Skip to main content

Table 1 Basic information of included studies

From: Can low-dose intravenous immunoglobulin be an alternative to high-dose intravenous immunoglobulin in the treatment of children with newly diagnosed immune thrombocytopenia: a systematic review and meta-analysis

Study ID

First

author

Year of publication

Study

design

Sample size(n)

Follow-up period

Outcomes

LD-IVIg

HD-IVIg

1

Bao H [26]

2017

RCT

44

44

3 months

ER; DR; AR

2

He WD [27]

2017

RCT

48

48

3 months

ER DR; AR

Time of PC starting to rise;

Time of PC rising to normal;

Time of achieving hemostasis

3

Hou ZH [35]

2021

RCT

58

58

Not reported

ER

4

Ji LJ [29]

2022

RCT

46

46

Not reported

ER; AR

Time of PC rising to normal

Time of achieving hemostasis

5

Luo F [42]

2017

RCT

45

45

Not reported

ER

Time of PC starting to rise;

Time of achieving hemostasis

6

Su BX [44]

2016

RCT

38

40

3 months

ER; DR; AR

Time of PC starting to rise;

Time of PC rising to normal;

Time of achieving hemostasis

7

Qin HZ [38]

2015

RCT

40

40

3 months

ER; DR; AR

Time of PC starting to rise;

Time of PC rising to normal;

Time of achieving hemostasis

8

Yang YX [47]

2019

RCT

34

33

3 months

ER; DR; AR

Time of achieving hemostasis

9

Yu ZJ [48]

2018

RCT

60

60

3 months

ER; DR

Time of PC starting to rise;

Time of PC rising to normal;

Time of achieving hemostasis

10

Zhu W [50]

2014

RCT

65

65

Not reported

ER; AR

11

Zhao SL [49]

2018

RCT

17

17

6 months

ER; DR; AR

Time of PC starting to rise;

Time of PC rising to normal

Time of achieving hemostasis

12

Feng L [30]

2019

RCT

34

34

3 months

ER; DR; AR

Time of PC starting to rise;

Time of PC rising to normal

13

He WH [34]

2019

RCT

31

31

3 months

ER; DR

Time of PC starting to rise;

Time of PC rising to normal

14

Shi L [43]

2019

RCT

32

32

Not reported

ER; AR

Time of PC rising to normal;

Time of achieving hemostasis

15

Liang CJ [37]

2017

RCT

28

26

Not reported

ER; AR

Time of PC rising to normal;

Time of achieving hemostasis

16

Tan YF [39]

2016

RCT

28

28

3 months

ER; DR

Time of PC starting to rise;

Time of PC rising to normal

17

Liu LK [40]

2003

RCT

45

45

Not reported

ER

18

Yang B [46]

2013

RCT

55

55

Not reported

ER; AR

Time of PC rising to normal;

Time of achieving hemostasis

19

Wang Y [45]

2022

RCT

19

19

Not reported

ER

20

Jin Y [36]

2020

RCT

25

25

Not reported

ER

21

Yang Y [32]

2022

RCT

51

51

Not reported

ER

Time of PC starting to rise;

Time of PC rising to normal;

Time of achieving hemostasis

22

Hu XL [33]

2018

RCT

50

50

3 months

ER; DR

23

Gong CX [31]

2016

Cohort study

30

33

18 months

ER; DR

24

Liu YY [41]

2008

Cohort study

27

32

Not reported

ER

25

Huang HY [28]

2022

Cohort study

41

41

Not reported

ER; AR

  1. Abbreviation RCT: randomized controlled trial; LD-IVIg: low-dose intravenous immunoglobulin; HD-IVIg: high-dose intravenous immunoglobulin; ER: effective rate; DR: durable remission rate; AR: adverse reaction rate; PC: platelet count