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Table 2 Microcirculation changes and prolonged capillary refill time on admission to the PICU

From: The association between prolonged capillary refill time and microcirculation changes in children with sepsis

Microcirculation Variables

Total

N = 132

Capillary refill less than 2 sec

N = 89

Capillary refill greater than 2 sec

N = 43

P value

PBR (microns) (SD)

2.12 (0.27)

2.08 (0.27)

2.21 (0.26)

0.01a

PBR Flow Corrected (microns) (SD)

2.11 (0.51)

2.10 (0.49)

2.01 (0.55)

0.93a

Worst PBR microns (IQR)

3.26 (2.99 -3.61)

3.23 (2.97 -3.54)

3.28 (2.99–3.63)

0.61b

Capillary Density 4–6 microns (IQR)

36.8 (18.9–64.9)

39.6 (21.0–69.9)

29.5 (15.8–49.7)

0.03b

Capillary Blood Volume (%) (IQR)

63.2 (19.0–83.3)

62.4 (10.3–83.2)

66.5 (36.1–85.5)

0.13b

Syndecan-1 ng/mL (IQR)

116.8 (82.8–180.8)

115.2 (80.7–142.0)

129.7 (82.8–207.8)

0.55b

Angiopoietin-2 ng/mL (IQR)

11.6 (7.3–23.8)

12.1 (10.5–24.1)

10.3 (7.0–23.4)

0.20b

Endocan ng/mL (SD)

2.4 (1.6)

2.5 (1.9)

2.2 (1.4)

0.64a

  1. PBR perfused boundary region
  2. a Student’s t-test
  3. b Mann–Whitney U test