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Table 3 Laboratory data of the included children with T1DM

From: Prevalence of celiac-related antibodies and its impact on metabolic control in Egyptian children with type 1 diabetes mellitus

Variable

Patients

(N = 200)

Patients’ subgroups

Patients with positive tests (n = 11)

Patients with negative tests (n = 189)

p-value

Hemoglobin level (Mean ± SD)

12.65 ± 1.12

11.69 ± 1.42

12.71 ± 1.07

0.003*

Cases with anemia (N. %)

21 (10.5%)

5 (45.5%)

16 (8.5%)

0.0001*

HCT (Mean ± SD)

39.11 ± 3.25

37.46 ± 4.7

39.2 ± 3.14

0.085

MCH (Mean ± SD)

33.4 ± 4.57

30.52 ± 4.06

33.56 ± 4.55

0.031*

MCV (Mean ± SD)

78.62 ± 3.9

77.66 ± 3.17

78.68 ± 3.94

0.404

WBCs (Mean ± SD)

6.27 ± 1.55

6.24 ± 1.65

6.27 ± 1.55

0.942

Platelets (Mean ± SD)

297.34 ± 81.76

316.82 ± 125.47

296.21 ± 78.84

0.418

RBG (Mean ± SD)

242.08 ± 74.18

282.91 ± 124.75

239.7 ± 69.95

0.060

Hb A1c (Mean ± SD)

9.29 ± 1.64

10.74 ± 2.01

9.21 ± 1.58

0.002*

Glycemic control (N. %)

Good control (HbA1c < 7.5%)

Poor control (HbA1c ≥ 7.5%)

68(34%)

132(66%)

2(18.18%)

9(81.82%)

66 (34.92%)

123(65.08%)

0.255

tTG-IgA antibodies IU/ml

Median (IQ range)

3.0 (1.85–4.3)

230.6(48.7–260.2)

2.8(1.7–4)

< 0.001*

tTG-IgG antibodies IU/ml

Median (IQ range)

4(2.9–5.7)

38(15–59.7)

3.8(2.65–5.3)

< 0.001*

  1. -P-value between patients with positive tests and patients with negative tests. *Statistically significant predictor (p < 0.05). - HCT: Hematocrit - MCH: Mean corpuscular Hemoglobin- MCV: Mean corpuscular volume – WBCs: White blood cells- RBG: Random blood glucose- Hb A1c: Hemoglobin A1C- tTG-IgA antibodies: anti-Tissue transglutaminase IgA antibody - tTG-IgG antibodies: anti-tissue transglutaminase IgG Antibody