Table 3 Changes of nutritional biomarker levels of infants in nHMF and cHMF group from D0 to D21

Hemoglobin, g/dL

14.3 ± 3.4

10.4 ± 2.6

12.4 ± 3.9

9.9 ± 3.2

-1.4 (-2.3, -0.5)

0.004

Albumin, g/L

32.1 ± 4.6

31.2 ± 3.1

30.8 ± 3.9

30.5 ± 3.7

-0.9 (-3.5, 0.5)

0.10

Prealbumin, mg/L

84.1 ± 28.7

83.7 ± 22.1

79.2 ± 32.3

67.8 ± 25.1

-2.4 (-11.2, 6.4)

0.59

Sodium, mmol/L

137 ± 3.5

137 ± 2.6

138 ± 3.1

138 ± 2.8

0.8 (-0.04, 1.7)

0.08

Calcium, mmol/L

2.35 ± 0.20

2.40 ± 0.16

2.32 ± 0.30

2.36 ± 0.22

-0.02 (-0.09,0.05)

0.56

Phosphorus, mmol/L

1.70 ± 0.48

2.02 ± 0.29

1.70 ± 0.42

1.98 ± 0.31

-0.06 (-0.16, 0.05)

0.28

Alkaline phosphatase, U/L

365 ± 128

312 ± 100

373 ± 155

335 ± 124

3.25(-33.3, 39.8)

0.86

BUN, mmol/L

3.18 ± 1.57

2.34 ± 0.93

3.39 ± 2.17

1.78 ± 1.18

0.6 (0.1, 1.0)

0.01

Total cholesterol, mmol/L

3.01 ± 0.89

2.90 ± 0.69

2.75 ± 0.75

2.63 ± 0.57

-0.12 (-0.32, 0.07)

0.21

Triglyceride, mmol/L

0.93 ± 0.48

0.78 ± 0.25

0.85 ± 0.47

0.90 ± 0.39

-0.06 (-0.18, 0.06)

0.34

25-hydroxyvitamin D, ng/mL

36.3 ± 13.1

40.8 ± 13.7

20.1 ± 8.2

25.7 ± 9.9

-4.09 (-18.7, 10.5)

0.58