From: Seizures in febrile children with SARS-CoV-2 infection: clinical features, short-term follow-up
Variable | COVID-19 positive group | COVID-19 negative group | P |
---|---|---|---|
N | 182 | 117 | |
Male | 107(58.8%) | 67(57.3%) | 0.794 |
Age (years) | 2.3(1.3–3.8) | 2.1(1.2–3.5) | 0.239 |
≤1 years | 25(13.7%) | 17(14.5%) | 0.847 |
1–5 years | 130(71.4%) | 85(72.6%) | 0.819 |
≥5years | 27(14.8%) | 15(12.8%) | 0.625 |
Time from fever onset to seizure | |||
<24 hours | 163(89.6%) | 101(86.3%) | 0.396 |
≥24hours | 19(10.4%) | 16(13.7%) | 0.396 |
Seizure types | |||
Generalized seizures | 173(95.1%) | 110(94.0%) | 0.697 |
Partial seizures | 9(4.9%) | 7(6.0%) | 0.697 |
Seizure duration ≥ 15min | 34(18.7%) | 6(5.1%) | 0.001 |
Status epilepticus | 28(15.4%) | 6(5.1%) | 0.006 |
History of convulsions | 82(45.1%) | 43(36.8%) | 0.155 |
Family history of convulsions | 42(23.1%) | 29(24.8%) | 0.736 |
Seizure ≥ 2 time | 99(54.4%) | 48(41.0%) | 0.024 |
Peak body temperature, ℃ | 39.5(39.0–40.0) | 39.5(39.0–40.0) | 0.019 |
Abnormal EEG | 20/68(29.4%) | 12/88(13.6%) | 0.016 |
Simultaneous phenomenon | |||
Pharyngodynia | 10(5.5%) | 6(5.1%) | 0.891 |
Cough | 79(43.4%) | 51(43.5%) | 0.975 |
Vomiting | 52(28.6%) | 20(17.1%) | 0.023 |
Diarrhoea | 9(4.9%) | 8(6.8%) | 0.490 |
Dizziness/Headache | 8(4.4%) | 2(1.7%) | 0.352 |
Labiratory results | |||
WBC(*109/L) | 5.9(4.7–7.6) | 8.7(6.3–12.8) | < 0.001 |
HB(g/dl) | 12.1(11.6–12.7) | 12.1(11.4–12.8) | 0.295 |
PLT(*109/L) | 212(183–258) | 239(205–309) | < 0.001 |
CRP(mg/L) | 5.2(1.8–11.2) | 9.0(2.8–30.7) | < 0.001 |