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  1. Research on myelin oligodendrocyte glycoprotein antibody (MOG-Ab)-associated disease (MOGAD) among Chinese children is relatively rare. Therefore, this study aimed to explore and analyze the clinical character...

    Authors: Xiaoang Sun, Meiyan Liu, Xiaona Luo, Fang Yuan, Chunmei Wang, Simei Wang, Quanmei Xu, Yuanfeng Zhang and Yucai Chen
    Citation: BMC Pediatrics 2022 22:666
  2. Dental trauma is common among children. It has negative effects on a child’s quality of life. Parental knowledge, especially among mothers is an important factor for the long-term success of this emergency. Th...

    Authors: Zahra Momeni, Sanaz Afzalsoltani and Mahmoudreza Moslemzadehasl
    Citation: BMC Pediatrics 2022 22:665
  3. The incidence of early-onset vitamin K deficiency bleeding (VKDB) in at-risk neonates who did not receive vitamin K supplementation varied from 6 to 12%. This case report aims to show that VKDB can occur abrup...

    Authors: Harapan Parlindungan Ringoringo, Katherine Richel Tambunan, Fajar Khalis Ananda, Felynawati Nawati and Yanuar Nusca Permana
    Citation: BMC Pediatrics 2022 22:663
  4. Although there has been promising progress in the reduction of child mortality from ARI, the magnitude is high yet, especially in East Africa. Since mothers/guardians decide upon the type and frequency of heal...

    Authors: Dagmawi Chilot, Kegnie Shitu, Yibeltal Yismaw Gela, Mihret Getnet, Bezawit Mulat, Mengistie Diress and Daniel Gashaneh Belay
    Citation: BMC Pediatrics 2022 22:662
  5. Iron deficiency is one of the most important factors of anemia which is caused by poor iron intake. In addition, children need more iron because of their rapid growth. On the other side, daily intake of iron i...

    Authors: Daniel Gashaneh Belay, Melaku Hunie Asratie, Anteneh Ayelign Kibret, Kegnie Shitu, Dawit Tefera Fentie, Yalelet Fentaw Shiferaw and Baye Tsegaye Amlak
    Citation: BMC Pediatrics 2022 22:661
  6. Having infants sleep with their parents and sleeping face down or on their sides are the two most proximate and modifiable risk factors for sudden infant death syndrome (SIDS). Little is known about the burden...

    Authors: Godwin K. Osei-Poku, Lawrence Mwananyanda, Patricia A. Elliot, William B. MacLeod, Somwe Wa Somwe, Rachel C. Pieciak and Christopher J. Gill
    Citation: BMC Pediatrics 2022 22:660
  7. HIV testing is a crucial starting point for prevention, early diagnosis, and treatment of HIV. Sub-Saharan Africa has the highest global HIV/AIDS prevalence and mortality, yet HIV testing remains sub-optimal. ...

    Authors: Mi Sook Jung, Nondumiso Satiso Dlamini, Xirong Cui and Kyeongin Cha
    Citation: BMC Pediatrics 2022 22:659
  8. To detect differentially expressed genes in patients with neonatal necrotizing enterocolitis (NEC) by bioinformatics methods and to provide new ideas and research directions for the prevention, early diagnosis...

    Authors: Xuexiu Liu, Xianhong Zhang, Luquan Li, Jianhui Wang, Yanhan Chen and Liping Wu
    Citation: BMC Pediatrics 2022 22:658
  9. Parents of children who have a congenital anomaly can experience significant worry about their child’s health. Access to clear, helpful, and trustworthy information can provide a valuable source of support. In...

    Authors: Elena Marcus, Anna Latos-Bielenska, Anna Jamry-Dziurla, Ingeborg BariÅ¡ić, Clara Cavero-Carbonell, Elly Den Hond, Ester Garne, Lucas Genard, Ana João Santos, LRenée Lutke, Carlos Matias Dias, Christina Neergaard Pedersen, Amanda J. Neville, Annika Niemann, Ljubica Odak, Anna Pierini…
    Citation: BMC Pediatrics 2022 22:657
  10. The purpose of this study, conducted within the framework of the project entitled ‘Let’s get the kids moving’, was to determine the associations between children’s longitudinal and transverse foot arch and the...

    Authors: Sara Górna, Katarzyna Pazdro-Zastawny, Alicja Basiak-Rasała, Mateusz Kolator, Joanna Krajewska and Tomasz Zatoński
    Citation: BMC Pediatrics 2022 22:656
  11. The Centers for Disease Control and Prevention and the American Academy of Pediatrics recommend that symptomatic children remain home and get tested to identify potential coronavirus disease 2019 (COVID-19) ca...

    Authors: Geena Y. Zhou, Nicole Y. Penwill, Grace Cheng, Prachi Singh, Ann Cheung, Minkyung Shin, Margaret Nguyen, Shalini Mittal, William Burrough, Mia-Ashley Spad, Sarah Bourne, Naomi S. Bardach and Emily R. Perito
    Citation: BMC Pediatrics 2022 22:655
  12. Hirschsprung-associated enterocolitis (HAEC), one of the most significant causes of morbidity and mortality for patients with Hirschsprung disease (HSCR), can occur before and after radical surgery. This study...

    Authors: Chuanping Xie, Jiayu Yan, Zhiyi Zhang, Wang Kai, Zengmeng Wang and Yajun Chen
    Citation: BMC Pediatrics 2022 22:654
  13. In 2018, nearly 90% of the global children living with human immunodeficiency virus (HIV) were in sub-Saharan Africa (SSA). Compared to the adult population, antiretroviral therapy (ART) coverage among childre...

    Authors: Melkamu Merid Mengesha, Mulugeta Embibel, Tesfaye Gobena, Abayneh Tunje, Degu Jerene and Inger Kristensson Hallström
    Citation: BMC Pediatrics 2022 22:653
  14. A balanced nutrition is important for children’s physical and cognitive development; yet, remains a challenge in many parts of low- and middle-income countries (LMICs). Early detection of nutritional deficienc...

    Authors: Sylvain G. Traoré, Kouadio B. Kouassi, Jean T. Coulibaly, Johanna Beckmann, Bomey C. Gba, Christin Lang, Kurt Z. Long, Daouda Dao, Markus Gerber, Nicole Probst-Hensch, Uwe Pühse, Jürg Utzinger and Bassirou Bonfoh
    Citation: BMC Pediatrics 2022 22:651
  15. Primary generalized glucocorticoid hypersensitivity (PGGH) is a very rare disease caused by terminal organ hypersensitivity to glucocorticoids for which the aetiology is unknown. The incidence of PGGH is extre...

    Authors: Xiu Zhao, Zhongwei Xu, Huiping Su, Rongfei Zheng, Min Zhan, Yuge Huang and Zhe Su
    Citation: BMC Pediatrics 2022 22:650
  16. Teaching Basic Life Support (BLS) in schools is a key initiative to improve the survival rates after out-of-hospital cardiac arrest. Low-cost training materials can reach a wider population. Our aim was to com...

    Authors: Anita Kovács, Henrietta Bánfai-Csonka, József Betlehem, Luca Anna Ferkai, Krisztina Deutsch, János Musch and Bálint Bánfai
    Citation: BMC Pediatrics 2022 22:648
  17. Duplication of the common bile duct (CBD) is extremely rare among the anatomical variations in the biliary tract system, which presents a septum within the CBD or an accessory CBD. In our study, we report a ra...

    Authors: Huixue Sheng, Guiling Chen, Ming Yang and Hongmei Guan
    Citation: BMC Pediatrics 2022 22:647
  18. Ear, Nose and Throat (ENT) primary contact models of care use audiologists as the first triage point for children referred to ENT for middle ear and hearing concerns; and have shown reduced waiting time, impro...

    Authors: Jennifer Eakin, Simone Michael, Christopher Payten, Tamsin Smith, Vicky Stewart, Elle Noonan and Kelly A. Weir
    Citation: BMC Pediatrics 2022 22:646
  19. Given the possible effect of maternal anxiety on the severity of colic pain in infants, this study aimed to investigate the effects of behavioral therapy counseling on infantile colic (primary outcome), matern...

    Authors: Reihaneh Montazeri, Shirin Hasanpour, Mojgan. Mirghafourvand, Manizheh Mostafa Gharehbaghi, Mohammad Mehdi Ghods Tehrani and Shiva Mohajjel Rezaei
    Citation: BMC Pediatrics 2022 22:645
  20. With the rapid development of deep learning algorithms and the rapid improvement of computer hardware in the past few years, AI-assisted diagnosis software for bone age has achieved good diagnostic performance...

    Authors: Kai Zhao, Shuai Ma, Zhaonan Sun, Xiang Liu, Ying Zhu, Yufeng Xu and Xiaoying Wang
    Citation: BMC Pediatrics 2022 22:644
  21. Infection is one of the most frequent causes of morbidity and mortality in diabetic patients. Some microorganisms become more virulent in a high glucose concentration. Diabetics are more likely to have asympto...

    Authors: Gihan M. Bebars, Asmaa N. Mostafa, Hend M. Moness and Reem A. Abdel Aziz
    Citation: BMC Pediatrics 2022 22:643
  22. Goiter is a common presenting sign of various thyroid diseases in children. Thyroid nodules are clinically and/or radiologically significant findings due to their high malignancy rate. The ultrasound (US) char...

    Authors: Fahad Al Juraibah, Khalid Al Noaim, Abdulaziz AlDbas, Ahmed AlMuallimi, Omar AlOtaibi, Mozon AlShareef, Alanoud AlSuhibani, Ahmed AlZaharani, Mohammed AlDubayee and Amir Babiker
    Citation: BMC Pediatrics 2022 22:642
  23. Primary intussusception in children is a common acute abdominal disease. The cause of this disease is still not fully understood. Many articles have reported that children with intussusception are often accomp...

    Authors: Qingtao Yan, Liandi Xu, Jun Chao, Zemin Zhang and Hui Wang
    Citation: BMC Pediatrics 2022 22:641
  24. Necrotizing enterocolitis (NEC) is an inflammatory bowel disease in preterm neonates with high morbidity and mortality. The only treatment available is supportive with broad-spectrum antibiotics and gastrointe...

    Authors: Björn Andersson, Laszlo Markasz, Hamid Mobini-Far and Helene Engstrand Lilja
    Citation: BMC Pediatrics 2022 22:640
  25. COPA syndrome is a rare hereditary inflammatory disease caused by mutations in the gene encoding the coatomer protein subunit alpha, causing excessive production of type I interferon.

    Authors: Pietro Basile, Giulia Gortani, Andrea Taddio, Serena Pastore, Federica Corona, Alessandra Tesser, Egidio Barbi and Alberto Tommasini
    Citation: BMC Pediatrics 2022 22:639
  26. Although most cases of childhood cancer are unlikely to be prevented, by today’s standards, most children with cancer can now be cured. However, disparities about survival exist among countries; in Mexico, the...

    Authors: Leslie V. Uribe-Ortiz, Bárbara M. Garza-Ornelas, Ana C. Vázquez-Fernández, Fabiola Castorena-Torres and Julieta Rodríguez-De-Ita
    Citation: BMC Pediatrics 2022 22:638
  27. In respiratory distress syndrome, many neonatology centers worldwide perform minimal invasive surfactant application in premature infants, using small-diameter catheters for endotracheal intubation and surfact...

    Authors: Lorenz Auer-Hackenberg, Johannes Brandner, Edda Hofstätter, Patricia Stroicz, Tobias Hager, Anna Eichhorn, Sebastian Schütz, Raphael Feldner and Martin Wald
    Citation: BMC Pediatrics 2022 22:637
  28. This case–control study aimed to compare lead (Pb), cadmium (Cd), and arsenic (As) levels in neonates with respiratory distress syndrome (NRDS) with those levels in normal neonates and tested their association...

    Authors: Khalid M. Mohany, Osama Mahmoud El-Asheer, Yaser F. Abdel Raheem, Ahmed Abd-Elrasoul sayed and Mona Abd El-Hamid Hassan El-Baz
    Citation: BMC Pediatrics 2022 22:635
  29. In recent years, obesity and vitamin D deficiency are more prevalent among adolescents. Improving our knowledge of the link between vitamin D and visceral adipose tissue (VAT) is essential for the health of ad...

    Authors: Yan-feng Li, Xiao Zheng, Wen-lan Gao, Feng Tao and Yi Chen
    Citation: BMC Pediatrics 2022 22:634
  30. Acute infections are a common reason for children to consult primary care. Serious infections are rare but differentiating them from self-limiting illnesses remains challenging. This can lead to inappropriate ...

    Authors: Liselore De Rop, Tine De Burghgraeve, An De Sutter, Frank Buntinx and Jan Y Verbakel
    Citation: BMC Pediatrics 2022 22:633
  31. Spinal muscular atrophy (5q-SMA; SMA), a genetic neuromuscular condition affecting spinal motor neurons, is caused by defects in both copies of the SMN1 gene that produces survival motor neuron (SMN) protein. The...

    Authors: John W. Day, Kelly Howell, Amy Place, Kimberly Long, Jose Rossello, Nathalie Kertesz and George Nomikos
    Citation: BMC Pediatrics 2022 22:632
  32. Neonatal lupus erythematosus is a rare multisystem autoimmune disorder that predominantly involves the heart with congenital heart block but can involve other organs including the liver. The disease results fr...

    Authors: Ammar Abdulaziz Khayat and Amani Jaboor Alkhaldi
    Citation: BMC Pediatrics 2022 22:630
  33. As sequencing technology has advanced in recent years, a series of synapse-related gene variants have been reported to be associated with autism spectrum disorders (ASDs). The α-amino-3-hydroxy-5-methyl-4-isox...

    Authors: Qianyun Cai, Zhongjie Zhou, Rong Luo, Tao Yu, Dengfeng Li, Fan Yang and Zuozhen Yang
    Citation: BMC Pediatrics 2022 22:629
  34. Very low birth weight (VLBW: ≤1500 g) is associated with multiple short and long-term complications. This study aimed to examine outcomes and predictors of functioning, mental health, and health-related qualit...

    Authors: Arnt Erik Karlsen Wollum, Elias Kjølseth Berdal, Johanne Marie Iversen, Marit S. Indredavik and Kari Anne I. Evensen
    Citation: BMC Pediatrics 2022 22:628
  35. Deficiencies in oral motor function and feeding skills are common in children with cerebral palsy (CP). Oral motor therapy is a useful method to improve oral motor function and feeding skills. Oral motor facil...

    Authors: Kyoung-chul Min, Sang-min Seo and Hee-soon Woo
    Citation: BMC Pediatrics 2022 22:626
  36. We previously reported that 1-year-old infants born to mothers who regularly consumed fermented food during pregnancy had a lower risk of sleep deprivation. However, it is not known if these positive effects a...

    Authors: Mariko Inoue, Kenta Matsumura, Narumi Sugimori, Kei Hamazaki, Akiko Tsuchida and Hidekuni Inadera
    Citation: BMC Pediatrics 2022 22:624
  37. Very preterm infants often require mechanical ventilation. However, objective criteria to predict the outcomes of extubation in very premature neonates remain lacking. The aim of this study was to investigate ...

    Authors: Zhe Li, Jiang Xue, Xin-Yuan Guo, Fang Wang, Xue Zhang, Qi Li, Jing-Liang Tang, Juan Ji and Guang-Jun Du
    Citation: BMC Pediatrics 2022 22:627
  38. Idiopathic connective tissue disease juvenile dermatomyositis (JDM) is characterised by inflammatory myositis and distinctive skin abnormalities. Only a few cases of Dermatomyositis (DM) owing to chemotherapy ...

    Authors: Keta Vagha, Chitturi Venkata Sai Akhil, Spandana Madirala, Ashish Varma, Mahaveer Lakra and Jayant Vagha
    Citation: BMC Pediatrics 2022 22:623
  39. Neonatal hemochromatosis causes acute liver failure during the neonatal period, mostly due to gestational alloimmune liver disease (GALD). Thalassemia causes hemolytic anemia and ineffective erythropoiesis due...

    Authors: Mitsuru Tsuge, Aya Kodera, Hiromi Sumitomo, Tooru Araki, Ryuichi Yoshida, Kazuya Yasui, Hiroki Sato, Yosuke Washio, Kana Washio, Kenji Shigehara, Masato Yashiro, Takahito Yagi and Hirokazu Tsukahara
    Citation: BMC Pediatrics 2022 22:622
  40. Childhood vaccination rates in Armenia are high. However, anecdotal evidence suggests that some health workers may advise against vaccination. The extent and reasons behind this are unknown. This study used th...

    Authors: Cath Jackson, Siff Malue Nielsen, Brigida Simonyan, Marine Kirakosyan, Marine Hovhannisyan, Gayane Sahakyan and Katrine Bach Habersaat
    Citation: BMC Pediatrics 2022 22:620
  41. Electroencephalogram and neuroimaging in pediatric patients with new-onset afebrile seizures are performed to detect any underlying pathological severe condition that may require emergent neuro-intervention an...

    Authors: Noman Ali, Sohaib Haider, Syed Mustahsan, Murk Shaikh, Ahmed Raheem, Salman Muhammad Soomar and Shahan Waheed
    Citation: BMC Pediatrics 2022 22:619
  42. Multiple ear infections is causing hearing impairment among children all over the world and the health and social consequences track into early adolescence and later in life, if not treated. The monitoring of ...

    Authors: Christina Schnohr, Jakob Schmidt Jensen, Cecilie Friis Skovsen, Preben Homøe, Birgit Niclasen and Ramon Gordon Jensen
    Citation: BMC Pediatrics 2022 22:618

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