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Table 2 Univariate and multivariate analysis of the factor associated with overall mortality of children admitted to PICU, from the time of admission to three months after discharge

From: Mortality and associated factors among children admitted to an intensive care unit in muhimbili national hospital, from the time of admission to three months after discharge: a prospective cohort study

  

Univariate analysis

Multivariate analysis

Variable

Crude HR

95% CI

P-value

Adjusted HR

95% CI

P-value

Age (Years)

      

 < 1

1.20

0.72–1.67

0.674

   

 1–5

0.95

0.63–1.45

0.820

   

 > 5

Ref

     

Admiting diagnosis

      

 Infectious

1.65

1.18–2.30

0.004

0.76

0.52–1.12

0.163

 Non Infectious

Ref

     

Type of admission

      

 Medical

2.07

1.37–3.13

0.001

   

 Surgical

Ref

     

Chronic Illness

      

 Yes

0.93

0.68–1.28

0.669

   

 No

Ref

     

Organ Dysfunction

      

  Multiple

5.71

3.35–9.73

< 0.001

5.97

3.22– 12.06

< 0.001

  Single

2.54

1.44–4.49

0.001

2.77

1.50–5.14

0.001

  None

Ref

     

Creatinine (micromol/L)

      

  Elevated

1.87

1.36–2.58

< 0.001

1.27

0.90–1.78

0.18

  Normal

Ref

     

ALT (units/L)

      

  >114

1.71

1.20–2.43

0.003

0.98

0.67–1.42

0.896

 < 114

Ref

     

Hemoglobin (g/dl)

      

 <11

1.70

1.15–2.50

0.008

1.28

0.85–1.91

0.238

 >11

Ref

     

Platelet (×109/L)

      

 <150

1.21

0.86–1.70

0.271

   

 >450

0.69

0.41–1.16

0.156

   

 150–450

Ref

     

WBC (×109/L)

      

 <4

1.25

0.45–3.44

0.668

   

 >11

1.29

0.94–1.79

0.120

   

 4–11

Ref

     
  1. ALT: Alanine aminotransferase, WBC: White blood cells, CI: Confidence interval, HR: Hazard ratio