Table 3 Long-term renal follow-up after completion of treatment with ifosfamide
n | Median (min-max) | Number of abnormal values (%) | |
|---|---|---|---|
General parameters | |||
Systolic BP percentile (%, N < 95th percentile) | 13 | 62 (1–93) | 0 |
Diastolic BP percentile (%, N < 95th percentile) | 13 | 78 (10–95) | 0 |
Glomerular parameters | |||
mGFR (ml/min/1.73m2, N > 90) | 13 | 87 (55–111) | 7 (54%) |
Plasma creatinine (µmol/L, N depending of age and sex) | 13 | 69 (45–102) | 0 |
Urine albumin/creatinine (mg/mmol, N < 3) | 11 | 1.4 (0.6–12.0) | 3 (27%) |
Tubular parameters | |||
Plasma sodium (mmol/l, N 136–145) | 13 | 139 (137–146) | 0 |
Plasma potassium (mmol/l, N 3.5–4.8) | 12 | 4.0 (3.6–4.5) | 0 |
Plasma bicarbonate (mmol/l, N 22–29) | 12 | 24.2 (21.0–30.0) | 0 |
Plasma calcium (mmol/l, N 2.10–2.55) | 13 | 2.4 (2.2–2.7) | 0 |
Plasma magnesium (mmol/l, N 0.70–0.91) | 13 | 0.9 (0.8–86.0) | 0 |
Plasma phosphate (mmol/l, N depending of age) | 12 | 1.2 (0.9–1.9) | 0 |
Fractional excretion of phosphate (%, N < 20) | 12 | 10.2 (2.7–25.9) | 1 (8%) |
TmP/GFR (mmol/l, N > 0.8 mmol/L) | 12 | 1.1 (0.8–1.5) | 0 |
Plasma uric acid (µmol/L, N depending of age and sex) | 13 | 213 (129–333) | 4 (31%) |
Fractional excretion of uric acid (%, N < 11.26) | 13 | 8.6 (3.2–16.0) | 3 (23%) |
Fractional excretion of glucose (%, N < 0.1) | 11 | 0.1 (0-0.2) | 1 (9%) |
Urine calcium/creatinine (mmol/mmol, N < 0.7) | 13 | 0.3 (0.1–0.7) | 0 |
Urine β2-microglobulin/creatinine (mg/mol, N < 40.7) | 9 | 36.0 (2.0-299.0) | 4 (44%) |
Urine osmolality (mOsm/kg, N > 700) | 12 | 872.5 (591.0-1024.0) | 1 (8%) |