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Table 3 Shows the summary of the trofinetide Treatment Emergent Adverse Events (TEAEs) at different doses

From: Safety and efficacy of trofinetide in Rett syndrome: a systematic review and meta-analysis of randomized controlled trials

Dose, mg

Diarrhea, %

Irritability, %

Pyrexia, %

Vomiting, %

Decreased appetite, %

200

75.0

5.8

6.7

25.8

4.2

100

12.5

6.3

0.0

12.5

0.0

70

11.1

0.0

11.1

11.1

-

50

26.7

-

0.0

6.7

6.7

35

38.9

22.2

-

0.0

-