Table 1 Orofacial clefts prevalence and disability-adjusted life years in 1990 and 2019, with estimated annual percentage change

Global

Prevalence

Male

17.1 (14.0 to 20.9)

61.37 (50.01 to 74.82)

24.1

(19.7 to 29.6)

62.77

(51.28 to 76.92)

0.11

(0.10 to 0.12)

< 0.001

Female

15.6

(12.7 to 19.0)

56.94

(46.44 to 69.54)

22.1

(17.9 to 27.2)

58.39

(47.59 to 71.62)

0.17

(0.16 to 0.19)

< 0.001

Both

32.7

(26.8 to 39.9)

59.14

(48.28 to 72.15)

46.2

(37.6 to 56.7)

60.60

(49.51 to 74.45)

0.14

(0.13 to 0.16)

< 0.001

DALYs

Male

6.87

(3.33 to 11.7)

21.04

(10.45 to 35.28)

2.73

(1.82 to 4.65)

7.58

(5.03 to 13.44)

-3.73

(-3.78 to -3.67)

< 0.001

Female

5.59

(3.69 to 11.1)

18.14

(12.12 to 35.68)

2.57

(1.68 to 4.25)

7.45

(4.84 to 12.73)

-3.10

(-3.16 to -3.04)

< 0.001

Both

12.5

(8.07 to 17.5)

19.63

(12.85 to 27.44)

5.30

(3.62 to 7.98)

7.51

(5.10 to 11.57)

-3.44

(-3.50 to -3.38)

< 0.001

Eastern Mediterranean Region

Prevalence

Male

2.10

(1.70 to 2.55)

102.75

(84.05 to 125.91)

3.91

(3.16 to 4.79)

102.41

(82.88 to 125.62)

-0.05

(-0.06 to -0.04)

< 0.001

Female

1.65

(1.34 to 2.02)

84.86

(68.42 to 104.79)

3.00

(2.40 to 3.68)

84.56

(67.66 to 104.01)

-0.06

(-0.07 to -0.05)

< 0.001

Both

3.75

(3.06 to 4.56)

94.14

(76.40 to 114.81)

6.91

(5.60 to 8.51)

93.84

(75.98 to 115.49)

-0.05

(-0.06 to -0.05)

< 0.001

DALYs

Male

0.386

(0.173 to 0.843)

13.62(6.86 to 26.46)

0.394

(0.239 to 0.705)

9.77

(5.98 to 17.06)

-1.16

(-1.18 to -1.15)

< 0.001

Female

0.615

(0.263 to 2.00)

20.80

(9.61 to 62.77)

0.366

(0.224 to 0.657)

9.58

(5.90 to 16.72)

-2.90

(-2.95 to -2.86)

< 0.001

Both

1.00

(0.484 to 2.27)

17.12

(8.99 to 36.13)

0.760

(0.486 to 1.24)

9.68

(6.23 to 15.47)

-2.10

(-2.13 to -2.07)

< 0.001