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Table 6 Comparison of allele and genotype distributions and frequencies in three genetic models between case and control groups

From: Associations between UGT1A1, SLCO1B1, SLCO1B3, BLVRA and HMOX1 polymorphisms and susceptibility to neonatal severe hyperbilirubinemia in Chinese Han population

Gene

tagSNPs

Allele

Dominant model

Recessive model

Additive model

P value

OR (95%CI)

P value

OR (95%CI)

P value

OR (95%CI)

UGT1A1

rs4148323

A

0.004

2.768

(1.359–5.638)

0.013*

/

0.119

1.759

(0.860–3.598)

rs3771341

A

0.086

0.392

(0.145–1.057)

0.450*

0.343

(0.021–5.583)

0.131*

0.410

(0.144–1.165)

rs34946978

T

1.000*

1.412

(0.290–6.882)

/

/

1.000*

1.412

(0.290–6.882)

rs114982090

T

0.342*

0.958

(0.926–0.992)

/

/

0.342*

0.958

(0.926–0.992)

SLCO1B1

rs4149056

C

0.993

1.004

(0.435–2.318)

1.000*

0.993

(0.980–1.007)

0.918

0.957

(0.413–2.218)

 

rs1564370

G

0.433

1.313

(0.663–2.599)

0.720*

0.800

(0.199–3.222)

0.336

1.423

(0.692–2.926)

SLCO1B3

rs2417940

T

0.001

3.138

(1.558–6.321)

0.258*

1.020

(0.981–1.062)

0.003

2.889

(1.429–5.839)

 

rs2117032

C

0.069

1.957

(0.942–4.064)

0.996

1.002

(0.417–2.410)

0.084

0.564

(0.293–1.085)

BLVRA

rs699512

G

0.687

0.876

(0.460–1.669)

0.563*

1.343

(0.443–4.076)

0.481

1.270

(0.653–2.471)

HMOX1

rs2071747

C

0.362*

2.382

(0.518–10.944)

/

/

0.362*

2.382

(0.518–10.94)

  1. *: Fisher’s precision probability test