Skip to main content
Fig. 5 | BMC Pediatrics

Fig. 5

From: Semaphorin 7A promotes endothelial permeability and inflammation via plexin C1 and integrin β1 in Kawasaki disease

Fig. 5

Sema7A induces HCAEC hyperpermeability via both plexin C1 and integrin β1. a Induction of HCAEC monolayer permeability by medium containing 20% untreated KD sera or 20% sSema7A-neutralized KD sera. b HCAEC permeability assay by rhSema7A stimulation upon blockade of plexin C1 and integrin β1, respectively. Data are expressed as M ± SEM from three experiments. *P < 0.05; **P < 0.01; ***P < 0.001. Sema7A: Semaphorin 7A; FITC: fluorescein isothiocyanate; KDS: sera from KD patients (medium containing 20% KD sera (pooled from 10 KD patients) ); KD: Kawasaki disease

Back to article page

BMC Pediatrics

ISSN: 1471-2431

Contact us