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Table 5 Predictors of corticosteroid use at 1 year after IBD diagnosis (n = 62)

From: Multicenter registry of pediatric inflammatory bowel disease from a developing country

Characteristics at diagnosis

Univariate analysis

Multivariate analysis

OR (95%Cl)

P

OR (95%Cl)

P

Age

1.01 (0.90, 1.13)

0.87

  

Female

2.51 (0.89, 7.08)

0.08

3.08 (1.02, 9.33)

0.046

Duration from onset to diagnosis

0.99 (0.95, 1.02)

0.51

  

Type of IBD (Crohn’s disease vs. ulcerative colitis)

2.50 (0.89, 7.14)

0.08

3.03 (1.02, 9.09)

0.046

Abdominal pain

0.74 (0.27, 2.06)

0.57

  

Diarrhea

1.06 (0.36, 3.13)

0.92

  

Weight loss/failure to thrive

2.19 (0.79, 6.05)

0.13

  

Anemia

0.65 (0.21, 2.05)

0.47

  

Thrombocytosis

1.20 (0.42, 3.41)

0.73

  

Hypoalbuminemia

1.91 (0.70, 5.25)

0.21

  

Erythrocyte sedimentation rate > 20 mm/h

1.29 (0.26, 6.29)

0.76

  

C-reactive protein > 5 mg/L

2.10 (0.67, 6.65)

0.21

  

Moderate to severe disease (defined by disease activity score*)

1.37 (0.49, 3.86)

0.55

  
  1. Abbreviations: IBD, inflammatory bowel disease. * Disease severity defined by pediatric Crohn’s disease activity index (PCDAI) score for Crohn’s disease and pediatric ulcerative colitis activity index (PUCAI) for ulcerative colitis. Moderate to severe disease were defined when PCDAI > 30 for Crohn’s disease and PUCAI ≥ 35 for ulcerative colitis