Univariate | Multivariate | |||
---|---|---|---|---|
Variables | Risk Ratio | P value | Risk Ratio | P value |
Country | ||||
India | Ref | Ref | ||
Tanzania | 0.62 (0.40, 0.94) | 0.02 | 0.67 (0.45, 1.01) | 0.06 |
Maternal age > 25 years | ||||
No | Ref | |||
Yes | 1.14 (0.75, 1.73)) | 0.55 | ||
Maternal education > 7 years | ||||
No | Ref | |||
Yes | 0.99 (0.65, 1.50 | 0.95 | ||
Child age, month | ||||
6- < 12 | Ref | Ref | ||
12 to < 24 | 1.86 (1.07, 3.21) | 0.03 | 1.24 (0.74, 2.07) | 0.41 |
24 to < 60 | 0.97 (0.54, 1.74) | 0.92 | 0.48 (0.27, 0.85) | 0.01 |
Child sex | ||||
Female | Ref | |||
Male | 1.01 (0.66, 1.53) | 0.97 | ||
Breast-feeding before enrolment | ||||
No | Ref | |||
Yes | 1.29 (0.84, 1.98) | 0.24 | ||
Household wealth index above median | ||||
No | Ref | |||
Yes | 1.02 (0.67, 1.55) | 0.92 | ||
Duration of diarrhoea before enrolment | ||||
< = 24 h | Ref | |||
25 to 48 h | 0.79 (0.29, 2.13) | 0.64 | ||
49 to < 72 h | 0.71 (0.23, 2.19) | 0.55 | ||
Dysentery | ||||
No | Ref | |||
Yes | 0.89 (0.28, 2.78) | 0.84 | ||
Dehydration | ||||
No | Ref | |||
Yes | 1.04 (0.15, 7.30) | 0.97 | ||
Axillary temperature > 38 °C | ||||
No | Ref | |||
Yes | 1.62 (0.61, 4.34) | 0.33 | ||
Observed respiratory rate > 40 breaths/min | ||||
No | Ref | |||
Yes | 0.77 (0.28, 2.07) | 0.60 | ||
Cough or difficulty breathing | ||||
No | Ref | |||
Yes | 1.00 (0.63, 1.59) | 1.00 | ||
Previous use of antibiotic agent | ||||
No | Ref | |||
Yes | Non-estimable due to zero | |||
Plasma zinc concentration at enrolment < 65 µg/dl | ||||
No | Ref | |||
Yes | 0.65 (0.27, 1.56) | 0.34 | ||
Weight-for-Height z-score at enrolment | 0.07 (0.04, 0.11) | < 0.001 | 0.07 (0.04, 0.11) | < 0.001 |
Duration of episode, days | ||||
< 3 | Ref | |||
3–5 | 1.04 (0.67, 1.60) | 0.87 | ||
> 5 | 0.88 (0.35, 2.19) | 0.79 | ||
Number of loose or watery stools after enrolment* | ||||
< 7 | Ref | |||
7–9 | 1.10 (0.57, 2.14) | 0.78 | ||
10–12 | 0.95 (0.55, 1.65) | 0.86 | ||
> 12 | 0.83 (0.48, 1.40) | 0.48 | ||
Dose of Zinc intervention | ||||
20 mg | Ref | |||
10 mg | 1.31 (0.81, 2.12) | 0.27 | ||
5 mg | 0.73 (0.42, 1.28) | 0.27 | ||
Improved water | ||||
No | Ref | |||
Yes | 0.64 (0.09, 4.40) | 0.62 |