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Table 3 Serology rates and histopathological features of patients

From: Retrospective, single-center analysis of autoimmune hepatitis in Jordanian children: clinical features, treatments, and outcomes

Serology markers

Positivity rates

ANA

10 (62.5%)

AMA

4 out of 13 (30.8%)

ASMA

9 (56.3%)

Anti-LKM

0

Hypergammaglobulinemia

9 out of 12 (75.0%)

Histological features

 interface hepatitis

13 (81.3%)

 Lymphocytic infiltrates

10 (62.5)

 Lymphoplasmocytic portal infiltrates extending into lobule

7 (43.8%)

 hepatocyte rosette formation

2 (12.5%)

- Degree of fibrosis (Ishak Method) a (0–6):

 - 0

- 5 (31.3%)

 - 1

- 3 (18.8%)

 - 2

- 1 (6.3%)

 - 3

- 3 (18.8%)

 - 4

- 2 (12.5%)

 - 5/6

- 2 (12.5%)

  1. a Ishak K, Baptista A, Bianchi L, et al. Histological grading and staging of chronic hepatitis. J Hepatol. 1995;22(6):696–699