Table 2 Features of IBD children classified by the very early onset IBD status
From: Multicenter registry of pediatric inflammatory bowel disease from a developing country
Characteristics | Very early onset IBD | P value | |
|---|---|---|---|
Yes, n = 27 | No, n = 44 | ||
CD vs. UC | 14:13 | 21:23 | 0.74 |
Female, % | 25.9 | 47.7 | 0.07 |
Male to female ratio | 2.86:1 | 1.10:1 | |
Duration from onset to diagnosis, mean (SD), months | 7.7 (8.0) | 10.8 (15.9) | 0.34 |
Presenting symptoms and signs, % | |||
Diarrhea Bloody stools Fever Weight loss/failure to thrive | 66.7 81.5 22.2 55.6 | 70.5 65.9 31.8 47.7 | 0.74 0.16 0.38 0.52 |
Laboratory investigations | |||
Anemia for age, % Thrombocytosis (> 450, 000/cu mm), % C-reactive protein ≥ 5 mg/L, % Hypoalbuminemia (< 35 g/L), % | 81.5 63.0 74.1 44.4 | 70.5 68.2 75.0 52.3 | 0.30 0.65 0.93 0.52 |
Moderate to severe disease (defined by disease activity score*) at presentation, % | 70.4 | 56.8 | 0.25 |
Corticosteroid use during the first 3 months of diagnosis Early immunomodulator use | 59.3 51.8 | 68.1 56.8 | 0.45 0.68 |