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Table 1 Demographics and characteristics of infants in the baseline and postintervention groups

From: Antibiotic use in infants at risk of early-onset sepsis: results from a unicentric retrospective cohort study

 

Study period

 

Characteristic

Baseline

n = 71

Postintervention

n = 66

pvalue

Birthweight, g, mean (SD)

3494 (489)

3369 (451)

0.23

Gestational age, weeks, mean (SD)

39.5 (1.1)

39.7 (1.3)

0.14

Cesarean delivery

25 (35.2%)

26 (39.4%)

0.34

Apgar, 5 min

0–3

0 (0%)

2 (3%)

0.01

4–6

6 (8.5%)

15 (22.7%)

7–10

65 (91.6%)

49 (74.2%)

GBS status

Positive

15 (21%)

18 (27.3%)

0.57

Negative

50 (70.4%)

45 (68.2%)

Unknown

6 (8.5%)

3 (4.5%)

Maternal temperature > 38ºC

30 (42.3%)

28 (42.4%)

0.98

ROM > 18 h

21 (29.6%)

13 (19.7%)

0.18

Intrapartum antibiotic therapy

38 (53.5%)

45 (68.2%)

0.08

CRP, mg/dL

Onset, median (IQR)

0.6 (0.1–2.2)

1.41 (0.04–3.60)

0.39

Highest, median (IQR)

3.7 (2.9–6.7)

3.5 (1.8–5.7)

0.09

  1. SD, standard deviation; IQR, interquartile range; GBS, group B Streptococcus; ROM, rupture of membranes; CRP, C-reactive protein.