Table 1 Features of IBD children compared between Crohn’s disease vs. ulcerative colitis

Age at diagnosis, mean (SD), years

 Early onset IBD (diagnosed < 10 years), %

 Very early onset IBD (diagnosed < 6 years), %

7.9 (4.1)

62.5

38.0

8.1 (4.6)

57.1

40.0

7.8 (3.5)

66.7

36.1

0.76

0.41

0.77

Female, %

39.4

31.4

47.2

0.17

 Male to female ratio

1.54:1

2.18:1

1.12:1

Duration from onset to diagnosis, mean (SD), months

9.5 (13.4)

6.9 (10.3)

12.5 (15.6)

0.08

Presenting symptoms and signs, %

 Abdominal pain

 Diarrhea

 Bloody stools

 Fever

 Pallor

 Weight loss/failure to thrive

 Perianal lesions (large perianal skin tags, fistula, abscess)

43.7

69.0

71.8

28.2

38.0

50.7

-

45.7

62.9

51.4

42.3

34.3

68.6

31.4

41.7

75.0

91.7

13.9

41.7

33.3

N/A

0.73

0.27

< 0.001

0.007

0.52

0.003

N/A

Laboratory investigations

 Hemoglobin (g/dL), mean (SD)

 Anemia for age, %

 Platelet (x10³/cu mm), mean (SD)

 Thrombocytosis (> 450, 000/cu mm), %

 Erythrocyte sedimentation rate (mm/h), mean (SD)

 ≥ 20 mm/h, %

 C-reactive protein (mg/L), mean (SD)

 ≥5 mg/L, %

 Albumin (g/L), mean (SD)

 Hypoalbuminemia (< 35 g/L), %

10.1 (3.4)

74.7

514 (231)

66.2

49.5 (24.5)

87.3

36.9 (68.6)

74.7

33.1 (7.7)

49.3

9.7 (1.8)

74.3

526 (235)

68.6

51.1 (24.8)

88.6

47.3 (45.1)

94.3

30.4 (7.4)

62.9

10.5 (4.5)

75.0

506 (233)

63.9

47.8 (25.1)

86.1

28,0 (85.6)

55.6

35.5 (7.2)

36.1

0.33

0.95

0.72

0.68

0.58

0.76

0.24

< 0.001

0.004

0.02

Moderate to severe disease (defined by disease activity score^†) at presentation, %

62.0

68.6

55.6

0.26