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Fig. 2 | BMC Pediatrics

Fig. 2

From: Increased expression of NLRP3 associated with elevated levels of HMGB1 in children with febrile seizures: a case–control study

Fig. 2

Correlation between serum cytokine levels in the febrile seizure group. (a-f) Correlation between serum levels of NLRP3 and HMGB1 (a), caspase-1 and HMGB1 (b), IL-1β and HMGB1 (c), IL-1β and caspase-1 (d), IL-6 and IL-1β (e), and TNF-α and IL-1β (f) in children with febrile seizure. HMGB1 levels were significantly correlated with NLRP3, caspase-1, and IL-1β levels (all, p < 0.05, r = 0.814, r = 0.652, and r = 0.675, respectively). Caspase-1 levels were significantly correlated with IL-1β levels (p < 0.05, r = 0.589). IL-1β levels were significantly correlated with IL-6 and TNF-α levels (both, p < 0.05, r = 0.564 and 0.668, respectively)

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