Table 5 Frequencies of haplotypes assigned by SNPs of UGT1A1, SLCO1B1, and SLCO1B3 genes in Case and Control Groups
Gene | SNPs constituted | Haplotypes | Frequencies | P value | OR (95%CI) | |
|---|---|---|---|---|---|---|
Case group | Control group | |||||
UGT1A1 | rs4148323,rs35350960,rs3771341 | GCA | 0.034 | 0.080 | 0.114 | 0.414 (0.159–1.079) |
GCG | 0.663 | 0.790 | 0.018 | 0.523 (0.305–0.898) | ||
ACA | 0.004 | 0.010 | 0.450 | 0.345 (0.021–5.567) | ||
ACG | 0.299 | 0.120 | 0.001 | 3.122 (1.624–6.003) | ||
rs34946978,rs114982090,rs34993780 | CCT | 0.951 | 0.980 | 0.343 | 0.399 (0.089–1.789) | |
TCT | 0.028 | 0.020 | 0.955 | 1.400 (0.292–6.706) | ||
CTT | 0.021 | / | 0.345 | / | ||
SLCO1B1 | rs4149056,rs1564370 | CC | 0.094 | 0.090 | 0.911 | 1.046 (0.474–1.373) |
TC | 0.691 | 0.730 | 0.463 | 0.827 (0.498–1.373) | ||
TG | 0.215 | 0.180 | 0.452 | 1.250 (0.698–2.238) | ||