Table 1 Demographic and anthropometric data of enrolled participants
non-rhGH (n = 17) | rhGH (n = 17) | p value | |
|---|---|---|---|
Genotype | 0.71 | ||
Paternal deletion (%) | 11 (64.71) | 13 (76.47) | |
Aberrant methylation (mUPD and imprinting defect) (%) | 6 (35.29) | 4 (23.53) | |
Sex | > 0.05 | ||
Male (%) | 7 (41.12) | 8 (47.06) | |
Female (%) | 10 (58.82) | 9 (52.94) | |
Age (months) | 25.23 ± 13.81 | 20.76 ± 9.22 | 0.59 |
Height/length (m) | 0.84 ± 0.13 | 0.85 ± 0.08 | 0.81 |
Weight (kg) | 13.65 ± 5.26 | 11.38 ± 3.12 | 0.43 |
W/H z-score | 1.08 ± 1.97 | -0.45 ± 1.27 | 0.02 |
Obesity and overweight (%) | 6 (35.29) | 1 (5.89) | 0.03 |
IGF1 z-score | -0.46 ± 0.68 | 1.74 ± 1.75 | < 0.001 |
IGFBP-3 (μg/mL) | 2.17 ± 1.09 | 3.56 ± 1.24 | 0.003 |