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Table 3 Treatment during the first 3 months of IBD diagnosis and at 1 year after the diagnosis

From: Multicenter registry of pediatric inflammatory bowel disease from a developing country

Medications (%)

At diagnosis

(n = 72)

CD

(n = 35)

UC

(n = 36)

P value

(CD vs. UC)

1 year after diagnosis

(n = 62)

CD

(n = 28)

UC

(n = 34)

P value

(CD vs. UC)

Corticosteroids

64.8

82.9

47.2

0.002

43.7

51.4

36.1

0.19

5-aminosalicylic acid

64.8

37.1

91.7

< 0.001

47.9

22.9

72.2

< 0.001

Immunomodulators/calcineurin inhibitors*

55.6

82.6

30.6

< 0.001

51.6

78.6

29.4

< 0.001

Infliximab

11.3

17.1

5.6

0.12

15.5

17.1

13.9

0.71

Others, n

        

Adalimumab

 

1

   

1

  

Budesonide

     

1

1**

 

Metronidazole

 

2

      

Ciprofloxacin

 

2

      

Vancomycin

 

1

2

   

2

 
  1. Abbreviations: CD, Crohn’s disease; IBD, inflammatory bowel disease; UC, ulcerative colitis. One child in this cohort was diagnosed with IBD-unclassified.
  2. *Immunomodulators/calcineurin inhibitors include azathioprine, 6-mercaptopurine, cyclosporin, and methotrexate
  3. **Budesonide was tried in one UC child with steroid-dependent who was already on azathioprine but had severe reaction to infliximab
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BMC Pediatrics

ISSN: 1471-2431

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