Table 2 Genotype polymorphism and minor allele frequency of TMPRSS6 gene among the studied groups
From: The association of TMPRSS6 gene polymorphism with iron status in Egyptian children (a pilot study)
Genotype polymorphism No (%) | Group 1 (Control) N = 40 | Group 2 (ID) N = 44 | Group 3 (IDA) N = 76 | P value |
|---|---|---|---|---|
Polymorphism of rs4820268 | ||||
 AA homozygote | 11 (27.5%) | 16 (36.4%) | 24 (31.6) | 0.7 |
 AG heterozygote | 20 (50%) | 20 (45.5%) | 40 (52.6%) | 0.8 |
 GG homozygote | 9 (22.5%) | 8 (18.1%) | 12 ((15.8) | 0.8 |
Polymorphism of rs855791 | ||||
 AA homozygote | 10 (25%) | 4 (9.15) | 8 (10.5%) | 0.06 |
 AG heterozygote | 28 (70%) | 40 (90.9%) | 64 (84.2%) | P1 = 0.02 P2 = 0.1 P3 = 0.001 |
 GG homozygote | 2 (5%) | 0 (0%) | 4 (5.3%) | 0.3 |
Polymorphism of rs11704654 | ||||
 CC homozygote | 24 (63.2%) | 26 (59.1%) | 54 (71.1%) | 0.3 |
 CT heterozygote | 16 (36.8%) | 18 (40.9%) | 22 (28.9%) | 0.3 |
Minor Allele Frequency (MAF) | ||||
 rs4820268 (G) | 38 (47.5%) | 36 (40.9%) | 64 (42.1%) | 0.6 |
 rs855791 (G) | 32 (40%) | 40 (45.5%) | 72 (48.4%) | 0.5 |
 rs11704654 (T) | 16 (20%) | 18 (20.4%) | 22 (14.5%) | 0.4 |