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Table 3 Comparison of biochemical markers between the study groups at 7th day, 30th day and 45th day after birth of preterm infants

From: Continuous versus intermittent bolus infusion of calcium in preterm infants receiving total parenteral nutrition: a randomized blind clinical trial

Variable

Continuous infusion group (n = 40)

Bolus infusion group (n = 38)

P-value†

Serum calcium (mg/dl)

   

7th day

9.2 (1.0)a

9.1 (0.8)

0.638£

30th day

9.0 (0.7)

9.0 (0.6)

0.888£

45th day

8.97 (0.6)

9.2 (0.6)

0.064†

Serum phosphorus (mg/dl)

   

7th day

5.3 (1.2)

5.3 (1.1)

0.973£

30th day

4.2 (0.8)

4.9 (0.8)

0.000£

45th day

4.5 (0.9)

5.0 (0.7)

0.227†

Vitamin D (ng/ml)

   

7th day

33.6 (15.3)

16.1 (10.2)

0.000£

30th day

38.5 (20.4)

18.0 (9.4)

0.000£

45th day

40.8 (19.6)

21.4 (11.0)

0.111†

ALP (IU/L)

   

7th day

529.9 (221.0)

653.4 (198.3)

0.011£

30th day

803.7 (340.5)

959.2 (343.9)

0.048£

45th day

753.2 (304.5)

988.2 (341.3)

0.031†

PTH (IU/L)

   

7th day

70.6 (58.6)

75.5 (55.2)

0.701£

30th day

65.2 (67.3)

76.2 (60.7)

0.453£

45th day

59.5 (57.5)

73.7 (52.9)

0.878†

  1. MD: Mean Difference; ALP: Alkaline Phosphates; PTH: Parathyroid Hormone
  2. a Mean (SD). P-values of statistical significance (p < 0.05) are presented in bold
  3. † Analysis of covariance (adjusted for 30th day values, vitamin D and phosphorous or calcium)
  4. £ Independent t-test