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  1. Hypophosphatasia (HP) is characterized by a genetic defect in the tissue-nonspecific alkaline phosphatase (TNSALP) gene and predominantly an autosomal recessive trait. HP patients suffer from reduced bone mine...

    Authors: Hermann J Girschick, Etienne Mornet, Meinrad Beer, Monika Warmuth-Metz and Peter Schneider
    Citation: BMC Pediatrics 2007 7:3
  2. Documentation of superfoetation is extremely rare in humans., The younger foetus has invariably been small for gestational age (estimated from the date of the last menstrual bleed) in all the cases reported in...

    Authors: Noopur Baijal, Mohit Sahni, Neeraj Verma, Amit Kumar, Nittin Parkhe and Jacob M Puliyel
    Citation: BMC Pediatrics 2007 7:2
  3. Implementation of health research findings is important for medicine to be evidence-based. Previous studies have found variation in the information sources thought to be of greatest importance to clinicians bu...

    Authors: Teresa H Jones, Steve Hanney and Martin J Buxton
    Citation: BMC Pediatrics 2007 7:1
  4. Researchers and clinicians are seeking to develop efficacious behavioral interventions to treat overweight children; however, few studies have documented the behavioral correlates of overweight children in com...

    Authors: Shelagh A Mulvaney, Kristine L Kaemingk, James L Goodwin and Stuart F Quan
    Citation: BMC Pediatrics 2006 6:34
  5. The purpose of this study was to determine the prevalence of high blood pressure (HBP) and associated risk factors in school children 8 to 13 years of age.

    Authors: Ximena Urrutia-Rojas, Christie U Egbuchunam, Sejong Bae, John Menchaca, Manuel Bayona, Patrick A Rivers and Karan P Singh
    Citation: BMC Pediatrics 2006 6:32
  6. In 1999, the American Academy of Pediatrics and U.S. Public Health Service recommended suspending the birth dose of hepatitis B vaccine due to concerns about potential mercury exposure. A previous report found...

    Authors: Nancy D Lin, Ken Kleinman, K Arnold Chan, Xian-Jie Yu, Eric K France, Feifei Wei, John P Mullooly, Steven Black, David K Shay, Margarette Kolczak and Tracy A Lieu
    Citation: BMC Pediatrics 2006 6:31
  7. Childhood injury is the leading cause of mortality, morbidity and permanent disability in children in the developed world. This research examines relationships between socio-economic status (SES), demographics...

    Authors: Susan J Gilbride, Cameron Wild, Douglas R Wilson, Lawrence W Svenson and Donald W Spady
    Citation: BMC Pediatrics 2006 6:30
  8. Because of the paucity of effective evidence-based therapies for children with recurrent abdominal pain, we evaluated the therapeutic effect of guided imagery, a well-studied self-regulation technique.

    Authors: Joy A Weydert, Daniel E Shapiro, Sari A Acra, Cynthia J Monheim, Andrea S Chambers and Thomas M Ball
    Citation: BMC Pediatrics 2006 6:29
  9. Point of care (POC) glucose meters are routinely used as a screening tool for hypoglycemia in a neonatal setting. Glucose meters however, lack the same accuracy as laboratory instruments for glucose measuremen...

    Authors: Cynthia Balion, Vijaylaxmi Grey, Afisi Ismaila, Susan Blatz and Wendy Seidlitz
    Citation: BMC Pediatrics 2006 6:28
  10. For centuries, sunlight has been used for therapeutic purposes. Parents still sun their infants to treat neonatal jaundice, nappy rash or mostly to supply vitamin D for bone development as a consequence of hea...

    Authors: Nihal Aladag, Tuncay M Filiz, Pinar Topsever and Suleyman Gorpelioglu
    Citation: BMC Pediatrics 2006 6:27
  11. Our goal was to quantify the evidence that is available to the physicians of a pediatric emergency department (PED) in making treatment decisions. Further, we wished to ascertain what percentage of evidence fo...

    Authors: Kellie L Waters, Natasha Wiebe, Kristie Cramer, Lisa Hartling and Terry P Klassen
    Citation: BMC Pediatrics 2006 6:26
  12. Cystic fibrosis (CF) is caused by mutations in the gene encoding for the CF transmembrane conductance regulator (CFTR) protein, which acts as a chloride channel after activation by cyclic AMP (cAMP). Newborn s...

    Authors: Isabelle Sermet-Gaudelus, Delphine Roussel, Stéphanie Bui, Eric Deneuville, Frédéric Huet, Philippe Reix, Gabriel Bellon, Gérard Lenoir and Aleksander Edelman
    Citation: BMC Pediatrics 2006 6:25
  13. Birth weight is a composite of skeletal size and soft tissue. These components are likely to have different growth patterns. The aim of this paper is to investigate the association between established determin...

    Authors: Beverley M Shields, Bridget A Knight, Roy J Powell, Andrew T Hattersley and David E Wright
    Citation: BMC Pediatrics 2006 6:24
  14. Previous studies regarding the use of information technologies (IT) specifically among pediatricians and other physicians who treat children are lacking. As such, the objective of this study is to examine the ...

    Authors: Nir Menachemi, Donna L Ettel, Robert G Brooks and Lisa Simpson
    Citation: BMC Pediatrics 2006 6:21
  15. Adverse cardiorespiratory events including apnea, bradycardia, and desaturations have been described following administration of the first diphtheria-tetanus-pertussis-inactivated polio-Haemophilus influenzae typ...

    Authors: Jackie Lee, Joan L Robinson and Donald W Spady
    Citation: BMC Pediatrics 2006 6:20
  16. In view of the fact that a significant proportion of neonates with malaria may be missed on our wards on the assumption that the disease condition is rare, this study aims at documenting the prevalence of mala...

    Authors: Iyabo T Runsewe-Abiodun, Olusoga B Ogunfowora and Bolanle M Fetuga
    Citation: BMC Pediatrics 2006 6:19
  17. To determine the validity of the recently developed child-specific thoracic gas volume (TGV) prediction equations for use in air-displacement plethysmography (ADP) in diverse pediatric populations.

    Authors: Paul B Higgins, Analiza M Silva, Luis B Sardinha, Holly R Hull, Michael I Goran, Barbara A Gower and David A Fields
    Citation: BMC Pediatrics 2006 6:18
  18. It has recently been suggested that serum procalcitonin (PCT) is of value in the diagnosis of neonatal sepsis, with varying results. The aim of this prospective multicenter study was to assess the usefulness o...

    Authors: José B López Sastre, David Pérez Solís, Vicente Roqués Serradilla, Belén Fernández Colomer, Gil D Coto Cotallo, Xavier Krauel Vidal, Eduardo Narbona López, Manuel García del Río, Manuel Sánchez Luna, Antonio Belaustegui Cueto, Manuel Moro Serrano, Alfonso Urbón Artero, Emilio Álvaro Iglesias, Ángel Cotero Lavín, Eduardo Martínez Vilalta and Bartolomé Jiménez Cobos
    Citation: BMC Pediatrics 2006 6:16
  19. The patent ductus arteriosus (PDA) is an important problem in premature infants. Surgical PDA ligation is usually only be considered when medical treatment has either failed or was contraindicated. The aims of...

    Authors: LLeona CL Lee, Angela Tillett, Robert Tulloh, Robert Yates and Wilf Kelsall
    Citation: BMC Pediatrics 2006 6:15
  20. The hard edges of adult finger clip probes of the pulse oximetry oxygen saturation (POOS) monitor can cause skin damage if used for prolonged periods in a neonate. Covering the skin under the probe with Microp...

    Authors: Jyotsna James, Lokesh Tiwari, Pramod Upadhyay, Vishnubhatla Sreenivas, Vikas Bhambhani and Jacob M Puliyel
    Citation: BMC Pediatrics 2006 6:14
  21. ACOG states meconium stained amniotic fluid (MSAF) as one of the historical indicators of perinatal asphyxia. Thick meconium along with other indicators is used to identify babies with severe intrapartum asphy...

    Authors: Rishi Kant Ojha, Saroj K Singh, Sanjay Batra, V Sreenivas and Jacob M Puliyel
    Citation: BMC Pediatrics 2006 6:13
  22. Thyroid hormone plays a crucial role in the growth and function of the central nervous system. The purpose of the study was to examine the relationships between the status of subclinical thyroid conditions and...

    Authors: Tiejian Wu, Joanne W Flowers, Fred Tudiver, Jim L Wilson and Natavut Punyasavatsut
    Citation: BMC Pediatrics 2006 6:12
  23. SRY (sex-determining region, Y) is the gene responsible of gonadal differentiation in the male and it is essential for the regular development of male genitalia. Translocations involving the human sex chromosome...

    Authors: M Ellaithi, D Gisselsson, T Nilsson, S Abd El-Fatah, T Ali, A Elagib, ME Ibrahim and I Fadl-Elmula
    Citation: BMC Pediatrics 2006 6:11
  24. We aimed to investigate incidence rates of urinary tract infections in Dutch general practice and their association with gender, season and urbanisation level, and to analyse prescription and referral in case ...

    Authors: Wing-Yee Kwok, Marjolein CE de Kwaadsteniet, Mirjam Harmsen, Lisette WA van Suijlekom-Smit, François G Schellevis and Johannes C van der Wouden
    Citation: BMC Pediatrics 2006 6:10
  25. The contribution of birth defects, including cleft lip and palate, to neonatal and infant mortality and morbidity is substantial. As other mortality and morbidity causes including infections, hygiene, prematur...

    Authors: George L Wehby, Eduardo E Castilla, Norman Goco, Monica Rittler, Viviana Cosentino, Lorette Javois, Ann Marie McCarthy, Georgiy Bobashev, Stephen Litavecz, Alejandra Mariona, Graca Dutra, Jorge S López-Camelo, Iêda M Orioli and Jeffrey C Murray
    Citation: BMC Pediatrics 2006 6:9
  26. Monitoring plasma gentamicin concentrations in neonates 24 hours after a once daily dose (4 mg/kg) often necessitates additional blood sampling. In adults a nomogram has been developed enabling evaluation of g...

    Authors: Elaine M Boyle, Isobel Brookes, Kathy Nye, Mike Watkinson and F Andrew I Riordan
    Citation: BMC Pediatrics 2006 6:8
  27. Early detection and treatment of neonatal hyperbilirubinemia is important in the prevention of bilirubin-induced encephalopathy. In this study, we evaluated the New Jersey pediatricians' practices and beliefs ...

    Authors: Anna Petrova, Rajeev Mehta, Gillian Birchwood, Barbara Ostfeld and Thomas Hegyi
    Citation: BMC Pediatrics 2006 6:6
  28. Bacille Calmette-Guérin (BCG) vaccine is given to Canadian Aboriginal neonates in selected communities. Severe reactions and deaths associated with BCG have been reported among infants born with immunodeficien...

    Authors: Michael Clark and D William Cameron
    Citation: BMC Pediatrics 2006 6:5
  29. There are no prospective studies that have examined for chronic cough in children without lung disease but with gastroesophageal reflux (GER). In otherwise healthy children undergoing flexible upper gastrointe...

    Authors: Anne B Chang, Nancy C Cox, Joan Faoagali, Geoffrey J Cleghorn, Christopher Beem, Looi C Ee, Geoffrey D Withers, Mark K Patrick and Peter J Lewindon
    Citation: BMC Pediatrics 2006 6:4
  30. Our primary purpose was to determine the normal range and variability of blood volume (BV) in healthy children, in order to provide reference values during childhood and adolescence. Our secondary aim was to c...

    Authors: Ann Raes, Sarah Van Aken, Margarita Craen, Raymond Donckerwolcke and Johan Vande Walle
    Citation: BMC Pediatrics 2006 6:3
  31. Recent reports have documented a leveling-off of survival rates in preterm infants through the 1990's. The objective of this study was to determine temporal changes in illness severity in very low birth weight...

    Authors: David A Paul, Kathleen H Leef, Robert G Locke, Louis Bartoshesky, Judy Walrath and John L Stefano
    Citation: BMC Pediatrics 2006 6:2
  32. A number of infant pain measures have been developed over the past 15 years incorporating behavioural and physiologic indicators; however, no reliable or valid measure exists for infants who are at risk for ne...

    Authors: Bonnie Stevens, Patrick McGrath, Janet Yamada, Sharyn Gibbins, Joseph Beyene, Lynn Breau, Carol Camfield, Allen Finley, Linda Franck, Alexandra Howlett, Celeste Johnston, Patricia McKeever, Karel O'Brien and Arne Ohlsson
    Citation: BMC Pediatrics 2006 6:1
  33. Coagulase negative staphylococcus (CONS) is the main cause of late-onset sepsis in Neonatal Intensive Care Units (NICU). Although CONS rarely causes fulminant sepsis, vancomycin is frequently used as empiric t...

    Authors: Sarah L Lawrence, Virginia Roth, Robert Slinger, Baldwin Toye, Isabelle Gaboury and Brigitte Lemyre
    Citation: BMC Pediatrics 2005 5:49
  34. The condition of obesity has become a significant public health problem in the United States. In children and adolescents, the prevalence of overweight has tripled in the last 20 years, with approximately 16.0...

    Authors: Carol Curtin, Linda G Bandini, Ellen C Perrin, David J Tybor and Aviva Must
    Citation: BMC Pediatrics 2005 5:48
  35. Subacute Sclerosing Panencephalitis (SSPE) is so rare in developed countries with measles immunization programs that national active surveillance is now needed to capture sufficient number of cases for meaning...

    Authors: Craig Campbell, Simon Levin, Peter Humphreys, Wikke Walop and Renee Brannan
    Citation: BMC Pediatrics 2005 5:47
  36. Anaemia is highly prevalent in children of developing countries. It is associated with impaired physical growth and mental development. Palmar pallor is recommended at primary level for diagnosing it, on the b...

    Authors: Juan P Chalco, Luis Huicho, Carlos Alamo, Nilton Y Carreazo and Carlos A Bada
    Citation: BMC Pediatrics 2005 5:46
  37. Care procedures for preventing neonatal diseases are carried out according to nurseries' traditions and may be not consistent with the evidence based medicine issues.

    Authors: Andrea Guala, Roberta Guarino, Mauro Zaffaroni, Claudio Martano, Claudio Fabris, Guido Pastore and Gianni Bona
    Citation: BMC Pediatrics 2005 5:45
  38. The introduction of pneumococcal conjugate vaccine (PCV) to the U.S. recommended childhood immunization schedule in the year 2000 added three injections to the number of vaccinations a child is expected to rec...

    Authors: Nancy D Lin, Ken Kleinman, K Arnold Chan, Xian-Jie Yu, Eric K France, Stanley Xu, Feifei Wei, John Mullooly, Jeanne Santoli and Tracy A Lieu
    Citation: BMC Pediatrics 2005 5:43
  39. The Complete Blood Count (CBC) is a test frequently performed on children presenting to the Pediatric Emergency Department (PED), usually for the evaluation of an infectious illness. The CBC also allows for sc...

    Authors: Martin V Pusic, Brenda J Dawyduk and David Mitchell
    Citation: BMC Pediatrics 2005 5:42
  40. The increased survival of preterm and very low birth weight infants in recent years has been well documented but continued surveillance is required in order to monitor the effects of new therapeutic interventi...

    Authors: Huw P Jones, Stella Karuri, Catherine MG Cronin, Arne Ohlsson, Abraham Peliowski, Anne Synnes and Shoo K Lee
    Citation: BMC Pediatrics 2005 5:40
  41. Bronchitis obliterans is a severe and extremely rare complication of respiratory tract infections in children and is characterized by massive atelectasis and collapse of the affected lung. Of the rare cases re...

    Authors: Elke Govaere, Dirk Van Raemdonck, Hugo Devlieger, Maria-Helena Smet, Eric Verbeken, Marijke Proesmans and Kris De Boeck
    Citation: BMC Pediatrics 2005 5:39
  42. The delivery of optimal medical care to children is dependent on the availability of child relevant research. Our objectives were to: i) systematically review and describe how children are handled in reviews o...

    Authors: Kristie Cramer, Natasha Wiebe, Virginia Moyer, Lisa Hartling, Katrina Williams, George Swingler and Terry P Klassen
    Citation: BMC Pediatrics 2005 5:38

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