pressure profiles among children in South Africa has enormous consequences for public health and the general well-being o...

    Authors: Howard Gomwe, Eunice Seekoe, Philemon Lyoka and Chioneso Show Marange
    Citation: BMC Pediatrics 2022 22:207
  38. Precision treatment of pediatric diabetic ketoacidosis (DKA) has been the focus of research for decades. Whether the timing of the initiation of dietary intake contributes to DKA correction is ignored.

    Authors: Xuewen Yuan, Jieguo Wang, Xiaofeng Chen, Wu Yan, Qing Niu, Ning Tang, Ming Zhi Zhang, Wei Gu and Xu Wang
    Citation: BMC Pediatrics 2022 22:206
  39. Even though child mortality decreased greatly (44%, since 1990), children in developing countries are eight times more likely to die before they attain their five years birthday. When comparing under-five mort...

    Authors: Nigusie Selomon Tibebu, Tigabu Desie Emiru, Chalie Marew Tiruneh, Adane Birhanu Nigat, Moges wubneh Abate, Bisrat Dessie Getu and Amsalu Belete Mekonnen
    Citation: BMC Pediatrics 2022 22:205
  40. Acute otitis media (AOM) remains a common infection in children despite the introduction of pneumococcal conjugate vaccines. This study estimated AOM incidence rates (IRs) over time in children < 16 years old ...

    Authors: Tianyan Hu, Bélène Podmore, Rosemarie Barnett, Dominik Beier, Wolfgang Galetzka, Nawab Qizilbash, Dennis Haeckl, Jessica Weaver, Timo Boellinger, Sarah Mihm and Tanaz Petigara
    Citation: BMC Pediatrics 2022 22:204
  41. During 2019, neonatal conditions in Ethiopia accounted for 55% of under-5 deaths, with 33 neonatal deaths occurring for every 1000 live births. More than 80% of all newborns deaths are caused by preventable an...

    Authors: Bizuhan Gelaw Birhanu and Johanna Mmabojalwa Mathibe-Neke
    Citation: BMC Pediatrics 2022 22:203
  42. This study provides Dutch national norms for the parent-reported Strengths and Difficulties Questionnaire (SDQ) for children aged 3-14 years, and assesses the test performance of the SDQ Total Difficulties Sca...

    Authors: Meinou H. C. Theunissen, Marianne S. de Wolff, Iris Eekhout, Cathelijne L. Mieloo, Lisanne L. Stone and Sijmen A. Reijneveld
    Citation: BMC Pediatrics 2022 22:202
  43. Bronchopulmonary dysplasia (BPD) is one of the most common adverse consequence of premature delivery and the most common chronic lung disease in infants. BPD is associated with long-term lung diseases and neur...

    Authors: Tingting Yang, Qianqian Shen, Siyu Wang, Tianfang Dong, Liang Liang, Fan Xu, Youfang He, Chunlei Li, Fang Luo, Jiahong Liang, Chunhui Tang and Jinghui Yang
    Citation: BMC Pediatrics 2022 22:200

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