Associations between UGT1A1, SLCO1B1, SLCO1B3, BLVRA and HMOX1 polymorphisms and susceptibility to neonatal severe hyperbilirubinemia in Chinese Han population

Table 1 Genotyping data for 12 tagSNPs genotyped from the candidate genes UGT1A1, SLCO1B1, SLCO1B3, BLVRA, and HMOX1

Gene (chromosome)	Reference SNP ID	Chromosome position	Region	MAF 1000G_CHB	MAF 1000G_EAS	Allele
UGT1A1(2)	rs4148323	234,669,144	exonic	0.192	0.138	A
	rs3771341	234,673,239	intronic	0.113	0.127	A
	rs34946978	234,676,872	exonic	0.024	0.011	T
	rs114982090	234,680,955	exonic	0.005	0.007	T
	rs35350960	234,669,619	exonic	0.007	0.014	A
	rs34993780	234,681,059	exonic	0.002	0.003	G
SLCO1B1(12)	rs4149056	21,331,549	exonic	0.127	0.123	C
	rs1564370	21,335,190	intronic	0.221	0.244	G
SLCO1B3(12)	rs2417940	21,017,875	intronic	0.173	0.195	T
	rs2117032	21,074,122	3’-flanking	0.421	0.461	C
BLVRA(7)	rs699512	43,810,764	exonic	0.310	0.317	G
HMOX1(22)	rs2071747	35,777,185	exonic	0.055	0.054	C

MAF: minor allele frequency, 1000G_CHB: Han Chinese in Beijing populations from the 1000 Genomes Project, 1000G_EAS: East Asian populations from the 1000 Genomes Project

ISSN: 1471-2431